Pyrrolidine dithiocarbamate inhibition of luteolin-induced apoptosis through up-regulated phosphorylation of akt and caspase-9 in human leukemia HL-60 cells

Journal of Agricultural and Food Chemistry

Volumn 54, Issue 12, 2006, Pages 4215-4221

  Cheng, An Chin ^a   Huang, Tzou Chi ^b   Lai, Ching Shu ^c   Kuo, Jen Min ^c   Huang, Ying Tang ^c   Lo, Chih Yu ^d   Ho, Chi Tang ^d   Pan, Min Hsiung ^c  

^a Shu Zen College of Medicine and Management   (Taiwan)

^b NATIONAL PINGTUNG UNIVERSITY   (Taiwan)

^c NATIONAL KAOHSIUNG UNIVERSITY OF APPLIED SCIENCES   (Taiwan)

^d RUTGERS UNIVERSITY   (United States)

Author keywords

Akt; Apoptosis; Caspase 9; Luteolin; PDTC (pyrrolidine dithiocarbamate)

Indexed keywords

ANTIOXIDANT; CASP9 PROTEIN, HUMAN; CASPASE; CASPASE 9; CYTOCHROME C; DNA FRAGMENT; DNA FRAGMENTATION FACTOR, HUMAN; LUTEOLIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN; PROTEIN KINASE B; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMIC ACID; THIOCARBAMIC ACID DERIVATIVE;

APOPTOSIS; ARTICLE; CELL MEMBRANE POTENTIAL; CELL STRAIN HL 60; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; METABOLISM; MITOCHONDRION; PHOSPHORYLATION; ULTRASTRUCTURE;

ANTIOXIDANTS; APOPTOSIS; CASPASE 9; CASPASES; CYTOCHROMES C; DNA FRAGMENTATION; FLOW CYTOMETRY; HL-60 CELLS; HUMANS; LUTEOLIN; MEMBRANE POTENTIALS; MITOCHONDRIA; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PYRROLIDINES; THIOCARBAMATES;

EID: 33745755792     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf060269n     Document Type: Article

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