-
1
-
-
18544380930
-
Therapeutic opportunities in Alzheimer disease: One for all or all for one?
-
Marlatt MW, Webber KM, Moreira PI et al (2005) Therapeutic opportunities in Alzheimer disease: one for all or all for one? Curr Med Chem 12:1137-1147
-
(2005)
Curr Med Chem
, vol.12
, pp. 1137-1147
-
-
Marlatt, M.W.1
Webber, K.M.2
Moreira, P.I.3
-
2
-
-
33646855957
-
Neuropathology of Alzheimer disease: Pathognomonic but not pathogenic
-
Castellani RJ, Lee HG, Zhu X et al (2006) Neuropathology of Alzheimer disease: pathognomonic but not pathogenic. Acta Neuropathol (Berl) 111:503-509
-
(2006)
Acta Neuropathol (Berl)
, vol.111
, pp. 503-509
-
-
Castellani, R.J.1
Lee, H.G.2
Zhu, X.3
-
3
-
-
33947151122
-
The cell cycle hypothesis of Alzheimer's disease: Suggestions for drug development
-
Woods J, Snape M, Smith MA (2007) The cell cycle hypothesis of Alzheimer's disease: suggestions for drug development. Biochim Biophys Acta 1772:503-508
-
(2007)
Biochim Biophys Acta
, vol.1772
, pp. 503-508
-
-
Woods, J.1
Snape, M.2
Smith, M.A.3
-
4
-
-
0034839086
-
Systemic iron metabolism: A review and implications for brain iron metabolism
-
Rouault TA (2001) Systemic iron metabolism: a review and implications for brain iron metabolism. Pediatr Neurol 25:130-137
-
(2001)
Pediatr Neurol
, vol.25
, pp. 130-137
-
-
Rouault, T.A.1
-
5
-
-
0034935074
-
Iron on the brain
-
Rouault TA (2001) Iron on the brain. Nat Genet 28:299-300
-
(2001)
Nat Genet
, vol.28
, pp. 299-300
-
-
Rouault, T.A.1
-
6
-
-
0035474950
-
Recent advances in disorders of iron metabolism: Mutations, mechanisms and modifiers
-
Roy CN, Andrews NC (2001) Recent advances in disorders of iron metabolism: mutations, mechanisms and modifiers. Hum Mol Genet 10:2181-2186
-
(2001)
Hum Mol Genet
, vol.10
, pp. 2181-2186
-
-
Roy, C.N.1
Andrews, N.C.2
-
7
-
-
0029976834
-
Immunohistochemical localization of intraneuronal transferrin receptor immunoreactivity in the adult mouse central nervous system
-
Moos T (1996) Immunohistochemical localization of intraneuronal transferrin receptor immunoreactivity in the adult mouse central nervous system. J Comp Neurol 375:675-692
-
(1996)
J Comp Neurol
, vol.375
, pp. 675-692
-
-
Moos, T.1
-
8
-
-
0027723591
-
Lactotransferrin immunocytochemistry in Alzheimer and normal human brain
-
Kawamata T, Tooyama I, Yamada T et al (1993) Lactotransferrin immunocytochemistry in Alzheimer and normal human brain. Am J Pathol 142:1574-1585
-
(1993)
Am J Pathol
, vol.142
, pp. 1574-1585
-
-
Kawamata, T.1
Tooyama, I.2
Yamada, T.3
-
9
-
-
0028321575
-
The iron-binding protein lactotransferrin is present in pathologic lesions in a variety of neurodegenerative disorders: A comparative immunohistochemical analysis
-
Leveugle B, Spik G, Perl DP et al (1994) The iron-binding protein lactotransferrin is present in pathologic lesions in a variety of neurodegenerative disorders: a comparative immunohistochemical analysis. Brain Res 650:20-31
-
(1994)
Brain Res
, vol.650
, pp. 20-31
-
-
Leveugle, B.1
Spik, G.2
Perl, D.P.3
-
10
-
-
0034635402
-
Alternative RNA splicing generates a glycosylphosphatidylinositol- anchored form of ceruloplasmin in mammalian brain
-
Patel BN, Dunn RJ, David S (2000) Alternative RNA splicing generates a glycosylphosphatidylinositol-anchored form of ceruloplasmin in mammalian brain. J Biol Chem 275:4305-4310
-
(2000)
J Biol Chem
, vol.275
, pp. 4305-4310
-
-
Patel, B.N.1
Dunn, R.J.2
David, S.3
-
11
-
-
0029800745
-
Expression of the ceruloplasmin gene in the human retina and brain: Implications for a pathogenic model in aceruloplasminemia
-
Klomp LW, Gitlin JD (1996) Expression of the ceruloplasmin gene in the human retina and brain: implications for a pathogenic model in aceruloplasminemia. Hum Mol Genet 5:1989-1996
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1989-1996
-
-
Klomp, L.W.1
Gitlin, J.D.2
-
12
-
-
0026779690
-
Iron and transferrin uptake by brain and cerebrospinal fluid in the rat
-
Crowe A, Morgan EH (1992) Iron and transferrin uptake by brain and cerebrospinal fluid in the rat. Brain Res 592:8-16
-
(1992)
Brain Res
, vol.592
, pp. 8-16
-
-
Crowe, A.1
Morgan, E.H.2
-
13
-
-
13344275174
-
Discovery of a brain promoter from the human transferrin gene and its utilization for development of transgenic mice that express human apolipoprotein e alleles
-
Bowman BH, Jansen L, Yang F et al (1995) Discovery of a brain promoter from the human transferrin gene and its utilization for development of transgenic mice that express human apolipoprotein E alleles. Proc Natl Acad Sci USA 92:12115-12119
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 12115-12119
-
-
Bowman, B.H.1
Jansen, L.2
Yang, F.3
-
15
-
-
0033769320
-
Structural characteristics of human substantia nigra neuromelanin and synthetic dopamine melanins
-
Double KL, Zecca L, Costi P et al (2000) Structural characteristics of human substantia nigra neuromelanin and synthetic dopamine melanins. J Neurochem 75:2583-2589
-
(2000)
J Neurochem
, vol.75
, pp. 2583-2589
-
-
Double, K.L.1
Zecca, L.2
Costi, P.3
-
16
-
-
0029758487
-
Molecular control of vertebrate iron metabolism: MRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress
-
Hentze MW, Kuhn LC (1996) Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress. Proc Natl Acad Sci USA 93:8175-8182
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8175-8182
-
-
Hentze, M.W.1
Kuhn, L.C.2
-
17
-
-
0034838768
-
Iron and iron management proteins in neurobiology
-
Connor JR, Menzies SL, Burdo JR et al (2001) Iron and iron management proteins in neurobiology. Pediatr Neurol 25:118-129
-
(2001)
Pediatr Neurol
, vol.25
, pp. 118-129
-
-
Connor, J.R.1
Menzies, S.L.2
Burdo, J.R.3
-
18
-
-
0036212575
-
Regional distribution of heme oxygenase, HSP70, and glutathione in brain: Relevance for endogenous oxidant/antioxidant balance and stress tolerance
-
Calabrese V, Scapagnini G, Ravagna A et al (2002) Regional distribution of heme oxygenase, HSP70, and glutathione in brain: relevance for endogenous oxidant/antioxidant balance and stress tolerance. J Neurosci Res 68:65-75
-
(2002)
J Neurosci Res
, vol.68
, pp. 65-75
-
-
Calabrese, V.1
Scapagnini, G.2
Ravagna, A.3
-
19
-
-
0008881566
-
The heme oxygenase system and its functions in the brain
-
Maines MD (2000) The heme oxygenase system and its functions in the brain. Cell Mol Biol (Noisy-le-grand) 46:573-585
-
(2000)
Cell Mol Biol (Noisy-le-grand)
, vol.46
, pp. 573-585
-
-
Maines, M.D.1
-
20
-
-
0032031780
-
Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease
-
Marcus DL, Thomas C, Rodriguez C et al (1998) Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease. Exp Neurol 150:40-44
-
(1998)
Exp Neurol
, vol.150
, pp. 40-44
-
-
Marcus, D.L.1
Thomas, C.2
Rodriguez, C.3
-
21
-
-
0030989545
-
4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
-
Sayre LM, Zelasko DA, Harris PL et al (1997) 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem 68:2092-2097
-
(1997)
J Neurochem
, vol.68
, pp. 2092-2097
-
-
Sayre, L.M.1
Zelasko, D.A.2
Harris, P.L.3
-
22
-
-
0346386580
-
Widespread peroxynitrite-mediated damage in Alzheimer's disease
-
Smith MA, Richey Harris PL, Sayre LM et al (1997) Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci 17:2653-2657
-
(1997)
J Neurosci
, vol.17
, pp. 2653-2657
-
-
Smith, M.A.1
Richey Harris, P.L.2
Sayre, L.M.3
-
23
-
-
0028233977
-
Advanced Maillard reaction end products are associated with Alzheimer disease pathology
-
Smith MA, Taneda S, Richey PL et al (1994) Advanced Maillard reaction end products are associated with Alzheimer disease pathology. Proc Natl Acad Sci USA 91:5710-5714
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5710-5714
-
-
Smith, M.A.1
Taneda, S.2
Richey, P.L.3
-
24
-
-
0029982815
-
Oxidative damage in Alzheimer's
-
Smith MA, Perry G, Richey PL et al (1996) Oxidative damage in Alzheimer's. Nature 382:120-121
-
(1996)
Nature
, vol.382
, pp. 120-121
-
-
Smith, M.A.1
Perry, G.2
Richey, P.L.3
-
25
-
-
0030885482
-
Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
-
Smith MA, Harris PL, Sayre LM et al (1997) Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci USA 94:9866-9868
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9866-9868
-
-
Smith, M.A.1
Harris, P.L.2
Sayre, L.M.3
-
26
-
-
0033559462
-
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease
-
Nunomura A, Perry G, Pappolla MA et al (1999) RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci 19:1959-1964
-
(1999)
J Neurosci
, vol.19
, pp. 1959-1964
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
-
27
-
-
0029159829
-
Free radical formation in autopsy samples of Alzheimer and control cortex
-
Zhou Y, Richardson JS, Mombourquette MJ et al (1995) Free radical formation in autopsy samples of Alzheimer and control cortex. Neurosci Lett 195:89-92
-
(1995)
Neurosci Lett
, vol.195
, pp. 89-92
-
-
Zhou, Y.1
Richardson, J.S.2
Mombourquette, M.J.3
-
28
-
-
0022480081
-
Increased cerebral glucose-6-phosphate dehydrogenase activity in Alzheimer's disease may reflect oxidative stress
-
Martins RN, Harper CG, Stokes GB et al (1986) Increased cerebral glucose-6-phosphate dehydrogenase activity in Alzheimer's disease may reflect oxidative stress. J Neurochem 46:1042-1045
-
(1986)
J Neurochem
, vol.46
, pp. 1042-1045
-
-
Martins, R.N.1
Harper, C.G.2
Stokes, G.B.3
-
29
-
-
0026823074
-
Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease
-
Pappolla MA, Omar RA, Kim KS et al (1992) Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease. Am J Pathol 140:621-628
-
(1992)
Am J Pathol
, vol.140
, pp. 621-628
-
-
Pappolla, M.A.1
Omar, R.A.2
Kim, K.S.3
-
30
-
-
0032507975
-
Copper, iron and zinc in Alzheimer's disease senile plaques
-
Lovell MA, Robertson JD, Teesdale WJ et al (1998) Copper, iron and zinc in Alzheimer's disease senile plaques. J Neurol Sci 158:47-52
-
(1998)
J Neurol Sci
, vol.158
, pp. 47-52
-
-
Lovell, M.A.1
Robertson, J.D.2
Teesdale, W.J.3
-
31
-
-
0028802605
-
Increased amyloid protein precursor and apolipoprotein e immunoreactivity in the selectively vulnerable hippocampus following transient forebrain ischemia in gerbils
-
Hall ED, Oostveen JA, Dunn E et al (1995) Increased amyloid protein precursor and apolipoprotein E immunoreactivity in the selectively vulnerable hippocampus following transient forebrain ischemia in gerbils. Exp Neurol 135:17-27
-
(1995)
Exp Neurol
, vol.135
, pp. 17-27
-
-
Hall, E.D.1
Oostveen, J.A.2
Dunn, E.3
-
32
-
-
0034603414
-
Vascular abnormalities: The insidious pathogenesis of Alzheimer's disease
-
Shi J, Perry G, Smith MA et al (2000) Vascular abnormalities: the insidious pathogenesis of Alzheimer's disease. Neurobiol Aging 21:357-361
-
(2000)
Neurobiol Aging
, vol.21
, pp. 357-361
-
-
Shi, J.1
Perry, G.2
Smith, M.A.3
-
33
-
-
0025845529
-
Induction of amyloid precursor protein mRNA after heat shock in cultured human lymphoblastoid cells
-
Abe K, St George-Hyslop PH, Tanzi RE et al (1991) Induction of amyloid precursor protein mRNA after heat shock in cultured human lymphoblastoid cells. Neurosci Lett 125:169-171
-
(1991)
Neurosci Lett
, vol.125
, pp. 169-171
-
-
Abe, K.1
St George-Hyslop, P.H.2
Tanzi, R.E.3
-
34
-
-
0028865755
-
Ischemic stress induces deposition of amyloid beta immunoreactivity in human brain
-
Jendroska K, Poewe W, Daniel SE et al (1995) Ischemic stress induces deposition of amyloid beta immunoreactivity in human brain. Acta Neuropathol (Berl) 90:461-466
-
(1995)
Acta Neuropathol (Berl)
, vol.90
, pp. 461-466
-
-
Jendroska, K.1
Poewe, W.2
Daniel, S.E.3
-
35
-
-
0031770501
-
Experimental brain injury induces expression of amyloid precursor protein, which may be related to neuronal loss in the hippocampus
-
Murakami N, Yamaki T, Iwamoto Y et al (1998) Experimental brain injury induces expression of amyloid precursor protein, which may be related to neuronal loss in the hippocampus. J Neurotrauma 15:993-1003
-
(1998)
J Neurotrauma
, vol.15
, pp. 993-1003
-
-
Murakami, N.1
Yamaki, T.2
Iwamoto, Y.3
-
36
-
-
0030727701
-
Hypoglycemia enhances the expression of mRNA encoding beta-amyloid precursor protein in rat primary cortical astroglial cells
-
Shi J, Xiang Y, Simpkins JW (1997) Hypoglycemia enhances the expression of mRNA encoding beta-amyloid precursor protein in rat primary cortical astroglial cells. Brain Res 772:247-251
-
(1997)
Brain Res
, vol.772
, pp. 247-251
-
-
Shi, J.1
Xiang, Y.2
Simpkins, J.W.3
-
37
-
-
0032454039
-
Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease
-
Mattson MP, Pedersen WA (1998) Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease. Int J Dev Neurosci 16:737-753
-
(1998)
Int J Dev Neurosci
, vol.16
, pp. 737-753
-
-
Mattson, M.P.1
Pedersen, W.A.2
-
38
-
-
0028200649
-
Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative
-
Gabuzda D, Busciglio J, Chen LB et al (1994) Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative. J Biol Chem 269:13623-13628
-
(1994)
J Biol Chem
, vol.269
, pp. 13623-13628
-
-
Gabuzda, D.1
Busciglio, J.2
Chen, L.B.3
-
39
-
-
0034643895
-
Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells
-
Misonou H, Morishima-Kawashima M, Ihara Y (2000) Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells. Biochemistry (Mosc) 39:6951-6959
-
(2000)
Biochemistry (Mosc)
, vol.39
, pp. 6951-6959
-
-
Misonou, H.1
Morishima-Kawashima, M.2
Ihara, Y.3
-
40
-
-
0034754471
-
Melatonin protects SHSY5Y neuroblastoma cells from cobalt-induced oxidative stress, neurotoxicity and increased beta-amyloid secretion
-
Olivieri G, Hess C, Savaskan E et al (2001) Melatonin protects SHSY5Y neuroblastoma cells from cobalt-induced oxidative stress, neurotoxicity and increased beta-amyloid secretion. J Pineal Res 31:320-325
-
(2001)
J Pineal Res
, vol.31
, pp. 320-325
-
-
Olivieri, G.1
Hess, C.2
Savaskan, E.3
-
41
-
-
0029985732
-
Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid (Abeta) in mammalian lenses, and Abeta has toxic effects on lens epithelial cells
-
Frederikse PH, Garland D, Zigler JS Jr et al (1996) Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid (Abeta) in mammalian lenses, and Abeta has toxic effects on lens epithelial cells. J Biol Chem 271:10169-10174
-
(1996)
J Biol Chem
, vol.271
, pp. 10169-10174
-
-
Frederikse, P.H.1
Garland, D.2
Zigler Jr., J.S.3
-
42
-
-
0034673209
-
Oxidative stress induces increase in intracellular amyloid beta-protein production and selective activation of betaI and betaII PKCs in NT2 cells
-
Paola D, Domenicotti C, Nitti M et al (2000) Oxidative stress induces increase in intracellular amyloid beta-protein production and selective activation of betaI and betaII PKCs in NT2 cells. Biochem Biophys Res Commun 268:642-646
-
(2000)
Biochem Biophys Res Commun
, vol.268
, pp. 642-646
-
-
Paola, D.1
Domenicotti, C.2
Nitti, M.3
-
43
-
-
0033844944
-
Characterization of copper interactions with alzheimer amyloid beta peptides: Identification of an attomolar-affinity copper binding site on amyloid beta1-42
-
Atwood CS, Scarpa RC, Huang X et al (2000) Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42. J Neurochem 75:1219-1233
-
(2000)
J Neurochem
, vol.75
, pp. 1219-1233
-
-
Atwood, C.S.1
Scarpa, R.C.2
Huang, X.3
-
44
-
-
0032557425
-
Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis
-
Atwood CS, Moir RD, Huang X et al (1998) Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis. J Biol Chem 273:12817-12826
-
(1998)
J Biol Chem
, vol.273
, pp. 12817-12826
-
-
Atwood, C.S.1
Moir, R.D.2
Huang, X.3
-
45
-
-
0035827681
-
Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits
-
Curtain CC, Ali F, Volitakis I et al (2001) Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits. J Biol Chem 276:20466-20473
-
(2001)
J Biol Chem
, vol.276
, pp. 20466-20473
-
-
Curtain, C.C.1
Ali, F.2
Volitakis, I.3
-
46
-
-
18344414746
-
The a beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
Huang X, Atwood CS, Hartshorn MA et al (1999) The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry (Mosc) 38:7609-7616
-
(1999)
Biochemistry (Mosc)
, vol.38
, pp. 7609-7616
-
-
Huang, X.1
Atwood, C.S.2
Hartshorn, M.A.3
-
47
-
-
0033515564
-
Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides
-
Dikalov SI, Vitek MP, Maples KR et al (1999) Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides. J Biol Chem 274:9392-9399
-
(1999)
J Biol Chem
, vol.274
, pp. 9392-9399
-
-
Dikalov, S.I.1
Vitek, M.P.2
Maples, K.R.3
-
49
-
-
0034502428
-
Arson. Tracking the culprit in Alzheimer's disease
-
Smith MA, Joseph JA, Perry G (2000) Arson. Tracking the culprit in Alzheimer's disease. Ann NY Acad Sci 924:35-38
-
(2000)
Ann NY Acad Sci
, vol.924
, pp. 35-38
-
-
Smith, M.A.1
Joseph, J.A.2
Perry, G.3
-
50
-
-
0035054836
-
Copernicus revisited: Amyloid beta in Alzheimer's disease
-
Joseph J, Shukitt-Hale B, Denisova NA et al (2001) Copernicus revisited: amyloid beta in Alzheimer's disease. Neurobiol Aging 22:131-146
-
(2001)
Neurobiol Aging
, vol.22
, pp. 131-146
-
-
Joseph, J.1
Shukitt-Hale, B.2
Denisova, N.A.3
-
51
-
-
0035865905
-
Redox-active iron mediates amyloid-beta toxicity
-
Rottkamp CA, Raina AK, Zhu X et al (2001) Redox-active iron mediates amyloid-beta toxicity. Free Radic Biol Med 30:447-450
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 447-450
-
-
Rottkamp, C.A.1
Raina, A.K.2
Zhu, X.3
-
52
-
-
0035997240
-
The state versus amyloid-beta: The trial of the most wanted criminal in Alzheimer disease
-
Rottkamp CA, Atwood CS, Joseph JA et al (2002) The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease. Peptides 23:1333-1341
-
(2002)
Peptides
, vol.23
, pp. 1333-1341
-
-
Rottkamp, C.A.1
Atwood, C.S.2
Joseph, J.A.3
-
53
-
-
0030847015
-
Perivascular astrocytes within Alzheimer's disease plaques
-
Cullen KM (1997) Perivascular astrocytes within Alzheimer's disease plaques. Neuroreport 8:1961-1966
-
(1997)
Neuroreport
, vol.8
, pp. 1961-1966
-
-
Cullen, K.M.1
-
54
-
-
0002419095
-
Cytokines as mediators of chronic inflammatory disease
-
CRC Boca Raton, FL
-
Dunn CJ (1991) Cytokines as mediators of chronic inflammatory disease. In: Kimball ES (ed) Cytokines and inflammation. CRC, Boca Raton, FL, pp 1-33
-
(1991)
Cytokines and Inflammation
, pp. 1-33
-
-
Dunn, C.J.1
Kimball, E.S.2
-
55
-
-
0032557884
-
Activated microglia cause iron-dependent lipid peroxidation in the presence of ferritin
-
Yoshida T, Tanaka M, Sotomatsu A et al (1998) Activated microglia cause iron-dependent lipid peroxidation in the presence of ferritin. Neuroreport 9:1929-1933
-
(1998)
Neuroreport
, vol.9
, pp. 1929-1933
-
-
Yoshida, T.1
Tanaka, M.2
Sotomatsu, A.3
-
56
-
-
0028000830
-
Regulation of the release of interleukin-6 from human astrocytoma cells
-
Cadman ED, Witte DG, Lee CM (1994) Regulation of the release of interleukin-6 from human astrocytoma cells. J Neurochem 63:980-987
-
(1994)
J Neurochem
, vol.63
, pp. 980-987
-
-
Cadman, E.D.1
Witte, D.G.2
Lee, C.M.3
-
57
-
-
0033964859
-
In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: A central role for bound transition metals
-
Sayre LM, Perry G, Harris PL et al (2000) In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals. J Neurochem 74:270-279
-
(2000)
J Neurochem
, vol.74
, pp. 270-279
-
-
Sayre, L.M.1
Perry, G.2
Harris, P.L.3
-
58
-
-
0038417076
-
The identification and characterization of oxidized RNAs in Alzheimer's disease
-
Shan X, Tashiro H, Lin CL (2003) The identification and characterization of oxidized RNAs in Alzheimer's disease. J Neurosci 23:4913-4921
-
(2003)
J Neurosci
, vol.23
, pp. 4913-4921
-
-
Shan, X.1
Tashiro, H.2
Lin, C.L.3
-
59
-
-
20444383489
-
Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron
-
Honda K, Smith MA, Zhu X et al (2005) Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem 280:20978-20986
-
(2005)
J Biol Chem
, vol.280
, pp. 20978-20986
-
-
Honda, K.1
Smith, M.A.2
Zhu, X.3
-
60
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
Hirai K, Aliev G, Nunomura A et al (2001) Mitochondrial abnormalities in Alzheimer's disease. J Neurosci 21:3017-3023
-
(2001)
J Neurosci
, vol.21
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
-
61
-
-
33644480509
-
Detection, identification and mapping of iron anomalies in brain tissue using X-ray absorption spectroscopy
-
Mikhaylova A, Davidson M, Toastmann H et al (2005) Detection, identification and mapping of iron anomalies in brain tissue using X-ray absorption spectroscopy. J R Soc Interface/R Soc 2:33-37
-
(2005)
J R Soc Interface/R Soc
, vol.2
, pp. 33-37
-
-
Mikhaylova, A.1
Davidson, M.2
Toastmann, H.3
-
62
-
-
23944491628
-
In situ characterization and mapping of iron compounds in Alzheimer's disease tissue
-
Collingwood JF, Mikhaylova A, Davidson M et al (2005) In situ characterization and mapping of iron compounds in Alzheimer's disease tissue. J Alzheimers Dis 7:267-272
-
(2005)
J Alzheimers Dis
, vol.7
, pp. 267-272
-
-
Collingwood, J.F.1
Mikhaylova, A.2
Davidson, M.3
-
63
-
-
23944525872
-
High-resolution x-ray absorption spectroscopy studies of metal compounds in neurodegenerative brain tissue
-
Collingwood JF, Mikhaylova A, Davidson MR et al (2005) High-resolution x-ray absorption spectroscopy studies of metal compounds in neurodegenerative brain tissue. J Phys: Conf Ser 17:54-60
-
(2005)
J Phys: Conf Ser
, vol.17
, pp. 54-60
-
-
Collingwood, J.F.1
Mikhaylova, A.2
Davidson, M.R.3
-
64
-
-
0030012126
-
Magnetic properties of human hippocampal tissue-evaluation of artefact and contamination sources
-
Dobson J, Grassi P (1996) Magnetic properties of human hippocampal tissue-evaluation of artefact and contamination sources. Brain Res Bull 39:255-259
-
(1996)
Brain Res Bull
, vol.39
, pp. 255-259
-
-
Dobson, J.1
Grassi, P.2
-
65
-
-
0032958861
-
TEM investigations of biogenic magnetite extracted from the human hippocampus
-
Schultheiss-Grassi PP, Wessiken R, Dobson J (1999) TEM investigations of biogenic magnetite extracted from the human hippocampus. Biochim Biophys Acta 1426:212-216
-
(1999)
Biochim Biophys Acta
, vol.1426
, pp. 212-216
-
-
Schultheiss-Grassi, P.P.1
Wessiken, R.2
Dobson, J.3
-
67
-
-
0043032510
-
Preliminary evaluation of nanoscale biogenic magnetite in Alzheimer's disease brain tissue
-
Suppl 1
-
Hautot D, Pankhurst QA, Khan N et al (2003) Preliminary evaluation of nanoscale biogenic magnetite in Alzheimer's disease brain tissue. Proceedings 270(Suppl 1):S62-S64
-
(2003)
Proceedings
, vol.270
-
-
Hautot, D.1
Pankhurst, Q.A.2
Khan, N.3
-
68
-
-
0035805163
-
Nanoscale biogenic iron oxides and neurodegenerative disease
-
Dobson J (2001) Nanoscale biogenic iron oxides and neurodegenerative disease. FEBS Lett 496:1-5
-
(2001)
FEBS Lett
, vol.496
, pp. 1-5
-
-
Dobson, J.1
-
69
-
-
1842451930
-
Magnetic iron compounds in neurological disorders
-
Dobson J (2004) Magnetic iron compounds in neurological disorders. Ann NY Acad Sci 1012:183-192
-
(2004)
Ann NY Acad Sci
, vol.1012
, pp. 183-192
-
-
Dobson, J.1
-
70
-
-
0002390922
-
Effects of weak magnetic fields on free radical recombination reactions
-
Timmel CR, Till U, Brocklehurst B et al (1998) Effects of weak magnetic fields on free radical recombination reactions. Mol Phys 95:71-89
-
(1998)
Mol Phys
, vol.95
, pp. 71-89
-
-
Timmel, C.R.1
Till, U.2
Brocklehurst, B.3
-
71
-
-
0030915547
-
Dramatic effect of magnetite particles on the dynamics of photogenerated free radicals
-
Scaiano JC, Monahan S, Renaud J (1997) Dramatic effect of magnetite particles on the dynamics of photogenerated free radicals. Photochem Photobiol 65:759-762
-
(1997)
Photochem Photobiol
, vol.65
, pp. 759-762
-
-
Scaiano, J.C.1
Monahan, S.2
Renaud, J.3
-
72
-
-
0036860349
-
Metal complexing agents as therapies for Alzheimer's disease
-
Bush AI (2002) Metal complexing agents as therapies for Alzheimer's disease. Neurobiol Aging 23:1031-1038
-
(2002)
Neurobiol Aging
, vol.23
, pp. 1031-1038
-
-
Bush, A.I.1
-
73
-
-
0346849912
-
Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lession in rats
-
Shachar DB, Kahana N, Kampel V et al (2004) Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lession in rats. Neuropharmacology 46:254-263
-
(2004)
Neuropharmacology
, vol.46
, pp. 254-263
-
-
Shachar, D.B.1
Kahana, N.2
Kampel, V.3
-
74
-
-
33846568415
-
Brain ferritin iron may influence age- and gender-related risks of neurodegeneration
-
Bartzokis G, Tishler TA, Lu PH et al (2007) Brain ferritin iron may influence age- and gender-related risks of neurodegeneration. Neurobiol Aging 28:414-423
-
(2007)
Neurobiol Aging
, vol.28
, pp. 414-423
-
-
Bartzokis, G.1
Tishler, T.A.2
Lu, P.H.3
-
75
-
-
27344439224
-
In vivo magnetic resonance microimaging of individual amyloid plaques in Alzheimer's transgenic mice
-
Jack CR Jr, Wengenack TM, Reyes DA et al (2005) In vivo magnetic resonance microimaging of individual amyloid plaques in Alzheimer's transgenic mice. J Neurosci 25:10041-10048
-
(2005)
J Neurosci
, vol.25
, pp. 10041-10048
-
-
Jack Jr., C.R.1
Wengenack, T.M.2
Reyes, D.A.3
-
76
-
-
10744224267
-
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: A pilot phase 2 clinical trial
-
Ritchie CW, Bush AI, Mackinnon A et al (2003) Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Arch Neurol 60:1685-1691
-
(2003)
Arch Neurol
, vol.60
, pp. 1685-1691
-
-
Ritchie, C.W.1
Bush, A.I.2
MacKinnon, A.3
-
77
-
-
0026050541
-
Would decreased aluminum ingestion reduce the incidence of Alzheimer's disease?
-
McLachlan DR, Kruck TP, Lukiw WJ et al (1991) Would decreased aluminum ingestion reduce the incidence of Alzheimer's disease? CMAJ 145:793-804
-
(1991)
CMAJ
, vol.145
, pp. 793-804
-
-
McLachlan, D.R.1
Kruck, T.P.2
Lukiw, W.J.3
-
78
-
-
25144481422
-
Nanoparticle and other metal chelation therapeutics in Alzheimer disease
-
Liu G, Garrett MR, Men P et al (2005) Nanoparticle and other metal chelation therapeutics in Alzheimer disease. Biochim Biophys Acta 1741:246-252
-
(2005)
Biochim Biophys Acta
, vol.1741
, pp. 246-252
-
-
Liu, G.1
Garrett, M.R.2
Men, P.3
-
79
-
-
0037172424
-
Predicting the failure of amyloid-beta vaccine
-
Smith MA, Atwood CS, Joseph JA et al (2002) Predicting the failure of amyloid-beta vaccine. Lancet 359:1864-1865
-
(2002)
Lancet
, vol.359
, pp. 1864-1865
-
-
Smith, M.A.1
Atwood, C.S.2
Joseph, J.A.3
-
80
-
-
3242737470
-
Challenging the amyloid cascade hypothesis: Senile plaques and amyloid-beta as protective adaptations to Alzheimer disease
-
Lee HG, Casadesus G, Zhu X et al (2004) Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease. Ann NY Acad Sci 1019:1-4
-
(2004)
Ann NY Acad Sci
, vol.1019
, pp. 1-4
-
-
Lee, H.G.1
Casadesus, G.2
Zhu, X.3
-
81
-
-
0242684415
-
Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: A novel therapy for Parkinson's disease
-
Kaur D, Yantiri F, Rajagopalan S et al (2003) Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease. Neuron 37:899-909
-
(2003)
Neuron
, vol.37
, pp. 899-909
-
-
Kaur, D.1
Yantiri, F.2
Rajagopalan, S.3
-
82
-
-
0034964390
-
Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice
-
Cherny RA, Atwood CS, Xilinas ME et al (2001) Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron 30:665-676
-
(2001)
Neuron
, vol.30
, pp. 665-676
-
-
Cherny, R.A.1
Atwood, C.S.2
Xilinas, M.E.3
|