Extrahepatic cholestasis downregulates Oatp1 by TNF-α signalling without affecting Oatp2 and Oatp4 expression and sodium-independent bile salt uptake in rat liver

Liver International

Volumn 27, Issue 8, 2007, Pages 1056-1065

  Geier, Andreas ^a   Dietrich, Christoph G ^a   Trauner, Michael ^b   Gartung, Carsten ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Bile acid transporter; Biliary obstruction; Cytokines; Gene regulation

Indexed keywords

BILE SALT; CHOLIC ACID; MESSENGER RNA; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 2; ORGANIC ANION TRANSPORTER 4; TAUROCHOLIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANION TRANSPORT; ARTICLE; BILE DUCT LIGATION; CONTROLLED STUDY; DOWN REGULATION; EXTRAHEPATIC BILE DUCT OBSTRUCTION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE INACTIVATION; MALE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CHOLATES; CHOLESTASIS, EXTRAHEPATIC; COMMON BILE DUCT; DISEASE MODELS, ANIMAL; DOWN-REGULATION; IMMUNOGLOBULIN G; LIGATION; LIVER; MALE; ORGANIC ANION TRANSPORTERS; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; SIGNAL TRANSDUCTION; SODIUM; TAUROCHOLIC ACID; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34548647553     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2007.01523.x     Document Type: Article

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