Frontiers in Emphysema Research

Seminars in Thoracic and Cardiovascular Surgery

Volumn 19, Issue 2, 2007, Pages 135-141

  Kim, Victor ^a   Rogers, Thomas J ^a   Criner, Gerard J ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

chronic airflow obstruction; COPD; emphysema

Indexed keywords

ANTIINFLAMMATORY AGENT; BRONCHODILATING AGENT; CYTOKINE; OXYGEN; SHORT ACTING DRUG;

AIRWAY OBSTRUCTION; ARTICLE; CELL INFILTRATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; CLINICAL FEATURE; DISEASE ACTIVITY; DISEASE COURSE; DISEASE EXACERBATION; DISEASE MARKER; DISEASE SEVERITY; GENETIC CODE; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; INFLAMMATORY DISEASE; INNATE IMMUNITY; LUNG EMPHYSEMA; LUNG SURGERY; MEDICAL RESEARCH; NONHUMAN; PATHOGENESIS; PATIENT ASSESSMENT; PATIENT MONITORING; PHENOTYPE; RISK ASSESSMENT; RISK FACTOR;

BIOMEDICAL RESEARCH; HUMANS; PROGNOSIS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA;

EID: 34548616030     PISSN: 10430679     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.semtcvs.2007.05.005     Document Type: Article

References (85)

1. Mannino D.M., Homa D.M., Akinbami L.J., et al. Chronic obstructive pulmonary disease surveillance-United States, 1971-2000. MMWR Surveill Summ 51 (2002) 1-16
2. Murray C.J., and Lopez A.D. Evidence-based health policy-lessons from the Global Burden of Disease Study. Science 274 (1996) 740-743
3. National Heart Lung and Blood Institute, National Institutes of Health. Global Initiative for Chronic Obstructive Lung Disease (GOLD) Guidelines, Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease. NHLMI/WHO Workshop Report (2001). http://www.goldcopd.org Available at: http://www.goldcopd.org.
4. American Thoracic Society. Cigarette smoking and health. Am J Respir Crit Care Med 153 (1996) 861-865
5. Minematsu N., Nakamura H., Tateno H., et al. Genetic polymorphism in matrix metalloproteinase-9 and pulmonary emphysema. Biochem Biophys Res Commun 289 (2001) 116-119
6. Zhou M., Huang S.G., Wan H.Y., et al. Genetic polymorphism in matrix metalloproteinase-9 and the susceptibility to chronic obstructive pulmonary disease in Han population of south China. Chin Med J (Engl) 117 (2004) 1481-1484
7. Poller W., Faber J.P., Scholz S., et al. Mis-sense mutation of alpha 1-antichymotrypsin gene associated with chronic lung disease. Lancet 339 (1992) 1538
8. Hirano K., Sakamoto T., Uchida Y., et al. Tissue inhibitor of metalloproteinases-2 gene polymorphisms in chronic obstructive pulmonary disease. Eur Respir J 18 (2001) 748-752
9. He J.Q., Ruan J., Connett J.E., et al. Antioxidant gene polymorphisms and susceptibility to a rapid decline in lung function in smokers. Am J Respir Crit Care Med 166 (2002) 323-328
10. Juul K., Tybjaerg-Hansen A., Marklund S., et al. Genetically increased antioxidative protection and decreased chronic obstructive pulmonary disease. Am J Respir Crit Care Med 173 (2006) 858-864
11. Young R.P., Hopkins R., Black P.N., et al. Functional variants of antioxidant genes in smokers with COPD and in those with normal lung function. Thorax 61 (2006) 394-399
12. Guenegou A., Leynaert B., Benessiano J., et al. Association of lung function decline with the heme oxygenase-1 gene promoter microsatellite polymorphism in a general population sample. Results from the European Community Respiratory Health Survey (ECRHS), France. J Med Genet 43 (2006) e43
13. Yamada N., Yamaya M., Okinaga S., et al. Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. Am J Hum Genet 66 (2000) 187-195
14. Hersh C.P., Demeo D.L., Lange C., et al. Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. Am J Respir Cell Mol Biol 33 (2005) 71-78
15. Sandford A.J., Chagani T., Weir T.D., et al. Susceptibility genes for rapid decline of lung function in the lung health study. Am J Respir Crit Care Med 163 (2001) 469-473
16. Sakao S., Tatsumi K., Igari H., et al. Association of tumor necrosis factor-alpha gene promoter polymorphism with low attenuation areas on high-resolution CT in patients with COPD. Chest 122 (2002) 416-420
17. Celedon J.C., Lange C., Raby B.A., et al. The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD). Hum Mol Genet 13 (2004) 1649-1656
18. Ito I., Nagai S., Hoshino Y., et al. Risk and severity of COPD is associated with the group-specific component of serum globulin 1F allele. Chest 125 (2004) 63-70
19. Takabatake N., Sata M., Inoue S., et al. A novel polymorphism in secretory phospholipase A2-IID is associated with body weight loss in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 172 (2005) 1097-1104
20. Triggiani M., Granata F., Giannattasio G., et al. Secretory phospholipases A2 in inflammatory and allergic diseases: not just enzymes. J Allergy Clin Immunol 116 (2005) 1000-1006
21. Hersh C.P., Demeo D.L., Lazarus R., et al. Genetic association analysis of functional impairment in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 173 (2006) 977-984
22. Demeo D.L., Hersh C.P., Hoffman E.A., et al. Genetic determinants of emphysema distribution in the National Emphysema Treatment Trial. Am J Respir Crit Care Med 176 (2007) 42-48
23. Pierrou S., Broberg P., O'Donnell R.A., et al. Expression of genes involved in oxidative stress responses in airway epithelial cells of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 175 (2007) 577-586
24. Ning W., Li C.J., Kaminski N., et al. Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A 101 (2004) 14895-14900
25. Plymoth A., Lofdahl C.G., Ekberg-Jansson A., et al. Protein expression patterns associated with progression of chronic obstructive pulmonary disease in bronchoalveolar lavage of smokers. Clin Chem 53 (2007) 636-644
26. Majo J., Ghezzo H., and Cosio M.G. Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema. Eur Respir J 17 (2001) 946-953
27. O'Donnell R., Breen D., Wilson S., et al. Inflammatory cells in the airways in COPD. Thorax 61 (2006) 448-454
28. Saetta M., Baraldo S., Corbino L., et al. CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160 (1999) 711-717
29. Saetta M., Mariani M., Panina-Bordignon P., et al. Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 165 (2002) 1404-1409
30. Zhu J., Qiu Y.S., Majumdar S., et al. Exacerbations of Bronchitis: bronchial eosinophilia and gene expression for interleukin-4, interleukin-5, and eosinophil chemoattractants. Am J Respir Crit Care Med 164 (2001) 109-116
31. Aksoy M.O., Yang Y., Ji R., et al. CXCR3 surface expression in human airway epithelial cells: cell cycle dependence and effect on cell proliferation. Am J Physiol Lung Cell Mol Physiol 290 (2006) L909-L918
32. Kelsen S.G., Aksoy M.O., Yang Y., et al. The chemokine receptor CXCR3 and its splice variant are expressed in human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 287 (2004) L584-L591
33. Kim W.D., Kim W.S., Koh Y., et al. Abnormal peripheral blood T-lymphocyte subsets in a subgroup of patients with COPD. Chest 122 (2002) 437-444
34. Chrysofakis G., Tzanakis N., Kyriakoy D., et al. Perforin expression and cytotoxic activity of sputum CD8+ lymphocytes in patients with COPD. Chest 125 (2004) 71-76
35. Peleman R.A., Rytila P.H., Kips J.C., et al. The cellular composition of induced sputum in chronic obstructive pulmonary disease. Eur Respir J 13 (1999) 839-843
36. Rutgers S.R., Postma D.S., ten Hacken N.H., et al. Ongoing airway inflammation in patients with COPD who do not currently smoke. Chest 117 (2000) 262S
37. Tanino M., Betsuyaku T., Takeyabu K., et al. Increased levels of interleukin-8 in BAL fluid from smokers susceptible to pulmonary emphysema. Thorax 57 (2002) 405-411
38. Traves S.L., Culpitt S.V., Russell R.E., et al. Increased levels of the chemokines GROalpha and MCP-1 in sputum samples from patients with COPD. Thorax 57 (2002) 590-595
39. Hiemstra P.S., van Wetering S., and Stolk J. Neutrophil serine proteinases and defensins in chronic obstructive pulmonary disease: effects on pulmonary epithelium. Eur Respir J 12 (1998) 1200-1208
40. MacNee W. Pathogenesis of chronic obstructive pulmonary disease. Proc Am Thorac Soc 2 (2005) 258-266 discussion 290-291
41. Culpitt S.V., Maziak W., Loukidis S., et al. Effect of high dose inhaled steroid on cells, cytokines, and proteases in induced sputum in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160 (1999) 1635-1639
42. Finlay G.A., O'Driscoll L.R., Russell K.J., et al. Matrix metalloproteinase expression and production by alveolar macrophages in emphysema. Am J Respir Crit Care Med 156 (1997) 240-247
43. Molet S., Belleguic C., Lena H., et al. Increase in macrophage elastase (MMP-12) in lungs from patients with chronic obstructive pulmonary disease. Inflamm Res 54 (2005) 31-36
44. Segura-Valdez L., Pardo A., Gaxiola M., et al. Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD. Chest 117 (2000) 684-694
45. Selman M., Cisneros-Lira J., Gaxiola M., et al. Matrix metalloproteinases inhibition attenuates tobacco smoke-induced emphysema in Guinea pigs. Chest 123 (2003) 1633-1641
46. Pepys M.B., and Hirschfield G.M. C-reactive protein: a critical update. J Clin Invest 111 (2003) 1805-1812
47. Man S.F., Connett J.E., Anthonisen N.R., et al. C-reactive protein and mortality in mild to moderate chronic obstructive pulmonary disease. Thorax 61 (2006) 849-853
48. Dahl M., Vestbo J., Lange P., et al. C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 175 (2007) 250-255
49. Calikoglu M., Sahin G., Unlu A., et al. Leptin and TNF-alpha levels in patients with chronic obstructive pulmonary disease and their relationship to nutritional parameters. Respiration 71 (2004) 45-50
50. Spruit M.A., Gosselink R., Troosters T., et al. Muscle force during an acute exacerbation in hospitalised patients with COPD and its relationship with CXCL8 and IGF-I. Thorax 58 (2003) 752-756
51. Wedzicha J.A., Seemungal T.A., MacCallum P.K., et al. Acute exacerbations of chronic obstructive pulmonary disease are accompanied by elevations of plasma fibrinogen and serum IL-6 levels. Thromb Haemost 84 (2000) 210-215
52. Yamamoto C., Yoneda T., Yoshikawa M., et al. Airway inflammation in COPD assessed by sputum levels of interleukin-8. Chest 112 (1997) 505-510
53. Crooks S.W., Bayley D.L., Hill S.L., et al. Bronchial inflammation in acute bacterial exacerbations of chronic bronchitis: the role of leukotriene B4. Eur Respir J 15 (2000) 274-280
54. Gompertz S., O'Brien C., Bayley D.L., et al. Changes in bronchial inflammation during acute exacerbations of chronic bronchitis. Eur Respir J 17 (2001) 1112-1119
55. Churg A., Wang R.D., Tai H., et al. Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse. Am J Respir Crit Care Med 170 (2004) 492-498
56. Bhowmik A., Seemungal T.A., Sapsford R.J., et al. Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations. Thorax 55 (2000) 114-120
57. Bucchioni E., Kharitonov S.A., Allegra L., et al. High levels of interleukin-6 in the exhaled breath condensate of patients with COPD. Respir Med 97 (2003) 1299-1302
58. Barcelo B., Pons J., Fuster A., et al. Intracellular cytokine profile of T lymphocytes in patients with chronic obstructive pulmonary disease. Clin Exp Immunol 145 (2006) 474-479
59. Panzner P., Lafitte J.J., Tsicopoulos A., et al. Marked up-regulation of T lymphocytes and expression of interleukin-9 in bronchial biopsies from patients With chronic bronchitis with obstruction. Chest 124 (2003) 1909-1915
60. Borish L., Aarons A., Rumbyrt J., et al. Interleukin-10 regulation in normal subjects and patients with asthma. J Allergy Clin Immunol 97 (1996) 1288-1296
61. Takanashi S., Hasegawa Y., Kanehira Y., et al. Interleukin-10 level in sputum is reduced in bronchial asthma, COPD and in smokers. Eur Respir J 14 (1999) 309-314
62. Ciccolella D.E., Rogers T.J., and Criner G.J. Systemic levels of IL-8 are elevated in patients with COPD exacerbation. [abstract]. Proc Am Thorac Soc 3 (2006) A626
63. Rahman I., and Adcock I.M. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Respir J 28 (2006) 219-242
64. Rahman I., and MacNee W. Role of transcription factors in inflammatory lung diseases. Thorax 53 (1998) 601-612
65. Hecht S.S. Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 91 (1999) 1194-1210
66. Yang S.R., Chida A.S., Bauter M.R., et al. Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages. Am J Physiol Lung Cell Mol Physiol 291 (2006) L46-L57
67. Pryor W.A. Cigarette smoke radicals and the role of free radicals in chemical carcinogenicity. Environ Health Perspect 105 suppl 4 (1997) 875-882
68. Rahman I. Oxidative stress, chromatin remodeling and gene transcription in inflammation and chronic lung diseases. J Biochem Mol Biol 36 (2003) 95-109
69. Kerkvliet N.I., Shepherd D.M., and Baecher-Steppan L. T lymphocytes are direct, aryl hydrocarbon receptor (AhR)-dependent targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): AhR expression in both CD4+ and CD8+ T cells is necessary for full suppression of a cytotoxic T lymphocyte response by TCDD. Toxicol Appl Pharmacol 185 (2002) 146-152
70. Borovikova L.V., Ivanova S., Zhang M., et al. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 405 (2000) 458-462
71. Matsunaga K., Klein T.W., Friedman H., et al. Involvement of nicotinic acetylcholine receptors in suppression of antimicrobial activity and cytokine responses of alveolar macrophages to Legionella pneumophila infection by nicotine. J Immunol 167 (2001) 6518-6524
72. Wang H., Yu M., Ochani M., et al. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 421 (2003) 384-388
73. de Jonge W.J., van der Zanden E.P., The F.O., et al. Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway. Nat Immunol 6 (2005) 844-851
74. Massaro G.D., and Massaro D. Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats. Nat Med 3 (1997) 675-677
75. Ishizawa K., Kubo H., Yamada M., et al. Bone marrow-derived cells contribute to lung regeneration after elastase-induced pulmonary emphysema. FEBS Lett 556 (2004) 249-252
76. Murakami S., Nagaya N., Itoh T., et al. Adrenomedullin regenerates alveoli and vasculature in elastase-induced pulmonary emphysema in mice. Am J Respir Crit Care Med 172 (2005) 581-589
77. Shigemura N., Sawa Y., Mizuno S., et al. Amelioration of pulmonary emphysema by in vivo gene transfection with hepatocyte growth factor in rats. Circulation 111 (2005) 1407-1414
78. Lucey E.C., Goldstein R.H., Breuer R., et al. Retinoic acid does not affect alveolar septation in adult FVB mice with elastase-induced emphysema. Respiration 70 (2003) 200-205
79. March T.H., Cossey P.Y., Esparza D.C., et al. Inhalation administration of all-trans-retinoic acid for treatment of elastase-induced pulmonary emphysema in Fischer 344 rats. Exp Lung Res 30 (2004) 383-404
80. Roth M.D., Connett J.E., D'Armiento J.M., et al. Feasibility of retinoids for the treatment of emphysema study. Chest 130 (2006) 1334-1345
81. Liebow A.A. Pulmonary emphysema with special reference to vascular changes. Am Rev Respir Dis 80 (1959) 67-93
82. Kasahara Y., Tuder R.M., Taraseviciene-Stewart L., et al. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J Clin Invest 106 (2000) 1311-1319
83. Tang K., Rossiter H.B., Wagner P.D., et al. Lung-targeted VEGF inactivation leads to an emphysema phenotype in mice. J Appl Physiol 97 (2004) 1559-1566 discussion 1549
84. Tuder R.M., Zhen L., Cho C.Y., et al. Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. Am J Respir Cell Mol Biol 29 (2003) 88-97
85. Taraseviciene-Stewart L., Scerbavicius R., Choe K.H., et al. An animal model of autoimmune emphysema. Am J Respir Crit Care Med 171 (2005) 734-742