-
1
-
-
21544450545
-
p53 Mediates cellular dysfunction and behavioral abnormalities in Huntington's disease
-
Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y, Hayward SD, Moran TH, Montell C, Ross CA, Snyder SH, Sawa A. 2005. p53 Mediates cellular dysfunction and behavioral abnormalities in Huntington's disease. Neuron 47:29-41.
-
(2005)
Neuron
, vol.47
, pp. 29-41
-
-
Bae, B.I.1
Xu, H.2
Igarashi, S.3
Fujimuro, M.4
Agrawal, N.5
Taya, Y.6
Hayward, S.D.7
Moran, T.H.8
Montell, C.9
Ross, C.A.10
Snyder, S.H.11
Sawa, A.12
-
3
-
-
0034237719
-
Energetics in the pathogenesis of neurodegenerative diseases
-
Beal MF. 2000. Energetics in the pathogenesis of neurodegenerative diseases. Trends Neurosci 23:298-304.
-
(2000)
Trends Neurosci
, vol.23
, pp. 298-304
-
-
Beal, M.F.1
-
4
-
-
4344573714
-
Adult neuron survival strategies - slamming on the brakes
-
Benn SC, Woolf CJ. 2004. Adult neuron survival strategies - slamming on the brakes. Nat Rev Neurosci 5:686-700.
-
(2004)
Nat Rev Neurosci
, vol.5
, pp. 686-700
-
-
Benn, S.C.1
Woolf, C.J.2
-
5
-
-
9444286388
-
Expression of normal and mutant huntingtin in the developing brain
-
Bhide PG, Day M, Sapp E, Schwarz C, Sheth A, Kim J, Young AB, Penney J, Golden J, Aronin N, DiFiglia M. 1996. Expression of normal and mutant huntingtin in the developing brain. J Neurosci 16:5523-5535.
-
(1996)
J Neurosci
, vol.16
, pp. 5523-5535
-
-
Bhide, P.G.1
Day, M.2
Sapp, E.3
Schwarz, C.4
Sheth, A.5
Kim, J.6
Young, A.B.7
Penney, J.8
Golden, J.9
Aronin, N.10
DiFiglia, M.11
-
6
-
-
4444350918
-
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease
-
Canals JM, Pineda JR, Torres-Peraza JF, Bosch M, Martin-Ibanez R, Munoz MT, Mengod G, Ernfors P, Alberch J. 2004. Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease. J Neurosci 24:7727-7739.
-
(2004)
J Neurosci
, vol.24
, pp. 7727-7739
-
-
Canals, J.M.1
Pineda, J.R.2
Torres-Peraza, J.F.3
Bosch, M.4
Martin-Ibanez, R.5
Munoz, M.T.6
Mengod, G.7
Ernfors, P.8
Alberch, J.9
-
7
-
-
0036716281
-
The Bcl2 family: Regulators of the cellular life-or-death switch
-
Cory S, Adams JM. 2002. The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2:647-656.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
8
-
-
0023750525
-
Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease
-
de la Monte SM, Vonsattel JP, Richardson EP Jr. 1988. Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease. J Neuropathol Exp Neurol 47:516-525.
-
(1988)
J Neuropathol Exp Neurol
, vol.47
, pp. 516-525
-
-
de la Monte, S.M.1
Vonsattel, J.P.2
Richardson Jr., E.P.3
-
9
-
-
27144534486
-
Full motor recovery despite striatal neuron loss and formation of irreversible amyloid-like inclusions in a conditional mouse model of Huntington's disease
-
Diaz-Hernandez M, Torres-Peraza J, Salvatori-Abarca A, Moran MA, Gomez-Ramos P, Alberch J, Lucas JJ. 2005. Full motor recovery despite striatal neuron loss and formation of irreversible amyloid-like inclusions in a conditional mouse model of Huntington's disease. J Neurosci 25:9773-9781.
-
(2005)
J Neurosci
, vol.25
, pp. 9773-9781
-
-
Diaz-Hernandez, M.1
Torres-Peraza, J.2
Salvatori-Abarca, A.3
Moran, M.A.4
Gomez-Ramos, P.5
Alberch, J.6
Lucas, J.J.7
-
10
-
-
0029040355
-
In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobes
-
Dragunow M, Faull RL, Lawlor P, Beilharz EJ, Singleton K, Walker EB, Mee E. 1995. In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobes. Neuroreport 6:1053-1057.
-
(1995)
Neuroreport
, vol.6
, pp. 1053-1057
-
-
Dragunow, M.1
Faull, R.L.2
Lawlor, P.3
Beilharz, E.J.4
Singleton, K.5
Walker, E.B.6
Mee, E.7
-
11
-
-
0028274040
-
Mice lacking brain-derived neurotrophic factor develop with sensory deficits
-
Ernfors P, Lee KF, Jaenisch R. 1994. Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature 368:147-150.
-
(1994)
Nature
, vol.368
, pp. 147-150
-
-
Ernfors, P.1
Lee, K.F.2
Jaenisch, R.3
-
12
-
-
0037334339
-
At the acidic edge: Emerging functions for lysosomal membrane proteins
-
Eskelinen EL, Tanaka Y, Saftig P. 2003. At the acidic edge: emerging functions for lysosomal membrane proteins. Trends Cell Biol 13:137-145.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 137-145
-
-
Eskelinen, E.L.1
Tanaka, Y.2
Saftig, P.3
-
13
-
-
33745966804
-
BH3-only proteins: Orchestrating cell death
-
Fletcher JI, Huang DC. 2006. BH3-only proteins: orchestrating cell death. Cell Death Differ 13:1268-1271.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1268-1271
-
-
Fletcher, J.I.1
Huang, D.C.2
-
14
-
-
1642497588
-
Death of cortical and striatal neurons induced by mitochondrial defect involves differential molecular mechanisms
-
Galas MC, Bizat N, Cuvelier L, Bantubungi K, Brouillet E, Schiffmann SN, Blum D. 2004. Death of cortical and striatal neurons induced by mitochondrial defect involves differential molecular mechanisms. Neurobiol Dis 15:152-159.
-
(2004)
Neurobiol Dis
, vol.15
, pp. 152-159
-
-
Galas, M.C.1
Bizat, N.2
Cuvelier, L.3
Bantubungi, K.4
Brouillet, E.5
Schiffmann, S.N.6
Blum, D.7
-
15
-
-
3142636768
-
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
-
Gauthier LR, Charrin BC, Borrell-Pages M, Dompierre JP, Rangone H, Cordelieres FP, De MJ, MacDonald ME, Lessmann V, Humbert S, Saudou F. 2004. Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118:127-138.
-
(2004)
Cell
, vol.118
, pp. 127-138
-
-
Gauthier, L.R.1
Charrin, B.C.2
Borrell-Pages, M.3
Dompierre, J.P.4
Rangone, H.5
Cordelieres, F.P.6
De, M.J.7
MacDonald, M.E.8
Lessmann, V.9
Humbert, S.10
Saudou, F.11
-
16
-
-
33644956205
-
Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain
-
Gines S, Bosch M, Marco S, Gavalda N, Diaz-Hernandez M, Lucas JJ, Canals JM, Alberch J. 2006. Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain. Eur J Neurosci 23:649-658.
-
(2006)
Eur J Neurosci
, vol.23
, pp. 649-658
-
-
Gines, S.1
Bosch, M.2
Marco, S.3
Gavalda, N.4
Diaz-Hernandez, M.5
Lucas, J.J.6
Canals, J.M.7
Alberch, J.8
-
17
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
Gozuacik D, Kimchi A. 2004. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 23:2891-2906.
-
(2004)
Oncogene
, vol.23
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
18
-
-
7444243152
-
Survival factor-induced extracellular signal-regulated kinase phosphorylates Bim, inhibiting its association with Bax and proapoptotic activity
-
Harada H, Quearry B, Ruiz-Vela A, Korsmeyer SJ. 2004. Survival factor-induced extracellular signal-regulated kinase phosphorylates Bim, inhibiting its association with Bax and proapoptotic activity. Proc Natl Acad Sci U S A 101:15313-15317.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 15313-15317
-
-
Harada, H.1
Quearry, B.2
Ruiz-Vela, A.3
Korsmeyer, S.J.4
-
19
-
-
0033635733
-
BH3-only proteins - essential initiators of apoptotic cell death
-
Huang DC, Strasser A. 2000. BH3-only proteins - essential initiators of apoptotic cell death. Cell 103:839-842.
-
(2000)
Cell
, vol.103
, pp. 839-842
-
-
Huang, D.C.1
Strasser, A.2
-
20
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group
-
Huntington's Disease Collaborative Research Group. 1993. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72:971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
21
-
-
0034307476
-
Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy
-
Kegel KB, Kim M, Sapp E, McIntyre C, Castano JG, Aronin N, DiFiglia M. 2000. Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy. J Neurosci 20:7268-7278.
-
(2000)
J Neurosci
, vol.20
, pp. 7268-7278
-
-
Kegel, K.B.1
Kim, M.2
Sapp, E.3
McIntyre, C.4
Castano, J.G.5
Aronin, N.6
DiFiglia, M.7
-
22
-
-
0036124326
-
Expression of Bcl-2 family member Bid in normal and malignant tissues
-
Krajewska M, Zapata JM, Meinhold-Heerlein I, Hedayat H, Monks A, Bettendorf H, Shabaik A, Bubendorf L, Kallioniemi OP, Kim H, Reifenberger G, Reed JC, Krajewski S. 2002. Expression of Bcl-2 family member Bid in normal and malignant tissues. Neoplasia 4:129-140.
-
(2002)
Neoplasia
, vol.4
, pp. 129-140
-
-
Krajewska, M.1
Zapata, J.M.2
Meinhold-Heerlein, I.3
Hedayat, H.4
Monks, A.5
Bettendorf, H.6
Shabaik, A.7
Bubendorf, L.8
Kallioniemi, O.P.9
Kim, H.10
Reifenberger, G.11
Reed, J.C.12
Krajewski, S.13
-
23
-
-
23044514254
-
Regulatory phosphorylation of Bim: Sorting out the ERK from the JNK
-
Ley R, Ewings KE, Hadfield K, Cook SJ. 2005. Regulatory phosphorylation of Bim: sorting out the ERK from the JNK. Cell Death Differ 12:1008-1014.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1008-1014
-
-
Ley, R.1
Ewings, K.E.2
Hadfield, K.3
Cook, S.J.4
-
24
-
-
0031758859
-
Involvement of specific caspases in motoneuron cell death in vivo and in vitro following trophic factor deprivation
-
Li L, Prevette D, Oppenheim RW, Milligan CE. 1998. Involvement of specific caspases in motoneuron cell death in vivo and in vitro following trophic factor deprivation. Mol Cell Neurosci 12:157-167.
-
(1998)
Mol Cell Neurosci
, vol.12
, pp. 157-167
-
-
Li, L.1
Prevette, D.2
Oppenheim, R.W.3
Milligan, C.E.4
-
25
-
-
4544293517
-
Huntingtin and its role in neuronal degeneration
-
Li SH, Li XJ. 2004. Huntingtin and its role in neuronal degeneration. Neuroscientist 10:467-475.
-
(2004)
Neuroscientist
, vol.10
, pp. 467-475
-
-
Li, S.H.1
Li, X.J.2
-
26
-
-
58149288697
-
Down-regulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not ectoposide or cisplatin-induced cell death
-
E-pub ahead of print
-
Li Z, Zhang J, Liu Z, Woo C-W, Thiele CJ. 2006. Down-regulation of Bim by brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from paclitaxel but not ectoposide or cisplatin-induced cell death. Cell Death Differ [E-pub ahead of print].
-
(2006)
Cell Death Differ
-
-
Li, Z.1
Zhang, J.2
Liu, Z.3
Woo, C.-W.4
Thiele, C.J.5
-
27
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu X, Kim CN, Yang J, Jemmerson R, Wang X. 1996. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86:147-157.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
28
-
-
0036403826
-
Pyramidal cell loss in motor cortices in Huntington's disease
-
MacDonald V, Halliday G. 2002. Pyramidal cell loss in motor cortices in Huntington's disease. Neurobiol Dis 10:378-386.
-
(2002)
Neurobiol Dis
, vol.10
, pp. 378-386
-
-
MacDonald, V.1
Halliday, G.2
-
29
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L, Sathasivam K, Seller M, Cozens B, Harper A, Hetherington C, Lawton M, Trottier Y, Lehrach H, Davies SW, Bates GP. 1996. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 87:493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
30
-
-
0027231818
-
The topographic distribution of brain atrophy in Huntington's disease and progressive supranuclear palsy
-
Mann DM, Oliver R, Snowden JS. 1993. The topographic distribution of brain atrophy in Huntington's disease and progressive supranuclear palsy. Acta Neuropathol 85:553-559.
-
(1993)
Acta Neuropathol
, vol.85
, pp. 553-559
-
-
Mann, D.M.1
Oliver, R.2
Snowden, J.S.3
-
31
-
-
0022876328
-
Huntington's disease. Pathogenesis and management
-
Martin JB, Gusella JF. 1986. Huntington's disease. Pathogenesis and management. N Engl J Med 315:1267-1276.
-
(1986)
N Engl J Med
, vol.315
, pp. 1267-1276
-
-
Martin, J.B.1
Gusella, J.F.2
-
32
-
-
0033883377
-
The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells
-
O'Reilly LA, Cullen L, Visvader J, Lindeman GJ, Print C, Bath ML, Huang DC, Strasser A. 2000. The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells. Am J Pathol 157:449-461.
-
(2000)
Am J Pathol
, vol.157
, pp. 449-461
-
-
O'Reilly, L.A.1
Cullen, L.2
Visvader, J.3
Lindeman, G.J.4
Print, C.5
Bath, M.L.6
Huang, D.C.7
Strasser, A.8
-
33
-
-
13244296828
-
Brain-derived neurotrophic factor prevents changes in Bcl-2 family members and caspase-3 activation induced by excitotoxicity in the striatum
-
Perez-Navarro E, Gavalda N, Gratacos E, Alberch J. 2005. Brain-derived neurotrophic factor prevents changes in Bcl-2 family members and caspase-3 activation induced by excitotoxicity in the striatum. J Neurochem 92:678-691.
-
(2005)
J Neurochem
, vol.92
, pp. 678-691
-
-
Perez-Navarro, E.1
Gavalda, N.2
Gratacos, E.3
Alberch, J.4
-
34
-
-
0032912386
-
Recent advances on the pathogenesis of Huntington's disease
-
Petersen A, Mani K, Brundin P. 1999. Recent advances on the pathogenesis of Huntington's disease. Exp Neurol 157:1-18.
-
(1999)
Exp Neurol
, vol.157
, pp. 1-18
-
-
Petersen, A.1
Mani, K.2
Brundin, P.3
-
35
-
-
4544298249
-
Mitochondrial mechanisms of neural cell apoptosis
-
Polster BM, Fiskum G. 2004. Mitochondrial mechanisms of neural cell apoptosis. J Neurochem 90:1281-1289.
-
(2004)
J Neurochem
, vol.90
, pp. 1281-1289
-
-
Polster, B.M.1
Fiskum, G.2
-
36
-
-
0029072690
-
Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models
-
Portera-Cailliau C, Hedreen JC, Price DL, Koliatsos VE. 1995. Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models. J Neurosci 15:3775-3787.
-
(1995)
J Neurosci
, vol.15
, pp. 3775-3787
-
-
Portera-Cailliau, C.1
Hedreen, J.C.2
Price, D.L.3
Koliatsos, V.E.4
-
38
-
-
0141705360
-
Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: Implications for the pathogenesis of neurodegenerative diseases
-
Rego AC, Oliveira CR. 2003. Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases. Neurochem Res 28:1563-1574.
-
(2003)
Neurochem Res
, vol.28
, pp. 1563-1574
-
-
Rego, A.C.1
Oliveira, C.R.2
-
39
-
-
0037518224
-
BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts
-
Sarig R, Zaltsman Y, Marcellus RC, Flavell R, Mak TW, Gross A. 2003. BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts. J Biol Chem 278:10707-10715.
-
(2003)
J Biol Chem
, vol.278
, pp. 10707-10715
-
-
Sarig, R.1
Zaltsman, Y.2
Marcellus, R.C.3
Flavell, R.4
Mak, T.W.5
Gross, A.6
-
40
-
-
0034920108
-
Mechanisms for neuronal cell death and dysfunction in Huntington's disease: Pathological cross-talk between the nucleus and the mitochondria?
-
Sawa A. 2001. Mechanisms for neuronal cell death and dysfunction in Huntington's disease: pathological cross-talk between the nucleus and the mitochondria? J Mol Med 79:375-381.
-
(2001)
J Mol Med
, vol.79
, pp. 375-381
-
-
Sawa, A.1
-
41
-
-
0038751860
-
p53 downstream targets and chemosensitivity
-
Sax JK, El-Deiry WS. 2003. p53 downstream targets and chemosensitivity. Cell Death Differ 10:413-417.
-
(2003)
Cell Death Differ
, vol.10
, pp. 413-417
-
-
Sax, J.K.1
El-Deiry, W.S.2
-
42
-
-
0027432418
-
Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues
-
Strong TV, Tagle DA, Valdes JM, Elmer LW, Boehm K, Swaroop M, Kaatz KW, Collins FS, Albin RL. 1993. Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues. Nat Genet 5:259-265.
-
(1993)
Nat Genet
, vol.5
, pp. 259-265
-
-
Strong, T.V.1
Tagle, D.A.2
Valdes, J.M.3
Elmer, L.W.4
Boehm, K.5
Swaroop, M.6
Kaatz, K.W.7
Collins, F.S.8
Albin, R.L.9
-
43
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM, Mangion J, Jacotot E, Costantini P, Loeffler M, Larochette N, Goodlett DR, Aebersold R, Siderovski DP, Penninger JM, Kroemer G. 1999. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397:441-446.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
Mangion, J.7
Jacotot, E.8
Costantini, P.9
Loeffler, M.10
Larochette, N.11
Goodlett, D.R.12
Aebersold, R.13
Siderovski, D.P.14
Penninger, J.M.15
Kroemer, G.16
-
44
-
-
0029086807
-
DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions
-
Thomas LB, Gates DJ, Richfield EK, O'Brien TF, Schweitzer JB, Steindler DA. 1995. DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions. Exp Neurol 133:265-272.
-
(1995)
Exp Neurol
, vol.133
, pp. 265-272
-
-
Thomas, L.B.1
Gates, D.J.2
Richfield, E.K.3
O'Brien, T.F.4
Schweitzer, J.B.5
Steindler, D.A.6
-
45
-
-
33845205770
-
Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-D-aspartate receptors
-
Torres-Peraza J, Pezzi S, Canals JM, Gavalda N, Garcia-Martinez JM, Perez-Navarro E, Alberch J. 2007. Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-D-aspartate receptors. Neuroscience 144:462-471.
-
(2007)
Neuroscience
, vol.144
, pp. 462-471
-
-
Torres-Peraza, J.1
Pezzi, S.2
Canals, J.M.3
Gavalda, N.4
Garcia-Martinez, J.M.5
Perez-Navarro, E.6
Alberch, J.7
-
46
-
-
0034703869
-
Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells
-
Trettel F, Rigamonti D, Hilditch-Maguire P, Wheeler VC, Sharp AH, Persichetti F, Cattaneo E, MacDonald ME. 2000. Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells. Hum Mol Genet 9:2799-2809.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2799-2809
-
-
Trettel, F.1
Rigamonti, D.2
Hilditch-Maguire, P.3
Wheeler, V.C.4
Sharp, A.H.5
Persichetti, F.6
Cattaneo, E.7
MacDonald, M.E.8
-
47
-
-
23844440646
-
Expression pattern of apoptosis-related markers in Huntington's disease
-
Vis JC, Schipper E, de Boer-van Huizen RT, Verbeek MM, de Waal RM, Wesseling P, ten Donkelaar HJ, Kremer B. 2005. Expression pattern of apoptosis-related markers in Huntington's disease. Acta Neuropathol 109:321-328.
-
(2005)
Acta Neuropathol
, vol.109
, pp. 321-328
-
-
Vis, J.C.1
Schipper, E.2
de Boer-van Huizen, R.T.3
Verbeek, M.M.4
de Waal, R.M.5
Wesseling, P.6
ten Donkelaar, H.J.7
Kremer, B.8
-
49
-
-
10244221103
-
Neuronal apoptosis: BH3-only proteins the real killers?
-
Ward MW, Kogel D, Prehn JH. 2004. Neuronal apoptosis: BH3-only proteins the real killers? J Bioenerg Biomembr 36:295-298.
-
(2004)
J Bioenerg Biomembr
, vol.36
, pp. 295-298
-
-
Ward, M.W.1
Kogel, D.2
Prehn, J.H.3
-
50
-
-
33646838466
-
Real time single cell analysis of Bid cleavage and Bid translocation during caspase-dependent and neuronal caspase-independent apoptosis
-
Ward MW, Rehm M, Duessmann H, Kacmar S, Concannon CG, Prehn JH. 2006. Real time single cell analysis of Bid cleavage and Bid translocation during caspase-dependent and neuronal caspase-independent apoptosis. J Biol Chem 281:5837-5844.
-
(2006)
J Biol Chem
, vol.281
, pp. 5837-5844
-
-
Ward, M.W.1
Rehm, M.2
Duessmann, H.3
Kacmar, S.4
Concannon, C.G.5
Prehn, J.H.6
-
51
-
-
16244409485
-
Brief exposure to NMDA produces long-term protection of cerebellar granule cells from apoptosis
-
Xifro X, Malagelada C, Minano A, Rodriguez-Alvarez J. 2005. Brief exposure to NMDA produces long-term protection of cerebellar granule cells from apoptosis. Eur J Neurosci 21:827-840.
-
(2005)
Eur J Neurosci
, vol.21
, pp. 827-840
-
-
Xifro, X.1
Malagelada, C.2
Minano, A.3
Rodriguez-Alvarez, J.4
-
53
-
-
0034737299
-
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease
-
Yamamoto A, Lucas JJ, Hen R. 2000. Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease. Cell 101:57-66.
-
(2000)
Cell
, vol.101
, pp. 57-66
-
-
Yamamoto, A.1
Lucas, J.J.2
Hen, R.3
-
54
-
-
0034534795
-
Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis
-
Zha J, Weiler S, Oh KJ, Wei MC, Korsmeyer SJ. 2000. Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis. Science 290:1761-1765.
-
(2000)
Science
, vol.290
, pp. 1761-1765
-
-
Zha, J.1
Weiler, S.2
Oh, K.J.3
Wei, M.C.4
Korsmeyer, S.J.5
-
55
-
-
0141531987
-
Depletion of wild-type huntingtin in mouse models of neurologic diseases
-
Zhang Y, Li M, Drozda M, Chen M, Ren S, Mejia Sanchez RO, Leavitt BR, Cattaneo E, Ferrante RJ, Hayden MR, Friedlander RM. 2003a. Depletion of wild-type huntingtin in mouse models of neurologic diseases. J Neurochem 87:101-106.
-
(2003)
J Neurochem
, vol.87
, pp. 101-106
-
-
Zhang, Y.1
Li, M.2
Drozda, M.3
Chen, M.4
Ren, S.5
Mejia Sanchez, R.O.6
Leavitt, B.R.7
Cattaneo, E.8
Ferrante, R.J.9
Hayden, M.R.10
Friedlander, R.M.11
-
56
-
-
0344010993
-
Sequential activation of individual caspases, and of alterations in Bcl-2 proapoptotic signals in a mouse model of Huntington's disease
-
Zhang Y, Ona VO, Li M, Drozda M, Dubois-Dauphin M, Przedborski S, Ferrante RJ, Friedlander RM. 2003b. Sequential activation of individual caspases, and of alterations in Bcl-2 proapoptotic signals in a mouse model of Huntington's disease. J Neurochem 87:1184-1192.
-
(2003)
J Neurochem
, vol.87
, pp. 1184-1192
-
-
Zhang, Y.1
Ona, V.O.2
Li, M.3
Drozda, M.4
Dubois-Dauphin, M.5
Przedborski, S.6
Ferrante, R.J.7
Friedlander, R.M.8
-
57
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. 1997. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90:405-413.
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
58
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
Zuccato C, Ciammola A, Rigamonti D, Leavitt BR, Goffredo D, Conti L, MacDonald ME, Friedlander RM, Silani V, Hayden MR, Timmusk T, Sipione S, Cattaneo E. 2001. Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science 293:493-498.
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
Timmusk, T.11
Sipione, S.12
Cattaneo, E.13
-
59
-
-
0041353535
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
Zuccato C, Tartari M, Crotti A, Goffredo D, Valenza M, Conti L, Cataudella T, Leavitt BR, Hayden MR, Timmusk T, Rigamonti D, Cattaneo E. 2003. Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat Genet 35:76-83.
-
(2003)
Nat Genet
, vol.35
, pp. 76-83
-
-
Zuccato, C.1
Tartari, M.2
Crotti, A.3
Goffredo, D.4
Valenza, M.5
Conti, L.6
Cataudella, T.7
Leavitt, B.R.8
Hayden, M.R.9
Timmusk, T.10
Rigamonti, D.11
Cattaneo, E.12
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