-
1
-
-
0033954584
-
Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases
-
Alexi T., Borlongan C. V., Faull R. L., Williams C. E., Clark R. G., Gluckman P. D. and Hughes P. E. (2000) Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases. Prog. Neurobiol. 60, 409-470.
-
(2000)
Prog. Neurobiol.
, vol.60
, pp. 409-470
-
-
Alexi, T.1
Borlongan, C.V.2
Faull, R.L.3
Williams, C.E.4
Clark, R.G.5
Gluckman, P.D.6
Hughes, P.E.7
-
2
-
-
0027243086
-
The protooncogene Bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
-
Allsopp T. E., Wyatt S., Paterson H. F. and Davies A. M. (1993) The protooncogene Bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell 73, 295-307.
-
(1993)
Cell
, vol.73
, pp. 295-307
-
-
Allsopp, T.E.1
Wyatt, S.2
Paterson, H.F.3
Davies, A.M.4
-
3
-
-
0029056049
-
Role of Bcl-2 in the brain-derived neurotrophic factor survival response
-
Allsopp T. E., Kiselev S., Wyatt S. and Davies A. M. (1995) Role of Bcl-2 in the brain-derived neurotrophic factor survival response. Eur. J. Neurosci. 7, 1266-1272.
-
(1995)
Eur. J. Neurosci.
, vol.7
, pp. 1266-1272
-
-
Allsopp, T.E.1
Kiselev, S.2
Wyatt, S.3
Davies, A.M.4
-
4
-
-
0028793257
-
Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
-
Ankarcrona M., Dypbukt J. M., Bonfoco E., Zhivotovsky B., Orrenius S., Lipton S. A. and Nicotera P. (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15, 961-973.
-
(1995)
Neuron
, vol.15
, pp. 961-973
-
-
Ankarcrona, M.1
Dypbukt, J.M.2
Bonfoco, E.3
Zhivotovsky, B.4
Orrenius, S.5
Lipton, S.A.6
Nicotera, P.7
-
5
-
-
0035213530
-
Bax and other pro-apoptotic Bcl-2 family 'killer-proteins' and their victim, the mitochondrion
-
Antonsson B. (2001) Bax and other pro-apoptotic Bcl-2 family 'killer-proteins' and their victim, the mitochondrion. Cell Tissue Res. 306, 347-361.
-
(2001)
Cell Tissue Res.
, vol.306
, pp. 347-361
-
-
Antonsson, B.1
-
6
-
-
0028039812
-
Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo
-
Arenas E. and Persson H. (1994) Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo. Nature 367, 368-371.
-
(1994)
Nature
, vol.367
, pp. 368-371
-
-
Arenas, E.1
Persson, H.2
-
7
-
-
16944366580
-
Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice
-
Ayata C. et al. (1997) Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice. J. Neurosci. 17, 6908-6917.
-
(1997)
J. Neurosci.
, vol.17
, pp. 6908-6917
-
-
Ayata, C.1
-
8
-
-
0029153913
-
Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
-
Bonfoco E., Krainc D., Ankarcrona M., Nicotera P. and Lipton S. A. (1995) Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc. Natl Acad. Sci. USA 92, 7162-7166.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 7162-7166
-
-
Bonfoco, E.1
Krainc, D.2
Ankarcrona, M.3
Nicotera, P.4
Lipton, S.A.5
-
9
-
-
0033552047
-
Morphology and compartmental location of cells exhibiting DNA damage after quinolinic acid injections into rat striatum
-
Bordelon Y. M., Mackenzie L. and Chesselet M. F. (1999) Morphology and compartmental location of cells exhibiting DNA damage after quinolinic acid injections into rat striatum. J. Comp. Neurol. 412, 38-50.
-
(1999)
J. Comp. Neurol.
, vol.412
, pp. 38-50
-
-
Bordelon, Y.M.1
Mackenzie, L.2
Chesselet, M.F.3
-
10
-
-
0032443679
-
Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease
-
Canals J. M., Marco S., Checa N., Michels A., Perez-Navarro E., Arenas E. and Alberch J. (1998) Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease. Neurobiol. Dis. 5, 357-364.
-
(1998)
Neurobiol. Dis.
, vol.5
, pp. 357-364
-
-
Canals, J.M.1
Marco, S.2
Checa, N.3
Michels, A.4
Perez-Navarro, E.5
Arenas, E.6
Alberch, J.7
-
11
-
-
0033047042
-
The neurotrophin receptors trkA, trkB and trkC are differentially regulated after excitotoxic lesion in rat striatum
-
Canals J. M., Checa N., Marco S., Michels A., Perez-Navarro E. and Alberch J. (1999) The neurotrophin receptors trkA, trkB and trkC are differentially regulated after excitotoxic lesion in rat striatum. Mol. Brain Res. 69, 242-248.
-
(1999)
Mol. Brain Res.
, vol.69
, pp. 242-248
-
-
Canals, J.M.1
Checa, N.2
Marco, S.3
Michels, A.4
Perez-Navarro, E.5
Alberch, J.6
-
12
-
-
0033587742
-
Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons
-
Chalecka-Franaszek E. and Chuang D. M. (1999) Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons. Proc. Natl Acad. Sci. USA 96, 8745-8750.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 8745-8750
-
-
Chalecka-Franaszek, E.1
Chuang, D.M.2
-
13
-
-
0037762690
-
Neurotrophins and their receptors: A convergence point for many signalling pathways
-
Chao M. V. (2003) Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat. Rev. Neurosci. 4, 299-309.
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, pp. 299-309
-
-
Chao, M.V.1
-
14
-
-
0033525538
-
Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity
-
Chen R. W. and Chuang D. M. (1999) Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity. J. Biol. Chem. 274, 6039-6042.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6039-6042
-
-
Chen, R.W.1
Chuang, D.M.2
-
15
-
-
0034122404
-
Human Bcl-2 protects against AMPA receptor-mediated apoptosis
-
Cheung N. S., Beart P. M., Pascoe C. J., John C. A. and Bernard O. (2000) Human Bcl-2 protects against AMPA receptor-mediated apoptosis. J. Neurochem. 74, 1613-1620.
-
(2000)
J. Neurochem.
, vol.74
, pp. 1613-1620
-
-
Cheung, N.S.1
Beart, P.M.2
Pascoe, C.J.3
John, C.A.4
Bernard, O.5
-
16
-
-
0024093449
-
Glutamate neurotoxicity and diseases of the nervous system
-
Choi D. W. (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634.
-
(1988)
Neuron
, vol.1
, pp. 623-634
-
-
Choi, D.W.1
-
17
-
-
0036716281
-
The Bcl2 family: Regulators of the cellular life-or-death switch
-
Cory S. and Adams J. M. (2002) The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2, 647-656.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
18
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta S. R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y. and Greenberg M. E. (1997) Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91, 231-241.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
19
-
-
0023767138
-
Sparing of cholinergic neurons following quinolinic acid lesions of the rat striatum
-
Davies S. W. and Roberts P. J. (1988) Sparing of cholinergic neurons following quinolinic acid lesions of the rat striatum. Neuroscience 26, 387-393.
-
(1988)
Neuroscience
, vol.26
, pp. 387-393
-
-
Davies, S.W.1
Roberts, P.J.2
-
20
-
-
0030245811
-
BAX is required for neuronal death after trophic factor deprivation and during development
-
Deckwerth T. L., Elliott J. L., Knudson C. M., Johnson E. M., Snider W. D. and Korsmeyer S. J. (1996) BAX is required for neuronal death after trophic factor deprivation and during development. Neuron 17, 401-411.
-
(1996)
Neuron
, vol.17
, pp. 401-411
-
-
Deckwerth, T.L.1
Elliott, J.L.2
Knudson, C.M.3
Johnson, E.M.4
Snider, W.D.5
Korsmeyer, S.J.6
-
21
-
-
0025363346
-
Excitotoxic injury of the neostriatum: A model for Huntington's disease
-
DiFiglia M. (1990) Excitotoxic injury of the neostriatum: a model for Huntington's disease. Trends Neurosci. 13, 286-289.
-
(1990)
Trends Neurosci.
, vol.13
, pp. 286-289
-
-
DiFiglia, M.1
-
22
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase Akt
-
Dudek H., Datta S. R., Franke T. F., Birnbaum M. J., Yao R., Cooper G. M., Segal R. A., Kaplan D. R. and Greenberg M. E. (1997) Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275, 661-665.
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
23
-
-
0034730511
-
Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade
-
Fan M., Goodwin M., Vu T., Brantley-Finley C., Gaarde W. A. and Chambers T. C. (2000) Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade. J. Biol. Chem. 275, 29 980-29 985.
-
(2000)
J. Biol. Chem.
, vol.275
-
-
Fan, M.1
Goodwin, M.2
Vu, T.3
Brantley-Finley, C.4
Gaarde, W.A.5
Chambers, T.C.6
-
24
-
-
0028825108
-
Both apoptosis and necrosis occur following intrastriatal administration of excitotoxins
-
Ferrer I., Martin F., Serrano T., Reiriz J., Perez-Navarro E., Alberch J., Macaya A. and Planas A. M. (1995) Both apoptosis and necrosis occur following intrastriatal administration of excitotoxins. Acta Neuropathol. 90, 504-510.
-
(1995)
Acta Neuropathol.
, vol.90
, pp. 504-510
-
-
Ferrer, I.1
Martin, F.2
Serrano, T.3
Reiriz, J.4
Perez-Navarro, E.5
Alberch, J.6
Macaya, A.7
Planas, A.M.8
-
25
-
-
1642273103
-
Differential involvement of phosphatidylinositol 3-kinase and p42/p44 mitogen activated protein kinase pathways in brain-derived neurotrophic factor-induced trophic effects on cultured striatal neurons
-
Gavalda N., Perez-Navarro E., Gratacos E., Comella J. X. and Alberch J. (2004) Differential involvement of phosphatidylinositol 3-kinase and p42/p44 mitogen activated protein kinase pathways in brain-derived neurotrophic factor-induced trophic effects on cultured striatal neurons. Mol. Cell Neurosci. 25, 460-468.
-
(2004)
Mol. Cell Neurosci.
, vol.25
, pp. 460-468
-
-
Gavalda, N.1
Perez-Navarro, E.2
Gratacos, E.3
Comella, J.X.4
Alberch, J.5
-
26
-
-
0036313772
-
Lithium inhibits aluminum-induced apoptosis in rabbit hippocampus, by preventing cytochrome c translocation, Bcl-2 decrease, Bax elevation and caspase-3 activation
-
Ghribi O., Herman M. M., Spaulding N. K. and Savory J. (2002) Lithium inhibits aluminum-induced apoptosis in rabbit hippocampus, by preventing cytochrome c translocation, Bcl-2 decrease, Bax elevation and caspase-3 activation. J. Neurochem. 82, 137-145.
-
(2002)
J. Neurochem.
, vol.82
, pp. 137-145
-
-
Ghribi, O.1
Herman, M.M.2
Spaulding, N.K.3
Savory, J.4
-
27
-
-
0034811810
-
Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members
-
Gratacos E., Perez-Navarro E., Tolosa E., Arenas E. and Alberch J. (2001) Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members. J. Neurochem. 78, 1287-1296.
-
(2001)
J. Neurochem.
, vol.78
, pp. 1287-1296
-
-
Gratacos, E.1
Perez-Navarro, E.2
Tolosa, E.3
Arenas, E.4
Alberch, J.5
-
28
-
-
0029964257
-
Taxol induces bcl-2 phosphorylation and death of prostate cancer cells
-
Haldar S., Chintapalli J. and Croce C. M. (1996) Taxol induces bcl-2 phosphorylation and death of prostate cancer cells. Cancer Res. 56, 1253-1255.
-
(1996)
Cancer Res.
, vol.56
, pp. 1253-1255
-
-
Haldar, S.1
Chintapalli, J.2
Croce, C.M.3
-
29
-
-
0033529638
-
Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase
-
Hetman M., Kanning K., Cavanaugh J. E. and Xia Z. (1999) Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. J. Biol. Chem. 274, 22 569-22 580.
-
(1999)
J. Biol. Chem.
, vol.274
-
-
Hetman, M.1
Kanning, K.2
Cavanaugh, J.E.3
Xia, Z.4
-
30
-
-
0030272509
-
Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation
-
Hughes P. E., Alexi T., Yoshida T., Schreiber S. S. and Knusel B. (1996) Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation. Neuroscience 74, 1143-1160.
-
(1996)
Neuroscience
, vol.74
, pp. 1143-1160
-
-
Hughes, P.E.1
Alexi, T.2
Yoshida, T.3
Schreiber, S.S.4
Knusel, B.5
-
31
-
-
0030461002
-
A bcl-2 expressing viral vector protects cortical neurons from excitotoxicity even when administered several hours after the toxic insult
-
Jia W. W., Wang Y., Qiang D., Tufaro F., Remington R. and Cynader M. (1996) A bcl-2 expressing viral vector protects cortical neurons from excitotoxicity even when administered several hours after the toxic insult. Mol. Brain Res. 42, 350-353.
-
(1996)
Mol. Brain Res.
, vol.42
, pp. 350-353
-
-
Jia, W.W.1
Wang, Y.2
Qiang, D.3
Tufaro, F.4
Remington, R.5
Cynader, M.6
-
32
-
-
0037104660
-
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
-
Kim A. H., Yano H., Cho H., Meyer D., Monks B., Margolis B., Birnbaum M. J. and Chao M. V. (2002) Akt1 regulates a JNK scaffold during excitotoxic apoptosis. Neuron 35, 697-709.
-
(2002)
Neuron
, vol.35
, pp. 697-709
-
-
Kim, A.H.1
Yano, H.2
Cho, H.3
Meyer, D.4
Monks, B.5
Margolis, B.6
Birnbaum, M.J.7
Chao, M.V.8
-
33
-
-
0028973310
-
Upregulation of bax protein levels in neurons following cerebral ischemia
-
Krajewski S., Mai J. K., Krajewska M., Sikorska M., Mossakowski M. J. and Reed J. C. (1995) Upregulation of bax protein levels in neurons following cerebral ischemia. J. Neurosci. 15, 6364-6376.
-
(1995)
J. Neurosci.
, vol.15
, pp. 6364-6376
-
-
Krajewski, S.1
Mai, J.K.2
Krajewska, M.3
Sikorska, M.4
Mossakowski, M.J.5
Reed, J.C.6
-
34
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P., Nijhawan D., Budihardjo I., Srinivasula S. M., Ahmad M., Alnemri E. S. and Wang X. D. (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.D.7
-
35
-
-
0036320888
-
Rapid subcellular redistribution of Bax precedes caspase-3 and endonuclease activation during excitotoxic neuronal apoptosis in rat brain
-
Lok J. and Martin L. J. (2002) Rapid subcellular redistribution of Bax precedes caspase-3 and endonuclease activation during excitotoxic neuronal apoptosis in rat brain. J. Neurotrauma 19, 815-828.
-
(2002)
J. Neurotrauma
, vol.19
, pp. 815-828
-
-
Lok, J.1
Martin, L.J.2
-
36
-
-
0141482027
-
Akt as a mediator of cell death
-
Luo H. R., Hattori H., Hossain M. A., Hester L., Huang Y., Lee-Kwon W., Donowitz M., Nagata E. and Snyder S. H. (2003) Akt as a mediator of cell death. Proc. Natl Acad. Sci. USA 30, 11 712-11 717.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.30
-
-
Luo, H.R.1
Hattori, H.2
Hossain, M.A.3
Hester, L.4
Huang, Y.5
Lee-Kwon, W.6
Donowitz, M.7
Nagata, E.8
Snyder, S.H.9
-
37
-
-
0141560577
-
Cyclosporin A and Bcl-2 do not inhibit quinolinic acid-induced striatal excitotoxicity in rodents
-
Maciel E. N., Kaminski Schierle G. S., Hansson O., Brundin P. and Castilho R. F. (2003) Cyclosporin A and Bcl-2 do not inhibit quinolinic acid-induced striatal excitotoxicity in rodents. Exp. Neurol. 183, 430-437.
-
(2003)
Exp. Neurol.
, vol.183
, pp. 430-437
-
-
Maciel, E.N.1
Kaminski Schierle, G.S.2
Hansson, O.3
Brundin, P.4
Castilho, R.F.5
-
38
-
-
0036218670
-
Excitatory amino acids differentially regulate the expression of GDNF, neurturin, and their receptors in the adult rat striatum
-
Marco S., Canudas A. M., Canals J. M., Gavalda N., Perez-Navarro E. and Alberch J. (2002) Excitatory amino acids differentially regulate the expression of GDNF, neurturin, and their receptors in the adult rat striatum. Exp. Neurol. 174, 243-252.
-
(2002)
Exp. Neurol.
, vol.174
, pp. 243-252
-
-
Marco, S.1
Canudas, A.M.2
Canals, J.M.3
Gavalda, N.4
Perez-Navarro, E.5
Alberch, J.6
-
39
-
-
15644381250
-
Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress- activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1
-
Maundrell K., Antonsson B., Magnenat E. et al. (1997) Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1. J. Biol. Chem. 272, 25 238-25 242.
-
(1997)
J. Biol. Chem.
, vol.272
-
-
Maundrell, K.1
Antonsson, B.2
Magnenat, E.3
-
40
-
-
0032909368
-
Activity and expression of JNK1, p38 and ERK kinases, c-Jun N-terminal phosphorylation, and c-jun promoter binding in the adult rat brain following kainate-induced seizures
-
Mielke K., Brecht S., Dorst A. and Herdegen T. (1999) Activity and expression of JNK1, p38 and ERK kinases, c-Jun N-terminal phosphorylation, and c-jun promoter binding in the adult rat brain following kainate-induced seizures. Neuroscience 91, 471-483.
-
(1999)
Neuroscience
, vol.91
, pp. 471-483
-
-
Mielke, K.1
Brecht, S.2
Dorst, A.3
Herdegen, T.4
-
41
-
-
0030011451
-
Neurotrophins promote the survival and development of neurons in the cerebellum of hypothyroid rats in vivo
-
Neveu I. and Arenas E. (1996) Neurotrophins promote the survival and development of neurons in the cerebellum of hypothyroid rats in vivo. J. Cell Biol. 133, 631-646.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 631-646
-
-
Neveu, I.1
Arenas, E.2
-
42
-
-
0032510758
-
Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
-
Offen D., Beart P. M., Cheung N. S., Pascoe C. J., Hochman A., Gorodin S., Melamed E., Bernard R. and Bernard O. (1998) Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Proc. Natl Acad. Sci. USA 95, 5789-5794.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 5789-5794
-
-
Offen, D.1
Beart, P.M.2
Cheung, N.S.3
Pascoe, C.J.4
Hochman, A.5
Gorodin, S.6
Melamed, E.7
Bernard, R.8
Bernard, O.9
-
43
-
-
0032476032
-
Insulin-like growth factor-I inhibits the stress-activated protein kinase/c-Jun N-terminal kinase
-
Okubo Y., Blakesley V. A., Stannard B., Gutkind S. and Le Roith D. (1998) Insulin-like growth factor-I inhibits the stress-activated protein kinase/c-Jun N-terminal kinase. J. Biol. Chem. 273, 25 961-25 966.
-
(1998)
J. Biol. Chem.
, vol.273
-
-
Okubo, Y.1
Blakesley, V.A.2
Stannard, B.3
Gutkind, S.4
Le Roith, D.5
-
44
-
-
0035369840
-
Trk receptors: Mediators of neurotrophin action
-
Patapoutian A. and Reichardt L. F. (2001) Trk receptors: mediators of neurotrophin action. Curr. Opin. Neurobiol. 11, 272-280.
-
(2001)
Curr. Opin. Neurobiol.
, vol.11
, pp. 272-280
-
-
Patapoutian, A.1
Reichardt, L.F.2
-
45
-
-
0345517258
-
Brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4/5 differentially regulate the phenotype and prevent degenerative changes in striatal projection neurons after excitotoxicity in vivo
-
Perez-Navarro E., Alberch J., Neveu I. and Arenas E. (1999) Brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4/5 differentially regulate the phenotype and prevent degenerative changes in striatal projection neurons after excitotoxicity in vivo. Neuroscience 91, 1257-1264.
-
(1999)
Neuroscience
, vol.91
, pp. 1257-1264
-
-
Perez-Navarro, E.1
Alberch, J.2
Neveu, I.3
Arenas, E.4
-
46
-
-
0033789409
-
Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease
-
Perez-Navarro E., Canudas A. M., Akerund P., Alberch J. and Arenas E. (2000a) Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease. J. Neurochem. 75, 2190-2199.
-
(2000)
J. Neurochem.
, vol.75
, pp. 2190-2199
-
-
Perez-Navarro, E.1
Canudas, A.M.2
Akerund, P.3
Alberch, J.4
Arenas, E.5
-
47
-
-
0343091556
-
Neurturin protects striatal projection neurons but not interneurons in a rat model of Huntington's disease
-
Perez-Navarro E., Akerud P., Marco S., Canals J. M., Tolosa E., Arenas E. and Alberch J. (2000b) Neurturin protects striatal projection neurons but not interneurons in a rat model of Huntington's disease. Neuroscience 98, 89-96.
-
(2000)
Neuroscience
, vol.98
, pp. 89-96
-
-
Perez-Navarro, E.1
Akerud, P.2
Marco, S.3
Canals, J.M.4
Tolosa, E.5
Arenas, E.6
Alberch, J.7
-
48
-
-
0030181799
-
Stimulation of N-methyl-D-aspartate receptors induces apoptosis in rat brain
-
Qin Z. H., Wang Y. and Chase T. N. (1996) Stimulation of N-methyl-D-aspartate receptors induces apoptosis in rat brain. Brain Res. 725, 166-176.
-
(1996)
Brain Res.
, vol.725
, pp. 166-176
-
-
Qin, Z.H.1
Wang, Y.2
Chase, T.N.3
-
49
-
-
0033579301
-
'Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons
-
Riccio A., Ahn S., Davenport C. M., Blendy J. A. and Ginty D. D. (1999) 'Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. Science 286, 2358-2361.
-
(1999)
Science
, vol.286
, pp. 2358-2361
-
-
Riccio, A.1
Ahn, S.2
Davenport, C.M.3
Blendy, J.A.4
Ginty, D.D.5
-
50
-
-
0034764108
-
Analysis of the NF-kappa B and PI 3-kinase/Akt survival pathways in nerve growth factor-dependent neurons
-
Sarmiere P. D. and Freeman R. S. (2001) Analysis of the NF-kappa B and PI 3-kinase/Akt survival pathways in nerve growth factor-dependent neurons. Mol. Cell. Neurosci. 18, 320-331.
-
(2001)
Mol. Cell. Neurosci.
, vol.18
, pp. 320-331
-
-
Sarmiere, P.D.1
Freeman, R.S.2
-
51
-
-
0032511838
-
Decreased expression of bcl-2 and bcl-x mRNA coincides with apoptosis following intracerebral administration of 3-nitropropionic acid
-
Sato S., Gobbel G. T., Honkaniemi J., Li Y., Kondo T., Murakami K., Sato M., Copin J. C., Sharp F. R. and Chan P. H. (1998) Decreased expression of bcl-2 and bcl-x mRNA coincides with apoptosis following intracerebral administration of 3-nitropropionic acid. Brain Res. 808, 56-64.
-
(1998)
Brain Res.
, vol.808
, pp. 56-64
-
-
Sato, S.1
Gobbel, G.T.2
Honkaniemi, J.3
Li, Y.4
Kondo, T.5
Murakami, K.6
Sato, M.7
Copin, J.C.8
Sharp, F.R.9
Chan, P.H.10
-
52
-
-
0033962594
-
Neuroprotective mechanism of glial cell line-derived neurotrophic factor in mesencephalic neurons
-
Sawada H., Ibi M., Kihara T., Urushitani M., Nakanishi M., Akaike A. and Shimohama S. (2000) Neuroprotective mechanism of glial cell line-derived neurotrophic factor in mesencephalic neurons. J. Neurochem. 74, 1175-1184.
-
(2000)
J. Neurochem.
, vol.74
, pp. 1175-1184
-
-
Sawada, H.1
Ibi, M.2
Kihara, T.3
Urushitani, M.4
Nakanishi, M.5
Akaike, A.6
Shimohama, S.7
-
53
-
-
0033811469
-
Intravenous brain-derived neurotrophic factor reduces infarct size and counterregulates Bax and Bcl-2 expression after temporary focal cerebral ischemia
-
Schabitz W. R., Sommer C., Zoder W., Kiessling M., Schwaninger M. and Schwab S. (2000) Intravenous brain-derived neurotrophic factor reduces infarct size and counterregulates Bax and Bcl-2 expression after temporary focal cerebral ischemia. Stroke 31, 2212-2217.
-
(2000)
Stroke
, vol.31
, pp. 2212-2217
-
-
Schabitz, W.R.1
Sommer, C.2
Zoder, W.3
Kiessling, M.4
Schwaninger, M.5
Schwab, S.6
-
54
-
-
0030901162
-
Fluoro-Jade: A novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
-
Schmued L. C., Albertson C. and Slikker W. (1997) Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res. 751, 37-46.
-
(1997)
Brain Res.
, vol.751
, pp. 37-46
-
-
Schmued, L.C.1
Albertson, C.2
Slikker, W.3
-
55
-
-
0030957325
-
Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons
-
Schwarzschild M. A., Cole R. L. and Hyman S. E. (1997) Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons. J. Neurosci. 17, 3455-3466.
-
(1997)
J. Neurosci.
, vol.17
, pp. 3455-3466
-
-
Schwarzschild, M.A.1
Cole, R.L.2
Hyman, S.E.3
-
56
-
-
0030710188
-
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway
-
Skorski T., Bellacosa A., Nieborowska-Skorska M. et al. (1997) Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway. EMBO J. 16, 6151-6161.
-
(1997)
EMBO J.
, vol.16
, pp. 6151-6161
-
-
Skorski, T.1
Bellacosa, A.2
Nieborowska-Skorska, M.3
-
57
-
-
0032528139
-
Roles of Bcl-2 and caspases in hypoxia-induced neuronal cell death: A possible neuroprotective mechanism of peptide growth factors
-
Tamatani M., Ogawa S. and Tohyama M. (1998) Roles of Bcl-2 and caspases in hypoxia-induced neuronal cell death: a possible neuroprotective mechanism of peptide growth factors. Mol. Brain Res. 58, 27-39.
-
(1998)
Mol. Brain Res.
, vol.58
, pp. 27-39
-
-
Tamatani, M.1
Ogawa, S.2
Tohyama, M.3
-
58
-
-
0031815544
-
Role of caspases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons
-
Tenneti L., D'Emilia D. M., Troy C. M. and Lipton S. A. (1998) Role of caspases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons. J. Neurochem. 71, 946-959.
-
(1998)
J. Neurochem.
, vol.71
, pp. 946-959
-
-
Tenneti, L.1
D'Emilia, D.M.2
Troy, C.M.3
Lipton, S.A.4
-
59
-
-
0032864021
-
Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival
-
Vaillant A. R., Mazzoni I., Tudan C., Boudreau M., Kaplan D. R. and Miller F. D. (1999) Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival. J. Cell Biol. 146, 955-966.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 955-966
-
-
Vaillant, A.R.1
Mazzoni, I.2
Tudan, C.3
Boudreau, M.4
Kaplan, D.R.5
Miller, F.D.6
-
60
-
-
0035956874
-
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
-
Vila M., Jackson-Lewis V., Vukosavic S., Djaldetti R., Liberatore G., Offen D., Korsmeyer S. J. and Przedborski S. (2001) Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine mouse model of Parkinson's disease. Proc. Natl Acad. Sci. USA 98, 2837-2842.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 2837-2842
-
-
Vila, M.1
Jackson-Lewis, V.2
Vukosavic, S.3
Djaldetti, R.4
Liberatore, G.5
Offen, D.6
Korsmeyer, S.J.7
Przedborski, S.8
-
61
-
-
0035960005
-
Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease
-
Wei H., Qin Z. H., Senatorov V. V., Wei W., Wang Y., Qian Y. and Chuang D. M. (2002) Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease. Neuroscience 106, 603-612.
-
(2002)
Neuroscience
, vol.106
, pp. 603-612
-
-
Wei, H.1
Qin, Z.H.2
Senatorov, V.V.3
Wei, W.4
Wang, Y.5
Qian, Y.6
Chuang, D.M.7
-
62
-
-
0242391823
-
Comparison of inhibitory effects of brain-derived neurotrophic factor and insulin-like growth factor on low potassium-induced apoptosis and activation of p38 MAPK and c-Jun in cultured cerebellar granule neurons
-
Yamagishi S., Matsumoto T., Yokomaku D., Hatanaka H., Shimoke K., Yamada M. and Ikeuchi T. (2003) Comparison of inhibitory effects of brain-derived neurotrophic factor and insulin-like growth factor on low potassium-induced apoptosis and activation of p38 MAPK and c-Jun in cultured cerebellar granule neurons. Mol. Brain Res. 119, 184-191.
-
(2003)
Mol. Brain Res.
, vol.119
, pp. 184-191
-
-
Yamagishi, S.1
Matsumoto, T.2
Yokomaku, D.3
Hatanaka, H.4
Shimoke, K.5
Yamada, M.6
Ikeuchi, T.7
-
63
-
-
0030780804
-
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
-
Yang D. D., Kuan C. Y., Whitmarsh A. J., Rincon M., Zheng T. S., Davis R. J., Rakic P. and Flavell R. A. (1997) Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 389, 865-870.
-
(1997)
Nature
, vol.389
, pp. 865-870
-
-
Yang, D.D.1
Kuan, C.Y.2
Whitmarsh, A.J.3
Rincon, M.4
Zheng, T.S.5
Davis, R.J.6
Rakic, P.7
Flavell, R.A.8
-
64
-
-
0027525104
-
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
-
Yuan J., Shaham S., Ledoux S., Ellis H. M. and Horvitz H. R. (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell 75, 641-652.
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledoux, S.3
Ellis, H.M.4
Horvitz, H.R.5
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