Analysis of alteration of p75NTR processing and signalling by PS2 mutation and γ-secretase inhibition

Neurobiology of Disease

Volumn 27, Issue 3, 2007, Pages 258-264

  Ito, Yoshio ^a   Ishii, Azusa ^a   Passmore, A Peter ^a   McIlroy, Stephen P ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Alzheimer's disease; Neurotrophin pathway; p75NTR; Presenilin; RhoA; TrkA

Indexed keywords

GAMMA SECRETASE; NEUROTROPHIN RECEPTOR; PRESENILIN 2; PROTEIN P75; PROTEIN PS2; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; NERVE GROWTH FACTOR RECEPTOR; SECRETASE; TRAF4 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 4; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; DRUG ANTAGONISM; GENETICS; IMMUNOBLOTTING; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AMYLOID PRECURSOR PROTEIN SECRETASES; CELL LINE, TUMOR; HUMANS; IMMUNOBLOTTING; MUTATION; PRESENILIN-2; RECEPTOR, NERVE GROWTH FACTOR; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 4;

EID: 34548316144     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2007.05.002     Document Type: Article

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