메뉴 건너뛰기




Volumn 583, Issue 2, 2007, Pages 425-430

Why some of us get fat and what we can do about it

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; ALPHA INTERMEDIN; FATTY ACID; GHRELIN; INSULIN; KETONE; LACTIC ACID; LEPTIN; LIPID; MELANIN CONCENTRATING HORMONE; NEUROPEPTIDE; NEUROPEPTIDE Y; NEUROTRANSMITTER; OREXIN; PROOPIOMELANOCORTIN;

EID: 34548309448     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.135434     Document Type: Conference Paper
Times cited : (29)

References (63)
  • 1
    • 0024160952 scopus 로고
    • MSG effects on β-endorphin and α-MSH in the hypothalamus and caudal medulla
    • Alessi NE, Quinlan P & Khachaturian H (1988). MSG effects on β-endorphin and α-MSH in the hypothalamus and caudal medulla. Peptides 9, 689-695.
    • (1988) Peptides , vol.9 , pp. 689-695
    • Alessi, N.E.1    Quinlan, P.2    Khachaturian, H.3
  • 2
    • 0001643038 scopus 로고
    • Activity of single neurons in the hypothalamus feeding centers: Effect of glucose
    • Anand BK, Chhina GS, Sharma KN, Dua S & Singh B (1964). Activity of single neurons in the hypothalamus feeding centers: Effect of glucose. Am J Physiol 207, 1146-1154.
    • (1964) Am J Physiol , vol.207 , pp. 1146-1154
    • Anand, B.K.1    Chhina, G.S.2    Sharma, K.N.3    Dua, S.4    Singh, B.5
  • 3
    • 0036627597 scopus 로고    scopus 로고
    • Multiple neural systems controlling food intake and body weight
    • Berthoud HR (2002). Multiple neural systems controlling food intake and body weight. Neurosci Biobehav Rev 26, 393-428.
    • (2002) Neurosci Biobehav Rev , vol.26 , pp. 393-428
    • Berthoud, H.R.1
  • 4
    • 0025331424 scopus 로고
    • Relative contribution of glycogenolysis and gluconeogenesis to basal, glucagon- and nerve stimulation-dependent glucose output in the perfused liver from fed and fasted rats
    • Beuers U & Jungermann K (1990). Relative contribution of glycogenolysis and gluconeogenesis to basal, glucagon- and nerve stimulation-dependent glucose output in the perfused liver from fed and fasted rats. Biochem Int 21, 405-415.
    • (1990) Biochem Int , vol.21 , pp. 405-415
    • Beuers, U.1    Jungermann, K.2
  • 6
    • 1642349297 scopus 로고    scopus 로고
    • Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice
    • Bouret SG, Draper SJ & Simerly RB (2004). Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice. J Neurosci 24, 2797-2805.
    • (2004) J Neurosci , vol.24 , pp. 2797-2805
    • Bouret, S.G.1    Draper, S.J.2    Simerly, R.B.3
  • 7
    • 0032576536 scopus 로고    scopus 로고
    • Hypocretin/orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and agouti gene-related protein systems
    • Broberger C, De Lecea L, Sutcliffe JG & Hokfelt T (1998). Hypocretin/ orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and agouti gene-related protein systems. J Comp Neurol 402, 460-474.
    • (1998) J Comp Neurol , vol.402 , pp. 460-474
    • Broberger, C.1    De Lecea, L.2    Sutcliffe, J.G.3    Hokfelt, T.4
  • 8
    • 0022341166 scopus 로고
    • Neuropeptide Y stimulates feeding but inhibits sexual behavior in rats
    • Clark JT, Kalra PS & Kalra SP (1985). Neuropeptide Y stimulates feeding but inhibits sexual behavior in rats. Endocrinology 117, 2435-2442.
    • (1985) Endocrinology , vol.117 , pp. 2435-2442
    • Clark, J.T.1    Kalra, P.S.2    Kalra, S.P.3
  • 10
    • 0022491171 scopus 로고
    • Energy expenditure in rats with diet-induced obesity
    • Corbett SW, Stern JS & Keesey RE (1986). Energy expenditure in rats with diet-induced obesity. Am J Clin Nutr 44, 173-180.
    • (1986) Am J Clin Nutr , vol.44 , pp. 173-180
    • Corbett, S.W.1    Stern, J.S.2    Keesey, R.E.3
  • 11
    • 0242583963 scopus 로고    scopus 로고
    • Hypothalamic melanocortin neurons integrate signals of energy state
    • Cowley MA (2003). Hypothalamic melanocortin neurons integrate signals of energy state. Eur J Pharmacol 480, 3-11.
    • (2003) Eur J Pharmacol , vol.480 , pp. 3-11
    • Cowley, M.A.1
  • 14
    • 0033931981 scopus 로고    scopus 로고
    • Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
    • El-Haschimi K, Pierroz DD, Hileman SM, Bjorbaek C & Flier JS (2000). Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. J Clin Invest 105, 1827-1832.
    • (2000) J Clin Invest , vol.105 , pp. 1827-1832
    • El-Haschimi, K.1    Pierroz, D.D.2    Hileman, S.M.3    Bjorbaek, C.4    Flier, J.S.5
  • 15
    • 34248172348 scopus 로고    scopus 로고
    • Maternal obesity increases hypothalamic leptin receptor expression and sensitivity in juvenile obesity-prone rats
    • Gorski JN, Dunn-Meynell AA & Levin BE (2007). Maternal obesity increases hypothalamic leptin receptor expression and sensitivity in juvenile obesity-prone rats. Am J Physiol Regul Integr Comp Physiol 292, R1782-R1791.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292
    • Gorski, J.N.1    Dunn-Meynell, A.A.2    Levin, B.E.3
  • 16
    • 28444434973 scopus 로고    scopus 로고
    • Effects of cross fostering on body weight, adiposity and insulin sensitivity in selectively bred obesity-prone and resistant rats
    • Gorski J & Levin BE (2004). Effects of cross fostering on body weight, adiposity and insulin sensitivity in selectively bred obesity-prone and resistant rats. Obes Res 12, A103.
    • (2004) Obes Res , vol.12
    • Gorski, J.1    Levin, B.E.2
  • 17
    • 0344488068 scopus 로고    scopus 로고
    • Activation of melanocortin-4 receptors enhances thermogenic sympathetic nerve activity to brown adipose tissue
    • Haynes WG, Morgan DA, Djalali A & Mark AL (1998). Activation of melanocortin-4 receptors enhances thermogenic sympathetic nerve activity to brown adipose tissue. Hypertension 32, 620A.
    • (1998) Hypertension , vol.32
    • Haynes, W.G.1    Morgan, D.A.2    Djalali, A.3    Mark, A.L.4
  • 19
    • 0020641377 scopus 로고
    • Effects of a high-fat diet on energy intake and expenditure in rats
    • Hill JO, Fried SK & Digirolamo M (1983). Effects of a high-fat diet on energy intake and expenditure in rats. Life Sci 33, 141-149.
    • (1983) Life Sci , vol.33 , pp. 141-149
    • Hill, J.O.1    Fried, S.K.2    Digirolamo, M.3
  • 21
    • 33845903638 scopus 로고    scopus 로고
    • Altered hypothalamic leptin, insulin and melanocortin binding associated with moderate fat diet and predisposition to obesity
    • Irani BG, Dunn-Meynell AA & Levin BE (2007). Altered hypothalamic leptin, insulin and melanocortin binding associated with moderate fat diet and predisposition to obesity. Endocrinology 148, 310-316.
    • (2007) Endocrinology , vol.148 , pp. 310-316
    • Irani, B.G.1    Dunn-Meynell, A.A.2    Levin, B.E.3
  • 22
    • 0018124360 scopus 로고
    • Food intake and utilization in lateral hypothalamically lesioned rats
    • Keesey RE, Boyle PC & Storlien LH (1978). Food intake and utilization in lateral hypothalamically lesioned rats. Physiol Behav 21, 265-268.
    • (1978) Physiol Behav , vol.21 , pp. 265-268
    • Keesey, R.E.1    Boyle, P.C.2    Storlien, L.H.3
  • 23
    • 0000348081 scopus 로고
    • The role of depot fat in the hypothalamic control of food intake in the rat
    • Kennedy GC (1953). The role of depot fat in the hypothalamic control of food intake in the rat. Proc R Soc Lond B Biol Sci 611, 221-235.
    • (1953) Proc R Soc Lond B Biol Sci , vol.611 , pp. 221-235
    • Kennedy, G.C.1
  • 24
    • 0034036671 scopus 로고    scopus 로고
    • A case-control study of successful maintenance of a substantial weight loss: Individuals who lost weight through surgery versus those who lost weight through non-surgical means
    • Klem ML, Wing RR, Chang CC, Lang W, McGuire MT, Sugerman HJ, Hutchison SL, Makovich AL & Hill JO (2000). A case-control study of successful maintenance of a substantial weight loss: Individuals who lost weight through surgery versus those who lost weight through non-surgical means. Internat J Obes Relat Metab Disord 24, 573-579.
    • (2000) Internat J Obes Relat Metab Disord , vol.24 , pp. 573-579
    • Klem, M.L.1    Wing, R.R.2    Chang, C.C.3    Lang, W.4    McGuire, M.T.5    Sugerman, H.J.6    Hutchison, S.L.7    Makovich, A.L.8    Hill, J.O.9
  • 25
    • 0035100001 scopus 로고    scopus 로고
    • Melanin-concentrating hormone receptor is a target of leptin action in the mouse brain
    • Kokkotou EG, Tritos NA, Mastaitis JW, Slieker L & Maratos-Flier E (2001). Melanin-concentrating hormone receptor is a target of leptin action in the mouse brain. Endocrinol 142, 680-686.
    • (2001) Endocrinol , vol.142 , pp. 680-686
    • Kokkotou, E.G.1    Tritos, N.A.2    Mastaitis, J.W.3    Slieker, L.4    Maratos-Flier, E.5
  • 26
    • 33646198037 scopus 로고    scopus 로고
    • Management of overweight and obesity in adults: Behavioral intervention for long-term weight loss and maintenance
    • Lang A & Froelicher ES (2006). Management of overweight and obesity in adults: Behavioral intervention for long-term weight loss and maintenance. Eur J Cardiovasc Nurs 5, 102-114.
    • (2006) Eur J Cardiovasc Nurs , vol.5 , pp. 102-114
    • Lang, A.1    Froelicher, E.S.2
  • 27
    • 0021324335 scopus 로고
    • Diminished energy requirements in reduced-obese patients
    • Leibel RL & Hirsch J (1984). Diminished energy requirements in reduced-obese patients. Metabolism 33, 164-170.
    • (1984) Metabolism , vol.33 , pp. 164-170
    • Leibel, R.L.1    Hirsch, J.2
  • 28
    • 0028959193 scopus 로고
    • Changes in energy expenditure resulting from altered body weight
    • Leibel RL, Rosenbaum M & Hirsch J (1995). Changes in energy expenditure resulting from altered body weight. N Engl J Med 332, 621-628.
    • (1995) N Engl J Med , vol.332 , pp. 621-628
    • Leibel, R.L.1    Rosenbaum, M.2    Hirsch, J.3
  • 29
    • 33749319936 scopus 로고    scopus 로고
    • Orexins: Neuropeptides for all seasons and functions
    • Levin BE (2006). Orexins: Neuropeptides for all seasons and functions. Am J Physiol Regul Integr Comp Physiol 291, R885-R888.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.291
    • Levin, B.E.1
  • 30
    • 0034029704 scopus 로고    scopus 로고
    • Defense of body weight against chronic caloric restriction in obesity-prone and -resistant rats
    • Levin BE & Dunn-Meynell AA (2000). Defense of body weight against chronic caloric restriction in obesity-prone and -resistant rats. Am J Physiol Regul Integr Comp Physiol 278, R231-R237.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.278
    • Levin, B.E.1    Dunn-Meynell, A.A.2
  • 31
    • 0036080699 scopus 로고    scopus 로고
    • Defense of body weight depends on dietary composition and palatability in rats with diet-induced obesity
    • Levin BE & Dunn-Meynell AA (2002 a). Defense of body weight depends on dietary composition and palatability in rats with diet-induced obesity. Am J Physiol Regul Integr Comp Physiol 282, R46-R54.
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.282
    • Levin, B.E.1    Dunn-Meynell, A.A.2
  • 32
    • 0036838623 scopus 로고    scopus 로고
    • Maternal obesity alters adiposity and monoamine function in genetically predisposed offspring
    • Levin BE & Dunn-Meynell AA (2002 b). Maternal obesity alters adiposity and monoamine function in genetically predisposed offspring. Am J Physiol Regul Integr Comp Physiol 283, R1087-R1093.
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.283
    • Levin, B.E.1    Dunn-Meynell, A.A.2
  • 35
    • 0347988175 scopus 로고    scopus 로고
    • Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling prior to obesity onset
    • Levin BE, Dunn-Meynell AA & Banks WA (2004 a). Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling prior to obesity onset. Am J Physiol Regul Integr Comp Physiol 286, R143-R150.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Levin, B.E.1    Dunn-Meynell, A.A.2    Banks, W.A.3
  • 37
    • 0031738244 scopus 로고    scopus 로고
    • Gestational obesity accentuates obesity in obesity-prone progeny
    • Levin BE & Govek E (1998). Gestational obesity accentuates obesity in obesity-prone progeny. Am J Physiol Regul Integr Comp Physiol 275, R1374-R1379.
    • (1998) Am J Physiol Regul Integr Comp Physiol , vol.275
    • Levin, B.E.1    Govek, E.2
  • 38
    • 33845534242 scopus 로고    scopus 로고
    • Role of neuronal glucosensing in the regulation of energy homeostasis
    • Levin BE, Kang L, Sanders NM & Dunn-Meynell AA (2006). Role of neuronal glucosensing in the regulation of energy homeostasis. Diabetes 55 (Suppl. 2), S122-S130.
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 2
    • Levin, B.E.1    Kang, L.2    Sanders, N.M.3    Dunn-Meynell, A.A.4
  • 39
    • 0031958083 scopus 로고    scopus 로고
    • Defense of differing body weight set-points in diet-induced obese and resistant rats
    • Levin BE & Keesey RE (1998). Defense of differing body weight set-points in diet-induced obese and resistant rats. Am J Physiol Regul Integr Comp Physiol 274, R412-R419.
    • (1998) Am J Physiol Regul Integr Comp Physiol , vol.274
    • Levin, B.E.1    Keesey, R.E.2
  • 43
    • 0034268123 scopus 로고    scopus 로고
    • Differential expression of leptin receptor in high- and low-fat-fed Osborne-Mendel and S5B/Pl rats
    • Madiehe AM, Schaffhauser AO, Braymer DH, Bray GA & York DA (2000). Differential expression of leptin receptor in high- and low-fat-fed Osborne-Mendel and S5B/Pl rats. Obes Res 8, 467-474.
    • (2000) Obes Res , vol.8 , pp. 467-474
    • Madiehe, A.M.1    Schaffhauser, A.O.2    Braymer, D.H.3    Bray, G.A.4    York, D.A.5
  • 46
    • 0037329602 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in leptin-induced fatty acid oxidation in muscle
    • Minokoshi Y & Kahn BB (2003). Role of AMP-activated protein kinase in leptin-induced fatty acid oxidation in muscle. Biochem Soc Trans 31, 196-201.
    • (2003) Biochem Soc Trans , vol.31 , pp. 196-201
    • Minokoshi, Y.1    Kahn, B.B.2
  • 47
    • 0033515710 scopus 로고    scopus 로고
    • Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y
    • Muroya S, Yada T, Shioda S & Takigawa M (1999). Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y. Neurosci Lett 264, 113-116.
    • (1999) Neurosci Lett , vol.264 , pp. 113-116
    • Muroya, S.1    Yada, T.2    Shioda, S.3    Takigawa, M.4
  • 49
    • 0030764741 scopus 로고    scopus 로고
    • Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
    • Ollmann MM, Wilson BD, Yang YK, Kerns JA, Chen Y, Gantz I & Barsh GS (1997). Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278, 135-138.
    • (1997) Science , vol.278 , pp. 135-138
    • Ollmann, M.M.1    Wilson, B.D.2    Yang, Y.K.3    Kerns, J.A.4    Chen, Y.5    Gantz, I.6    Barsh, G.S.7
  • 50
    • 0000293983 scopus 로고
    • Reciprocal activities of the ventromedial and lateral hypothalamic area of cats
    • Oomura Y, Kimura K, Ooyama H, Maeo T, Iki M & Kuniyoshi N (1964). Reciprocal activities of the ventromedial and lateral hypothalamic area of cats. Science 143, 484-485.
    • (1964) Science , vol.143 , pp. 484-485
    • Oomura, Y.1    Kimura, K.2    Ooyama, H.3    Maeo, T.4    Iki, M.5    Kuniyoshi, N.6
  • 51
    • 0033787384 scopus 로고    scopus 로고
    • Maternal environment and genotype interact to establish diabesity in mice
    • Reifsnyder PC, Churchill G & Leiter EH (2000). Maternal environment and genotype interact to establish diabesity in mice. Genome Res 10, 1568-1578.
    • (2000) Genome Res , vol.10 , pp. 1568-1578
    • Reifsnyder, P.C.1    Churchill, G.2    Leiter, E.H.3
  • 52
    • 0033126914 scopus 로고    scopus 로고
    • Isoproterenol decreases leptin expression in adipose tissue of obese humans
    • Ricci MR & Fried SK (1999). Isoproterenol decreases leptin expression in adipose tissue of obese humans. Obes Res 7, 233-240.
    • (1999) Obes Res , vol.7 , pp. 233-240
    • Ricci, M.R.1    Fried, S.K.2
  • 54
    • 0036093071 scopus 로고    scopus 로고
    • Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones
    • Rosenbaum M, Murphy EM, Heymsfield SB, Matthews DE & Leibel RL (2002). Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones. J Clin Endocrinol Metab 87, 2391-2394.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2391-2394
    • Rosenbaum, M.1    Murphy, E.M.2    Heymsfield, S.B.3    Matthews, D.E.4    Leibel, R.L.5
  • 56
    • 0013475483 scopus 로고    scopus 로고
    • Insulin modulates the activity of glucose responsive neurons in the ventromedial hypothalamic nucleus (VMN)
    • Routh VH, McArdle JJ, Spanswick DC, Levin BE & Ashford MLJ (1997). Insulin modulates the activity of glucose responsive neurons in the ventromedial hypothalamic nucleus (VMN). Abs Soc Neurosci 23, 577A.
    • (1997) Abs Soc Neurosci , vol.23
    • Routh, V.H.1    McArdle, J.J.2    Spanswick, D.C.3    Levin, B.E.4    Ashford, M.L.J.5
  • 57
    • 0029881125 scopus 로고    scopus 로고
    • Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
    • Schwartz MW, Peskind E, Raskind M, Boyko EJ, Porte J & D (1996). Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans. Nature Med 2, 589-593.
    • (1996) Nature Med , vol.2 , pp. 589-593
    • Schwartz, M.W.1    Peskind, E.2    Raskind, M.3    Boyko, E.J.4    Porte, J.D.5
  • 58
    • 12144275681 scopus 로고    scopus 로고
    • Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus
    • Song Z & Routh VH (2005). Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus. Diabetes 54, 15-22.
    • (2005) Diabetes , vol.54 , pp. 15-22
    • Song, Z.1    Routh, V.H.2
  • 61
    • 0034943548 scopus 로고    scopus 로고
    • Successful weight loss maintenance
    • Wing RR & Hill JO (2001). Successful weight loss maintenance. Ann Rev Nutr 21, 323-341.
    • (2001) Ann Rev Nutr , vol.21 , pp. 323-341
    • Wing, R.R.1    Hill, J.O.2
  • 62
    • 0036945699 scopus 로고    scopus 로고
    • Understanding the physiology of obesity: Review of recent developments in obesity research
    • Woods SC & Seeley RJ (2002). Understanding the physiology of obesity: Review of recent developments in obesity research. Int J Obes Relat Metab Disord 26 (Suppl. 4), S8-S10.
    • (2002) Int J Obes Relat Metab Disord , vol.26 , Issue.SUPPL. 4
    • Woods, S.C.1    Seeley, R.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.