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Volumn 55, Issue SUPPL. 2, 2006, Pages

Role of neuronal glucosensing in the regulation of energy homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOKINASE; INSULIN; LEPTIN;

EID: 33845534242     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-S016     Document Type: Review
Times cited : (45)

References (107)
  • 1
    • 84943984520 scopus 로고
    • The disabilities caused by hypophysectomy and their repair: The tuberal (hypothalamic) syndrome in the rat
    • Smith PE: The disabilities caused by hypophysectomy and their repair: the tuberal (hypothalamic) syndrome in the rat. JAMA 88:158-161, 1927
    • (1927) JAMA , vol.88 , pp. 158-161
    • Smith, P.E.1
  • 2
    • 0022538478 scopus 로고
    • Pancreatic adaptation in VMH obesity: In vivo compensatory response to altered neural input
    • Smith FJ, Campfield LA: Pancreatic adaptation in VMH obesity: in vivo compensatory response to altered neural input. Am J Physiol Regul Integr Comp Physiol 251:R70-R76, 1986
    • (1986) Am J Physiol Regul Integr Comp Physiol , vol.251
    • Smith, F.J.1    Campfield, L.A.2
  • 3
    • 0021276244 scopus 로고
    • Effects of hypothalamic lesion on pancreatic autonomic nerve activity in the rat
    • Yoshimatsu H, Niijima A, Oomura Y, Yamabe K, Katafuchi T: Effects of hypothalamic lesion on pancreatic autonomic nerve activity in the rat. Brain Res 303:147-152, 1984
    • (1984) Brain Res , vol.303 , pp. 147-152
    • Yoshimatsu, H.1    Niijima, A.2    Oomura, Y.3    Yamabe, K.4    Katafuchi, T.5
  • 4
    • 0022642366 scopus 로고
    • Plasma catecholamines associated with hypothalamically-elicited defense behavior
    • Stoddard-Apter SL, Bergdall VK, Townsend DW, Levin BE: Plasma catecholamines associated with hypothalamically-elicited defense behavior. Physiol Behav 36:867-873, 1986
    • (1986) Physiol Behav , vol.36 , pp. 867-873
    • Stoddard-Apter, S.L.1    Bergdall, V.K.2    Townsend, D.W.3    Levin, B.E.4
  • 5
    • 0023279899 scopus 로고
    • Ventromedial hypothalamic stimulation accelerates norepinephrine turnover in brown adipose tissue of rats
    • Saito M, Minokoshi Y, Shimazu T: Ventromedial hypothalamic stimulation accelerates norepinephrine turnover in brown adipose tissue of rats. Life Sci 41:193-197, 1987
    • (1987) Life Sci , vol.41 , pp. 193-197
    • Saito, M.1    Minokoshi, Y.2    Shimazu, T.3
  • 6
    • 0016423714 scopus 로고
    • Chronically reduced body weight in rats sustaining lesions of the lateral hypothalamus and maintained on palatable diets and drinking solutions
    • Boyle PC, Keesey RE: Chronically reduced body weight in rats sustaining lesions of the lateral hypothalamus and maintained on palatable diets and drinking solutions. J Comp Physiol Psychol 88:218-223, 1975
    • (1975) J Comp Physiol Psychol , vol.88 , pp. 218-223
    • Boyle, P.C.1    Keesey, R.E.2
  • 7
    • 0001643038 scopus 로고
    • Activity of single neurons in the hypothalamus feeding centers: Effect of glucose
    • Anand BK, Chhina GS, Sharma KN, Dua S, Singh B: Activity of single neurons in the hypothalamus feeding centers: effect of glucose. Am J Physiol 207:1146-1154, 1964
    • (1964) Am J Physiol , vol.207 , pp. 1146-1154
    • Anand, B.K.1    Chhina, G.S.2    Sharma, K.N.3    Dua, S.4    Singh, B.5
  • 8
    • 0000293983 scopus 로고
    • Reciprocal activities of the ventromedial and lateral hypothalamic area of cats
    • Oomura Y, Kimura K, Ooyama H, Maeo T, Iki M, Kuniyoshi N: Reciprocal activities of the ventromedial and lateral hypothalamic area of cats. Science 143:484-485, 1964
    • (1964) Science , vol.143 , pp. 484-485
    • Oomura, Y.1    Kimura, K.2    Ooyama, H.3    Maeo, T.4    Iki, M.5    Kuniyoshi, N.6
  • 9
    • 33646012618 scopus 로고    scopus 로고
    • The effects of oleic-acid (OA) on distinct populations of neurons in the hypothalamic arcuate nucleus (ARC) are dependent on extracellular glucose levels
    • Wang R, Cruciani-Guglielmacci C, Migrenne S, Magnan C, Cotero V, Routh VH: The effects of oleic-acid (OA) on distinct populations of neurons in the hypothalamic arcuate nucleus (ARC) are dependent on extracellular glucose levels. J Neurophysiol 95:1491-1498, 2006
    • (2006) J Neurophysiol , vol.95 , pp. 1491-1498
    • Wang, R.1    Cruciani-Guglielmacci, C.2    Migrenne, S.3    Magnan, C.4    Cotero, V.5    Routh, V.H.6
  • 10
    • 0021278836 scopus 로고
    • Glucose responding neurons in the nucleus tractus solitarius of the rat: In vitro study
    • Mizuno Y, Oomura Y: Glucose responding neurons in the nucleus tractus solitarius of the rat: in vitro study. Brain Res 307:109-116, 1984
    • (1984) Brain Res , vol.307 , pp. 109-116
    • Mizuno, Y.1    Oomura, Y.2
  • 11
    • 0016826446 scopus 로고
    • Excitatory and inhibitory effects of globus pallidus and substantia nigra on the lateral hypothalamic activity in the rat
    • Oomura Y, Nakamura T, Manchanda SK: Excitatory and inhibitory effects of globus pallidus and substantia nigra on the lateral hypothalamic activity in the rat. Pharm Biochem Behav 3:23-36, 1975
    • (1975) Pharm Biochem Behav , vol.3 , pp. 23-36
    • Oomura, Y.1    Nakamura, T.2    Manchanda, S.K.3
  • 12
    • 0031440266 scopus 로고    scopus 로고
    • Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels
    • Spanswick D, Smith MA, Groppi VE, Logan SD, Ashford ML: Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels. Nature 390:521-525, 1997
    • (1997) Nature , vol.390 , pp. 521-525
    • Spanswick, D.1    Smith, M.A.2    Groppi, V.E.3    Logan, S.D.4    Ashford, M.L.5
  • 13
    • 0033944152 scopus 로고    scopus 로고
    • Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats
    • Spanswick D, Smith MA, Mirshamsi S, Routh VH, Ashford ML: Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats. Nat Neurosci 3:757-758, 2000
    • (2000) Nat Neurosci , vol.3 , pp. 757-758
    • Spanswick, D.1    Smith, M.A.2    Mirshamsi, S.3    Routh, V.H.4    Ashford, M.L.5
  • 14
    • 3242765290 scopus 로고    scopus 로고
    • The regulation of glucose-excited (GE) neurons in the hypothalamic arcuate nucleus by glucose and feeding relevant peptides
    • Wang R, Liu X, Dunn-Meynell AA, Levin BE, Routh VH: The regulation of glucose-excited (GE) neurons in the hypothalamic arcuate nucleus by glucose and feeding relevant peptides. Diabetes 53:1959-1965, 2004
    • (2004) Diabetes , vol.53 , pp. 1959-1965
    • Wang, R.1    Liu, X.2    Dunn-Meynell, A.A.3    Levin, B.E.4    Routh, V.H.5
  • 15
    • 0030851022 scopus 로고    scopus 로고
    • Novel glucosensor for hypoglycemic detection localized to the portal vein
    • Hevener AL, Bergman RN, Donovan CM: Novel glucosensor for hypoglycemic detection localized to the portal vein. Diabetes 46:1521-1525, 1997
    • (1997) Diabetes , vol.46 , pp. 1521-1525
    • Hevener, A.L.1    Bergman, R.N.2    Donovan, C.M.3
  • 16
    • 0036178788 scopus 로고    scopus 로고
    • Low glucose-sensing cells in the carotid body
    • Pardal R, Lopez-Barneo J: Low glucose-sensing cells in the carotid body. Nat Neurosci 5:197-198, 2002
    • (2002) Nat Neurosci , vol.5 , pp. 197-198
    • Pardal, R.1    Lopez-Barneo, J.2
  • 17
    • 0033509334 scopus 로고    scopus 로고
    • Identification and characterization of glucoresponsive neurons in the enteric nervous system
    • Liu M, Seino S, Kirchgessner AL: Identification and characterization of glucoresponsive neurons in the enteric nervous system. J Neurosci 19:10305-10317, 1999
    • (1999) J Neurosci , vol.19 , pp. 10305-10317
    • Liu, M.1    Seino, S.2    Kirchgessner, A.L.3
  • 18
    • 0021367606 scopus 로고
    • Convergence of heptoportal glucose-sensitive afferent signals to glucose-sensitive units within the nucleus of the solitary tract
    • Adachi A, Shimizu N, Oomura Y, Kobashi M: Convergence of heptoportal glucose-sensitive afferent signals to glucose-sensitive units within the nucleus of the solitary tract. Neurosci Lett 46:215-218, 1984
    • (1984) Neurosci Lett , vol.46 , pp. 215-218
    • Adachi, A.1    Shimizu, N.2    Oomura, Y.3    Kobashi, M.4
  • 20
    • 0036627597 scopus 로고    scopus 로고
    • Multiple neural systems controlling food intake and body weight
    • Berthoud HR: Multiple neural systems controlling food intake and body weight. Neurosci Biobehav Rev 26:393-428, 2002
    • (2002) Neurosci Biobehav Rev , vol.26 , pp. 393-428
    • Berthoud, H.R.1
  • 21
    • 0033553449 scopus 로고    scopus 로고
    • Retrograde transynaptic pseudorabies virus infection of central autonomic circuits in neonatal rats
    • Rinaman L, Roesch MR, Card JP: Retrograde transynaptic pseudorabies virus infection of central autonomic circuits in neonatal rats. Brain Res Devel Brain Res 114:207-216, 1999
    • (1999) Brain Res Devel Brain Res , vol.114 , pp. 207-216
    • Rinaman, L.1    Roesch, M.R.2    Card, J.P.3
  • 22
    • 0024390058 scopus 로고
    • Serotonin and substance P colocalization in medullary projections to the nucleus tractus solitarius: Dual-colour immunohistochemistry combined with retrograde tracing
    • Thor KB, Helke CJ: Serotonin and substance P colocalization in medullary projections to the nucleus tractus solitarius: dual-colour immunohistochemistry combined with retrograde tracing. J Chem Neuroanat 2:139-148, 1989
    • (1989) J Chem Neuroanat , vol.2 , pp. 139-148
    • Thor, K.B.1    Helke, C.J.2
  • 25
    • 0031697756 scopus 로고    scopus 로고
    • Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus
    • Tritos NA, Vicent D, Gillette J, Ludwig DS, Flier ES, Maratos-Flier E: Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus. Diabetes 47:1687-1692, 1998
    • (1998) Diabetes , vol.47 , pp. 1687-1692
    • Tritos, N.A.1    Vicent, D.2    Gillette, J.3    Ludwig, D.S.4    Flier, E.S.5    Maratos-Flier, E.6
  • 26
    • 14644396121 scopus 로고    scopus 로고
    • Physiological changes in glucose differentially modulate the excitability of hypothalamic melanin-concentrating hormone and orexin neurons in situ
    • Burdakov D, Gerasimenko O, Verkhratsky A: Physiological changes in glucose differentially modulate the excitability of hypothalamic melanin-concentrating hormone and orexin neurons in situ. J Neurosci 25:2429-2433, 2005
    • (2005) J Neurosci , vol.25 , pp. 2429-2433
    • Burdakov, D.1    Gerasimenko, O.2    Verkhratsky, A.3
  • 29
    • 0029013644 scopus 로고
    • Metabolic inhibition and low internal ATP activate K-atp channels in rat dopaminergic substantia nigra neurones
    • Roper J, Ashcroft FM: Metabolic inhibition and low internal ATP activate K-atp channels in rat dopaminergic substantia nigra neurones. Pflugers Arch 430:44-54, 1995
    • (1995) Pflugers Arch , vol.430 , pp. 44-54
    • Roper, J.1    Ashcroft, F.M.2
  • 30
    • 0033976228 scopus 로고    scopus 로고
    • Localization of hindbrain glucoreceptive sites controlling food intake and blood glucose
    • Ritter S, Dinh TT, Zhang Y: Localization of hindbrain glucoreceptive sites controlling food intake and blood glucose. Brain Res 856:37-47, 2000
    • (2000) Brain Res , vol.856 , pp. 37-47
    • Ritter, S.1    Dinh, T.T.2    Zhang, Y.3
  • 31
    • 0141613642 scopus 로고    scopus 로고
    • Glucosensing neurons in the ventromedial hypothalamic nucleus (VMN) and hypoglycemia-associated autonomic failure (HAAF)
    • Routh VH: Glucosensing neurons in the ventromedial hypothalamic nucleus (VMN) and hypoglycemia-associated autonomic failure (HAAF). Diabetes Metab Res Rev 19:348-356, 2003
    • (2003) Diabetes Metab Res Rev , vol.19 , pp. 348-356
    • Routh, V.H.1
  • 32
    • 33645893473 scopus 로고    scopus 로고
    • Neuronal responses to transient hypoglycaemia in the dorsal vagal complex of the rat brainstem
    • Balfour RH, Hansen AMK, Trapp S: Neuronal responses to transient hypoglycaemia in the dorsal vagal complex of the rat brainstem. J Physiol (Lond) 570:469-484, 2006
    • (2006) J Physiol (Lond) , vol.570 , pp. 469-484
    • Balfour, R.H.1    Hansen, A.M.K.2    Trapp, S.3
  • 34
    • 0023759316 scopus 로고
    • Adenosine-5′-triphosphate-sensitive ion channels in neonatal rat cultured central neurones
    • Ashford MLJ, Sturgess NJ, Trout NJ, Gardner NJ, Hales CN: Adenosine-5′-triphosphate-sensitive ion channels in neonatal rat cultured central neurones. Pflugers Arch 412:297-304, 1988
    • (1988) Pflugers Arch , vol.412 , pp. 297-304
    • Ashford, M.L.J.1    Sturgess, N.J.2    Trout, N.J.3    Gardner, N.J.4    Hales, C.N.5
  • 35
    • 0035650534 scopus 로고    scopus 로고
    • Convergence of pre-and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus (VMN)
    • Song Z, Levin BE, McArdle JJ, Bakhos N, Routh VH: Convergence of pre-and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus (VMN). Diabetes 50:2673-2681, 2001
    • (2001) Diabetes , vol.50 , pp. 2673-2681
    • Song, Z.1    Levin, B.E.2    McArdle, J.J.3    Bakhos, N.4    Routh, V.H.5
  • 36
    • 0036303140 scopus 로고    scopus 로고
    • Glucokinase is the likely mediator of glucosensing in both glucose excited and glucose inhibited central neurons
    • Dunn-Meynell AA, Routh VH, Kang L, Gaspers L, Levin BE: Glucokinase is the likely mediator of glucosensing in both glucose excited and glucose inhibited central neurons. Diabetes 51:2056-2065, 2002
    • (2002) Diabetes , vol.51 , pp. 2056-2065
    • Dunn-Meynell, A.A.1    Routh, V.H.2    Kang, L.3    Gaspers, L.4    Levin, B.E.5
  • 37
    • 1442276966 scopus 로고    scopus 로고
    • Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons
    • Kang L, Routh VH, Kuzhikandathil EV, Gaspers L, Levin BE: Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons. Diabetes 53:549-559, 2004
    • (2004) Diabetes , vol.53 , pp. 549-559
    • Kang, L.1    Routh, V.H.2    Kuzhikandathil, E.V.3    Gaspers, L.4    Levin, B.E.5
  • 38
    • 0030067124 scopus 로고    scopus 로고
    • Banting Lecture 1995: A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm
    • Matschinsky FM: Banting Lecture 1995: A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. Diabetes 45:223-241, 1996
    • (1996) Diabetes , vol.45 , pp. 223-241
    • Matschinsky, F.M.1
  • 43
    • 0034090708 scopus 로고    scopus 로고
    • Functional glucokinase isoforms are expressed in rat brain
    • Roncero I, Alvarez E, Vazques P, Blazquez E: Functional glucokinase isoforms are expressed in rat brain. J Neurochem 74:1848-1857, 2000
    • (2000) J Neurochem , vol.74 , pp. 1848-1857
    • Roncero, I.1    Alvarez, E.2    Vazques, P.3    Blazquez, E.4
  • 45
    • 0029891192 scopus 로고    scopus 로고
    • The high-affinity sulphonylurea receptor regulates KATP channels in nerve terminals of the rat motor cortex
    • Lee K, Dixon AK, Rowe IC, Ashford ML, Richardson PJ: The high-affinity sulphonylurea receptor regulates KATP channels in nerve terminals of the rat motor cortex. J Neurochem 66:2562-2571, 1996
    • (1996) J Neurochem , vol.66 , pp. 2562-2571
    • Lee, K.1    Dixon, A.K.2    Rowe, I.C.3    Ashford, M.L.4    Richardson, P.J.5
  • 46
    • 0016191102 scopus 로고
    • Glucose inhibition of the glucose-sensitive neurone in the rat lateral hypothalamus
    • Oomura Y, Ooyama H, Sugimori M, Nakamura T, Yamada Y: Glucose inhibition of the glucose-sensitive neurone in the rat lateral hypothalamus. Nature 247:284-286, 1974
    • (1974) Nature , vol.247 , pp. 284-286
    • Oomura, Y.1    Ooyama, H.2    Sugimori, M.3    Nakamura, T.4    Yamada, Y.5
  • 47
    • 0029952838 scopus 로고    scopus 로고
    • Potassium channel dysfunction in hypothalamic glucose-receptive neurones of obese Zucker rats
    • Rowe IC, Boden PR, Ashford ML: Potassium channel dysfunction in hypothalamic glucose-receptive neurones of obese Zucker rats. J Physiol 497:365-377, 1996
    • (1996) J Physiol , vol.497 , pp. 365-377
    • Rowe, I.C.1    Boden, P.R.2    Ashford, M.L.3
  • 48
    • 0034721575 scopus 로고    scopus 로고
    • Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy
    • Pierre K, Pellerin L, Debernardi R, Riederer BM, Magistretti PJ: Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy. Neuroscience 100:617-627, 2000
    • (2000) Neuroscience , vol.100 , pp. 617-627
    • Pierre, K.1    Pellerin, L.2    Debernardi, R.3    Riederer, B.M.4    Magistretti, P.J.5
  • 49
    • 12144275681 scopus 로고    scopus 로고
    • Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus
    • Song Z, Routh VH: Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus. Diabetes 54:15-22, 2005
    • (2005) Diabetes , vol.54 , pp. 15-22
    • Song, Z.1    Routh, V.H.2
  • 50
    • 0016814940 scopus 로고
    • Effect of free fatty acid on the rat lateral hypothalamic neurons
    • Oomura Y, Nakamura T, Sugimori M, Yamada Y: Effect of free fatty acid on the rat lateral hypothalamic neurons. Physiol Behav 14:483-486, 1975
    • (1975) Physiol Behav , vol.14 , pp. 483-486
    • Oomura, Y.1    Nakamura, T.2    Sugimori, M.3    Yamada, Y.4
  • 51
    • 0025062565 scopus 로고
    • Hypothalamic neuronal activity responses to 3-hydroxybutyric acid, an endogenous organic acid
    • Minami T, Shimizu N, Duan S, Oomura Y: Hypothalamic neuronal activity responses to 3-hydroxybutyric acid, an endogenous organic acid. Brain Res 509:351-354, 1990
    • (1990) Brain Res , vol.509 , pp. 351-354
    • Minami, T.1    Shimizu, N.2    Duan, S.3    Oomura, Y.4
  • 52
    • 0023705985 scopus 로고
    • Effect of catecholamine-receptor antagonists on feeding-related neuronal activity in the central amygdaloid nucleus of the monkey: A microiontophoretic study
    • Jiang LH, Oomura Y: Effect of catecholamine-receptor antagonists on feeding-related neuronal activity in the central amygdaloid nucleus of the monkey: a microiontophoretic study. J Neurophysiol 60:536-548, 1988
    • (1988) J Neurophysiol , vol.60 , pp. 536-548
    • Jiang, L.H.1    Oomura, Y.2
  • 53
    • 0002712310 scopus 로고
    • Glucostatic mechanism of regulation of food intake
    • Mayer J: Glucostatic mechanism of regulation of food intake. N Engl J Med 249:13-16, 1953
    • (1953) N Engl J Med , vol.249 , pp. 13-16
    • Mayer, J.1
  • 54
    • 0014593248 scopus 로고
    • Increased feeding in response to decreased glucose utilization in the rat and monkey
    • Smith GP, Epstein AN: Increased feeding in response to decreased glucose utilization in the rat and monkey. Am J Physiol 217:1083-1087, 1969
    • (1969) Am J Physiol , vol.217 , pp. 1083-1087
    • Smith, G.P.1    Epstein, A.N.2
  • 55
    • 0026035949 scopus 로고
    • Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans
    • Heller SR, Cryer PE: Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans. Diabetes 40:223-226, 1991
    • (1991) Diabetes , vol.40 , pp. 223-226
    • Heller, S.R.1    Cryer, P.E.2
  • 56
    • 0018908713 scopus 로고
    • The effects of alimentary infusions of glucose, amino acids, or neutral fat on meal size in hungry pigs
    • Stephens DB: The effects of alimentary infusions of glucose, amino acids, or neutral fat on meal size in hungry pigs. J Physiol 299:453-463, 1980
    • (1980) J Physiol , vol.299 , pp. 453-463
    • Stephens, D.B.1
  • 57
    • 0021920704 scopus 로고
    • Influence of intraduodenal glucose on meal size and its modification by 2-deoxy-D-glucose or vagotomy in hungry pigs
    • Stephens DB: Influence of intraduodenal glucose on meal size and its modification by 2-deoxy-D-glucose or vagotomy in hungry pigs. Q J Exp Physiol 70:129-135, 1985
    • (1985) Q J Exp Physiol , vol.70 , pp. 129-135
    • Stephens, D.B.1
  • 58
    • 0024443938 scopus 로고
    • The effect of portal and jugular infused glucose, mannitol and saline on food intake in dogs
    • Bellinger LL, Williams FE: The effect of portal and jugular infused glucose, mannitol and saline on food intake in dogs. Physiol Behav 46:693-698, 1989
    • (1989) Physiol Behav , vol.46 , pp. 693-698
    • Bellinger, L.L.1    Williams, F.E.2
  • 60
    • 0022344825 scopus 로고
    • On-line continuous measurement of blood glucose and meal pattern in free-feeding rats: The role of glucose in meal initiation
    • Campfield LA, Brandon P, Smith FJ: On-line continuous measurement of blood glucose and meal pattern in free-feeding rats: the role of glucose in meal initiation. Brain Res Bull 14:605-616, 1985
    • (1985) Brain Res Bull , vol.14 , pp. 605-616
    • Campfield, L.A.1    Brandon, P.2    Smith, F.J.3
  • 61
  • 62
    • 0242268888 scopus 로고    scopus 로고
    • Extracellular glucose in rat ventromedial hypothalamus during acute and recurrent hypoglycemia
    • De Vries MG, Arseneau LM, Lawson ME, Beverly JL: Extracellular glucose in rat ventromedial hypothalamus during acute and recurrent hypoglycemia. Diabetes 52:2767-2773, 2003
    • (2003) Diabetes , vol.52 , pp. 2767-2773
    • De Vries, M.G.1    Arseneau, L.M.2    Lawson, M.E.3    Beverly, J.L.4
  • 63
    • 0028101988 scopus 로고
    • Extracellular glucose concentrations in mammalian brain: Continuous monitoring of changes during increased neuronal activity and upon limitation in oxygen supply in normo-, hypo-, and hyperglycemic animals
    • Silver IA, Erecinska M: Extracellular glucose concentrations in mammalian brain: continuous monitoring of changes during increased neuronal activity and upon limitation in oxygen supply in normo-, hypo-, and hyperglycemic animals. J Neurosci 14:5068-5076, 1994
    • (1994) J Neurosci , vol.14 , pp. 5068-5076
    • Silver, I.A.1    Erecinska, M.2
  • 64
    • 0027301239 scopus 로고
    • Influence of counterregulatory hormones, independently of hypoglycaemia, on cognitive function, warning symptoms and glucose kinetics
    • Kerr D, Diamond MP, Tamborlane WV, Kerr S, Sherwin RS: Influence of counterregulatory hormones, independently of hypoglycaemia, on cognitive function, warning symptoms and glucose kinetics. Clin Sci (Lond) 85:197-202, 1993
    • (1993) Clin Sci (Lond) , vol.85 , pp. 197-202
    • Kerr, D.1    Diamond, M.P.2    Tamborlane, W.V.3    Kerr, S.4    Sherwin, R.S.5
  • 66
    • 0015850411 scopus 로고
    • Infusion of 2-deoxy-D-glucose into the hepatic-portal system causes eating: Evidence for peripheral glucoreceptors
    • Novin D, VanderWeele DA, Rezek M: Infusion of 2-deoxy-D-glucose into the hepatic-portal system causes eating: evidence for peripheral glucoreceptors. Science 181:858-860, 1973
    • (1973) Science , vol.181 , pp. 858-860
    • Novin, D.1    Vanderweele, D.A.2    Rezek, M.3
  • 67
    • 0016587571 scopus 로고
    • Feeding induced by intracerebroventricular 2-deoxy-D-glucose in the rat
    • Miselis RR, Epstein AN: Feeding induced by intracerebroventricular 2-deoxy-D-glucose in the rat. Am J Physiol 229:1438-1447, 1975
    • (1975) Am J Physiol , vol.229 , pp. 1438-1447
    • Miselis, R.R.1    Epstein, A.N.2
  • 68
    • 0035795199 scopus 로고    scopus 로고
    • Immunotoxic destruction of distinct catecholamine subgroups produces selective impairment of glucoregulatory responses and neuronal activation
    • Ritter S, Bugarith K, Dinh TT: Immunotoxic destruction of distinct catecholamine subgroups produces selective impairment of glucoregulatory responses and neuronal activation. J Comp Neurol 432:197-216, 2001
    • (2001) J Comp Neurol , vol.432 , pp. 197-216
    • Ritter, S.1    Bugarith, K.2    Dinh, T.T.3
  • 69
    • 0034463846 scopus 로고    scopus 로고
    • Localization of glucokinase-like immunoreactivity in the rat lower brain stem: For possible location of brain glucose-sensing mechanisms
    • Maekawa F, Toyoda Y, Torii N, Miwa I, Thompson RC, Foster DL, Tsukahara S, Tsukamura H, Maeda K: Localization of glucokinase-like immunoreactivity in the rat lower brain stem: for possible location of brain glucose-sensing mechanisms. Endocrinology 141:375-384, 2000
    • (2000) Endocrinology , vol.141 , pp. 375-384
    • Maekawa, F.1    Toyoda, Y.2    Torii, N.3    Miwa, I.4    Thompson, R.C.5    Foster, D.L.6    Tsukahara, S.7    Tsukamura, H.8    Maeda, K.9
  • 70
    • 2342510308 scopus 로고    scopus 로고
    • Third ventricular alloxan reversibly impairs glucose counterregulatory responses
    • Sanders NM, Dunn-Meynell AA, Levin BE: Third ventricular alloxan reversibly impairs glucose counterregulatory responses. Diabetes 53:1230-1236, 2004
    • (2004) Diabetes , vol.53 , pp. 1230-1236
    • Sanders, N.M.1    Dunn-Meynell, A.A.2    Levin, B.E.3
  • 71
    • 0024805413 scopus 로고
    • Effect of hepatic portal glucose concentration on food intake and metabolism
    • Tordoff MG, Tluczek JP, Friedman MI: Effect of hepatic portal glucose concentration on food intake and metabolism Am J Physiol 257:R1474-R1480, 1989
    • (1989) Am J Physiol , vol.257
    • Tordoff, M.G.1    Tluczek, J.P.2    Friedman, M.I.3
  • 72
    • 0037312819 scopus 로고    scopus 로고
    • Leptin receptor-deficient obese Zucker rats reduce their food intake in response to a systemic supply of calories from glucose
    • Gilbert M, Magnan C, Turban S, Andre J, Guerre-Millo M: Leptin receptor-deficient obese Zucker rats reduce their food intake in response to a systemic supply of calories from glucose. Diabetes 52:277-282, 2003
    • (2003) Diabetes , vol.52 , pp. 277-282
    • Gilbert, M.1    Magnan, C.2    Turban, S.3    Andre, J.4    Guerre-Millo, M.5
  • 73
    • 0036065628 scopus 로고    scopus 로고
    • Central administration of oleic acid inhibits glucose production and food intake
    • Obici S, Feng Z, Morgan K, Stein D, Karkanias G, Rossetti L: Central administration of oleic acid inhibits glucose production and food intake. Diabetes 51:271-275, 2002
    • (2002) Diabetes , vol.51 , pp. 271-275
    • Obici, S.1    Feng, Z.2    Morgan, K.3    Stein, D.4    Karkanias, G.5    Rossetti, L.6
  • 74
    • 0023579692 scopus 로고
    • Glucose-induced norepinephrine levels and obesity resistance
    • Levin BE, Sullivan AC: Glucose-induced norepinephrine levels and obesity resistance. Am J Physiol 253:R475-R481, 1987
    • (1987) Am J Physiol , vol.253
    • Levin, B.E.1    Sullivan, A.C.2
  • 75
    • 0023198344 scopus 로고
    • Glucose, insulin and sympathoadrenal activation
    • Levin BE, Sullivan AC: Glucose, insulin and sympathoadrenal activation. J Auton Nerv Syst 20:233-242, 1987
    • (1987) J Auton Nerv Syst , vol.20 , pp. 233-242
    • Levin, B.E.1    Sullivan, A.C.2
  • 76
    • 0021739077 scopus 로고
    • Thermic effect of glucose in man: Obligatory and facultative thermogenesis
    • Acheson KJ, Ravussin E, Wahren J, Jequier E: Thermic effect of glucose in man: obligatory and facultative thermogenesis. J Clin Invest 74:1572-1580, 1984
    • (1984) J Clin Invest , vol.74 , pp. 1572-1580
    • Acheson, K.J.1    Ravussin, E.2    Wahren, J.3    Jequier, E.4
  • 77
    • 0024370868 scopus 로고
    • Glucose-induced sympathetic activation in obesity-prone and -resistant rats
    • Levin BE, Sullivan AC: Glucose-induced sympathetic activation in obesity-prone and -resistant rats. Int J Obes 13:235-246, 1989
    • (1989) Int J Obes , vol.13 , pp. 235-246
    • Levin, B.E.1    Sullivan, A.C.2
  • 78
    • 0026350902 scopus 로고
    • Glucose increases rat plasma norepinephrine levels by direct action on the brain
    • Levin BE: Glucose increases rat plasma norepinephrine levels by direct action on the brain. Am J Physiol Regul Integr Comp Physiol 261:R1351-R1357, 1991
    • (1991) Am J Physiol Regul Integr Comp Physiol , vol.261
    • Levin, B.E.1
  • 79
    • 0031049045 scopus 로고    scopus 로고
    • Intracarotid glucose infusions selectively increase Fos-like immunoreactivity in paraventricular, ventromedial and dorsomedial nuclei neurons
    • Dunn-Meynell AA, Govek E, Levin BE: Intracarotid glucose infusions selectively increase Fos-like immunoreactivity in paraventricular, ventromedial and dorsomedial nuclei neurons. Brain Res 748:100-106, 1997
    • (1997) Brain Res , vol.748 , pp. 100-106
    • Dunn-Meynell, A.A.1    Govek, E.2    Levin, B.E.3
  • 80
    • 0032547892 scopus 로고    scopus 로고
    • Reduced glucose-induced neuronal activation in the hypothalamus of diet-induced obese rats
    • Levin BE, Govek EK, Dunn-Meynell AA: Reduced glucose-induced neuronal activation in the hypothalamus of diet-induced obese rats. Brain Res 808:317-319, 1998
    • (1998) Brain Res , vol.808 , pp. 317-319
    • Levin, B.E.1    Govek, E.K.2    Dunn-Meynell, A.A.3
  • 81
    • 0002536285 scopus 로고
    • The effect of glucose on the activity of the adrenal nerve and pancreatic branch of the vagus nerve in the rabbit
    • Niijima A: The effect of glucose on the activity of the adrenal nerve and pancreatic branch of the vagus nerve in the rabbit. Neurosci Lett 1:159-162, 1975
    • (1975) Neurosci Lett , vol.1 , pp. 159-162
    • Niijima, A.1
  • 82
    • 0014483325 scopus 로고
    • Sympathetic regulation of insulin secretion: Its relation to diabetes mellitus
    • Porte D Jr: Sympathetic regulation of insulin secretion: its relation to diabetes mellitus. Arch Intern Med 123:252-260, 1969
    • (1969) Arch Intern Med , vol.123 , pp. 252-260
    • Porte Jr., D.1
  • 83
    • 0023213629 scopus 로고
    • The effect of intrahypothalamic injections of glucose on sympathetic efferent firing rate
    • Sakaguchi T, Bray GA: The effect of intrahypothalamic injections of glucose on sympathetic efferent firing rate. Brain Res Bull 18:591-595, 1987
    • (1987) Brain Res Bull , vol.18 , pp. 591-595
    • Sakaguchi, T.1    Bray, G.A.2
  • 84
    • 0024162399 scopus 로고
    • Sympathetic activity following PVN injections of glucose and insulin
    • Sakaguchi T, Bray GA: Sympathetic activity following PVN injections of glucose and insulin. Brain Res Bull 21:25-29, 1988
    • (1988) Brain Res Bull , vol.21 , pp. 25-29
    • Sakaguchi, T.1    Bray, G.A.2
  • 85
    • 0036913187 scopus 로고    scopus 로고
    • Hypothalamic insulin signaling is required for inhibition of glucose production
    • Obici S, Zhang BB, Karkanias G, Rossetti L: Hypothalamic insulin signaling is required for inhibition of glucose production. Nat Med 8:1376-1382, 2002
    • (2002) Nat Med , vol.8 , pp. 1376-1382
    • Obici, S.1    Zhang, B.B.2    Karkanias, G.3    Rossetti, L.4
  • 87
    • 0016704169 scopus 로고
    • Sympathetic control of hepatic glycogenolysis during glucopenia in man
    • Brodows RG, Pi S, Campbell RG: Sympathetic control of hepatic glycogenolysis during glucopenia in man. Metabolism 24:617-624, 1975
    • (1975) Metabolism , vol.24 , pp. 617-624
    • Brodows, R.G.1    Pi, S.2    Campbell, R.G.3
  • 89
    • 0028931891 scopus 로고
    • Local ventromedial hypothalamic glucopenia triggers counterregulatory hormone release
    • Borg WP, Sherwin RS, During MJ, Borg MA, Shulman GI: Local ventromedial hypothalamic glucopenia triggers counterregulatory hormone release. Diabetes 44:180-184, 1995
    • (1995) Diabetes , vol.44 , pp. 180-184
    • Borg, W.P.1    Sherwin, R.S.2    During, M.J.3    Borg, M.A.4    Shulman, G.I.5
  • 90
    • 0031038124 scopus 로고    scopus 로고
    • Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats
    • Borg MA, Sherwin RS, Borg WP, Tamborlane WV, Shulman GI: Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats. J Clin Invest 99:361-365, 1997
    • (1997) J Clin Invest , vol.99 , pp. 361-365
    • Borg, M.A.1    Sherwin, R.S.2    Borg, W.P.3    Tamborlane, W.V.4    Shulman, G.I.5
  • 91
    • 4644298411 scopus 로고    scopus 로고
    • Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses
    • Evans ML, McCrimmon RJ, Flanagan DE, Keshavarz T, Fan X, McNay EC, Jacob RJ, Sherwin RS: Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses. Diabetes 53:2542-2551, 2004
    • (2004) Diabetes , vol.53 , pp. 2542-2551
    • Evans, M.L.1    McCrimmon, R.J.2    Flanagan, D.E.3    Keshavarz, T.4    Fan, X.5    McNay, E.C.6    Jacob, R.J.7    Sherwin, R.S.8
  • 92
    • 33644696261 scopus 로고    scopus 로고
    • Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats
    • McCrimmon RJ, Evans ML, Fan X, McNay EC, Chan O, Ding Y, Zhu W, Gram DX, Sherwin RS: Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats. Diabetes 54:3169-3174, 2005
    • (2005) Diabetes , vol.54 , pp. 3169-3174
    • McCrimmon, R.J.1    Evans, M.L.2    Fan, X.3    McNay, E.C.4    Chan, O.5    Ding, Y.6    Zhu, W.7    Gram, D.X.8    Sherwin, R.S.9
  • 93
    • 0034115121 scopus 로고    scopus 로고
    • Presumed apoptosis and reduced arcuate nucleus neuropeptide Y and pro-opiomelanocortin mRNA in non-coma hypoglycemia
    • Tkacs NC, Dunn-Meynell AA, Levin BE: Presumed apoptosis and reduced arcuate nucleus neuropeptide Y and pro-opiomelanocortin mRNA in non-coma hypoglycemia. Diabetes 49:820-826, 2000
    • (2000) Diabetes , vol.49 , pp. 820-826
    • Tkacs, N.C.1    Dunn-Meynell, A.A.2    Levin, B.E.3
  • 94
    • 6344243041 scopus 로고    scopus 로고
    • Obesity-prone rats have pre-existing defects in their counterregulatory response to insulin-induced hypoglycemia
    • Tkacs NC, Levin BE: Obesity-prone rats have pre-existing defects in their counterregulatory response to insulin-induced hypoglycemia. Am J Physiol 287:R1110-R1115, 2004
    • (2004) Am J Physiol , vol.287
    • Tkacs, N.C.1    Levin, B.E.2
  • 95
    • 0021257444 scopus 로고
    • Reflex control of the autonomic nervous system activity from the glucose sensors in the liver in normal and midpontine-transected animals
    • Niijima A: Reflex control of the autonomic nervous system activity from the glucose sensors in the liver in normal and midpontine-transected animals. J Auton Nerv Sys 10:279-285, 1984
    • (1984) J Auton Nerv Sys , vol.10 , pp. 279-285
    • Niijima, A.1
  • 96
    • 0026027379 scopus 로고
    • Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia
    • Donovan CM, Halter JB, Bergman RN: Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia. Diabetes 40:155-158, 1991
    • (1991) Diabetes , vol.40 , pp. 155-158
    • Donovan, C.M.1    Halter, J.B.2    Bergman, R.N.3
  • 97
    • 33644668567 scopus 로고    scopus 로고
    • Celiac-superior mesenteric ganglionectomy, but not vagotomy, suppresses the sympathoadrenal response to insulin-induced hypoglycemia
    • Fujita S, Donovan CM: Celiac-superior mesenteric ganglionectomy, but not vagotomy, suppresses the sympathoadrenal response to insulin-induced hypoglycemia. Diabetes 54:3258-3264, 2005
    • (2005) Diabetes , vol.54 , pp. 3258-3264
    • Fujita, S.1    Donovan, C.M.2
  • 98
    • 0023937310 scopus 로고
    • Carotid sinus receptors participate in glucose homeostasis
    • Alvarez-Buylla R, de Alvarez-Buylla ER: Carotid sinus receptors participate in glucose homeostasis. Respir Physiol 72:347-360, 1988
    • (1988) Respir Physiol , vol.72 , pp. 347-360
    • Alvarez-Buylla, R.1    De Alvarez-Buylla, E.R.2
  • 101
    • 0026753163 scopus 로고
    • Intracarotid glucose-induced norepinephrine response and the development of diet-induced obesity
    • Levin BE: Intracarotid glucose-induced norepinephrine response and the development of diet-induced obesity. Int J Obes 16:451-457, 1992
    • (1992) Int J Obes , vol.16 , pp. 451-457
    • Levin, B.E.1
  • 102
    • 0031473060 scopus 로고    scopus 로고
    • 3H]glyburide binding to brain sulfonylurea receptors in obesity-prone and resistant rats by glucose
    • 3H]glyburide binding to brain sulfonylurea receptors in obesity-prone and resistant rats by glucose. Brain Res 776:146-153, 1997
    • (1997) Brain Res , vol.776 , pp. 146-153
    • Levin, B.E.1    Dunn-Meynell, A.A.2
  • 103
    • 0001181537 scopus 로고    scopus 로고
    • ATP) channel in ventromedial hypothalamic nucleus (VMN) of obesity-prone (DIO) rats
    • ATP) channel in ventromedial hypothalamic nucleus (VMN) of obesity-prone (DIO) rats. FASEB J 12:A864, 1998
    • (1998) FASEB J , vol.12
    • Routh, V.H.1    Levin, B.E.2    McArdle, J.J.3
  • 104
    • 0036786420 scopus 로고    scopus 로고
    • Reduced central leptin sensitivity in rats with diet-induced obesity
    • Levin BE, Dunn-Meynell AA: Reduced central leptin sensitivity in rats with diet-induced obesity. Am J Physiol 283:R941-R948, 2002
    • (2002) Am J Physiol , vol.283
    • Levin, B.E.1    Dunn-Meynell, A.A.2
  • 105
    • 0347988175 scopus 로고    scopus 로고
    • Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling prior to obesity onset
    • Levin BE, Dunn-Meynell AA, Banks WA: Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling prior to obesity onset. Am J Physiol 286:R143-R150, 2003
    • (2003) Am J Physiol , vol.286
    • Levin, B.E.1    Dunn-Meynell, A.A.2    Banks, W.A.3
  • 106
    • 15544374102 scopus 로고    scopus 로고
    • Reduced anorexic effects of insulin in obesity-prone rats and rats fed a moderate fat diet
    • Clegg DJ, Benoit SC, Reed JA, Woods SC, Levin BE: Reduced anorexic effects of insulin in obesity-prone rats and rats fed a moderate fat diet. Am J Physiol 288:R981-R986, 2005
    • (2005) Am J Physiol , vol.288
    • Clegg, D.J.1    Benoit, S.C.2    Reed, J.A.3    Woods, S.C.4    Levin, B.E.5
  • 107
    • 0142020848 scopus 로고    scopus 로고
    • Abnormalities of leptin and ghrelin regulation in obesity-prone juvenile rats
    • Levin BE, Dunn-Meynell AA, Ricci MR, Cummings DE: Abnormalities of leptin and ghrelin regulation in obesity-prone juvenile rats. Am J Physiol 285:E949-E957, 2003
    • (2003) Am J Physiol , vol.285
    • Levin, B.E.1    Dunn-Meynell, A.A.2    Ricci, M.R.3    Cummings, D.E.4


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