Novel role of phosphorylation in Fe-S cluster stability revealed by phosphomimetic mutations at Ser-138 of iron regulatory protein 1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 26, 1998, Pages 15235-15240

  Brown, Nina M ^a   Anderson, Sheila A ^b   Steffen, Daniel W ^b   Carpenter, Tami B ^b   Kennedy, M Claire ^c   Walden, William E ^a   Eisenstein, Richard S ^b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACONITATE HYDRATASE; ALANINE; ASPARTIC ACID; GLUTAMIC ACID; IRON REGULATORY FACTOR; IRON REGULATORY PROTEIN 1; IRON SULFUR PROTEIN; MESSENGER RNA; MUTANT PROTEIN; PROTEIN KINASE C; SERINE; UNCLASSIFIED DRUG;

ARTICLE; GENE EXPRESSION; IRON METABOLISM; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PHOSPHORYLATION; PROTEIN POLYMORPHISM; PROTEIN PROCESSING; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION REGULATION;

ACONITATE HYDRATASE; AEROBIOSIS; ALANINE; AMINO ACID SUBSTITUTION; ANAEROBIOSIS; ASPARTIC ACID; BINDING SITES; CYTOSOL; ESCHERICHIA COLI; GLUTAMIC ACID; IRON REGULATORY PROTEIN 1; IRON-REGULATORY PROTEINS; IRON-SULFUR PROTEINS; ISOENZYMES; KINETICS; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; RNA-BINDING PROTEINS; SERINE;

EID: 0032417611     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.26.15235     Document Type: Article

References (57)

1. Crichton, R. R. (1991) Inorganic Biochemistry of Iron Metabolism (Ellis Horwood, New York).
2. Halliwell, B. & Gutteridge, J. M. C. (1986) Arch. Biochem. Biophys. 246, 501-514.
3. Williams, R. J. P. (1990) in Iron Transport and Storage, eds. Ponka, P., Schulman, H. M. & Woodworth, R. C. (CRC, Boca Raton, FL), pp. 1-16.
4. Eisenstein, R. S., Kennedy, M. C. & Beinert, H. (1997) in Metal Ions in Gene Regulation, eds. Silver, S. & Walden, W. (International Thomson, New York), pp. 157-216.
5. Hentze, M. W., Caughman, S. W., Rouault, T. A., Barriocanal, J. G., Dancis, A., Harford, J. B. & Klausner, R. D. (1987) Science 238, 1570-1573.
6. Cox, T. C., Bawden, M. J., Martin, A. & May, B. K. (1991) EMBO J. 10, 1891-1902.
7. Dandekar, T., Stripecke, R., Gray, N. K., Goossen, B., Constable, A., Johansson, H. E. & Hentze, M. W. (1991) EMBO J. 10, 1903-1909.
8. Kohler, S. A., Henderson, B. R. & Kühn, L. C. (1995) J. Biol. Chem. 270, 30781-30786.
9. Gunshin, H., Mackenzie, B., Berger, U., Gunshin, Y., Romero, M., Boron, W., Nussberger, S., Gollan, J. & Hediger, M. (1997) Nature (London) 388, 482-488.
10. Kennedy, M. C., Mende-Mueller, L., Blondin, G. A. & Beinert, H. (1992) Proc. Natl. Acad. Sci. USA 89, 11730-11734.
11. Haile, D. J., Rouault, T. A., Harford, J. B., Kennedy, M. C., Blondin, G. A., Beinert, H. & Klausner, R. D. (1992) Proc. Natl. Acad. Sci. USA 89, 11735-11739.
12. Kaptain, S., Downey, W. E., Tang, C., Philpott, C., Haile, D., Orloff, D. G., Harford, J. B., Rouault, T. A. & Klausner, R. D. (1991) Proc. Natl. Acad. Sci. USA 88, 10109-10113.
13. Guo, B., Phillips, J. D., Yu, Y. & Leibold, E. A. (1995) J. Biol. Chem. 270, 21645-21651.
14. Samaniego, F., Chin, J., Iwai, K., Rouault, T. A. & Klausner, R. D. (1994) J. Biol. Chem. 269, 30904-30910.
15. Hentze, M. W. & Kühn, L. C. (1996) Proc. Natl. Acad. Sci. USA 93, 8175-8182.
16. Kennedy, M. C., Antholine, W. E. & Beinert, H. (1997) J. Biol. Chem. 272, 20340-20347.
17. Cairo, G. & Pietrangelo, A. (1995) Eur. J. Biochem. 232, 358-363.
18. Hanson, E. & Leibold, E. A. (1998) J. Biol. Chem. 273, 7588-7593.
19. Eisenstein, R. S., Tuazon, P. T., Schalinske, K. L., Anderson, S. A. & Traugh, J. A. (1993) J. Biol. Chem. 268, 27363-27370.
20. Schalinske, K. L. & Eisenstein, R. S. (1996) J. Biol. Chem. 271, 7168-7176.
21. Schalinske, K. L., Anderson, S. A., Tuazon, P. T., Chen, O. S., Kennedy, M. C. & Eisenstein, R. S. (1997) Biochemistry 36, 3950-3958.
22. Basilion, J. P., Rouault, T. A., Massinople, C. M., Klausner, R. D. & Burgess, W. H. (1994) Proc. Natl. Acad. Sci. USA 91, 574-578.
23. Neupert, B., Menotti, E. & Kühn, L. C. (1995) Nucleic Acids Res. 23, 2579-2583.
24. Sherman, F. (1991) Methods Enzymol. 194, 3-21.
25. Hassett, R. F., Romeo, A. M. & Kosman, D. J. (1998) J. Biol. Chem. 273, 7628-7636.
26. Marini, F., Naeem, A. & Lapeyre, J. N. (1993) Nucleic Acids Res 21, 2277-2278.
27. Patiño, M. M. & Walden, W. E. (1992) J. Biol. Chem. 267, 19011-19016.
28. Kennedy, M. C., Emptage, M. H., Dreyer, J. L. & Beinert, H. (1983) J. Biol. Chem. 258, 11098-11105.
29. Groves, W. E., Davis, F. C. & Sells, B. H. (1968) Anal. Biochem. 22, 195-210.
30. Ke, Y., Wu, J., Leibold, E. A., Walden, W. E. & Theil, E. C. (1998) J. Biol. Chem. 273, 23637-23640.
31. Basilion, J. P., Kennedy, M. C., Beinert, H., Massinople, C. M., Klausner, R. D. & Rouault, T. A. (1994) Arch. Biochem. Biophys. 311, 517-522.
32. Ogur, M., Coker, L. & Ogur, S. (1964) Biochem. Biophys. Res. Commun. 14, 193-197.
33. Gardner, P. R. & Fridovich, I. (1991) J. Biol. Chem. 266, 19328-19333.
34. Gardner, P. R., Raineri, I., Epstein, L. B. & White, C. W. (1995) J. Biol. Chem. 270, 13399-13405.
35. Kent, T. A., Dreyer, J. L., Kennedy, M. C., Huynh, B. H., Emptage, M. H., Beinert, H. & Münck, E. (1982) Proc. Natl. Acad. Sci. USA 79, 1096-1100.
36. Barton, H. A., Eisenstein, R. S., Bomford, A. & Munro, H. N. (1990) J. Biol. Chem. 265, 7000-7008.
37. Haile, D. J., Hentze, M. W., Rouault, T. A., Harford, J. B. & Klausner, R. D. (1989) Mol. Cell. Biol. 9, 5055-5061.
38. Swenson, G. R., Patiño, M. M., Beck, M. M., Gaffield, L. & Walden, W. E. (1991) Biol. Met. 4, 48-55.
39. Testa, U., Petrini, M., Quaranta, M. T., Pelosi-Testa, E., Mastroberardino, G., Camagna, A., Boccoli, G., Sargiacomo, M., Isacchi, G., Cozzi, A., et al. (1989) J. Biol. Chem. 264, 13181-13197.
40. Testa, U., Kühn, L., Petrini, M., Quaranta, M. T., Pelosi, E. & Peschle, C. (1991) J. Biol. Chem. 266, 13925-13930.
41. Andreesen, R., Osterholz, J., Bodemann, H., Bross, K. J., Costabel, U. & Lohr, G. W. (1984) Blut 49, 195-202.
42. Seiser, C., Teixeira, S. & Kühn, L. C. (1993) J. Biol. Chem. 268, 13074-13080.
43. Teixeira, S. & Kühn, L. C. (1991) Eur. J. Biochem. 202, 819-826.
44. Demple, B. (1996) Gene 179, 53-57.
45. Unden, G. & Schirawski, J. (1997) Mol. Microbiol. 25, 205-210.
46. Khoroshilova, N., Popescu, C., Münck, E., Beinert, H. & Kiley, P. (1997) Proc. Natl. Acad. Sci. USA 94, 6087-6092.
47. Hidalgo, E., Ding, H. & Demple, B. (1997) Cell 88, 121-129.
48. Recalcati, S., Taramelli, D., Conte, D. & Cairo, G. (1998) Blood 91, 1059-1066.
49. Fridovich, I. (1997) J. Biol. Chem. 272, 18515-18517.
50. Moradas-Ferreira, P., Costa, V., Piper, P. & Mager, W. (1996) Mol. Microbiol. 19, 651-658.
51. Bilinski, T., Krawiec, Z., Liczmanski, A. & Litwinska, J. (1985) Biochem. Biophys. Res. Commun. 130, 533-539.
52. Flint, D. H., Tuminello, J. F. & Emptage, M. H. (1993) J. Biol. Chem. 268, 22369-22376.
53. Flint, D. H., Smyk-Randall, E., Tuminello, J. F., Draczynska-Lusiak, B. & Brown, O. R. (1993) J. Biol. Chem. 268, 25547-25552.
54. Brown, R. H., Jr. (1997) Arch. Neurol. 54, 1246-1250.
55. Lauble, H., Kennedy, M. C., Beinert, H. & Stout, C. D. (1992) Biochemistry 31, 2735-2748.
56. Klausner, R. D., Stout, C. D. & Rouault, T. A. (1994) Chem. Biol. 1, viv-xv.
57. Pantopoulos, K. & Hentze, M. W. (1995) EMBO J. 14, 2917-2924.