Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe-S cluster

EMBO Journal

Volumn 25, Issue 3, 2006, Pages 544-553

  Clarke, Stephen L ^a,d   Vasanthakumar, Aparna ^a   Anderson, Sheila A ^a   Pondarré, Corinne ^b   Koh, Cheryl M ^a   Deck, Kathryn M ^a   Pitula, Joseph S ^a   Epstein, Charles J ^c   Fleming, Mark D ^b   Eisenstein, Richard S ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Fe S protein; Iron homeostasis; Iron regulatory protein 1; Phosphorylation; Protein degradation

Indexed keywords

CYSTEINE; FERROUS SULFIDE; IRON REGULATORY PROTEIN 1; MUTANT PROTEIN; RNA BINDING PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING KINETICS; CONTROLLED STUDY; DEGRADATION KINETICS; GENETIC DISORDER; GENETIC MODEL; HUMAN; IRON RESPONSIVE ELEMENT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN RNA BINDING; REGULATORY MECHANISM;

ANIMALS; CELL LINE; HEMIN; HUMANS; IRON; IRON REGULATORY PROTEIN 1; MICE; MICE, KNOCKOUT; MUTATION; PHOSPHORYLATION; RNA, MESSENGER; RNA-BINDING PROTEINS; SERINE;

ANIMALIA;

EID: 32544435147     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600954     Document Type: Article

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