A conserved tyrosine in the β2 subunit M4 segment is a determinant of γ-aminobutyric acid type A receptor sensitivity to propofol

Anesthesiology

Volumn 107, Issue 3, 2007, Pages 412-418

  Richardson, James E ^a   Garcia, Paul S ^a   O'Toole, Kate K ^b   Derry, Jason M C ^c   Bell, Shannon V ^a   Jenkins, Andrew ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ETOMIDATE; PREGNENOLONE; PROPOFOL; TRYPTOPHAN; TYROSINE; ANESTHETIC AGENT; INTRAVENOUS ANESTHETIC AGENT;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG MECHANISM; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; AMINO ACID SEQUENCE; CELL CULTURE; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; INFUSION PUMP; METHODOLOGY; MOLECULAR GENETICS; MUTATION; PATCH CLAMP; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANESTHETICS, GENERAL; ANESTHETICS, INTRAVENOUS; CELLS, CULTURED; ETOMIDATE; HUMANS; INFUSION PUMPS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PATCH-CLAMP TECHNIQUES; PREGNENOLONE; PROPOFOL; RECEPTORS, GABA-A; TRANSFECTION; TRYPTOPHAN; TYROSINE;

EID: 34548261407     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/01.anes.0000278875.36639.2c     Document Type: Article

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