Differential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs

Biochemical Journal

Volumn 406, Issue 2, 2007, Pages 223-236

  Johnson, Joanne E ^a   Goulding, Rebecca E ^b   Ding, Ziwei ^a   Partovi, Amir ^a   Anthony, Kira V ^b   Beaulieu, Nadine ^b   Tazmini, Ghazaleh ^b   Cornell, Rosemary B ^a   Kay, Robert J ^b  

^a SIMON FRASER UNIVERSITY   (Canada)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

C1 domain; Diacylglycerol (DAG); Guanine nucleotide exchange factor (GEF); Membrane binding; Phorbol ester

Indexed keywords

C1 DOMAIN; DIACYLGLYCEROL (DAG); GUANINE-NUCLEOTIDE-EXCHANGE FACTOR (GEF); MEMBRANE BINDING; PHORBOL ESTERS;

ENZYMES; ESTERS; GLYCEROL; LIGANDS; NUCLEOTIDES; PHOSPHOLIPIDS;

CELL MEMBRANES;

BINDING PROTEIN; DIACYLGLYCEROL; GLUTATHIONE TRANSFERASE; GUANINE NUCLEOTIDE RELEASING PROTEIN; GUANINE NUCLEOTIDE RELEASING PROTEIN 1; GUANINE NUCLEOTIDE RELEASING PROTEIN 2; GUANINE NUCLEOTIDE RELEASING PROTEIN 3; GUANINE NUCLEOTIDE RELEASING PROTEIN 4 ALPHA; GUANINE NUCLEOTIDE RELEASING PROTEIN 4 BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MEMBRANE BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANIONS; CELL LINE; CELL MEMBRANE; DIGLYCERIDES; DNA-BINDING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHORBOL ESTERS; PHOSPHOLIPIDS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RAS PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

EID: 34548167778     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20070294     Document Type: Article

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