-
1
-
-
0029955128
-
Control of ras activation
-
Downward J. Control of ras activation. Cancer Surv. 1996;27:87-100.
-
(1996)
Cancer Surv
, vol.27
, pp. 87-100
-
-
Downward, J.1
-
2
-
-
0037306522
-
The Ras/MAPK cascade and the control of positive selection
-
Alberola-Ila J, Hernandez-Hoyos G, The Ras/MAPK cascade and the control of positive selection. Immunol Rev. 2003;191:79-96.
-
(2003)
Immunol Rev
, vol.191
, pp. 79-96
-
-
Alberola-Ila, J.1
Hernandez-Hoyos, G.2
-
3
-
-
0038578688
-
GTPases and T cell activation
-
Cantrell DA. GTPases and T cell activation. Immunol Rev. 2003;192:122-130.
-
(2003)
Immunol Rev
, vol.192
, pp. 122-130
-
-
Cantrell, D.A.1
-
4
-
-
0032010114
-
Molecular dissection of B cell antigen receptor signaling
-
Kurosaki T. Molecular dissection of B cell antigen receptor signaling (review). Int J Mol Mod. 1998;1:515-527.
-
(1998)
Int J Mol Mod
, vol.1
, pp. 515-527
-
-
Kurosaki, T.1
-
5
-
-
3042522852
-
B cell antigen receptor signaling 101
-
Dal Porto JM, Gauld SB, Merrell KT, Mills D, Pugh-Bernard AE, Cambier J. B cell antigen receptor signaling 101. Mol Immunol. 2004;41:599-613.
-
(2004)
Mol Immunol
, vol.41
, pp. 599-613
-
-
Dal Porto, J.M.1
Gauld, S.B.2
Merrell, K.T.3
Mills, D.4
Pugh-Bernard, A.E.5
Cambier, J.6
-
6
-
-
0025193117
-
Stimulation of p21 ras upon T-cell activation
-
Downward J, Graves JD, Warne PH, Rayter S, Cantrell DA. Stimulation of p21 ras upon T-cell activation. Nature. 1990;346:719-723.
-
(1990)
Nature
, vol.346
, pp. 719-723
-
-
Downward, J.1
Graves, J.D.2
Warne, P.H.3
Rayter, S.4
Cantrell, D.A.5
-
7
-
-
0026708592
-
Role of protein kinase C in T-cell antigen receptor regulation of p21ras: Evidence that two p21ras regulatory pathways coexist in T cells
-
Izquierdo M, Downward J, Graves JD, Cantrell DA. Role of protein kinase C in T-cell antigen receptor regulation of p21ras: evidence that two p21ras regulatory pathways coexist in T cells. Mol Cell Biol. 1992;12:3305-3312.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 3305-3312
-
-
Izquierdo, M.1
Downward, J.2
Graves, J.D.3
Cantrell, D.A.4
-
8
-
-
0032524389
-
RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs
-
Ebinu JO, Bottorff DA, Chan EY, Stang SL, Dunn RJ, Stone JC. RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Science. 1998;280:1082-1086.
-
(1998)
Science
, vol.280
, pp. 1082-1086
-
-
Ebinu, J.O.1
Bottorff, D.A.2
Chan, E.Y.3
Stang, S.L.4
Dunn, R.J.5
Stone, J.C.6
-
9
-
-
0034658333
-
RasGRP links T-cell receptor signaling to Ras
-
Ebinu JO, Stang SL, Teixeira C, et al. RasGRP links T-cell receptor signaling to Ras. Blood. 2000;95:3199-3203.
-
(2000)
Blood
, vol.95
, pp. 3199-3203
-
-
Ebinu, J.O.1
Stang, S.L.2
Teixeira, C.3
-
10
-
-
0031784267
-
Regulation of RasGRP via a phorbol ester-responsive C1 domain
-
Tognon CE, Kirk HE, Passmore LA, Whitehead IP, Der CJ, Kay RJ. Regulation of RasGRP via a phorbol ester-responsive C1 domain. Mol Cell Biol. 1998;18:6995-7008.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6995-7008
-
-
Tognon, C.E.1
Kirk, H.E.2
Passmore, L.A.3
Whitehead, I.P.4
Der, C.J.5
Kay, R.J.6
-
11
-
-
0034061660
-
The guanine nucleotide exchange factor RasGRP is a high-affinity target for diacylglycerol and phorbol esters
-
Lorenzo PS, Beheshti M, Pettit GR, Stone JC, Blumberg PM. The guanine nucleotide exchange factor RasGRP is a high-affinity target for diacylglycerol and phorbol esters. Mol Pharmacol. 2000;57:840-846.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 840-846
-
-
Lorenzo, P.S.1
Beheshti, M.2
Pettit, G.R.3
Stone, J.C.4
Blumberg, P.M.5
-
12
-
-
0034303371
-
RasGRP is essential for mouse thymocyte differentiation and TCR signaling
-
Dower NA, Stang SL, Bottorff DA, et al. RasGRP is essential for mouse thymocyte differentiation and TCR signaling. Nat Immunol. 2000;1:317-321.
-
(2000)
Nat Immunol
, vol.1
, pp. 317-321
-
-
Dower, N.A.1
Stang, S.L.2
Bottorff, D.A.3
-
13
-
-
0036848708
-
RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation
-
Priatel JJ, Teh SJ, Dower NA, Stone JC, Teh HS. RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation. Immunity. 2002;17:617-627.
-
(2002)
Immunity
, vol.17
, pp. 617-627
-
-
Priatel, J.J.1
Teh, S.J.2
Dower, N.A.3
Stone, J.C.4
Teh, H.S.5
-
14
-
-
0042237772
-
Integration of DAG signaling systems mediated by PKC-dependent phosphorylation of RasGRP3
-
Teixeira C, Stang SL, Zheng Y, Beswick NS, Stone JC. Integration of DAG signaling systems mediated by PKC-dependent phosphorylation of RasGRP3. Blood. 2003;102:1414-1420.
-
(2003)
Blood
, vol.102
, pp. 1414-1420
-
-
Teixeira, C.1
Stang, S.L.2
Zheng, Y.3
Beswick, N.S.4
Stone, J.C.5
-
15
-
-
0034671815
-
Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: Potential role of additional diacylglycerol binding proteins
-
Puente LG, Stone JC, Ostergaard HL. Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins. J Immunol. 2000;165:6865-6871.
-
(2000)
J Immunol
, vol.165
, pp. 6865-6871
-
-
Puente, L.G.1
Stone, J.C.2
Ostergaard, H.L.3
-
16
-
-
0035117119
-
Phorbol esters modulate the Ras exchange factor RasGRP3
-
Lorenzo PS, Kung JW, Bottortf DA, Garfield SH, Stone JC, Blumberg PM. Phorbol esters modulate the Ras exchange factor RasGRP3. Cancer Res. 2001;61:943-949.
-
(2001)
Cancer Res
, vol.61
, pp. 943-949
-
-
Lorenzo, P.S.1
Kung, J.W.2
Bottortf, D.A.3
Garfield, S.H.4
Stone, J.C.5
Blumberg, P.M.6
-
17
-
-
0025352187
-
Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
-
Morgenstern JP, Land H. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 1990;18:3587-3596.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 3587-3596
-
-
Morgenstern, J.P.1
Land, H.2
-
18
-
-
3242698721
-
Open tubular immobilized metal ion affinity chromatography combined with MALD1 MS and MS/MS for identification of protein phosphorylation sites
-
Liu H, Stupak J, Zheng J, et al. Open tubular immobilized metal ion affinity chromatography combined with MALD1 MS and MS/MS for identification of protein phosphorylation sites. Anal Chem. 2004;76:4223-4232.
-
(2004)
Anal Chem
, vol.76
, pp. 4223-4232
-
-
Liu, H.1
Stupak, J.2
Zheng, J.3
-
19
-
-
0031014969
-
Rapid Ca2+-mediated activation of Rap1 in human platelets
-
Franke B, Akkerman JW, Bos JL. Rapid Ca2+-mediated activation of Rap1 in human platelets. EMBO J. 1997;16:252-259.
-
(1997)
EMBO J
, vol.16
, pp. 252-259
-
-
Franke, B.1
Akkerman, J.W.2
Bos, J.L.3
-
20
-
-
3042630992
-
PKC-delta associates with and is involved in the phosphorylation of RasGRPS in response to phorbol esters
-
Brodie C, Steinhart R, Kazimirsky G, et al. PKC-delta associates with and is involved in the phosphorylation of RasGRPS in response to phorbol esters. Mol Pharmacol. 2004;66:76-84.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 76-84
-
-
Brodie, C.1
Steinhart, R.2
Kazimirsky, G.3
-
21
-
-
0037067713
-
RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs: Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function
-
Yang Y, Li L, Wong GW, et al. RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs: identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function. J Biol Chem. 2002;277:25756-25774.
-
(2002)
J Biol Chem
, vol.277
, pp. 25756-25774
-
-
Yang, Y.1
Li, L.2
Wong, G.W.3
-
22
-
-
0037163027
-
RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia
-
Reuther GW, Lambert QT, Rebhun JF, Caligiuri MA, Quilliam LA, Der CJ. RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia. J Biol Chem. 2002;277:30508-30514.
-
(2002)
J Biol Chem
, vol.277
, pp. 30508-30514
-
-
Reuther, G.W.1
Lambert, Q.T.2
Rebhun, J.F.3
Caligiuri, M.A.4
Quilliam, L.A.5
Der, C.J.6
-
23
-
-
0034682779
-
CaIDAG-GEFIII activation of Ras, R-Ras, and Rap1
-
Yamashita S, Mochizuki N, Ohba Y, et al. CaIDAG-GEFIII activation of Ras, R-Ras, and Rap1. J Biol Chem. 2000;275:25488-25493.
-
(2000)
J Biol Chem
, vol.275
, pp. 25488-25493
-
-
Yamashita, S.1
Mochizuki, N.2
Ohba, Y.3
-
24
-
-
0032478610
-
Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein Kinase C
-
Marais R, Light Y, Mason C, Paterson H, Olson MF, Marshall CJ. Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein Kinase C. Science. 1998;280:109-112.
-
(1998)
Science
, vol.280
, pp. 109-112
-
-
Marais, R.1
Light, Y.2
Mason, C.3
Paterson, H.4
Olson, M.F.5
Marshall, C.J.6
-
25
-
-
0036209077
-
Novel "nonkinase" phorbol ester receptors: The C1 domain connection
-
Kazanletz MG. Novel "nonkinase" phorbol ester receptors: the C1 domain connection. Mol Pharmacol. 2002;61:759-767.
-
(2002)
Mol Pharmacol
, vol.61
, pp. 759-767
-
-
Kazanletz, M.G.1
-
26
-
-
0347593996
-
Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling
-
Oh-hora M, Johmura S, Hashimoto A, Hikida M, Kurosaki T. Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling. J Exp Med. 2003;198:1841-1851.
-
(2003)
J Exp Med
, vol.198
, pp. 1841-1851
-
-
Oh-Hora, M.1
Johmura, S.2
Hashimoto, A.3
Hikida, M.4
Kurosaki, T.5
-
27
-
-
0029739626
-
Immunodeficiency in protein kinase cbeta-deficient mice
-
Leitges M, Schmedt C, Guinamard R, et al. Immunodeficiency in protein kinase cbeta-deficient mice. Science. 1993;273:788-791.
-
(1993)
Science
, vol.273
, pp. 788-791
-
-
Leitges, M.1
Schmedt, C.2
Guinamard, R.3
-
28
-
-
0037171439
-
Protein kinase Cdelta controls self-antigen-induced B-cell tolerance
-
Mecklenbrauker I, Saijo K, Zheng NY, Leitges M, Tarakhovsky A. Protein kinase Cdelta controls self-antigen-induced B-cell tolerance. Nature. 2002;416:860-865.
-
(2002)
Nature
, vol.416
, pp. 860-865
-
-
Mecklenbrauker, I.1
Saijo, K.2
Zheng, N.Y.3
Leitges, M.4
Tarakhovsky, A.5
-
29
-
-
0037171731
-
Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta
-
Miyamoto A, Nakayama K, Imaki H, et al. Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta. Nature. 2002;416:865-869.
-
(2002)
Nature
, vol.416
, pp. 865-869
-
-
Miyamoto, A.1
Nakayama, K.2
Imaki, H.3
-
30
-
-
0037143671
-
B-cell signaling: Protein kinase Cdelta puts the brakes on
-
Mathis D, King GL. B-cell signaling: protein kinase Cdelta puts the brakes on. Curr Biol. 2002;12:R554-R556.
-
(2002)
Curr Biol
, vol.12
-
-
Mathis, D.1
King, G.L.2
-
31
-
-
3142737230
-
B cell receptor-induced cAMP-response element-binding protein activation in B lymphocytes requires novel protein kinase Cdelta
-
Blois JT, Mataraza JM, Mecklenbrauker I, Tarakhovsky A, Chiles TC. B cell receptor-induced cAMP-response element-binding protein activation in B lymphocytes requires novel protein kinase Cdelta. J Biol Chem. 2004;279:30123-30132.
-
(2004)
J Biol Chem
, vol.279
, pp. 30123-30132
-
-
Blois, J.T.1
Mataraza, J.M.2
Mecklenbrauker, I.3
Tarakhovsky, A.4
Chiles, T.C.5
-
32
-
-
9344264018
-
Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation
-
Aiba Y, Oh-hora M, Kiyonaka S, et al. Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation. Proc Natl Acad Sci U SA. 2004;101:16612-16617.
-
(2004)
Proc Natl Acad Sci U SA
, vol.101
, pp. 16612-16617
-
-
Aiba, Y.1
Oh-Hora, M.2
Kiyonaka, S.3
-
33
-
-
0029935183
-
Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1
-
Porfiri E, McCormick F. Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1. J Biol Chem. 1996;271:5871-5877.
-
(1996)
J Biol Chem
, vol.271
, pp. 5871-5877
-
-
Porfiri, E.1
McCormick, F.2
-
34
-
-
0037631371
-
Phosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortex
-
Yang H, Cooley D, Legakis JE, Ge Q, Andrade R, Mattingly RR. Phosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortex. J Biol Chem. 2003;278:13278-13285.
-
(2003)
J Biol Chem
, vol.278
, pp. 13278-13285
-
-
Yang, H.1
Cooley, D.2
Legakis, J.E.3
Ge, Q.4
Andrade, R.5
Mattingly, R.R.6
-
35
-
-
2442683012
-
Rap2B-dependent stimulation of phospholipase C-epsilon by epidermal growth factor receptor mediated by c-Src phosphorylation of RasGRP3
-
Slope MB, Vom Dorp F, Szatkowski D, et al. Rap2B-dependent stimulation of phospholipase C-epsilon by epidermal growth factor receptor mediated by c-Src phosphorylation of RasGRP3. Mol Cell Biol. 2004;24:4664-4676.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4664-4676
-
-
Slope, M.B.1
Vom Dorp, F.2
Szatkowski, D.3
|