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Volumn 105, Issue 9, 2005, Pages 3648-3654

Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; DIACYLGLYCEROL; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C GAMMA2; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RAS PROTEIN; T LYMPHOCYTE RECEPTOR; THREONINE; UNCLASSIFIED DRUG;

EID: 18244409902     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-10-3916     Document Type: Article
Times cited : (96)

References (35)
  • 1
    • 0029955128 scopus 로고    scopus 로고
    • Control of ras activation
    • Downward J. Control of ras activation. Cancer Surv. 1996;27:87-100.
    • (1996) Cancer Surv , vol.27 , pp. 87-100
    • Downward, J.1
  • 2
    • 0037306522 scopus 로고    scopus 로고
    • The Ras/MAPK cascade and the control of positive selection
    • Alberola-Ila J, Hernandez-Hoyos G, The Ras/MAPK cascade and the control of positive selection. Immunol Rev. 2003;191:79-96.
    • (2003) Immunol Rev , vol.191 , pp. 79-96
    • Alberola-Ila, J.1    Hernandez-Hoyos, G.2
  • 3
    • 0038578688 scopus 로고    scopus 로고
    • GTPases and T cell activation
    • Cantrell DA. GTPases and T cell activation. Immunol Rev. 2003;192:122-130.
    • (2003) Immunol Rev , vol.192 , pp. 122-130
    • Cantrell, D.A.1
  • 4
    • 0032010114 scopus 로고    scopus 로고
    • Molecular dissection of B cell antigen receptor signaling
    • Kurosaki T. Molecular dissection of B cell antigen receptor signaling (review). Int J Mol Mod. 1998;1:515-527.
    • (1998) Int J Mol Mod , vol.1 , pp. 515-527
    • Kurosaki, T.1
  • 7
    • 0026708592 scopus 로고
    • Role of protein kinase C in T-cell antigen receptor regulation of p21ras: Evidence that two p21ras regulatory pathways coexist in T cells
    • Izquierdo M, Downward J, Graves JD, Cantrell DA. Role of protein kinase C in T-cell antigen receptor regulation of p21ras: evidence that two p21ras regulatory pathways coexist in T cells. Mol Cell Biol. 1992;12:3305-3312.
    • (1992) Mol Cell Biol , vol.12 , pp. 3305-3312
    • Izquierdo, M.1    Downward, J.2    Graves, J.D.3    Cantrell, D.A.4
  • 8
    • 0032524389 scopus 로고    scopus 로고
    • RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs
    • Ebinu JO, Bottorff DA, Chan EY, Stang SL, Dunn RJ, Stone JC. RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Science. 1998;280:1082-1086.
    • (1998) Science , vol.280 , pp. 1082-1086
    • Ebinu, J.O.1    Bottorff, D.A.2    Chan, E.Y.3    Stang, S.L.4    Dunn, R.J.5    Stone, J.C.6
  • 9
    • 0034658333 scopus 로고    scopus 로고
    • RasGRP links T-cell receptor signaling to Ras
    • Ebinu JO, Stang SL, Teixeira C, et al. RasGRP links T-cell receptor signaling to Ras. Blood. 2000;95:3199-3203.
    • (2000) Blood , vol.95 , pp. 3199-3203
    • Ebinu, J.O.1    Stang, S.L.2    Teixeira, C.3
  • 11
    • 0034061660 scopus 로고    scopus 로고
    • The guanine nucleotide exchange factor RasGRP is a high-affinity target for diacylglycerol and phorbol esters
    • Lorenzo PS, Beheshti M, Pettit GR, Stone JC, Blumberg PM. The guanine nucleotide exchange factor RasGRP is a high-affinity target for diacylglycerol and phorbol esters. Mol Pharmacol. 2000;57:840-846.
    • (2000) Mol Pharmacol , vol.57 , pp. 840-846
    • Lorenzo, P.S.1    Beheshti, M.2    Pettit, G.R.3    Stone, J.C.4    Blumberg, P.M.5
  • 12
    • 0034303371 scopus 로고    scopus 로고
    • RasGRP is essential for mouse thymocyte differentiation and TCR signaling
    • Dower NA, Stang SL, Bottorff DA, et al. RasGRP is essential for mouse thymocyte differentiation and TCR signaling. Nat Immunol. 2000;1:317-321.
    • (2000) Nat Immunol , vol.1 , pp. 317-321
    • Dower, N.A.1    Stang, S.L.2    Bottorff, D.A.3
  • 13
    • 0036848708 scopus 로고    scopus 로고
    • RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation
    • Priatel JJ, Teh SJ, Dower NA, Stone JC, Teh HS. RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation. Immunity. 2002;17:617-627.
    • (2002) Immunity , vol.17 , pp. 617-627
    • Priatel, J.J.1    Teh, S.J.2    Dower, N.A.3    Stone, J.C.4    Teh, H.S.5
  • 14
    • 0042237772 scopus 로고    scopus 로고
    • Integration of DAG signaling systems mediated by PKC-dependent phosphorylation of RasGRP3
    • Teixeira C, Stang SL, Zheng Y, Beswick NS, Stone JC. Integration of DAG signaling systems mediated by PKC-dependent phosphorylation of RasGRP3. Blood. 2003;102:1414-1420.
    • (2003) Blood , vol.102 , pp. 1414-1420
    • Teixeira, C.1    Stang, S.L.2    Zheng, Y.3    Beswick, N.S.4    Stone, J.C.5
  • 15
    • 0034671815 scopus 로고    scopus 로고
    • Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: Potential role of additional diacylglycerol binding proteins
    • Puente LG, Stone JC, Ostergaard HL. Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins. J Immunol. 2000;165:6865-6871.
    • (2000) J Immunol , vol.165 , pp. 6865-6871
    • Puente, L.G.1    Stone, J.C.2    Ostergaard, H.L.3
  • 17
    • 0025352187 scopus 로고
    • Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
    • Morgenstern JP, Land H. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 1990;18:3587-3596.
    • (1990) Nucleic Acids Res , vol.18 , pp. 3587-3596
    • Morgenstern, J.P.1    Land, H.2
  • 18
    • 3242698721 scopus 로고    scopus 로고
    • Open tubular immobilized metal ion affinity chromatography combined with MALD1 MS and MS/MS for identification of protein phosphorylation sites
    • Liu H, Stupak J, Zheng J, et al. Open tubular immobilized metal ion affinity chromatography combined with MALD1 MS and MS/MS for identification of protein phosphorylation sites. Anal Chem. 2004;76:4223-4232.
    • (2004) Anal Chem , vol.76 , pp. 4223-4232
    • Liu, H.1    Stupak, J.2    Zheng, J.3
  • 19
    • 0031014969 scopus 로고    scopus 로고
    • Rapid Ca2+-mediated activation of Rap1 in human platelets
    • Franke B, Akkerman JW, Bos JL. Rapid Ca2+-mediated activation of Rap1 in human platelets. EMBO J. 1997;16:252-259.
    • (1997) EMBO J , vol.16 , pp. 252-259
    • Franke, B.1    Akkerman, J.W.2    Bos, J.L.3
  • 20
    • 3042630992 scopus 로고    scopus 로고
    • PKC-delta associates with and is involved in the phosphorylation of RasGRPS in response to phorbol esters
    • Brodie C, Steinhart R, Kazimirsky G, et al. PKC-delta associates with and is involved in the phosphorylation of RasGRPS in response to phorbol esters. Mol Pharmacol. 2004;66:76-84.
    • (2004) Mol Pharmacol , vol.66 , pp. 76-84
    • Brodie, C.1    Steinhart, R.2    Kazimirsky, G.3
  • 21
    • 0037067713 scopus 로고    scopus 로고
    • RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs: Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function
    • Yang Y, Li L, Wong GW, et al. RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs: identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function. J Biol Chem. 2002;277:25756-25774.
    • (2002) J Biol Chem , vol.277 , pp. 25756-25774
    • Yang, Y.1    Li, L.2    Wong, G.W.3
  • 23
    • 0034682779 scopus 로고    scopus 로고
    • CaIDAG-GEFIII activation of Ras, R-Ras, and Rap1
    • Yamashita S, Mochizuki N, Ohba Y, et al. CaIDAG-GEFIII activation of Ras, R-Ras, and Rap1. J Biol Chem. 2000;275:25488-25493.
    • (2000) J Biol Chem , vol.275 , pp. 25488-25493
    • Yamashita, S.1    Mochizuki, N.2    Ohba, Y.3
  • 24
    • 0032478610 scopus 로고    scopus 로고
    • Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein Kinase C
    • Marais R, Light Y, Mason C, Paterson H, Olson MF, Marshall CJ. Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein Kinase C. Science. 1998;280:109-112.
    • (1998) Science , vol.280 , pp. 109-112
    • Marais, R.1    Light, Y.2    Mason, C.3    Paterson, H.4    Olson, M.F.5    Marshall, C.J.6
  • 25
    • 0036209077 scopus 로고    scopus 로고
    • Novel "nonkinase" phorbol ester receptors: The C1 domain connection
    • Kazanletz MG. Novel "nonkinase" phorbol ester receptors: the C1 domain connection. Mol Pharmacol. 2002;61:759-767.
    • (2002) Mol Pharmacol , vol.61 , pp. 759-767
    • Kazanletz, M.G.1
  • 26
    • 0347593996 scopus 로고    scopus 로고
    • Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling
    • Oh-hora M, Johmura S, Hashimoto A, Hikida M, Kurosaki T. Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling. J Exp Med. 2003;198:1841-1851.
    • (2003) J Exp Med , vol.198 , pp. 1841-1851
    • Oh-Hora, M.1    Johmura, S.2    Hashimoto, A.3    Hikida, M.4    Kurosaki, T.5
  • 27
    • 0029739626 scopus 로고
    • Immunodeficiency in protein kinase cbeta-deficient mice
    • Leitges M, Schmedt C, Guinamard R, et al. Immunodeficiency in protein kinase cbeta-deficient mice. Science. 1993;273:788-791.
    • (1993) Science , vol.273 , pp. 788-791
    • Leitges, M.1    Schmedt, C.2    Guinamard, R.3
  • 29
    • 0037171731 scopus 로고    scopus 로고
    • Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta
    • Miyamoto A, Nakayama K, Imaki H, et al. Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta. Nature. 2002;416:865-869.
    • (2002) Nature , vol.416 , pp. 865-869
    • Miyamoto, A.1    Nakayama, K.2    Imaki, H.3
  • 30
    • 0037143671 scopus 로고    scopus 로고
    • B-cell signaling: Protein kinase Cdelta puts the brakes on
    • Mathis D, King GL. B-cell signaling: protein kinase Cdelta puts the brakes on. Curr Biol. 2002;12:R554-R556.
    • (2002) Curr Biol , vol.12
    • Mathis, D.1    King, G.L.2
  • 31
    • 3142737230 scopus 로고    scopus 로고
    • B cell receptor-induced cAMP-response element-binding protein activation in B lymphocytes requires novel protein kinase Cdelta
    • Blois JT, Mataraza JM, Mecklenbrauker I, Tarakhovsky A, Chiles TC. B cell receptor-induced cAMP-response element-binding protein activation in B lymphocytes requires novel protein kinase Cdelta. J Biol Chem. 2004;279:30123-30132.
    • (2004) J Biol Chem , vol.279 , pp. 30123-30132
    • Blois, J.T.1    Mataraza, J.M.2    Mecklenbrauker, I.3    Tarakhovsky, A.4    Chiles, T.C.5
  • 32
    • 9344264018 scopus 로고    scopus 로고
    • Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation
    • Aiba Y, Oh-hora M, Kiyonaka S, et al. Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation. Proc Natl Acad Sci U SA. 2004;101:16612-16617.
    • (2004) Proc Natl Acad Sci U SA , vol.101 , pp. 16612-16617
    • Aiba, Y.1    Oh-Hora, M.2    Kiyonaka, S.3
  • 33
    • 0029935183 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1
    • Porfiri E, McCormick F. Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1. J Biol Chem. 1996;271:5871-5877.
    • (1996) J Biol Chem , vol.271 , pp. 5871-5877
    • Porfiri, E.1    McCormick, F.2
  • 34
    • 0037631371 scopus 로고    scopus 로고
    • Phosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortex
    • Yang H, Cooley D, Legakis JE, Ge Q, Andrade R, Mattingly RR. Phosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortex. J Biol Chem. 2003;278:13278-13285.
    • (2003) J Biol Chem , vol.278 , pp. 13278-13285
    • Yang, H.1    Cooley, D.2    Legakis, J.E.3    Ge, Q.4    Andrade, R.5    Mattingly, R.R.6
  • 35
    • 2442683012 scopus 로고    scopus 로고
    • Rap2B-dependent stimulation of phospholipase C-epsilon by epidermal growth factor receptor mediated by c-Src phosphorylation of RasGRP3
    • Slope MB, Vom Dorp F, Szatkowski D, et al. Rap2B-dependent stimulation of phospholipase C-epsilon by epidermal growth factor receptor mediated by c-Src phosphorylation of RasGRP3. Mol Cell Biol. 2004;24:4664-4676.
    • (2004) Mol Cell Biol , vol.24 , pp. 4664-4676
    • Slope, M.B.1    Vom Dorp, F.2    Szatkowski, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.