Modulation of heme and myristate binding to human serum albumin by anti-HIV drugs: An optical and NMR spectroscopic study

FEBS Journal

Volumn 274, Issue 17, 2007, Pages 4491-4502

  Fanali, Gabriella ^a   Bocedi, Alessio ^b,c,d   Ascenzi, Paolo ^b,c   Fasano, Mauro ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^c ROMA TRE UNIVERSITY   (Italy)

^d IRBM   (Italy)

Author keywords

Allosteric modulation; Anti HIV drugs; Heterotropic interactions; Human serum albumin; NMR relaxation

Indexed keywords

ABACAVIR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ATAZANAVIR; FERRIC ION; HEME; MYRISTIC ACID; NEVIRAPINE; SERUM ALBUMIN;

ARTICLE; BINDING AFFINITY; DISPERSION; DISSOCIATION; DRUG BINDING SITE; DRUG PROTEIN BINDING; DRUG STRUCTURE; EQUILIBRIUM CONSTANT; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SIMULATION;

HEME; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MYRISTIC ACID; REVERSE TRANSCRIPTASE INHIBITORS; SERUM ALBUMIN;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 34548138940     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.05978.x     Document Type: Article

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