Simultaneous determination of the antiretroviral agents: Amprenavir, lopinavir, ritonavir, saquinavir and efavirenz in human peripheral blood mononuclear cells by high-performance liquid chromatography-mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 813, Issue 1-2, 2004, Pages 209-216

  Rouzes, Agnès ^a   Berthoin, Karine ^a   Xuereb, Fabien ^a   Djabarouti, Sarah ^a   Pellegrin, Isabelle ^b   Pellegrin, Jean Luc ^c   Coupet, Anne Cécile ^a   Augagneur, Sylvie ^a   Budzinski, Hélène ^a   Saux, Marie Claude ^a   Breilh, Dominique ^a,d  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b HÔPITAL PELLEGRIN   (France)

^c HAUT LÉVÊQUE HOSPITAL   (France)

^d Lab Pharmacocinetique Pharm Clin   (France)

Author keywords

Intra cellular quantitation; LC MS; Non nucleoside reverse transcriptase inhibitor (NNRTI); Protease inhibitors (PIs)

Indexed keywords

ANTIRETROVIRAL AGENTS; LOPINAVIR (LPV); PROTEASE INHIBITORS (PI);

ASSAYS; BLOOD; CELLS; CONCENTRATION (PROCESS); EXTRACTION;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

AMPRENAVIR; ANTIRETROVIRUS AGENT; EFAVIRENZ; LOPINAVIR; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR;

ACCURACY; ARTICLE; CALIBRATION; CELL LEVEL; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG MONITORING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROCESS DEVELOPMENT; QUANTITATIVE ANALYSIS; VALIDATION PROCESS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HIV PROTEASE INHIBITORS; HUMANS; LEUKOCYTES, MONONUCLEAR; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 8844219735     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2004.09.041     Document Type: Article

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