Quantitative analysis of allosteric drug-protein binding by biointeraction chromatography

Nature Biotechnology

Volumn 22, Issue 11, 2004, Pages 1445-1448

  Chen, Jianzhong ^a   Hage, David S ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOPOLYMERS; BLOOD; DRUG PRODUCTS; PROTEINS;

ALLOSTERIC INTERACTIONS; BINDING AGENTS; HUMAN SERUM ALBUMIN (HSB);

DRUG INTERACTIONS;

HUMAN SERUM ALBUMIN; IBUPROFEN; LORAZEPAM; OXAZEPAM; PHENYTOIN; TRYPTOPHAN;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; CHROMATOGRAPHY; DRUG PROTEIN BINDING; MATHEMATICAL COMPUTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; QUANTITATIVE ANALYSIS;

ALLOSTERIC SITE; BINDING SITES; BIOLOGICAL ASSAY; CHROMATOGRAPHY, AFFINITY; DRUG DELIVERY SYSTEMS; DRUG DESIGN; IBUPROFEN; OXAZEPAM; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SERUM ALBUMIN; STEREOISOMERISM; TRYPTOPHAN;

EID: 8344226902     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt1022     Document Type: Article

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