Crystal structure analysis of warfarin binding to human serum albumin. Anatomy of drug site I

Journal of Biological Chemistry

Volumn 276, Issue 25, 2001, Pages 22804-22809

  Petitpas, Isabelle ^a   Bhattacharya, Ananyo A ^c   Twine, Sue ^b   East, Malcolm ^b   Curry, Stephen ^d  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c BURNHAM INSTITUTE   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CONFORMATIONS; CRYSTAL STRUCTURE; DRUG PRODUCTS; FATTY ACIDS; ISOMERS; PROTEINS; STEREOCHEMISTRY;

HUMAN SERUM ALBUMIN;

BIOCHEMISTRY;

FATTY ACID; HUMAN SERUM ALBUMIN; WARFARIN; ALBUMINOID; MYRISTIC ACID;

ARTICLE; BINDING SITE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; ENANTIOMER; HUMAN; MOLECULAR INTERACTION; PRIORITY JOURNAL; STEREOISOMERISM; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

ALBUMINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MYRISTIC ACID; PROTEIN BINDING; PROTEIN CONFORMATION; STEREOISOMERISM; WARFARIN;

EID: 0035933789     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100575200     Document Type: Article

References (38)

1. Peters, T. (1995) All about Albumin: Biochemistry, Genetics, and Medical Applications, Academic Press, San Diego
2. Kragh-Hansen, U. (1990) Dan. Med. Bull. 37, 57-84
3. Carter, D. C., and Ho, J. X. (1994) Adv. Protein Chem. 45, 152-203
4. Holford, N. H. G., and Benet, L. Z. (1998) in Basic and Clinical Pharmacology (Katzung, B. G., ed) 7th Ed., pp. 34-49, Appleton and Lange, Stamford, CT
5. Lindup, W. E. (1987) in Progress in Drug Metabolism (Bridges, J. W., Chasseaud, L. F., and Gibson, G. G., eds) Vol. 10, pp. 141-185, Taylor & Francis, London
6. Petersen, C. E., Ha, C. E., Harohalli, K., Park, D. S., and Bhagavan, N. V. (2000) Chem. Biol. Interact. 124, 161-172
7. Wilding, G., Blumberg, E. S., and Vesell, E. S. (1977) Science 195, 991-994
8. Beljaars, L., Molema, G., Schuppan, D., Geerts, A., De Bleser, P. J., Weert, B., Meijer, D. K., and Poelstra, K. (2000) J. Biol. Chem. 275, 12743-12751
9. Tsuchida, E., Komatsu, T., Hamamatsu, K., Matsukawa, Y., Tajima, A., Yoshizu, A., Izumi, Y., and Kobayashi, K. (2000) Bioconjugate Chem. 11, 46-50
10. He, X. M., and Carter, D. C. (1992) Nature 358, 209-215
11. Curry, S., Mandelkow, H., Brick, P., and Franks, N. (1998) Nat. Struct. Biol. 5, 827-835
12. Bhattacharya, A. A., Grüne, T., and Curry, S. (2000) J. Mol. Biol. 303, 721-732
13. Sudlow, G., Birkett, D. J., and Wade, D. N. (1975) Mol. Pharmacol. 11, 824-832
14. Sjoholm, I., Ekman, B., Kober, A., Ljungstedt-Pahlman, I., Seiving, B., and Sjodin, T. (1979) Mol. Pharmacol. 16, 767-777
15. Bhattacharya, A. A., Curry, S., and Franks, N. P. (2000) J. Biol. Chem. 275, 38731-38738
16. Fehske, K. J., Schläfer, U., Wollert, U., and Müller, W. E. (1981) Mol. Pharmacol. 21, 387-393
17. Kragh-Hansen, U. (1988) Mol. Pharmacol. 34, 160-171
18. Yamasaki, K., Maruyama, T., Kragh-Hansen, U., and Otagiri, M. (1996) Biochim. Biophys. Acta 1295, 147-157
19. Ho, J. X., Holowachuk, E. W., Norton, E. J., Twigg, P. D., and Carter, D. C. (1993) Eur. J. Biochem. 215, 205-212
20. Diana, F. J., Veronich, K., and Kapoor, A. L. (1989) J. Pharm. Sci. 78, 195-199
21. Loun, B., and Hage, D. S. (1994) Anal. Chem. 66, 3814-3822
22. Vorum, H., and Honoré, B. (1996) J. Pharm. Pharmacol. 48, 870-875
23. Birkett, D. J., Myers, S. P., and Sudlow, G. (1977) Mol. Pharmacol. 13, 987-992
24. Wilting, J., van der Giesen, W. F., Janssen, L. H., Weideman, M. M., Otagiri, M., and Perrin, J. H. (1980) J. Biol. Chem. 255, 3032-3037
25. Wanwimolruk, S., and Birkett, D. J. (1982) Biochim. Biophys. Acta 709, 247-255
26. West, B. D., Preis, S., Schroeder, C. H., and Link, K. P. (1961) J. Am. Chem. Soc. 83, 2676-2679
27. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 905-921
28. Esnouf, R. (1997) J. Mol. Graph. 15, 133-138
29. Merrit, E. A., and Bacon, D. J. (1997) Methods Enzymol. 277, 505-524
30. Carter, D. C., Chang, B., Ho, J. X., Keeling, K., and Krishnasami, Z. (1994) Eur. J. Biochem. 226, 1049-1052
31. Valente, E. J., Lingafelter, E. C., Porter, W. R., and Trager, W. F. (1977) J. Med. Chem. 20, 1489-1493
32. Bos, O. J., Remijn, J. P., Fischer, M. J., Wilting, J., and Janssen, L. H. (1988) Biochem. Pharmacol. 37, 3905-3909
33. Fehske, K. J., Muller, W. E., Wollert, U., and Velden, L. M. (1979) Mol. Pharmacol. 16, 778-789
34. Sudlow, G., Birkett, D. J., and Wade, D. N. (1976) Mol. Pharmacol. 12, 1052-1061
35. Dockal, M., Chang, M., Carter, D. C., and Ruker, F. (2000) Protein Sci. 9, 1455-1465
36. Curry, S., Brick, P., and Franks, N. P. (1999) Biochim. Biophys. Acta 1441, 131-140
37. Mao, H., Gunasekera, A. H., and Fesik, S. W. (2000) Protein Expression Purif. 20, 492-499
38. Nicholls, A., Sharp, K. A., and Honig, B. (1991) Proteins 11, 281-296