Location of High and Low Affinity Fatty Acid Binding Sites on Human Serum Albumin Revealed by NMR Drug-competition Analysis

Journal of Molecular Biology

Volumn 361, Issue 2, 2006, Pages 336-351

  Simard, Jeffrey R ^a   Zunszain, Patricia A ^b   Hamilton, James A ^a   Curry, Stephen ^b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

binding sites; fatty acids; HSA; NMR

Indexed keywords

CARBON 13; CARBOXYL GROUP; DIAZEPAM; FATTY ACID; HEMIN; HUMAN SERUM ALBUMIN; LIGAND; LONG CHAIN FATTY ACID; PALMITIC ACID; PHENYLBUTAZONE; PROPOFOL;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL INTERACTION; CRYSTALLOGRAPHY; DRUG COMPETITION; DRUG PROTEIN BINDING; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 33746253976     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.06.028     Document Type: Article

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