Allosteric modulation of myristate and Mn(III)heme binding to human serum albumin: Optical and NMR spectroscopy characterization

FEBS Journal

Volumn 272, Issue 18, 2005, Pages 4672-4683

  Fanali, Gabriella ^a   Fesce, Riccardo ^a   Agrati, Cristina ^a   Ascenzi, Paolo ^b,c   Fasano, Mauro ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b ROMA TRE UNIVERSITY   (Italy)

^c NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

Author keywords

Allostery; Fatty acid binding; Heme binding; Human serum albumin; NMR relaxation

Indexed keywords

FATTY ACID; HEME; HUMAN SERUM ALBUMIN; MANGANESE; MYRISTIC ACID;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATION; HUMAN; LIGAND BINDING; MODULATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLARIMETRY; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; BINDING SITES; HEMATOPORPHYRINS; HUMANS; HYDROGEN-ION CONCENTRATION; METALLOPORPHYRINS; MYRISTIC ACID; PROTEIN BINDING; PROTEIN CONFORMATION; SERUM ALBUMIN; SPECTRUM ANALYSIS; WATER;

EID: 25444527458     PISSN: 1742464X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2005.04883.x     Document Type: Article

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