p53 response to arsenic exposure in epithelial cells: Protein kinase B/Akt involvement

Toxicological Sciences

Volumn 99, Issue 1, 2007, Pages 126-140

  Sandoval, Marisol ^a   Morales, Moisés ^a   Tapia, Rocío ^a   Alarcón, Luz del Carmen ^b   Sordo, Montserrat ^c   Ostrosky Wegman, Patricia ^c   Ortega, Arturo ^a   López Bayghen, Esther ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b UNIVERSIDAD AUTÓNOMA DE GUERRERO   (Mexico)

^c INSTITUTO DE INVESTIGACIONES BIOMÉDICAS   (Mexico)

Author keywords

Akt; Arsenic; Human keratinocytes; p53 protein; Protein kinase B

Indexed keywords

ARSENIC; ARSENITE SODIUM; CALCIUM ION; DIACYLGLYCEROL KINASE; DNA; GLYCOGEN SYNTHASE KINASE; GLYCOGEN SYNTHASE KINASE 3 BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; UNCLASSIFIED DRUG;

ARSENIC POISONING; ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRESS; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; KERATINOCYTE; NEWBORN; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ADENOCARCINOMA; ARSENITES; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; CYTOCHALASIN B; DNA DAMAGE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; ENVIRONMENTAL POLLUTANTS; ENZYME INHIBITORS; EPITHELIAL CELLS; FEMALE; HELA CELLS; HUMANS; INFANT, NEWBORN; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SODIUM COMPOUNDS; TUMOR SUPPRESSOR PROTEIN P53; UTERINE CERVICAL NEOPLASMS;

EID: 34547895455     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm153     Document Type: Article

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