Comparison of l-monosodium glutamate and l-amino acid taste in rats

Neuroscience

Volumn 148, Issue 1, 2007, Pages 266-278

  Delay, E R ^a,b   Mitzelfelt, J D ^b   Westburg, A M ^b   Gross, N ^b   Duran, B L ^b   Eschle, B K ^a  

^a UNIVERSITY OF VERMONT   (United States)

^b REGIS UNIVERSITY   (United States)

Author keywords

animal psychophysics; glycine; l arginine; l proline; l serine; thresholds

Indexed keywords

AMILORIDE; AMINO ACID; ARGININE; GLUTAMATE RECEPTOR; GLUTAMATE SODIUM; GLYCINE; HETERODIMER; PROLINE; SERINE; SODIUM; SODIUM CHANNEL BLOCKING AGENT; SUCROSE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PSYCHOPHYSICS; RAT; SIGNAL TRANSDUCTION; STIMULUS; SWEETNESS; TASTE; TASTE ACUITY; TASTE AVERSION; TASTE BUD; TASTE DISCRIMINATION; TASTE DISCRIMINATION METHOD; TASTE PREFERENCE; TECHNIQUE;

AMINO ACIDS; ANIMALS; ARGININE; AVOIDANCE LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCINE; ISOMERISM; MALE; PERCEPTION; PROLINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; SERINE; SIGNAL TRANSDUCTION; SODIUM GLUTAMATE; TASTE; TASTE BUDS; TASTE THRESHOLD; VISCERAL AFFERENTS;

EID: 34547691442     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2007.05.045     Document Type: Article

References (40)

1. Abaffy T., Trubey K.R., and Chaudhari N. Adenylyl cyclase expression and modulation of cAMP in rat taste cells. Am J Physiol Cell Physiol 284 (2003) C1420-C1428
2. Bellisle F. Glutamate and the UMAMI taste: sensory metabolic, nutritional and behavioural considerations. A review of the literature published in the last 10 years. Neurosci Biobehav Rev 23 (1999) 423-438
3. Brosvic G.M., and Slotnick B.M. Absolute and intensity-difference taste thresholds in the rat: Evaluation of an automated multi-channel gustometer. Physiol Behav 38 (1986) 711-717
4. Caicedo A., and Roper S.D. Taste receptor cells that discriminate between bitter stimuli. Science 291 (2001) 1465-1466
5. Chaudhari N., Landin A.M., and Roper S.D. A metabotropic glutamate receptor variant functions as a taste receptor. Nat Neurosci 3 (2000) 113-119
6. Chaudhari N., Yang H., Lamp C., Delay E., Cartford C., Than T., and Roper S. The taste of monosodium glutamate: membrane receptors in taste buds. J Neurosci 16 (1996) 3817-3826
7. Cui M., Jiang P., Maillet E., Max M., Margolskee R.F., and Osman R. The heterodimeric sweet taste receptor has multiple potential ligand binding sites. Curr Pharm Des 12 (2006) 4591-4600
8. Curtis K.S., and Contreras R.J. Sex differences in electrophysiological and behavioral responses to NaCl taste. Behav Neurosci 120 (2006) 917-924
9. Curtis K.S., Davis L.M., Johnson A.L., Therrien K.L., and Contreras R.J. Sex differences in behavioral taste responses to and ingestion of sucrose and NaCl solutions by rats. Physiol Behav 80 (2004) 657-664
10. Delay E.R., Hernandez N.P., Bromley K., and Margolskee R.F. Sucrose and monosodium glutamate taste thresholds and discrimination ability of T1R3 knockout mice. Chem Senses 31 (2006) 351-357
11. Delay E.R., Sewczak G.M., Stapleton J.R., and Roper S.D. Glutamate taste: discrimination between the tastes of glutamate agonists and monosodium glutamate in rats. Chem Senses 29 (2004) 291-299
12. Eylam S., and Spector A.C. Oral amiloride treatment decreases taste sensitivity to sodium salts in C57BL/6J and DBA2J mice. Chem Senses 28 (2003) 447-458
13. Formaker B.K., Kearns C.E., and Frank M.E. The taste of polycose in hamsters. Chem Senses 23 (1998) 675-682
14. Frank M.E., Formaker B.K., and Hettinger T.P. Taste responses to mixtures: analytic processing of quality. Behav Neurosci 117 (2003) 228-235
15. Geran L.C., and Spector A.C. Amiloride increases sodium chloride taste detection threshold in rats. Behav Neurosci 114 (2000) 623-634
16. Harada S., Marui T., and Kasahara Y. Neural and behavioral responses to amino acids in mice and rats. Annals N Y Acad Sci 510 (1987) 345-346
17. He W., Yasumatsu K., Varadarajan V., Yamada A., Lem J., Ninomiya Y., Margolskee R.F., and Damak S. Umami taste responses are mediated by alpha-transducin and alpha-gustducin. J Neurosci 24 (2004) 7674-7680
18. Heyer B.R., Taylor-Burds C.C., Tran L.H., and Delay E.R. Monosodium glutamate and sweet taste: generalization of conditioned taste aversion between glutamate and sweet stimuli in rats. Chem Senses 28 (2003) 631-641
19. Heyer B.R., Taylor-Burds C.C., Mitzelfelt J.D., and Delay E.R. Monosodium glutamate and sweet taste: discrimination between the tastes of sweet stimuli and glutamate in rats. Chem Senses 29 (2004) 721-729
20. th ed. (1997), Wadsworth Publishing Company, Belmont, CA
21. Iwasaki K., Kassahara T., and Sato M. Gustatory effectiveness of amino acids in mice: behavioral and neurophysiological studies. Physiol Behav 34 (1985) 531-542
22. Kasahara T., Iwasaki K., and Sato M. Taste effectiveness of some D- and L-amino acids in mice. Physiol Behav 39 (1987) 619-624
23. Li X., Staszewski L., Xu H., Durick K., Zoller M., and Adler E. Human receptors for sweet and umami taste. Proc Natl Acad Sci U S A 99 (2002) 4692-4696
24. Maga J.A. Flavor potentiators. CRC Crit Rev Food Sci Nutr 18 (1983) 231-312
25. Manita S., Bachmanov A.A., Li X., Beauchamp G.K., and Inoue M. Is glycine "sweet" to mice?. Mouse strain differences in perception of glycine taste. Chem Senses 31 (2006) 785-793
26. Markison S., and Spector A.C. Amiloride is an ineffective conditioned stimulus in taste aversion learning. Chem Senses 20 (1995) 559-563
27. Maruyama Y., Pereira E., Margolskee R.F., Chaudhari N., and Roper S.D. Umami responses in mouse taste cells indicate more than one receptor. J Neurosci 26 (2006) 2227-2234
28. Morini G., Bassoli A., and Temussi P.A. From small sweeteners to sweet proteins: anatomy of the binding sites of the human T1R2_T1R3 receptor. J Med Chem 48 (2005) 5520-5529
29. Nelson G., Chandrashekar J., Hoon M.A., Feng L., Zhao G., Ryba N.J.P., and Zuker C.S. An amino-acid taste receptor. Nature 416 6877 (2002) 199-202
30. Ninomiya Y., and Funakoshi M. Behavioural discrimination between glutamate and the four basic taste substances in mice. Comp Biochem Physiol 92A (1989) 365-370
31. Ninomiya Y., Nakashima K., Fukuda A., Nishino H., Sugimura T., Hino A., Danilova V., and Hellekant G. Responses to umami substances in taste bud cells innervated by the chorda tympani and glossopharyngeal nerves. J Nutr 130 (2000) 950S-953S
32. Pritchard T.C., and Scott T.R. Amino acids as taste stimuli. I. Neural and behavioral attributes. Brain Res 253 (1982) 81-92
33. Ruiz C., Gutknecht S., Delay E., and Kinnamon S. Detection of NaCl and KCl in TRPV1 knockout mice. Chem Senses 31 (2006) 813-820
34. Schiffman S.S., Sennewald K., and Gagnon J. Comparison of taste qualities and thresholds of D- and L-amino acids. Physiol Behav 27 (1981) 51-59
35. Spector A.C., and Kopka S.L. Rats fail to discriminate quinine from denatonium: implications for the neural coding of bitter-tasting compounds. J Neurosci 22 (2002) 1937-1941
36. Stapleton J.R., Roper S.D., and Delay E.R. The taste of monosodium glutamate (MSG), L-aspartic acid, and N-methyl-D-aspartate (NMDA) in rats: are NMDA receptors involved in MSG taste?. Chem Senses 24 (1999) 449-457
37. Stapleton J.R., Luellig M., Roper S.D., and Delay E.R. Discrimination between the tastes of sucrose and monosodium glutamate in rats. Chem Senses 27 (2002) 375-382
38. Taylor-Burds C.C., Westburg ÄM., Wifall T.C., and Delay E.R. Behavioral comparisons of the tastes of L-alanine and monosodium glutamate in rats. Chem Senses 29 (2004) 807-814
39. Yamamoto T., Matsuo R., Fujimoto Y., Fukunaga I., Miyasaka A., and Imoto T. Electrophysiological and behavioral studies on the taste of umami substances in the rat. Physiol Behav 49 (1991) 919-925
40. Zhao G.Q., Zhang Y., Hoon M.A., Chandrashekar J., Erienbach I., Ryba N.J.P., and Zuker C.S. The receptors for mammalian sweet and umami taste. Cell 115 (2003) 255-266