Thrombomodulin changes the molecular surface of interaction and the rate of complex formation between thrombin and protein C

Journal of Biological Chemistry

Volumn 280, Issue 9, 2005, Pages 7956-7961

  Xu, Hong ^a   Bush, Leslie A ^a   Pineda, Agustin O ^a   Caccia, Sonia ^b   Di Cera, Enrico ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; BINDING ENERGY; COAGULATION; DIFFUSION; MOLECULAR BIOLOGY; REACTION KINETICS;

ACTIVE SITES; EPITOPES; MOLECULAR SURFACES; THROMBOMODULIN;

PROTEINS;

ARGININE; ASPARTIC ACID; EPITOPE; GLYCINE; LYSINE; PHENYLALANINE; PROLINE; PROTEIN C; SODIUM ION; THREONINE; THROMBIN; THROMBOMODULIN; TYROSINE;

ARTICLE; BINDING AFFINITY; BINDING SITE; DIFFUSION; KINETICS; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TEMPERATURE;

ALANINE; ASPARTIC ACID; BINDING SITES; BIOCHEMISTRY; EPITOPES; HUMANS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PEPTIDES; PROTEIN BINDING; PROTEIN C; PROTEIN CONFORMATION; RECEPTORS, THROMBIN; SODIUM; TEMPERATURE; THROMBIN; THROMBOMODULIN; TYROSINE;

EID: 14844331743     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412869200     Document Type: Article

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