A specific subdomain in φ29 DNA polymerase confers both processivity and strand-displacement capacity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 18, 2005, Pages 6407-6412

  Rodríguez, Irene ^a   Lázaro, José M ^a   Blanco, Luis ^a   Kamtekar, Satwik ^b   Berman, Andrea J ^b   Wang, Jimin ^b   Steitz, Thomas A ^b   Salas, Margarita ^a   De Vega, Miguel ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b YALE UNIVERSITY   (United States)

Author keywords

DNA binding stability; Helicase like activity; Protein primed replication; Terminal protein region

Indexed keywords

ASPARTIC ACID; DNA POLYMERASE; EXONUCLEASE; GLUTAMIC ACID; HELICASE; DNA; DNA DIRECTED DNA POLYMERASE; EXODEOXYRIBONUCLEASE; PRIMER DNA;

AMINO ACID SEQUENCE; ARTICLE; CRYSTALLOGRAPHY; DELETION MUTANT; DNA BINDING; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVITY; GENE INSERTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INTERACTION; TETRATRICOPEPTIDE REPEAT; BACTERIOPHAGE T4; CHEMICAL STRUCTURE; COMPARATIVE STUDY; DNA TEMPLATE; GEL MOBILITY SHIFT ASSAY; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BACTERIOPHAGE T4; DNA; DNA PRIMERS; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EXODEOXYRIBONUCLEASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; TEMPLATES, GENETIC;

EID: 18144365195     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0500597102     Document Type: Article

References (40)

1. Kornberg, A. & Baker, T. (1992) DNA Replication (Freeman, San Francisco), 2nd Ed.
2. Watson, J. D., Baker, T. A., Bell, S. P., Gann, A., Levine, M. & Losick, R. (2004) Molecular Biology of the Gene (Cold Spring Harbor Lab. Press, Plainview, NY), 5th Ed.
3. Braithwaite, D. K. & Ito, J. (1993) Nucleic Acids Res. 21, 787-802.
4. Esteban, J. A., Salas, M. & Blanco, L. (1993) J. Biol. Chem. 268, 2719-2726.
5. Garmendia, C., Bernad, A., Esteban, J.A., Blanco, L. & Salas, M. (1992) J. Biol. Chem. 267, 2594-2599.
6. Blanco, L. & Salas, M. (1995) Methods Enzymol. 262, 283-294.
7. Blanco, L. & Salas, M. (1996) J. Biol. Chem. 271, 8509-8512.
8. Salas, M. (1991) Annu. Rev. Biochem. 60, 39-71.
9. Salas, M., Miller, J. T., Leis, J. & DePamphilis, M. L. (1996) in DNA Replication in Eukaryotic Cells, ed. DePamphilis, M. L. (Cold Spring Harbor Lab. Press, Plainview, NY), pp. 131-176.
10. Salas, M. (1999) in Genetic Engineering, ed. Setlow, J. K. (Kluwer Academic/Plenum, New York), Vol. 21, pp. 159-171.
11. Blanco, L., Bernad, A., Lázare, J. M., Martín, G., Garmendia, C. & Salas, M. (1989) J. Biol. Chem. 264, 8935-8940.
12. Huber, H. E., Tabor, S. & Richardson, C.C. (1987) J. Biol. Chem. 262, 16224-16232.
13. Tabor, S., Huber, H. E. & Richardson, C. C. (1987) J. Biol. Chem. 262, 16212-16223.
14. Kong, X. P., Onrust, R., O'Donnell, M. & Kuriyan, J. (1992) Cell 69, 425-437.
15. Jonnson, Z. O. & Hübscher, U. (1997) BioEssays 19, 967-975.
16. Kelman, Z. (1997) Oncogene 14, 629-640,
17. Dean, F. B., Nelson, J. R., Giesler, T. L. & Lasken, R. S. (2001) Genome Res. 11, 1095-1099.
18. Dean, F. B., Hosono, S., Fang, L., Wu, X., Faruqi, A. F., Bray-Ward, P., Sun, Z., Zong, Q., Du, Y., Du, J., et al. (2002) Proc. Natl. Acad. Sci. USA 99, 5261-5266.
19. Kamtekar, S., Berman, A.J., Wang, J., Lázaro, J. M., de Vega, M., Blanco, L., Salas, M. & Steitz, T. A. (2004) Mol. Cell 16, 609-618.
20. Wang, J., Sattar, A. K., Wang, C. C., Karam, J. D., Konigsberg, W. H. & Steitz, T. A. (1997) Cell 89, 1087-1099.
21. Hopfner, K. P., Eichinger, A., Engh, R., Laue, F., Ankanbauer, W., Huber, R. & Angerer, B. (1999) Proc. Natl. Acad. Sci. USA 96, 3600-3605.
22. Hashimoto, H., Nishioka, M., Fujiwara, S., Takagi, M., Imanaka, T., Inoue, T. & Kai, Y. (2001) J. Mol. Biol. 306, 469-477.
23. Rodriguez, A. C., Park, H., Mao, C. & Beese, L. (2000) J. Mol. Biol. 299, 447-462.
24. Zhao, Y., Jeruzalmi, D., Moarefi, I., Leighton, L., Lasken, R. & Kuriyan, J. (1999) Structure (Cambridge, U.K.) 7, 1189-1199.
25. Dufour, E., Méndez, J., Lázaro, J. M., de Vega, M., Blanco, L. & Salas, M. (2000) J. Mol. Biol. 304, 289-300.
26. Blasco, M. A., Blanco, L., Pares, E., Salas, M. & Bernad, A. (1990) Nucleic Acids Res. 18, 4763-4770.
27. Dufour, E., Rodríguez, I., Lázaro, J.M., Salas, M. & de Vega, M. (2003) J. Mol. Biol. 331, 781-794.
28. Franklin, M., Wang, J. & Steitz, T. A. (2001) Cell 105, 657-667.
29. Lázaro, J. M., Blanco, L. & Salas, M. (1995) Methods Enzymol. 262, 42-49.
30. Carthew, R. W., Chodosch, L. A. & Sharp, P. A. (1985) Cell 43, 439-448.
31. Méndez, J., Blanco, L., Lázaro, J. M. & Salas, M. (1994) J. Biol. Chem. 269, 30030-30038.
32. Doublié, S., Tabor, S., Long, A., Richardson, C. & Ellenberger, T. (1998) Nature 391, 251-258.
33. Li, Y., Korolev, S. & Waksman, G. (1998) EMBO J. 17, 7514-7525.
34. Cannistraro, V. J. & Taylor, J. S. (2004) J. Biol. Chem. 219, 18288-18295.
35. Krishna, T. A., Kong, X. P., Gary, S., Burgers, M. & Kuriyan, J. (1994) Cell 79, 1233-1243.
36. Shamoo, Y. & Steitz, T. A. (1999) Cell 99, 155-166.
37. Miyata, T., Oyama, T., Mayanagi, K., Ishino, S., Ishino, Y. & Morikawa, K. (2004) Nat. Struct. Mol. Biol. 11, 632-636.
38. Bowman, G. D., O'Donnell, M. & Kuriyan, J. (2004) Nature 429, 724-730.
39. Cheetham, G. M., Jeruzalmi, D. & Steitz, T. A. (1999) Nature 399, 80-83.
40. Butcher, S. J., Grimes, J. M., Makeyev, E. V., Bamford, D. H. & Stuart, D. I. (2001) Nature 410, 235-240.