Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo

Journal of Biological Chemistry

Volumn 282, Issue 33, 2007, Pages 23910-23918

  Mammoto, Tadanori ^a   Parikh, Samir M ^a   Mammoto, Akiko ^b   Gallagher, Diana ^a   Chan, Barden ^a   Mostoslavsky, Gustavo ^c   Ingber, Donald E ^b   Sukhatme, Vikas P ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD INSTITUTES OF MEDICINE   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; ENZYME INHIBITION; PHOSPHORYLATION;

ENDOTHELIUM; REGULATORY PROTEINS; VESSEL-SEALING EFFECTS;

LIGANDS;

ANGIOPOIETIN 1; ANGIOPOIETIN RECEPTOR; CYTOSKELETON PROTEIN; ENDOTOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P190; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG INHIBITION; ENDOTHELIUM CELL; ENDOTOXEMIA; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANGIOPOIETIN-1; ANIMALS; CAPILLARY PERMEABILITY; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GTPASE-ACTIVATING PROTEINS; HUMANS; MICE; PHOSPHORYLATION; RAC1 GTP-BINDING PROTEIN; RECEPTOR, TIE-2; RHOA GTP-BINDING PROTEIN;

MUS;

EID: 34447627607     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M702169200     Document Type: Article

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