Acute alcohol intoxication increases interleukin-18-mediated neutrophil infiltration and lung inflammation following burn injury in rats

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 292, Issue 5, 2007, Pages

  Li, Xiaoling ^a   Kovacs, Elizabeth J ^b   Schwacha, Martin G ^a   Chaudry, Irshad H ^a   Choudhry, Mashkoor A ^a,c  

^a Kentucky   (United States)

^b LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

Author keywords

Adhesion molecule; Chemokines; Inflammatory mediators

Indexed keywords

ALCOHOL; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 1; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 3; GRANULOCYTE ANTIBODY; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 18; INTERLEUKIN 18 ANTIBODY; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; MYELOPEROXIDASE; UNCLASSIFIED DRUG; WATER;

ALCOHOL BLOOD LEVEL; ALCOHOL INTOXICATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BODY SURFACE; BURN; COMPARATIVE STUDY; CYTOKINE PRODUCTION; DEPLETION; ENZYME ACTIVITY; LUNG EDEMA; LUNG PARENCHYMA; MALE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; UPREGULATION; WATER CONTENT;

ALCOHOLIC INTOXICATION; ANIMALS; BURNS; DISEASE MODELS, ANIMAL; EDEMA; ETHANOL; INFLAMMATION; INTERLEUKIN-18; LUNG; MALE; NEUTROPHILS; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 34447561568     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00408.2006     Document Type: Article

References (61)

1. Alexander M, Chaudry IH, Schwacha MG. Relationships between burn size, immunosuppression, and macrophage hyperactivity in a murine model of thermal injury. Cell Immunol 220: 63-69, 2002.
2. Brown LA, Cook RT, Jerrells TR, Kolls JK, Nagy LE, Szabo G, Wands JR, Kovacs EJ. Acute and chronic alcohol abuse modulate immunity. Alcohol Clin Exp Res 30: 1624-1631, 2006.
3. Carrico CJ, Holcomb JB, Chaudry IH. Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: report of the PULSE Trauma Work Group. Post Resuscitative and Initial Utility of Life Saving Efforts. Shock 17: 165-168, 2002.
4. Choudhry MA, Fazal N, Goto M, Gamelli RL, Sayeed MM. Gut-associated lymphoid T cell suppression enhances bacterial translocation in alcohol and burn injury. Am J Physiol Gastrointest Liver Physiol 282: G937-G947, 2002.
5. Choudhry MA, Gamelli RL, Chaudry IH. Alcohol abuse: a major contributing factor to post-burn/trauma immune complications. In: 2004 Yearbook of Intensive Care and Emergency Medicine, edited by Vincent J.-L. New York: Springer, 2004, p. 15-26.
6. Choudhry MA, Rana SN, Kavanaugh MJ, Kovacs EJ, Gamelli RL, Sayeed MM. Impaired intestinal immunity and barrier function: a cause for enhanced bacterial translocation in alcohol intoxication and burn injury. Alcohol 33: 199-208, 2004.
7. Church D, Elsayed S, Reid O, Winston B, Lindsay R. Burn wound infections. Clin Microbiol Rev 19: 403-434, 2006.
8. Cox RA, Burke AS, Soejima K, Murakami K, Katahira J, Traber LD, Herndon DN, Schmalstieg FC, Traber DL, Hawkins HK. Airway obstruction in sheep with burn and smoke inhalation injuries. Am J Respir Cell Mol Biol 29: 295-302, 2003.
9. Dinarello CA, Fantuzzi G. Interleukin-18 and host defense against infection. J Infect Dis 187, Suppl 2: S370-S384, 2003.
10. Doerschuk CM, Tasaka S, Wang Q. CD11/CD18-dependent and -independent neutrophil emigration in the lungs: how do neutrophils know which route to take? Am J Respir Cell Mol Biol 23: 133-136, 2000.
11. Emmanuilidis K, Weighardt H, Matevossian E, Heidecke CD, Ulm K, Bartels H, Siewert JR, Holzmann B. Differential regulation of systemic IL-18 and IL-12 release during postoperative sepsis: high serum IL-18 as an early predictive indicator of lethal outcome. Shock 18: 301-305, 2002.
12. Faggioni R, Cattley RC, Guo J, Flores S, Brown H, Qi M, Yin S, Hill D, Scully S, Chen C, Brankow D, Lewis J, Baikalov C, Yamane H, Meng T, Martin F, Hu S, Boone T, Senaldi G. IL-18-binding protein protects against lipopolysaccharide-induced lethality and prevents the development of Fas/Fas ligand-mediated models of liver disease in mice. J Immunol 167: 5913-5920, 2001.
13. Faunce DE, Gregory MS, Kovacs EJ. Effects of acute ethanol exposure on cellular immune responses in a murine model of thermal injury. J Leukoc Biol 62: 733-740, 1997.
14. 2+-mediated neutrophil O responses with thermal injury. Am J Physiol Cell Physiol 283: C1469-C1479, 2002.
15. Gao XP Xu N, Sekosan M, Mehta D, Ma SY, Rahman A, Malik AB. Differential role of CD18 integrins in mediating lung neutrophil sequestration and increased microvascular permeability induced by Escherichia coli in mice. J Immunol 167: 2895-2901, 2001.
16. Gracie JA, Robertson SE, McInnes IB. Interleukin-18. J Leukoc Biol 73: 213-224, 2003.
17. Guo RF, Ward PA. Mediators and regulation of neutrophil accumulation in inflammatory responses in lung: insights from the IgG immune complex model. Free Radic Biol Med 33: 303-310, 2002.
18. Haum A, Perbix W, Hack HJ, Stark GB, Spilker G, Doehn M. Alcohol and drug abuse in burn injuries. Burns 21: 194-199, 1995.
19. Hoek J, Thiele GM, Klassen LW, Mandrekar P, Zakhari S, Cook RT, Ray NB, Happel KI, Kolls JK, Kovacs EJ, Szab G. RSA 2004: combined basic research satellite symposium-mechanisms of alcohol-mediated organ and tissue damage: inflammation and immunity and alcohol and mitochondrial metabolism: at the crossroads of life and death session one: alcohol, cellular and organ damage. Alcohol Clin Exp Res 29: 1735-1743, 2005.
20. Jones JD, Barber B, Engrav L, Heimbach D. Alcohol use and burn injury. J Burn Care Rehabil 12: 148-152, 1991.
21. Jordan JA, Guo RF, Yun EC, Sarma V, Warner RL, Crouch LD, Senaldi G, Ulich TR, Ward PA. Role of IL-18 in acute lung inflammation. J Immunol 167: 7060-7068, 2001.
22. Joshi VD, Kalvakolanu DV, Hebel JR, Hasday JD, Cross AS. Role of caspase 1 in murine antibacterial host defenses and lethal endotoxemia. Infect Immun 70: 6896-6903, 2002.
23. Kashiwamura S, Ueda H, Okamura H. Roles of interleukin-18 in tissue destruction and compensatory reactions. J Immunother 25, Suppl 1: S4-S11, 2002.
24. Lederer JA, Rodrick ML, Mannick JA. The effects of injury on the adaptive immune response. Shock 11: 153-159, 1999.
25. Leung BP, Culshaw S, Gracie JA, Hunter D, Canetti CA, Campbell C, Cunha F, Liew FY, McInnes IB. A role for IL-18 in neutrophil activation. J Immunol 167: 2879-2886, 2001.
26. Li X, Rana SN, Kovacs EJ, Gamelli RL, Chaudry IH, Choudhry MA. Corticosterone suppresses mesenteric lymph node T cells by inhibiting p38/ERK pathway and promotes bacterial translocation after alcohol and burn injury. Am J Physiol Regul Integr Comp Physiol 289: R37-R44, 2005.
27. Li X, Rana SN, Schwacha MG, Chaudry IH, Choudhry MA. A novel role for IL-18 in corticosterone-mediated intestinal damage in a two-hit rodent model of alcohol intoxication and injury. J Leukoc Biol 80: 367-375, 2006.
28. Li X, Schwacha MG, Chaudry IH, Choudhry MA. A role of PP1/PP2A in mesenteric lymph node T cell suppression in a two-hit rodent model of alcohol intoxication and injury. J Leukoc Biol 79: 453-462, 2006.
29. Magnotti LJ, Deitch EA. Burns, bacterial translocation, gut barrier function, and failure. J Burn Care Rehabil 26: 383-391, 2005.
30. Mannick JA, Rodrick ML, Lederer JA. The immunologic response to injury. J Am Coll Surg 193: 237-244, 2001.
31. Maybauer MO, Maybauer DM, Herndon DN. Incidence and outcomes of acute lung injury. N Engl J Med 354: 416-417, 2006.
32. McCall JE, Cahill TJ. Respiratory care of the burn patient. J Burn Care Rehabil 26: 200-206, 2005.
33. McGill V, Kowal-Vern A, Fisher SG, Kahn S, Gamelli RL. The impact of substance use on mortality and morbidity from thermal injury. J Trauma 38: 931-934, 1995.
34. McGwin G Jr, Chapman V, Rousculp M, Robison J, Fine P. The epidemiology of fire-related deaths in Alabama, 1992-1997. J Burn Care Rehabil 21: 75-73, 2000.
35. Messingham KA, Faunce DE, Kovacs EJ. Alcohol, injury, and cellular immunity. Alcohol 28: 137-149, 2002.
36. Messingham KA, Heinrich SA, Schilling EM, Kovacs EJ. Interleukin-4 treatment restores cellular immunity after ethanol exposure and burn injury. Alcohol Clin Exp Res 26: 519-526, 2002.
37. Miller SF, Bessey PQ, Schurr MJ, Browning SM, Jeng JC, Caruso DM, Gomez M, Latenser BA, Lentz CW, Saffle JR, Kagan RJ, Purdue GF, Krichbaum JA. National Burn Repository 2005: A Ten-Year Review. J Burn Care Res 27: 411-436, 2006.
38. Murphy TJ, Paterson HM, Mannick JA, Lederer JA. Injury, sepsis, and the regulation of Toll-like receptor responses. J Leukoc Biol 75: 400-407, 2004.
39. Nakanishi K, Yoshimoto T, Tsutsui H, Okamura H. Interleukin-18 regulates both Th1 and Th2 responses. Annu Rev Immunol 19: 423-474, 2001.
40. Netea MG, Fantuzzi G, Kullberg BJ, Stuyt RJ, Pulido EJ, McIntyre RC Jr, Joosten LA, Van der Meer JW, Dinarello CA. Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia. J Immunol 164: 2644-2649, 2000.
41. Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, Rubinstein M. Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response. Immunity 10: 127-136, 1999.
42. Ogle CK, Kong F, Guo X, Wells DA, Aosasa S, Noel G, Horseman N. The effect of burn injury on suppressors of cytokine signalling. Shock 14: 392-398, 2000.
43. Okamura H, Kashiwamura S, Tsutsui H, Yoshimoto T, Nakanishi K. Regulation of interferon-gamma production by IL-12 and IL-18. Curr Opin Immunol 10: 259-264, 1998.
44. Okamura H, Tsutsi H, Komatsu T, Yutsudo M, Hakura A, Tanimoto T, Torigoe K, Okura T, Nukada Y, Hattori K. Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature 378: 88-91, 1995.
45. Patel PJ, Faunce DE, Gregory MS, Duffner LA, Kovacs EJ. Elevation in pulmonary neutrophils and prolonged production of pulmonary macrophage inflammatory protein-2 after burn injury with prior alcohol exposure. Am J Respir Cell Mol Biol 20: 1229-1237, 1999.
46. Perl M, Chung CS, Lomas-Neira J, Rachel TM, Biffl WL, Cioffi WG, Ayala A. Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis. Am J Pathol 167: 1545-1559, 2005.
47. Polikandriotis JA, Rupnow HL, Elms SC, Clempus RE, Campbell DJ, Sutliff RL, Brown LA, Guidot DM, Hart CM. Chronic ethanol ingestion increases superoxide production and NADPH oxidase expression in the lung. Am J Respir Cell Mol Biol 34: 314-319, 2006.
48. Quinton LJ, Nelson S, Zhang P, Boe DM, Happel KI, Pan W, Bagby GJ. Selective transport of cytokine-induced neutrophil chemoattractant from the lung to the blood facilitates pulmonary neutrophil recruitment. Am J Physiol Lung Cell Mol Physiol 286: L465-L472, 2004.
49. Rana SN, Li X, Chaudry IH, Bland KI, Choudhry MA. Inhibition of IL-18 reduces myeloperoxidase activity and prevents edema in intestine following alcohol and burn injury. J Leukoc Biol 77: 719-728, 2005.
50. 2+ signaling in neutrophils: a cause for concern. News Physiol Sci 15: 130-136, 2000.
51. Siegmund B. Interleukin-1beta converting enzyme (caspase-1) in intestinal inflammation. Biochem Pharmacol 64: 1-8, 2002.
52. Sir O, Fazal N, Choudhry MA, Gamelli RL, Sayeed MM. Neutrophil depletion prevents intestinal mucosal permeability alterations in burn-injured rats. Am J Physiol Regul Integr Comp Physiol 278: R1224-R1231, 2000.
53. Sivakumar PV, Westrich GM, Kanaly S, Garka K, Born TL, Derry JM, Viney JL. Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage. Gut 50: 812-820, 2002.
54. Szabo G, Mandrekar P, Verma B, Isaac A, Catalano D. Acute ethanol consumption synergizes with trauma to increase monocyte tumor necrosis factor alpha production late postinjury. J Clin Immunol 14: 340-352, 1994.
55. Toliver-Kinsky TE, Cui W, Murphey ED, Lin C, Sherwood ER. Enhancement of dendritic cell production by fms-like tyrosine kinase-3 ligand increases the resistance of mice to a burn wound infection. J Immunol 174: 404-410, 2005.
56. Toth B, Alexander M, Daniel T, Chaudry IH, Hubbard WJ, Schwacha MG. The role of gammadelta T cells in the regulation of neutrophil-mediated tissue damage after thermal injury. J Leukoc Biol 76: 545-552, 2004.
57. Turnage RH, Nwariaku F, Murphy J, Schulman C, Wright K, Yin H. Mechanisms of pulmonary microvascular dysfunction during severe burn injury. World J Surg 26: 848-853, 2002.
58. Wang X, Adler KB, Chaudry IH, Ward PA. Better understanding of organ dysfunction requires proteomic involvement. J Proteome Res 5: 1060-1062, 2006.
59. Xu N, Gao XP, Minshall RD, Rahman A, Malik AB. Time-dependent reversal of sepsis-induced PMN uptake and lung vascular injury by expression of CD18 antagonist. Am J Physiol Lung Cell Mol Physiol 282: L796-L802, 2002.
60. Yu HP, Yang S, Hsieh YC, Choudhry MA, Bland KI, Chaudry IH. Maintenance of lung myeloperoxidase activity in proestrus females following trauma-hemorrhage: upregulation of hemeoxygenase-1. Am J Physiol Lung Cell Mol Physiol 291: L400-L406, 2006.
61. Zhang P, Bagby GJ, Kolls JK, Welsh DA, Summer WR, Andresen J, Nelson S. The effects of granulocyte colony-stimulating factor and neutrophil recruitment on the pulmonary chemokine response to intratracheal endotoxin. J Immunol 166: 458-465, 2001.