메뉴 건너뛰기




Volumn 27, Issue 14, 2007, Pages 5067-5078

DNA damage checkpoints inhibit mitotic exit by two different mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

CDC14 PROTEIN; CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE; PHOSPHATASE; POLO LIKE KINASE; UNCLASSIFIED DRUG;

EID: 34447515850     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00095-07     Document Type: Article
Times cited : (35)

References (41)
  • 1
    • 0242413993 scopus 로고    scopus 로고
    • Two distinct pathways for inhibiting pds1 ubiquitination in response to DNA damage
    • Agarwal, R., Z. Tang, H. Yu, and O. Cohen-Fix. 2003. Two distinct pathways for inhibiting pds1 ubiquitination in response to DNA damage. J. Biol. Chem. 278:45027-45033.
    • (2003) J. Biol. Chem , vol.278 , pp. 45027-45033
    • Agarwal, R.1    Tang, Z.2    Yu, H.3    Cohen-Fix, O.4
  • 2
    • 0035906861 scopus 로고    scopus 로고
    • Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast
    • Alexandru, G., F. Uhlmann, K. Mechtler, M. A. Poupart, and K. Nasmyth. 2001. Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast. Cell 105:459-472.
    • (2001) Cell , vol.105 , pp. 459-472
    • Alexandru, G.1    Uhlmann, F.2    Mechtler, K.3    Poupart, M.A.4    Nasmyth, K.5
  • 4
    • 0038788005 scopus 로고    scopus 로고
    • Mitotic exit regulation through distinct domains within the protein kinase Cdc15
    • Bardiu, A. J., M. G. Boselli, and A. Amon. 2003. Mitotic exit regulation through distinct domains within the protein kinase Cdc15. Mol. Cell. Biol. 23:5018-5030.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 5018-5030
    • Bardiu, A.J.1    Boselli, M.G.2    Amon, A.3
  • 5
    • 0034616929 scopus 로고    scopus 로고
    • A mechanism for coupling exit from mitosis to partitioning of the nucleus
    • Bardin, A. J., R. Visintin, and A. Amon. 2000. A mechanism for coupling exit from mitosis to partitioning of the nucleus. Cell 102:21-31.
    • (2000) Cell , vol.102 , pp. 21-31
    • Bardin, A.J.1    Visintin, R.2    Amon, A.3
  • 6
    • 0037312919 scopus 로고    scopus 로고
    • Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase
    • Bashkirov, V. I., E. V. Bashkirova, E. Haghnazari, and W. D. Heyer. 2003. Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase. Mol. Cell. Biol. 23:1441-1452.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 1441-1452
    • Bashkirov, V.I.1    Bashkirova, E.V.2    Haghnazari, E.3    Heyer, W.D.4
  • 7
    • 33847767159 scopus 로고    scopus 로고
    • Mechanism of Dun1 activation by Rad53 phosphorylation in Saccharomyces cerevisiae
    • Chen, S. H., M. B. Smolka, and H. Zhou. 2007. Mechanism of Dun1 activation by Rad53 phosphorylation in Saccharomyces cerevisiae. J. Biol. Chem. 282:986-995.
    • (2007) J. Biol. Chem , vol.282 , pp. 986-995
    • Chen, S.H.1    Smolka, M.B.2    Zhou, H.3
  • 8
    • 0031785411 scopus 로고    scopus 로고
    • Cell cycle regulation of the Saccharomyces cerevisiae Polo-like kinase Cdc5p
    • Cheng, L., L. Hunke, and C. F. Hardy. 1998. Cell cycle regulation of the Saccharomyces cerevisiae Polo-like kinase Cdc5p. Mol. Cell. Biol. 18:7360-7370.
    • (1998) Mol. Cell. Biol , vol.18 , pp. 7360-7370
    • Cheng, L.1    Hunke, L.2    Hardy, C.F.3
  • 9
    • 0032511150 scopus 로고    scopus 로고
    • An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast
    • Ciosk, R., W. Zachariae, C. Michaelis, A. Shevchenko, M. Mann, and K. Nasmyth. 1998. An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast Cell 93:1067-1076.
    • (1998) Cell , vol.93 , pp. 1067-1076
    • Ciosk, R.1    Zachariae, W.2    Michaelis, C.3    Shevchenko, A.4    Mann, M.5    Nasmyth, K.6
  • 10
    • 0033180066 scopus 로고    scopus 로고
    • Pds1p of budding yeast has dual roles: Inhibition of anaphase initiation and regulation of mitotic exit
    • Cohen-Fix, O., and D. Koshland. 1999. Pds1p of budding yeast has dual roles: inhibition of anaphase initiation and regulation of mitotic exit. Genes Dev. 13:1950-1959.
    • (1999) Genes Dev , vol.13 , pp. 1950-1959
    • Cohen-Fix, O.1    Koshland, D.2
  • 11
    • 7544240594 scopus 로고    scopus 로고
    • At the interface between signaling and executing anaphase - Cdc14 and the FEAR network
    • D'Amours, D., and A. Amon. 2004. At the interface between signaling and executing anaphase - Cdc14 and the FEAR network. Genes Dev. 18:2581-2595.
    • (2004) Genes Dev , vol.18 , pp. 2581-2595
    • D'Amours, D.1    Amon, A.2
  • 12
    • 0034597601 scopus 로고    scopus 로고
    • The spindle checkpoint of Saccharomyces cerevisiae responds to separable microtubule-dependent events
    • Daum, J. R., N. Gomez-Ospina, M. Winey, and D. J. Burke. 2000. The spindle checkpoint of Saccharomyces cerevisiae responds to separable microtubule-dependent events. Curr. Biol. 10:1375-1378.
    • (2000) Curr. Biol , vol.10 , pp. 1375-1378
    • Daum, J.R.1    Gomez-Ospina, N.2    Winey, M.3    Burke, D.J.4
  • 14
    • 0035977126 scopus 로고    scopus 로고
    • Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints
    • Hu, F., Y. Wang, D. Liu, Y. Li, J. Qin, and S. J. Elledge. 2001. Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints. Cell 107:655-665.
    • (2001) Cell , vol.107 , pp. 655-665
    • Hu, F.1    Wang, Y.2    Liu, D.3    Li, Y.4    Qin, J.5    Elledge, S.J.6
  • 15
    • 0042470439 scopus 로고    scopus 로고
    • Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling
    • Lee, S. J., M. F. Schwartz, J. K. Duong, and D. F. Stern. 2003. Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling. Mol. Cell. Biol. 23:6300-6314.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 6300-6314
    • Lee, S.J.1    Schwartz, M.F.2    Duong, J.K.3    Stern, D.F.4
  • 17
    • 0030447657 scopus 로고    scopus 로고
    • The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo
    • Lin, J. J., and V. A. Zakian. 1996. The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo. Proc. Natl. Acad. Sci. USA 93:13760-13765.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13760-13765
    • Lin, J.J.1    Zakian, V.A.2
  • 18
    • 0030464317 scopus 로고    scopus 로고
    • Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast
    • Minshull, J., A. Straight, A. D. Rudner, A. F. Dernburg, A. Belmont, and A. W. Murray. 1996. Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast. Curr. Biol. 6:1609-1620.
    • (1996) Curr. Biol , vol.6 , pp. 1609-1620
    • Minshull, J.1    Straight, A.2    Rudner, A.D.3    Dernburg, A.F.4    Belmont, A.5    Murray, A.W.6
  • 19
    • 0033147334 scopus 로고    scopus 로고
    • Regulation of the APC and the exit from mitosis
    • Morgan, D. O. 1999. Regulation of the APC and the exit from mitosis. Nat. Cell Biol. 1:E47-E53.
    • (1999) Nat. Cell Biol , vol.1
    • Morgan, D.O.1
  • 20
    • 0033974957 scopus 로고    scopus 로고
    • CDK inactivation is the only essential function of the APC/C and the mitotic exit network proteins for origin resetting during mitosis
    • Noton, E., and J. F. Diffley. 2000. CDK inactivation is the only essential function of the APC/C and the mitotic exit network proteins for origin resetting during mitosis. Mol. Cell 5:85-95.
    • (2000) Mol. Cell , vol.5 , pp. 85-95
    • Noton, E.1    Diffley, J.F.2
  • 21
    • 0033636539 scopus 로고    scopus 로고
    • The Bub2p spindle checkpoint links nuclear migration with mitotic exit
    • Pereira, G., T. Hofken, J. Grindlay, C. Manson, and E. Schiebel. 2000. The Bub2p spindle checkpoint links nuclear migration with mitotic exit. Mol. Cell 6:1-10.
    • (2000) Mol. Cell , vol.6 , pp. 1-10
    • Pereira, G.1    Hofken, T.2    Grindlay, J.3    Manson, C.4    Schiebel, E.5
  • 22
    • 33646507278 scopus 로고    scopus 로고
    • Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast
    • Queralt, E., C. Lehane, B. Novak, and F. Uhlmann. 2006. Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast. Cell 125:719-732.
    • (2006) Cell , vol.125 , pp. 719-732
    • Queralt, E.1    Lehane, C.2    Novak, B.3    Uhlmann, F.4
  • 23
    • 0033527787 scopus 로고    scopus 로고
    • Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms
    • Sanchez, Y., J. Bachant, H. Wang, F. Hu, D. Liu, M. Tetzlaff, and S. J. Elledge. 1999. Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms. Science 286:1166-1171.
    • (1999) Science , vol.286 , pp. 1166-1171
    • Sanchez, Y.1    Bachant, J.2    Wang, H.3    Hu, F.4    Liu, D.5    Tetzlaff, M.6    Elledge, S.J.7
  • 24
    • 0030593033 scopus 로고    scopus 로고
    • Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
    • Sanchez, Y., B. A. Desany, W. J. Jones, Q. Liu, B. Wang, and S. J. Elledge. 1996. Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science 271:357-360.
    • (1996) Science , vol.271 , pp. 357-360
    • Sanchez, Y.1    Desany, B.A.2    Jones, W.J.3    Liu, Q.4    Wang, B.5    Elledge, S.J.6
  • 25
    • 0344578064 scopus 로고    scopus 로고
    • APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5
    • Shirayama, M., A. Toth, M. Galova, and K. Nasmyth. 1999. APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5. Nature 402:203-207.
    • (1999) Nature , vol.402 , pp. 203-207
    • Shirayama, M.1    Toth, A.2    Galova, M.3    Nasmyth, K.4
  • 26
    • 0033574594 scopus 로고    scopus 로고
    • Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
    • Shou, W., J. H. Seol, A. Shevchenko, C. Baskerville, D. Moazed, Z. W. Chen, J. Jang, H. Charbonneau, and R. J. Deshaies. 1999. Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell 97:233-244.
    • (1999) Cell , vol.97 , pp. 233-244
    • Shou, W.1    Seol, J.H.2    Shevchenko, A.3    Baskerville, C.4    Moazed, D.5    Chen, Z.W.6    Jang, J.7    Charbonneau, H.8    Deshaies, R.J.9
  • 27
    • 0037169353 scopus 로고    scopus 로고
    • Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase
    • Stegmeier, F., R. Visintin, and A. Amon. 2002. Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase. Cell 108:207-220.
    • (2002) Cell , vol.108 , pp. 207-220
    • Stegmeier, F.1    Visintin, R.2    Amon, A.3
  • 28
    • 0037340260 scopus 로고    scopus 로고
    • A non-proteolytic function of separase links the onset of anaphase to mitotic exit
    • Sullivan, M., and F. Uhlmann. 2003. A non-proteolytic function of separase links the onset of anaphase to mitotic exit. Nat. Cell Biol. 5:249-254.
    • (2003) Nat. Cell Biol , vol.5 , pp. 249-254
    • Sullivan, M.1    Uhlmann, F.2
  • 29
    • 33750833693 scopus 로고    scopus 로고
    • Pds1/Esp1-dependent and -independent sister chromatid separation in mutants defective for protein phosphatase 2A
    • Tang, X., and Y. Wang. 2006. Pds1/Esp1-dependent and -independent sister chromatid separation in mutants defective for protein phosphatase 2A. Proc. Natl. Acad. Sci. USA 103:16290-16295.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16290-16295
    • Tang, X.1    Wang, Y.2
  • 30
    • 0033168496 scopus 로고    scopus 로고
    • Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1
    • Uhlmann, F., F. Lottspeich, and K. Nasmyth. 1999. Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1. Nature 400:37-42.
    • (1999) Nature , vol.400 , pp. 37-42
    • Uhlmann, F.1    Lottspeich, F.2    Nasmyth, K.3
  • 31
    • 0032254350 scopus 로고    scopus 로고
    • The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation
    • Visintin, R., K. Craig, E. S. Hwang, S. Prinz, M. Tyers, and A. Amon. 1998. The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation. Mol. Cell 2:709-718.
    • (1998) Mol. Cell , vol.2 , pp. 709-718
    • Visintin, R.1    Craig, K.2    Hwang, E.S.3    Prinz, S.4    Tyers, M.5    Amon, A.6
  • 32
    • 0033614303 scopus 로고    scopus 로고
    • Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus
    • Visintin, R., E. S. Hwang, and A. Amon. 1999. Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus. Nature 398:818-823.
    • (1999) Nature , vol.398 , pp. 818-823
    • Visintin, R.1    Hwang, E.S.2    Amon, A.3
  • 33
    • 0034991258 scopus 로고    scopus 로고
    • Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function
    • Wang, H., D. Liu, Y. Wang, J. Qin, and S. J. Elledge. 2001. Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function. Genes Dev. 15:1361-1372.
    • (2001) Genes Dev , vol.15 , pp. 1361-1372
    • Wang, H.1    Liu, D.2    Wang, Y.3    Qin, J.4    Elledge, S.J.5
  • 34
    • 0031046069 scopus 로고    scopus 로고
    • Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae
    • Wang, Y., and D. J. Burke. 1997. Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae. Mol. Cell. Biol. 17:620-626.
    • (1997) Mol. Cell. Biol , vol.17 , pp. 620-626
    • Wang, Y.1    Burke, D.J.2
  • 35
    • 0034597552 scopus 로고    scopus 로고
    • The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit
    • Wang, Y., F. Hu, and S. J. Elledge. 2000. The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit. Curr. Biol. 10:1379-1382.
    • (2000) Curr. Biol , vol.10 , pp. 1379-1382
    • Wang, Y.1    Hu, F.2    Elledge, S.J.3
  • 36
    • 30044444290 scopus 로고    scopus 로고
    • Phosphatase 2A negatively regulates mitotic exit in Saccharomyces cerevisiae
    • Wang, Y., and T. Y. Ng. 2006. Phosphatase 2A negatively regulates mitotic exit in Saccharomyces cerevisiae. Mol. Biol. Cell 17:80-89.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 80-89
    • Wang, Y.1    Ng, T.Y.2
  • 37
    • 0037423917 scopus 로고    scopus 로고
    • Exit from exit: Resetting the cell cycle through Amn1 inhibition of G protein signaling
    • Wang, Y., T. Shirogane, D. Liu, J. W. Harper, and S. J. Elledge. 2003. Exit from exit: resetting the cell cycle through Amn1 inhibition of G protein signaling. Cell 112:697-709.
    • (2003) Cell , vol.112 , pp. 697-709
    • Wang, Y.1    Shirogane, T.2    Liu, D.3    Harper, J.W.4    Elledge, S.J.5
  • 38
    • 0028353634 scopus 로고
    • Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
    • Weinert, T. A., G. L. Kiser, and L. H. Hartwell. 1994. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev. 8:652-665.
    • (1994) Genes Dev , vol.8 , pp. 652-665
    • Weinert, T.A.1    Kiser, G.L.2    Hartwell, L.H.3
  • 39
    • 31944445315 scopus 로고    scopus 로고
    • The role of Cdc55 in the spindle checkpoint is through regulation of mitotic exit in Saccharomyces cerevisiae
    • Yellman, C. M., and D. J. Burke. 2006. The role of Cdc55 in the spindle checkpoint is through regulation of mitotic exit in Saccharomyces cerevisiae. Mol. Biol. Cell 17:658-666.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 658-666
    • Yellman, C.M.1    Burke, D.J.2
  • 40
    • 0037018852 scopus 로고    scopus 로고
    • Mitotic exit network controls the localization of Cdc14 to the spindle pole body in Saccharomyces cerevisiae
    • Yoshida, S., K. Asakawa, and A. Toh-e. 2002. Mitotic exit network controls the localization of Cdc14 to the spindle pole body in Saccharomyces cerevisiae. Curr. Biol. 12:944-950.
    • (2002) Curr. Biol , vol.12 , pp. 944-950
    • Yoshida, S.1    Asakawa, K.2    Toh-e, A.3
  • 41
    • 0027145127 scopus 로고
    • DUN1 encodes a protein kinase that controls the DNA damage response in yeast
    • Zhou, Z., and S. J. Elledge. 1993. DUN1 encodes a protein kinase that controls the DNA damage response in yeast. Cell 75:1119-1127.
    • (1993) Cell , vol.75 , pp. 1119-1127
    • Zhou, Z.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.