p38 kinase regulates nitric oxide-induced apoptosis of articular chondrocytes by accumulating p53 via NF κB-dependent transcription and stabilization by serine 15 phosphorylation

Journal of Biological Chemistry

Volumn 277, Issue 36, 2002, Pages 33501-33508

  Kim, Song Ja ^a,b,c   Hwang, Sang Gu ^a,b,c   Shin, Deug Y ^a,b,c   Kang, Shin Sung ^a,b,c   Chun, Jang Soo ^a,b,c  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Dankook University College of Medicine   (South Korea)

^c Kyungpook National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS;

AMINO ACIDS; CELL CULTURE; CELLS; NITROGEN OXIDES;

ENZYMES;

CASPASE 3; CYTOCHROME C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SERINE; SYNAPTOPHYSIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL NUCLEUS; CHONDROCYTES; CYTOCHROME C GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; LUCIFERASES; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; NF-KAPPA B; NITRIC OXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PRECIPITIN TESTS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RABBITS; SERINE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0037031848     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M202862200     Document Type: Article

References (56)