Role of Methionine Adenosyltransferase 2A and S-adenosylmethionine in Mitogen-Induced Growth of Human Colon Cancer Cells

Gastroenterology

Volumn 133, Issue 1, 2007, Pages 207-218

  Chen, Hui ^a   Xia, Meng ^a   Lin, Mark ^a   Yang, Heping ^a   Kuhlenkamp, John ^a   Li, Tony ^a   Sodir, Nicole M ^b   Chen, Yong Heng ^a   Josef Lenz, Heinz ^a   Laird, Peter W ^b   Clarke, Steven ^c   Mato, José M ^d   Lu, Shelly C ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d CIC BIOGUNE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

5' METHYLTHIOADENOSINE PHOSPHORYLASE; DRINKING WATER; EPIDERMAL GROWTH FACTOR; LEPTIN; MESSENGER RNA; METHIONINE ADENOSYLTRANSFERASE; METHIONINE ADENOSYLTRANSFERASE 2A; NITROBLUE TETRAZOLIUM; S ADENOSYLMETHIONINE; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER GROWTH; COLON CANCER; COLON POLYP; COLON RESECTION; DISEASE ASSOCIATION; ENZYME MECHANISM; GENE ACTIVITY; HUMAN; HUMAN CELL; NITROBLUE TETRAZOLIUM TEST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TISSUE SECTION; UPREGULATION;

EID: 34447284073     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2007.03.114     Document Type: Article

References (41)

1. Lu S.C., and Mato J.M. Role of methionine adenosyltransferase and SAMe in alcohol-associated liver cancer. Alcohol 35 (2005) 227-234
2. Kotb M., Mudd S.H., Mato J.M., Geller A.M., Kredich N.M., Chou J.Y., and Cantoni G.L. Consensus nomenclature for the mammalian methionine adenosyltransferase genes and gene products. Trends Genet 13 (1997) 51-52
3. Cai J., Sun W.M., Hwang J., Stain S., and Lu S.C. Changes in S-adenosylmethionine synthetase in human liver cancer: molecular characterization and significance. Hepatology 24 (1996) 1090-1097
4. Huang Z., Mao Z., Cai J., and Lu S.C. Changes in methionine adenosyltransferase during liver regeneration in the rat. Am J Physiol 38 (1998) G14-G21
5. Cai J., Mao Z., Hwang J., and Lu S.C. Differential expression of methionine adenosyltransferase genes influences the rate of growth of human hepatocellular carcinoma cells. Cancer Res 58 (1998) 1444-1450
6. Garcia-Trevijano E.R., Latasa M.U., Carretero M.V., Berasain C., Mato J.M., and Avila M.A. S-Adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the differentiated status of the liver. FASEB J 14 (2000) 2511-2518
7. Yang H.P., Huang Z.Z., Zeng Z.H., Chen C.J., Selby R.R., and Lu S.C. Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer. Am J Physiol 280 (2001) G184-G190
8. Ansorena E., García-Trevijano E.R., Martínez-Chantar M.L., Huang Z.Z., Chen L.X., Mato J.M., Iraburu M., Lu S.C., and Avila M.A. S-adenosylmethionine and methylthioadenosine are anti-apoptotic in cultured rat hepatocytes but pro-apoptotic in human hepatoma cells. Hepatology 35 (2002) 274-280
9. S. Hepatology 40 (2004) 221-231
10. Tobeña R., Horikawa S., Calvo V., and Alemany S. Interleukin-2 induces γ-S-adenosyl-L-methionine synthetase gene expression during T-lymphocyte activation. Biochem J 319 (1996) 929-933
11. Ito K., Ikeda S., Kojima N., Miura M., Shimizu-Saito K., Yamaguchi I., Katsuyama I., Sanada K., Iwai T., Senoo H., and Horikawa S. Correlation between the expression of methionine adenosyltransferase and the stages of human colorectal carcinoma. Surg Today 30 (2000) 706-710
12. Reinmuth N., Fan F., Liu W., Parikh A.A., Stoeltzing O., Jung Y.D., Bucana C.D., Radinsky R., Gallick G.E., and Ellis L.M. Impact of insulin-like growth factor receptor-1 function on angiogenesis, growth, and metastasis of colon cancer. Lab Invest 82 (2002) 1377-1389
13. LeRoith D., and Roberts Jr. C.T. The insulin-like growth factor system and cancer. Cancer Lett 195 (2003) 127-137
14. Roberts R.B., Min L., Washington M.K., Olsen S.J., Settle S.H., Coffey R.J., and Threadgill D.W. Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis. Proc Natl Acad Sci U S A 99 (2002) 1521-1526
15. Yokoi J., Thaker P.H., Yazici S., Rebhun R.R., Nam D.H., He J., Kim S.J., Abbruzzese J.L., Hamilton S.R., and Fidler I.J. Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduced growth and metastasis of human colon carcinoma in an orthotopic nude mouse model. Cancer Res 65 (2005) 3716-3725
16. Stattin P., Lukanova A., Biessy C., Söderberg S., Palmqvist R., Kaaks R., Olsson T., and Jellum E. Obesity and colon cancer: does leptin provide a link?. Int J Cancer 109 (2004) 149-152
17. Attoub S., Noe V., Pirola L., Bruyneel E., Chastre E., Mareel M., Wymann M.P., and Gespach C. Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase, Rho- and Rac-dependent signaling pathways. FASEB J 14 (2000) 2329-2338
18. Min/+ mice. Cancer Res 66 (2006) 8430-8438
19. Hardwick J.C.H., Van Den Brink G.R., Offerhaus G.J., Van Deventer S.J.H., and Peppelenbosch M.P. Leptin is a growth factor for colonic epithelial cells. Gastroenterology 121 (2001) 79-90
20. Vandesomeple J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., and Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3 (2002) 34.1-34.11
21. Giulietti A., Overbergh L., Valckx D., Decallonne B., Bouillon R., and Mathieu C. An overview of real-time quantitative PCR: applications to quantify cytokine gene expression. Methods 25 (2001) 386-401
22. Yang H.P., Sadda M.R., Yu V., Zeng Y., Lee T.D., Ou X.P., Chen L.X., and Lu S.C. Induction of human methionine adenosyltransferase 2A expression by tumor necrosis factor alpha: Role of NF-μB and AP-1. J Biol Chem 278 (2003) 50887-50896
23. Lee T.D., Yang H.P., Whang J., and Lu S.C. Cloning and characterization of the human glutathione synthetase 5'-flanking region. Biochem J 390 (2005) 521-528
24. Farrar C., and Clarke S. Altered levels of S-adenosylmethionine and S-adenosylhomocysteine in the brains of L-isoaspartyl (D-aspartyl) O-methyltransferase-deficient mice. J Biol Chem 277 (2002) 27856-27863
25. Brown N.D., and Strickler M.P. Femtomolar ion-pair high-performance liquid chromatographic method for determining Dns-polyamine derivatives of red blood cell extracts utilizing an automated polyamine analyzer. J Chromatogr 245 (1982) 101-108
26. Halim A.B., Legros L., Geller A., and Kotb M. Expression and functional interaction of the catalytic and regulatory subunits of human methionine adenosyltransferase in mammalian cells. J Biol Chem 274 (1999) 29720-29725
27. Clarke S.G. Inhibition of mammalian protein methyltransferases by 5'-methylthioadenosine (MTA): a mechanism of action of dietary SAMe?. Enzymes 24 (2006) 467-493
28. Pascale R.M., Simile M.M., Satta G., Seddaiu M.A., Daino L., Pinna G., Vinci M.A., Gaspa L., and Feo F. Comparative effects of L-methionine, S-adenosyl-L-methionine and 5'-methylthioadenosine on the growth of preneoplastic lesions and DNA methylation in rat liver during the early stages of hepatocarcinogenesis. Anticancer Res 11 (1991) 1617-1624
29. Mato J.M., and Lu S.C. S-adenosylmethionine. In: Coates P.M., Blackman M.R., Levine M., Moss J., and White J.D. (Eds). Encyclopedia of dietary supplements (2005), Marcel Dekker, New York. http://www.dekker.com/sdek/abstract~db=enc~content=a713479736 Available at: http://www.dekker.com/sdek/abstract∼db=enc∼content=a713479736.
30. Martínez-Chantar M.L., Garcia-Trevijano E.R., Latasa M.U., Martin-Duce A., Fortes P., Caballeria J., Avila M.A., and Mato J.M. Methionine adenosyltransferase II β subunit gene expression provides a proliferative advantage in human hepatoma. Gastroenterology 124 (2003) 940-948
31. Martínez-Chantar M.L., Vázquez-Chantada M., Garnacho-Echevarria M., Latasa M.U., Varela-Rey M., Dotor J., Santamaria M., Martínez-Cruz L.A., Parada L.A., Lu S.C., and Mato J.M. S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase. Gastroenterology 131 (2006) 223-232
32. Kim Y.I. Role of folate in colon cancer development and progression. J Nutr 133 (2003) 3731S-3739S
33. Giovannucci E., Rimm E.B., Ascherio A., Stampfer M.J., Colditz G.A., and Willett W.C. Alcohol, low-methionine-low-folate diets, and risk of colon cancer in men. J Natl Cancer Inst 87 (1995) 265-273
34. Laird P.W., Jackson-Grusby L., Fazeli A., Dickinson S.L., Jung W.E., Li E., Weinberg R.A., and Jaenisch R. Suppression of intestinal neoplasia by DNA hypomethylation. Cell 81 (1995) 197-205
35. Latasa M.U., Boukaba A., GarcÌa-Trevijano E.R., Torres L., Rodríguez J., Caballería L., Lu S.C., López-Rodas G., Franco L., Mato J.M., and Avila M.A. Hepatocyte growth factor induces MAT2A expression and histone acetylation in rat hepatocytes: role in liver regeneration. FASEB J 15 (2001) 1248-1250
36. Veal N., Hsieh C.L., Xiong S., Mato J.M., Lu S.C., and Tsukamoto H. Inhibition of lipopolysaccharide-stimulated TNFα promoter activity by S-adenosylmethionine and 5'-methylthioadenosine. Am J Physiol 287 (2004) G352-G362
37. Dante R., Anaud M., and Niveleau A. Effects of 5'deoxy-5'-methylthioadenosine on the metabolism of S-adenosylmethionine. Biochem Biophys Res Commun 114 (1983) 214-221
38. Yang H.P., Huang Z.Z., Wang J.H., and Lu S.C. The role of c-Myb and Sp1 in the up-regulation of methionine adenosyltransferase 2A gene expression in human hepatocellular carcinoma. FASEB J 15 (2001) 1507-1516
39. Tobeña R., Horikawa S., Calvo V., and Alemany S. Interleukin-2 induces γ-S-adenosyl-L-methionine synthetase gene expression during T-lymphocyte activation. Biochem J 319 (1996) 929-933
40. Feinberg A.P., and Tycko B. The history of cancer epigenetics. Nat Rev Cancer 4 (2004) 143-153
41. Martínez-Chantar M.L., Corrales F.J., Martínez-Cruz A., García-Trevijano E.R., Huang Z.Z., Chen L.X., Kanel G., Avila M.A., Mato J.M., and Lu S.C. Spontaenous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A. FASEB J 16 (2002) 1292-1294