Changes in S-adenosylmethionine synthetase in human liver cancer: Molecular characterization and significance

Hepatology

Volumn 24, Issue 5, 1996, Pages 1090-1097

  Cai, Jiaxin ^a   Sun, Wei Min ^a   Hwang, Jung Joo ^a   Stain, Steven C ^a   Lu, Shelly C ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DNA; ETHIONINE; LACTATE DEHYDROGENASE; METHIONINE ADENOSYLTRANSFERASE; METHIONINE DERIVATIVE; RNA; S ADENOSYLMETHIONINE;

ADULT; AGED; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CANCER; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING;

EID: 0029907559     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.1996.v24.pm0008903381     Document Type: Article

References (35)

1. Pajares MA, Corrales F, Duran C, Mato JM, Alvarez L. How is rat S-adenozylmethionine synthetase regulated? FEBS Lett 1992;309:1-4.
2. Sufrin JR, Lombardini JB. Differences in the active-site region of tumor versus normal isozymes of mammalian ATP:L-methionine S-adenosyltransferase. Mol Pharmacol 1982;22:752-759.
3. Porter CW, Sufrin JR, Keith DD. Growth inhibition by methionine analog inhibitors of S-adenosylmethionine biosynthesis in the absence of polyamine depletion. Biochem Biophys Res Commun 1984; 122:350-357.
4. Horikawa S, Ozasa H, Ota K, Tsukada K. Immunohistochemical analysis of rat S-adenosylmethionine synthetase isozymes in developmental liver. FEBS Lett 1993;330:307-311.
5. Horikawa S, Tsukada K. Molecular cloning and developmental expression of a human kidney S-adenosylmethionine synthetase. FEBS Lett 1992; 312:37-41.
6. Horikawa S, Tsukada K. Molecular cloning and nucleotide sequence of cDNA encoding the human liver S-adenosylmethionine synthetase. Biochem International 1991;25:81-90.
7. Sullivan DM, Hoffman J. Fractionation and kinetic properties of rat liver and kidney methionine adenosyltransferase isozymes. Biochemistry 1983; 22:1636-1641.
8. Pajares MA, Duran C, Corrales F, Pliego M, Mato JM. Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione. J Biol Chem 1992;267:17598-17605.
9. Liau MC, Chang CF, Becker FF. Alteration of S-adenosylmethionine synthetases during chemical hepatocarcinogenesis and in resulting carcinomas. Cancer Res 1979;39:2113-2119.
10. Lombardini JB, Sufrin JR. Chemotherapeutic potential of methionine analogue inhibitors of tumor-derived methionine adenosyltransferases. Biochem Pharmacol 1983;32:489-495.
11. Sufrin JR, Lombardini JB, Alks V. Differential kinetic properties of L-2-amino-4-methylthio-cis-but-3-enoic acid, a methionine analog inhibitor of S-adenosylmethionine synthetase. Biochim Biophys Acta 1993;1202:87-91.
12. Liau MC, Chang CF, Belanger L, Grenier A. Correlation of isozyme patterns of S-adenosylmethionine synthetase with fetal stages and pathologic states of the liver. Cancer Res 1979;39:162-169.
13. Liau MC, Lin GW, Hurlbert RB. Partial purification and characterization of tumor and liver S-adenosylmethionine synthetase. Cancer Res 1977;37: 427-435.
14. Lu SC, Huang H. Comparison of sulfur amino acids utilization for GSH synthesis in HepG2 cells and rat hepatocytes. Biochem Pharmacol 1994; 47:859-869.
15. Hirokawa S, Kobayashi Y, Sugiyama T, Terashima H, Wada K, Tsukada K. Expression of non-hepatic-type S-adenosylmethionine synthetase isozyme in rat hepatomas induced by 3′-methyl-4-dimethylaminoazobenzene. FEBS Lett 1993;334:69-71.
16. Alvarez L, Corrales F, Martin-Duce A, Mato JM. Characterization of a full-length cDNA encoding human liver S-adenosylmethionine synthetase: tissue-specific gene expression and mRNA levels in hepatopathies. Biochem J 1993;293:481-486.
17. Moldeus P, Hogberg J, Orrenius S. Isolation and use of liver cells. Methods Enzymol 1978;51:60-70.
18. Ryan CM, Carter EA, Jenkins RL, Steerling LM, Yarmush ML, Malt RA, Tompkins RG. Isolation and long-term culture of human hepatocytes. Surgery 1993;113:48-54.
19. Cabrero C, Duce AM, Ortiz P, Alemany A, Mato JM. Specific loss of the high-molecular weight form of S-adenosyl-L-methionine synthetase in human liver cirrhosis. HEPATOLOGY 1988;8:1530-1534.
20. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-254.
21. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
22. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. Ed 2. New York: Cold Spring Harbor Laboratory Press, 1989: 9.16-9.19.
23. Cai J, Sun W, Lu SC. Hormonal and cell density regulation of hepatic γ-glutamylcysteine synthetase gene expression. Mol Pharmacol 1995;48: 212-218.
24. Tokunaga K, Taniguchi H, Yoda K, Shimizu M, Sakiyama S. Nucleotide sequence of full-length cDNA from mouse cytoskeletal β-actin mRNA. Nucleic Acids Res 1986;14:2829.
25. Kramer DL, Sufrin JR, Porter CW. Relative effects of S-adenosylmethionine depletion on nucleic acid methylation and polyamine biosynthesis. Biochem J 1987;247:259-265.
26. Cabrero C, Puerta J, Alemany S. Purification and comparison of two forms of S-adenosyl-L-methionine synthetase from rat liver. Eur J Biochem 1987; 170:299-304.
27. Finkelstein JD. Methionine metabolism in mammals. J Nutr Biochem 1990;1:228-237.
28. Duce AM, Ortiz P, Cabrero C, Mato JM. S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis. HEPATOLOGY 1988;8:65-68.
29. Reid LM, Jefferson DM. Culturing hepatocytes and other differentiated cells. HEPATOLOGY 1984;4:548-559.
30. Runnegar M, Kong S, Zhong Y, Lu SC. Inhibition of GSH synthesis by cyanobacterial alkaloid Cylindrospermopsin in cultured rat hepatocytes. Biochem Pharmacol 1995;49:219-225.
31. Rawson NE, Ulrich PM, Friedman MI. L-ethionine, an amino acid analogue, stimulates eating in rats. Am J Physiol 1994;267:R612-615.
32. Okada G, Sawai Y, Teraoka H, Tsukada K. Differential effects of dimethylsulfoxide on S-adenosylmethionine synthetase from rat liver and hepatoma. FEBS Lett 1979;106:25-28.
33. Hancock RL. S-adenosylmethionine-synthesizing activity of normal and neoplastic mouse tissue. Cancer Res 1966;26:2425-2430.
34. Tsukada K, Okada G. S-adenosylmethionine synthetase isozyme patterns from rat hepatoma induced by N-2-fluorenlyacetamide. Biochem Biophys Res Commun 1980;94:1078-1082.
35. Horikawa S, Sasuga J, Shimizu K, Ozasa H, Tsukada K. Molecular cloning and nucleotide sequence of cDNA encoding the rat kidney S-adenosylmethionine synthetase. J Biol Chem 1990;265:13683-13686.