Differential expression of methionine adenosyltransferase genes influences the rate of growth of human hepatocellular carcinoma cells

Cancer Research

Volumn 58, Issue 7, 1998, Pages 1444-1450

  Cai, Jiaxin ^a   Mao, Zebin ^a   Hwang, Jung Joo ^a   Lu, Shelly C ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHIONINE ADENOSYLTRANSFERASE;

ARTICLE; CANCER GROWTH; GENE EXPRESSION REGULATION; GROWTH REGULATION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CARCINOMA, HEPATOCELLULAR; CELL DIVISION; DNA, NEOPLASM; GENE EXPRESSION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; METHIONINE ADENOSYLTRANSFERASE; TUMOR CELLS, CULTURED;

EID: 0032054726     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Pajares, M. A., Corrales, F., Duran, C., Mato, J. M., and Alvarez, L. How is rat S-adenosylmethionine synthetase regulated? FEBS Lett., 309: 1-4, 1992.
2. Surfin, J. R., and Lombardini, J. B. Differences in the active-site region of tumor versus normal isozymes of mammalian ATP:L-methionine S-adenosyltransferase. Mol. Pharmacol., 22: 752-759, 1982.
3. Horikawa, S., and Tsukada, K. Molecular cloning and developmental expression of a human kidney S-adenosylmethionine synthetase. FEBS Lett., 312: 37-41, 1992.
4. Horikawa, S., and Tsukada, K. Molecular cloning and nucleotide sequence of cDNA encoding the human liver S-adenosylmethionine synthetase. Biochem. Int., 25: 81-90, 1991.
5. Kotb, M., Mudd, S. H., Mato, J. M., Geller, A. M., Kredich, N. M., Chou, J. Y., and Cantoni, G. L. Consensus nomenclature for the mammalian methionine adenosyltransferase genes and gene products. Trends Genet., 13: 51-52, 1997.
6. Horikawa, S., Ozasa, H., Ota, K., and Tsukada, K. Immunohistochemical analysis of rat S-adenosylmethionine synthetase isozymes in developmental liver. FEBS Lett., 330: 307-311, 1993.
7. Gil, B., Casado, M., Pajares, M., Boscá, L., Mato, J. M., Martín-Sanz, P., and Alvarez, L. Differential expression pattern of methionine adenosyltransferase isoenzymes during rat liver development. Hepatology, 24: 876-881, 1996.
8. Okada, G., Teraoka, H., and Tsukada, K. Multiple species of mammalian S-adenosylmethionine synthetase: partial purification and characterization. Biochemistry, 20: 934-940, 1981.
9. Sullivan, D. M., and Hoffman, J. Fractionation and kinetic properties of rat liver and kidney methionine adenosyltransferase isozymes. Biochemistry, 22: 1636-1641, 1983.
10. Pajares, M. A., Duran, C., Corrales, F., Pliego, M., and Mato, J. M. Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione, J. Biol. Chem., 267: 17598-17605, 1992.
11. Liau, M. C., Chang, C. F., Belanger, L., and Grenier, A. Correlation of isozyme patterns of S-adenosylmethionine synthetase with fetal stages and pathologic states of the liver. Cancer Res., 39: 162-169, 1979.
12. Cabrero, C., Puerta, J., and Alemany, S. Purification and comparison of two forms of S-adenosyl-L-methionine synthetase from rat liver. Eur. J. Biochem., 170: 299-304, 1987.
13. Cai, J., Sun, W. M., Hwang, J. J., Stain, S., and Lu, S. C. Changes in S-adenosylmethionine synthetase in human liver cancer: molecular characterization and significance. Hepatology, 24: 1090-1097, 1996.
14. Finkelstein, J. D. Methionine metabolism in mammals. J. Nutr. Biochem., 1: 228-237, 1990.
15. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72: 248-254, 1976.
16. Chomczynski, P., and Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162: 156-159, 1987.
17. Sánchez-Góngora, E., Pastorino, J. G., Alvarez, L., Pajares, M. A., García, C., Viña, J. R., Mato. J. M., and Farber, J. L. Increased sensitivity to oxidative injury in Chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA. Biochem. J., 319: 767-773, 1996.
18. Gil, B., Pajares, M. A., Mato, J. M., and Alvarez, L. Glucocorticoid regulation of hepatic S-adenosylmethionine synthetase gene expression. Endocrinology, 138: 1251-1258, 1997.
19. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual, Ed. 2, pp. 13.7-13.8 and 16.3-16.4. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
20. Chiang, M. Y., Chan, H., Zounes, M. A., Freier, S. M., Lima, W. F., and Bennett, C. F. Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms. J. Biol. Chem., 206: 18162-18171, 1991.
21. Lu, S. C., Ge, J., Huang, H., Kuhlenkamp, J., and Kaplowitz, N. Thiol-disulfide effects on hepatic GSH transport: studies in cultured rat hepatocytes and perfused livers. J. Clin. Invest., 92: 1188-1197, 1993.
22. 3 on epidermal growth factor-induced DNA synthesis in cultured rat hepatocytes. Gastroenterology, 108: 477-486, 1995.
23. Diala, E. S., Cheah, M. S. C., Rowitch, D., and Huffman, R. M. Extent of DNA methylation in human tumor cells. J. Natl. Cancer Inst., 71: 755-764, 1983.
24. Geller, A. M., Kotb, M. Y. S., Jernigan, H. M., Jr., and Kredich, N. M. Methionine adenosyltransferase and J-adenosylmethionine in the developing rat lens. Exp. Eye Res., 47: 197-204, 1988.
25. Mato, J. M., Alvarez, L., Corrales, F. J., and Pajares, M. A. S-adenosylmethionine and the liver. In: I. M. Arias, J. L. Boyer, N. Fausto, W. B. Jakoby, D. A. Schachter, and D. A. Shafritz (eds.), The Liver: Biology and Pathobiology, Ed. 3, pp. 461-470. New York: Raven Press, Ltd., 1994.
26. Finkelstein, J. D., and Martin, J. J. Methionine metabolism in mammals: adaptation to methionine excess. J. Biol. Chem., 261: 1582-1587, 1986.
27. Cabrero, C., Duce, A. M., Ortiz, P., Alemany, A., and Mato, J. M. Specific loss of the high-molecular weight form of S-adenosyl-L-methionine synthetase in human liver cirrhosis. Hepatology, 8: 1530-1534, 1988.
28. Feo, F., Carcea, R., Pascale, R., Pirisi, L., Daino, L., and Donaera, A. The variations of S-adenosyl-L-methionine content modulate hepatocyte growth during phenobarbital promotion of diethylnitrosamine-induced rat liver carcinogenesis. Toxicol. Pathol., 15: 109-114, 1987.
29. Garcea, R., Pascale, R., Daino, L., Frassetto, S., Cozzolina, P., Ruggiu, M. E., Vannini, M. G., Gaspa, L., and Feo, F. Variations of ornithine decarboxylase activity and S-adenosyl-L-methionine and 5′-methylthioadenosine contents during the development of diethylnitrosamine-induced liver hyperplastic nodules and hepatocellular carcinoma. Carcinogenesis (Lond.), 8: 653-658, 1987.
30. Chiang, P. K., Gordon, R. K., Tal, J., Zeng, G. C. Doctor, B. P., Pardhasaradhi, K., and MaCann, P. P. S-adenosylmethionine and methylation. FASEB J., 10: 471-480, 1996.
31. Russell, D. H., and Lombardini, J. B. Polyamines: enhanced S-adenosyl-L-methionine decarboxylase in rapid growth systems and the relationships between polyamine concentrations and RNA accumulation. Biochim. Biophys. Acta, 240: 273-286, 1971.
32. Bhave, M. R., Wilson, M. J., and Poirier, L. A. c-H-ras and c-K-ras gene hypomethylation in the livers and hepatomas of rats fed methyl-deficient, amino aciddefined diets. Carcinogenesis (Lond.), 9: 343-348, 1988.
33. Wainfan, E., and Poirier, L. A. Methyl groups in carcinogenesis: effects on DNA methylation and gene expression. Cancer Res., 52: 2071s-2077s, 1992.
34. Pascale, R., Simile, M. M., Ruggiu, M. E., Seddaiu, M. A., Satta, G., Sequenza, M. J., Daino, L., Vannini, M. G., Lai, P., and Feo, F. Reversal by 5-azacytidine of the S-adenosyl-L-methionine-induced inhibition of the development of putative preneoplastic foci in rat liver carcinogenesis. Cancer Lett., 56: 259-265, 1991.
35. Simile, M. M., Pascale, R., De Miglio, M. R., Nufris, A., Daino, L., Seddaiu, M. A., Gaspa, L., and Feo, F. Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis. Cancer Lett., 79: 9-16, 1994.