메뉴 건너뛰기




Volumn 133, Issue 11 SUPPL. 1, 2003, Pages

Role of Folate in Colon Cancer Development and Progression

Author keywords

Animal models; Chemoprevention; Colorectal cancer; Folate

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); AMINO ACID; CASEIN; DIMETHYLHYDRAZINE; DNA; FOLIC ACID; TUMOR MARKER;

EID: 0242610825     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/133.11.3731s     Document Type: Conference Paper
Times cited : (316)

References (94)
  • 1
    • 0037164104 scopus 로고    scopus 로고
    • Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis
    • The Homocysteine Studies Collaboration. (2002) Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. J. Am. Med. Assoc. 288: 2015-2022.
    • (2002) J. Am. Med. Assoc. , vol.288 , pp. 2015-2022
  • 2
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
    • Boushey, C. J., Beresford, S. A., Omenn, G. S. & Motulsky, A. G. (1995) A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. J. Am. Med. Assoc. 274: 1049-1057.
    • (1995) J. Am. Med. Assoc. , vol.274 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.2    Omenn, G.S.3    Motulsky, A.G.4
  • 3
    • 0032569645 scopus 로고    scopus 로고
    • Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease
    • Ray, J. G. (1998) Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease. Arch. Intern. Med. 158: 2101-2106.
    • (1998) Arch. Intern. Med. , vol.158 , pp. 2101-2106
    • Ray, J.G.1
  • 4
    • 0025863475 scopus 로고
    • Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study
    • MRC Vitamin Study Research Group. (1991) Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 338: 131-137.
    • (1991) Lancet , vol.338 , pp. 131-137
  • 9
    • 0001716641 scopus 로고    scopus 로고
    • Food standards: Amendment of standards of identity for enriched grain products to require addition of folic acid. Final rule. 21 CFR Parts 136, 137, and 139
    • U.S. Food and Drug Administration. (1996) Food standards: amendment of standards of identity for enriched grain products to require addition of folic acid. Final rule. 21 CFR Parts 136, 137, and 139. Fed. Regist. 61: 8781-8807.
    • (1996) Fed. Regist. , vol.61 , pp. 8781-8807
  • 10
    • 0001117066 scopus 로고    scopus 로고
    • Regulations amending the Food and Drug Regulations (1066)
    • Health Canada. (1997) Regulations amending the Food and Drug Regulations (1066). Canada Gazette Part 1. 131: 3702-3737.
    • (1997) Canada Gazette Part 1 , vol.131 , pp. 3702-3737
  • 11
    • 0036328028 scopus 로고    scopus 로고
    • Folate status: Effects on pathways of colorectal carcinogenesis
    • Choi, S. W. & Mason, J. B. (2002) Folate status: effects on pathways of colorectal carcinogenesis. J. Nutr. 132: 2413S-2418S.
    • (2002) J. Nutr. , vol.132
    • Choi, S.W.1    Mason, J.B.2
  • 12
    • 0033007272 scopus 로고    scopus 로고
    • Folate and carcinogenesis: Evidence, mechanisms, and implications
    • Kim, Y. I. (1999) Folate and carcinogenesis: evidence, mechanisms, and implications. J. Nutr. Biochem 10: 66-88.
    • (1999) J. Nutr. Biochem. , vol.10 , pp. 66-88
    • Kim, Y.I.1
  • 13
    • 0032704132 scopus 로고    scopus 로고
    • Folate and cancer prevention: A new medical application of folate beyond hyperhomocysteinemia and neural tube defects
    • Kim, Y. I. (1999) Folate and cancer prevention: a new medical application of folate beyond hyperhomocysteinemia and neural tube defects. Nutr. Rev. 57: 314-321.
    • (1999) Nutr. Rev. , vol.57 , pp. 314-321
    • Kim, Y.I.1
  • 14
    • 0038549053 scopus 로고    scopus 로고
    • Folic acid supplements and fortification affect the risk for neural tube defects, vascular disease and cancer: Evolving science
    • Bailey, L. B., Rampersaud, G. C. & Kauwell, G. P. (2003) Folic acid supplements and fortification affect the risk for neural tube defects, vascular disease and cancer: evolving science. J. Nutr. 133: 1961S-1968S.
    • (2003) J. Nutr. , vol.133
    • Bailey, L.B.1    Rampersaud, G.C.2    Kauwell, G.P.3
  • 15
    • 0036324027 scopus 로고    scopus 로고
    • Epidemiologic studies of folate and colorectal neoplasia: A review
    • Giovannucci, E. (2002) Epidemiologic studies of folate and colorectal neoplasia: a review. J. Nutr. 132: 2350S-2355S.
    • (2002) J. Nutr. , vol.132
    • Giovannucci, E.1
  • 16
    • 0020009781 scopus 로고
    • The effects of alcohol on folate metabolism
    • Hillman, R. S. & Steinberg, S. E. (1982) The effects of alcohol on folate metabolism. Annu. Rev. Med. 33: 345-354.
    • (1982) Annu. Rev. Med. , vol.33 , pp. 345-354
    • Hillman, R.S.1    Steinberg, S.E.2
  • 21
    • 0033869675 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphisms, folate, and cancer risk: A paradigm of gene-nutrient interactions in carcinogenesis
    • Kim, Y. I. (2000) Methylenetetrahydrofolate reductase polymorphisms, folate, and cancer risk: a paradigm of gene-nutrient interactions in carcinogenesis. Nutr. Rev. 58: 205-209.
    • (2000) Nutr. Rev. , vol.58 , pp. 205-209
    • Kim, Y.I.1
  • 22
    • 0033792616 scopus 로고    scopus 로고
    • Colorectal cancer complicating ulcerative colitis: A review
    • Eaden, J. A. & Mayberry, J. F. (2000) Colorectal cancer complicating ulcerative colitis: a review. Am. J. Gastroenterol. 95: 2710-2719.
    • (2000) Am. J. Gastroenterol. , vol.95 , pp. 2710-2719
    • Eaden, J.A.1    Mayberry, J.F.2
  • 23
    • 0035080617 scopus 로고    scopus 로고
    • The risk of colorectal cancer in ulcerative colitis: A meta-analysis
    • Eaden, J. A., Abrams, K. R. & Mayberry, J. F. (2001) The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 48: 526-535.
    • (2001) Gut , vol.48 , pp. 526-535
    • Eaden, J.A.1    Abrams, K.R.2    Mayberry, J.F.3
  • 24
    • 0024413724 scopus 로고
    • Effect of folate supplementation on the incidence of dysplasia and cancer in chronic ulcerative colitis. A case-control study
    • Lashner, B. A., Heidenreich, P. A., Su, G. L., Kane, S. V. & Hanauer, S. B. (1989) Effect of folate supplementation on the incidence of dysplasia and cancer in chronic ulcerative colitis. A case-control study. Gastroenterology 97: 255-259.
    • (1989) Gastroenterology , vol.97 , pp. 255-259
    • Lashner, B.A.1    Heidenreich, P.A.2    Su, G.L.3    Kane, S.V.4    Hanauer, S.B.5
  • 25
    • 0027173712 scopus 로고
    • Red blood cell folate is associated with the development of dysplasia and cancer in ulcerative colitis
    • Lashner, B. A. (1993) Red blood cell folate is associated with the development of dysplasia and cancer in ulcerative colitis. J. Cancer Res. Clin. Oncol. 119: 549-554.
    • (1993) J. Cancer Res. Clin. Oncol. , vol.119 , pp. 549-554
    • Lashner, B.A.1
  • 26
    • 0031025741 scopus 로고    scopus 로고
    • The effect of folic acid supplementation on the risk for cancer or dysplasia in ulcerative colitis
    • Lashner, B. A., Provencher, K. S., Seidner, D. L., Knesebeck, A. & Brzezinski, A. (1997) The effect of folic acid supplementation on the risk for cancer or dysplasia in ulcerative colitis. Gastroenterology 112: 29-32.
    • (1997) Gastroenterology , vol.112 , pp. 29-32
    • Lashner, B.A.1    Provencher, K.S.2    Seidner, D.L.3    Knesebeck, A.4    Brzezinski, A.5
  • 27
    • 0032586401 scopus 로고    scopus 로고
    • What can randomized controlled trials tell us about nutrition and cancer prevention?
    • Byers, T. (1999) What can randomized controlled trials tell us about nutrition and cancer prevention? CA Cancer J. Clin. 49: 353-361.
    • (1999) CA Cancer J. Clin. , vol.49 , pp. 353-361
    • Byers, T.1
  • 29
    • 0031775688 scopus 로고    scopus 로고
    • Effect of folate supplementation on DNA methylation of rectal mucosa in patients with colonic adenomas: Correlation with nutrient intake
    • Cravo, M. L., Pinto, A. G., Chaves, P., Cruz, J. A., Lage, P., Nobre Leitao, C. & Costa Mira, F. (1998) Effect of folate supplementation on DNA methylation of rectal mucosa in patients with colonic adenomas: correlation with nutrient intake. Clin. Nutr. 17: 45-49.
    • (1998) Clin. Nutr. , vol.17 , pp. 45-49
    • Cravo, M.L.1    Pinto, A.G.2    Chaves, P.3    Cruz, J.A.4    Lage, P.5    Nobre Leitao, C.6    Costa Mira, F.7
  • 30
    • 0028574318 scopus 로고
    • Folate supplementation and adenomatous colonic polyps
    • Paspatis, G. A. & Karamanolis, D. G. (1994) Folate supplementation and adenomatous colonic polyps. Dis. Colon Rectum 37: 1340-1341.
    • (1994) Dis. Colon Rectum , vol.37 , pp. 1340-1341
    • Paspatis, G.A.1    Karamanolis, D.G.2
  • 31
    • 0035133904 scopus 로고    scopus 로고
    • Effects of folate supplementation on two provisional molecular markers of colon cancer: A prospective, randomized trial
    • Kim, Y. I., Baik, H. W., Fawaz, K., Knox, T., Lee, Y. M., Norton, R., Libby, E. & Mason, J. B. (2001) Effects of folate supplementation on two provisional molecular markers of colon cancer: a prospective, randomized trial. Am. J. Gastroenterol. 96: 184-195.
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 184-195
    • Kim, Y.I.1    Baik, H.W.2    Fawaz, K.3    Knox, T.4    Lee, Y.M.5    Norton, R.6    Libby, E.7    Mason, J.B.8
  • 32
    • 0036077320 scopus 로고    scopus 로고
    • Effect of folate supplementation on mucosal cell proliferation in high risk patients for colon cancer
    • Khosraviani, K., Weir, H. P., Hamilton, P., Moorehead, J. & Williamson, K. (2002) Effect of folate supplementation on mucosal cell proliferation in high risk patients for colon cancer. Gut 51: 195-199.
    • (2002) Gut , vol.51 , pp. 195-199
    • Khosraviani, K.1    Weir, H.P.2    Hamilton, P.3    Moorehead, J.4    Williamson, K.5
  • 36
    • 0033913644 scopus 로고    scopus 로고
    • Molecular genetics of hereditary nonpolyposis colorectal cancer
    • discussion 59-61
    • Boland, C. R. (2000) Molecular genetics of hereditary nonpolyposis colorectal cancer. Ann. N Y. Acad. Sci. 910: 50-59; discussion 59-61.
    • (2000) Ann. N. Y. Acad. Sci. , vol.910 , pp. 50-59
    • Boland, C.R.1
  • 39
    • 0033082210 scopus 로고    scopus 로고
    • Evaluation of the usefulness of testing for p53 mutations in colorectal cancer surveillance for ulcerative colitis
    • Lashner, B. A., Shapiro, B. D., Husain, A. & Goldblum, J. R. (1999) Evaluation of the usefulness of testing for p53 mutations in colorectal cancer surveillance for ulcerative colitis. Am. J. Gastroenterol. 94: 456-462.
    • (1999) Am. J. Gastroenterol. , vol.94 , pp. 456-462
    • Lashner, B.A.1    Shapiro, B.D.2    Husain, A.3    Goldblum, J.R.4
  • 41
    • 0036372284 scopus 로고    scopus 로고
    • The promise and peril of surrogate end points in cancer research
    • Schatzkin, A. & Gail, M. (2002) The promise and peril of surrogate end points in cancer research. Nat. Rev. Cancer 2: 19-27.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 19-27
    • Schatzkin, A.1    Gail, M.2
  • 43
    • 0026795472 scopus 로고
    • Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats
    • Cravo, M. L., Mason, J. B., Dayal, Y., Hutchinson, M., Smith, D., Selhub, J. & Rosenberg, I. H. (1992) Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats. Cancer Res. 52: 5002-5006.
    • (1992) Cancer Res. , vol.52 , pp. 5002-5006
    • Cravo, M.L.1    Mason, J.B.2    Dayal, Y.3    Hutchinson, M.4    Smith, D.5    Selhub, J.6    Rosenberg, I.H.7
  • 44
    • 0030452582 scopus 로고    scopus 로고
    • Dietary folate protects against the development of macroscopic colonic neoplasia in a dose responsive manner in rats
    • Kim, Y. I., Salomon, R. N., Graeme-Cook, F., Choi, S. W., Smith, D. E., Dallal, G. E. & Mason, J. B. (1996) Dietary folate protects against the development of macroscopic colonic neoplasia in a dose responsive manner in rats. Gut 39: 732-740.
    • (1996) Gut , vol.39 , pp. 732-740
    • Kim, Y.I.1    Salomon, R.N.2    Graeme-Cook, F.3    Choi, S.W.4    Smith, D.E.5    Dallal, G.E.6    Mason, J.B.7
  • 45
    • 0029003648 scopus 로고
    • Role of aberrant crypt foci in understanding the pathogenesis of colon cancer
    • Bird, R. P. (1995) Role of aberrant crypt foci in understanding the pathogenesis of colon cancer. Cancer Lett. 93: 55-71.
    • (1995) Cancer Lett. , vol.93 , pp. 55-71
    • Bird, R.P.1
  • 46
    • 0001079231 scopus 로고    scopus 로고
    • Potential chemopreventive activity of perillyl alcohol and enhancement of experimental colon carcinogenesis by folic acid and genistein
    • Reddy, B. S., Wang, C. X., Aliaga, C., Rao, C. V., Lubet, R. A., Steele, V. E. & Kelloff, G. J. (1996) Potential chemopreventive activity of perillyl alcohol and enhancement of experimental colon carcinogenesis by folic acid and genistein. Proc. Am. Assoc. Cancer Res. 37: A1849.
    • (1996) Proc. Am. Assoc. Cancer Res. , vol.37
    • Reddy, B.S.1    Wang, C.X.2    Aliaga, C.3    Rao, C.V.4    Lubet, R.A.5    Steele, V.E.6    Kelloff, G.J.7
  • 49
    • 0033695424 scopus 로고    scopus 로고
    • Folate deficiency diminishes the occurrence of aberrant crypt foci in the rat colon but does not alter global DNA methylation status
    • Le Leu, R. K., Young, G. P. & McIntosh, G. H. (2000) Folate deficiency diminishes the occurrence of aberrant crypt foci in the rat colon but does not alter global DNA methylation status. J. Gastroenterol. Hepatol. 15: 1158-1164.
    • (2000) J. Gastroenterol. Hepatol. , vol.15 , pp. 1158-1164
    • Le Leu, R.K.1    Young, G.P.2    McIntosh, G.H.3
  • 50
    • 0034519889 scopus 로고    scopus 로고
    • Folate deficiency reduces the development of colorectal cancer in rats
    • Le Leu, R. K., Young, G. P. & McIntosh, G. H. (2000) Folate deficiency reduces the development of colorectal cancer in rats. Carcinogenesis 21: 2261-2265.
    • (2000) Carcinogenesis , vol.21 , pp. 2261-2265
    • Le Leu, R.K.1    Young, G.P.2    McIntosh, G.H.3
  • 51
    • 0023719696 scopus 로고
    • Folate deficiency in rats fed diets containing free amino acids or intact proteins
    • Walzem, R. L. & Clifford, A. J. (1988) Folate deficiency in rats fed diets containing free amino acids or intact proteins. J. Nutr. 118: 1089-1096.
    • (1988) J. Nutr. , vol.118 , pp. 1089-1096
    • Walzem, R.L.1    Clifford, A.J.2
  • 52
    • 0242630243 scopus 로고    scopus 로고
    • Nutrition and cancer
    • (Bowman, B. & Russell, R., eds.). International Life Sciences Institute Press, Washington, DC
    • Kim, Y. I. (2001) Nutrition and cancer. In: Present knowledge in nutrition, 8th ed. (Bowman, B. & Russell, R., eds.), pp. 573-589. International Life Sciences Institute Press, Washington, DC.
    • (2001) Present Knowledge in Nutrition, 8th Ed. , pp. 573-589
    • Kim, Y.I.1
  • 53
    • 0022371726 scopus 로고
    • Rodent models for carcinoma of the colon
    • Rogers, A. E. & Nauss, K. M. (1985) Rodent models for carcinoma of the colon. Dig. Dis. Sci. 30: 87S-102S.
    • (1985) Dig. Dis. Sci. , vol.30
    • Rogers, A.E.1    Nauss, K.M.2
  • 54
    • 0031894880 scopus 로고    scopus 로고
    • Experimental models of colorectal cancer
    • Banerjee, A. & Quirke, P. (1998) Experimental models of colorectal cancer. Dis. Colon Rectum 41: 490-505.
    • (1998) Dis. Colon Rectum , vol.41 , pp. 490-505
    • Banerjee, A.1    Quirke, P.2
  • 55
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser, A. R., Pitot, H. C. & Dove, W. F. (1990) A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247: 322-324.
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1    Pitot, H.C.2    Dove, W.F.3
  • 58
    • 0002942853 scopus 로고
    • Biochemical role of folate in cellular metabolism
    • (Bailey, L. B., ed.). Marcel Dekker, New York
    • Wagner, C. (1995) Biochemical role of folate in cellular metabolism. In: Folate in health and disease (Bailey, L. B., ed.), pp. 23-42. Marcel Dekker, New York.
    • (1995) Folate in Health and Disease , pp. 23-42
    • Wagner, C.1
  • 59
    • 0031442693 scopus 로고    scopus 로고
    • Folate and antifolate pharmacology
    • Kamen, B. (1997) Folate and antifolate pharmacology. Semin. Oncol. 24: S18-30-S18-39.
    • (1997) Semin. Oncol. , vol.24
    • Kamen, B.1
  • 60
  • 61
    • 0007809550 scopus 로고
    • Inhibitoin of the growth of an amethopterin-refractory tumor by dietary restriction of folic acid
    • Rosen, F. (1962) Inhibitoin of the growth of an amethopterin-refractory tumor by dietary restriction of folic acid. Cancer Res. 22: 495-500.
    • (1962) Cancer Res. , vol.22 , pp. 495-500
    • Rosen, F.1
  • 63
    • 0001347264 scopus 로고
    • Some observations on the effect of folic acid antagonists on acute leukemia and other forms of incurable cancer
    • Farber, S. (1949) Some observations on the effect of folic acid antagonists on acute leukemia and other forms of incurable cancer. Blood 4: 160-167.
    • (1949) Blood , vol.4 , pp. 160-167
    • Farber, S.1
  • 64
    • 0036200864 scopus 로고    scopus 로고
    • Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice
    • Sibani, S., Meinyk, S., Pogribny, I. P., Wang, W., Hiou-Tim, F., Deng, L., Trasler, J., James, S. J. & Rozen, R. (2002) Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice. Carcinogenesis 23: 61-65.
    • (2002) Carcinogenesis , vol.23 , pp. 61-65
    • Sibani, S.1    Meinyk, S.2    Pogribny, I.P.3    Wang, W.4    Hiou-Tim, F.5    Deng, L.6    Trasler, J.7    James, S.J.8    Rozen, R.9
  • 65
    • 0034118587 scopus 로고    scopus 로고
    • Chemopreventive effects of dietary folate on intestinal polyps in Apc+/ -Msh2-/- mice
    • Song, J., Sohn, K. J., Medline, A., Ash, C., Gallinger, S. & Kim, Y. I. (2000) Chemopreventive effects of dietary folate on intestinal polyps in Apc+/ -Msh2-/- mice. Cancer Res. 60: 3191-3199.
    • (2000) Cancer Res , vol.60 , pp. 3191-3199
    • Song, J.1    Sohn, K.J.2    Medline, A.3    Ash, C.4    Gallinger, S.5    Kim, Y.I.6
  • 69
    • 0242506237 scopus 로고    scopus 로고
    • Effects of dietary folate on ulcerative colitis-associated colorectal carcinogenesis in the interleukin-2 and β2-microglobulin deficient mice
    • in press
    • Carrier, J., Medline, A., Sohn, K. J., Choi, M., Martin, R., Hwang, S. W. & Kim, Y. I. (2003) Effects of dietary folate on ulcerative colitis-associated colorectal carcinogenesis in the interleukin-2 and β2-microglobulin deficient mice. Cancer Epidemiol. Biomarkers Prev. (in press).
    • (2003) Cancer Epidemiol. Biomarkers Prev.
    • Carrier, J.1    Medline, A.2    Sohn, K.J.3    Choi, M.4    Martin, R.5    Hwang, S.W.6    Kim, Y.I.7
  • 70
    • 0029156966 scopus 로고
    • Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin-2-deficient colitis
    • Simpson, S. J., Mizoguchi, E., Allen, D., Bhan, A. K. & Terhorst, C. (1995) Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin-2-deficient colitis. Eur. J. Immunol. 25: 2618-2625.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 2618-2625
    • Simpson, S.J.1    Mizoguchi, E.2    Allen, D.3    Bhan, A.K.4    Terhorst, C.5
  • 72
    • 0035884596 scopus 로고    scopus 로고
    • Molecular genetics of ulcerative colitis-associated colon cancer in the interleukin 2- and beta(2)-microglobulin-deficient mouse
    • Sohn, K. J., Shah, S. A., Reid, S., Choi, M., Carrier, J., Comiskey, M., Terhorst, C. & Kim, Y. I. (2001) Molecular genetics of ulcerative colitis-associated colon cancer in the interleukin 2- and beta(2)-microglobulin-deficient mouse. Cancer Res. 61: 6912-6917.
    • (2001) Cancer Res. , vol.61 , pp. 6912-6917
    • Sohn, K.J.1    Shah, S.A.2    Reid, S.3    Choi, M.4    Carrier, J.5    Comiskey, M.6    Terhorst, C.7    Kim, Y.I.8
  • 73
    • 0029848516 scopus 로고    scopus 로고
    • How safe are folic acid supplements?
    • Campbell, N. R. (1996) How safe are folic acid supplements? Arch. Intern. Med. 156: 1638-1644.
    • (1996) Arch. Intern. Med. , vol.156 , pp. 1638-1644
    • Campbell, N.R.1
  • 74
    • 0034721664 scopus 로고    scopus 로고
    • Folate status in women of childbearing age - United States
    • Center for Disease Control and Prevention. (2000) Folate status in women of childbearing age - United States. MMWR 49: 962-965.
    • (2000) MMWR , vol.49 , pp. 962-965
  • 75
    • 0035213315 scopus 로고    scopus 로고
    • Folic acid fortification increases red blood cell folate concentrations in the Framingham study
    • Choumenkovitch, S. F., Jacques, P. F., Nadeau, M. R., Wilson, P. W., Rosenberg, I. H. & Selhub, J. (2001) Folic acid fortification increases red blood cell folate concentrations in the Framingham study. J. Nutr. 131: 3277-3280.
    • (2001) J. Nutr. , vol.131 , pp. 3277-3280
    • Choumenkovitch, S.F.1    Jacques, P.F.2    Nadeau, M.R.3    Wilson, P.W.4    Rosenberg, I.H.5    Selhub, J.6
  • 77
    • 0033551352 scopus 로고    scopus 로고
    • The effect of folic acid fortification on plasma folate and total homocysteine concentrations
    • Jacques, P. F., Selhub, J., Bostom, A. G., Wilson, P. W. & Rosenberg, I. H. (1999) The effect of folic acid fortification on plasma folate and total homocysteine concentrations. N. Engl. J. Med. 340: 1449-1454.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1449-1454
    • Jacques, P.F.1    Selhub, J.2    Bostom, A.G.3    Wilson, P.W.4    Rosenberg, I.H.5
  • 78
    • 0033547038 scopus 로고    scopus 로고
    • Trends in serum folate after food fortification
    • Lawrence, J. M., Petitti, D. B., Watkins, M. & Umekubo, M. A. (1999) Trends in serum folate after food fortification. Lancet 354: 915-916.
    • (1999) Lancet , vol.354 , pp. 915-916
    • Lawrence, J.M.1    Petitti, D.B.2    Watkins, M.3    Umekubo, M.A.4
  • 79
    • 0036172584 scopus 로고    scopus 로고
    • Increased red cell folate concentrations in women of reproductive age after Canadian folic acid food fortification
    • Ray, J. G., Vermeulen, M. J., Boss, S. C. & Cole, D. E. (2002) Increased red cell folate concentrations in women of reproductive age after Canadian folic acid food fortification. Epidemiology 13: 238-240.
    • (2002) Epidemiology , vol.13 , pp. 238-240
    • Ray, J.G.1    Vermeulen, M.J.2    Boss, S.C.3    Cole, D.E.4
  • 80
    • 0035919139 scopus 로고    scopus 로고
    • Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects
    • Honein, M. A., Paulozzi, L. J., Mathews, T. J., Erickson, J. D. & Wong, L. Y. (2001) Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects. J. Am. Med. Assoc. 285: 2981-2986.
    • (2001) J. Am. Med. Assoc. , vol.285 , pp. 2981-2986
    • Honein, M.A.1    Paulozzi, L.J.2    Mathews, T.J.3    Erickson, J.D.4    Wong, L.Y.5
  • 83
    • 0032713838 scopus 로고    scopus 로고
    • Folic acid deficiency and cancer: Mechanisms of DNA instability
    • Duthie, S. J. (1999) Folic acid deficiency and cancer: mechanisms of DNA instability. Br. Med. Bull. 55: 578-592.
    • (1999) Br. Med. Bull. , vol.55 , pp. 578-592
    • Duthie, S.J.1
  • 84
    • 0035906343 scopus 로고    scopus 로고
    • DNA damage from micronutrient deficiencies is likely to be a major cause of cancer
    • Ames, B. N. (2001) DNA damage from micronutrient deficiencies is likely to be a major cause of cancer. Mutat. Res. 475: 7-20.
    • (2001) Mutat. Res. , vol.475 , pp. 7-20
    • Ames, B.N.1
  • 85
    • 0035906327 scopus 로고    scopus 로고
    • The role of folic acid and Vitamin B12 in genomic stability of human cells
    • Fenech, M. (2001) The role of folic acid and Vitamin B12 in genomic stability of human cells. Mutat. Res. 475: 57-67.
    • (2001) Mutat. Res. , vol.475 , pp. 57-67
    • Fenech, M.1
  • 86
    • 0027326933 scopus 로고
    • DNA methylation in folate deficiency: Use of CpG methylase
    • Balaghi, M. & Wagner, C. (1993) DNA methylation in folate deficiency: use of CpG methylase. Biochem. Biophys. Res. Commun. 193: 1184-1190.
    • (1993) Biochem. Biophys. Res. Commun. , vol.193 , pp. 1184-1190
    • Balaghi, M.1    Wagner, C.2
  • 87
    • 0029062378 scopus 로고
    • Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats
    • Kim, Y. J., Christman, J. K., Fleet, J. C., Cravo, M. L., Salomon, R. N., Smith, D., Ordovas, J., Selhub, J. & Mason, J. B. (1995) Moderate folate deficiency does not cause global hypomethylation of hepatic and colonic DNA or c-myc-specific hypomethylation of colonic DNA in rats. Am. J. Clin. Nutr. 61: 1083-1090.
    • (1995) Am. J. Clin. Nutr. , vol.61 , pp. 1083-1090
    • Kim, Y.J.1    Christman, J.K.2    Fleet, J.C.3    Cravo, M.L.4    Salomon, R.N.5    Smith, D.6    Ordovas, J.7    Selhub, J.8    Mason, J.B.9
  • 88
    • 0031022797 scopus 로고    scopus 로고
    • Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene
    • Kim, Y. I., Pogribny, I. P., Basnakian, A. G., Miller, J. W., Selhub, J., James, S. J. & Mason, J. B. (1997) Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene. Am. J. Clin. Nutr. 65: 46-52.
    • (1997) Am. J. Clin. Nutr. , vol.65 , pp. 46-52
    • Kim, Y.I.1    Pogribny, I.P.2    Basnakian, A.G.3    Miller, J.W.4    Selhub, J.5    James, S.J.6    Mason, J.B.7
  • 89
    • 0029815819 scopus 로고    scopus 로고
    • Exon-specific DNA hypomethylation of the p53 gene of rat colon induced by dimethylhydrazine. Modulation by dietary folate
    • Kim, Y. I., Pogribny, I. P., Salomon, R. N., Choi, S. W., Smith, D. E., James, S. J. & Mason, J. B. (1996) Exon-specific DNA hypomethylation of the p53 gene of rat colon induced by dimethylhydrazine. Modulation by dietary folate. Am. J. Pathol. 149: 1129-1137.
    • (1996) Am. J. Pathol. , vol.149 , pp. 1129-1137
    • Kim, Y.I.1    Pogribny, I.P.2    Salomon, R.N.3    Choi, S.W.4    Smith, D.E.5    James, S.J.6    Mason, J.B.7
  • 90
    • 0031816123 scopus 로고    scopus 로고
    • Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women
    • Jacob, R. A., Gretz, D. M., Taylor, P. C., James, S. J., Pogribny, I. P., Miller, B. J., Henning, S. M. & Swendseid, M. E. (1998) Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women. J. Nutr. 128: 1204-1212.
    • (1998) J. Nutr. , vol.128 , pp. 1204-1212
    • Jacob, R.A.1    Gretz, D.M.2    Taylor, P.C.3    James, S.J.4    Pogribny, I.P.5    Miller, B.J.6    Henning, S.M.7    Swendseid, M.E.8
  • 91
    • 0033805888 scopus 로고    scopus 로고
    • Genomic DNA methylation decreases in response to moderate folate depletion in elderly women
    • Rampersaud, G. C., Kauwell, G. P., Hutson, A. D., Cerda, J. J. & Bailey, L. B. (2000) Genomic DNA methylation decreases in response to moderate folate depletion in elderly women. Am. J. Clin. Nutr. 72: 998-1003.
    • (2000) Am. J. Clin. Nutr. , vol.72 , pp. 998-1003
    • Rampersaud, G.C.1    Kauwell, G.P.2    Hutson, A.D.3    Cerda, J.J.4    Bailey, L.B.5
  • 92
    • 0031903189 scopus 로고    scopus 로고
    • Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults
    • Fenech, M., Aitken, C. & Rinaldi, J. (1998) Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults. Carcinogenesis 19: 1163-1171.
    • (1998) Carcinogenesis , vol.19 , pp. 1163-1171
    • Fenech, M.1    Aitken, C.2    Rinaldi, J.3
  • 93
    • 0033933478 scopus 로고    scopus 로고
    • DNA stability and genomic methylation status in colonocytes isolated from methyl-donor-deficient rats
    • Duthie, S. J., Narayanan, S., Brand, G. M. & Grant, G. (2000) DNA stability and genomic methylation status in colonocytes isolated from methyl-donor-deficient rats. Eur. J. Nutr. 39: 106-111.
    • (2000) Eur. J. Nutr. , vol.39 , pp. 106-111
    • Duthie, S.J.1    Narayanan, S.2    Brand, G.M.3    Grant, G.4
  • 94
    • 0037272902 scopus 로고    scopus 로고
    • The effect of dietary folate on genomic and P53-specific DNA methylation in rat colon
    • Sohn, K. J., Stempak, J. M., Reid, S., Shirwadkar, S., Mason, J. B. & Kim, Y. I. (2003) The effect of dietary folate on genomic and P53-specific DNA methylation in rat colon. Carcinogenesis 24: 81-90.
    • (2003) Carcinogenesis , vol.24 , pp. 81-90
    • Sohn, K.J.1    Stempak, J.M.2    Reid, S.3    Shirwadkar, S.4    Mason, J.B.5    Kim, Y.I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.