Synthesis of some new pyridylethylated benzoxa(Thia)zolinones with analgesic activitiy

Turkish Journal of Chemistry

Volumn 28, Issue 1, 2004, Pages 123-132

  Gökhan, Nesrin ^a   Aktay, Göknur ^b   Erdoǧan, Hakki ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

^b INONU UNIVERSITY   (Turkey)

Author keywords

2 Benzothiazolinone; 2 Benzoxazolinone; Acylation; Analgesic activity; Pyridylethyl

Indexed keywords

ACETYLSALICYLIC ACID; ANALGESIC AGENT; BENZOTHIAZOLINE DERIVATIVE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG SYNTHESIS; FLUORINATION; HOT PLATE TEST; MALE; MOUSE; NOCICEPTIVE STIMULATION; NONHUMAN; PAIN; STATISTICAL SIGNIFICANCE;

EID: 18344413997     PISSN: 13000527     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. H. Erdoǧan, M. Debaert and J.C. Cazin, Arzneim.-Forsch./Drug Res. 41, 73-76 (1991).
2. E. Palaska, S. Ünlü, H. Erdoǧan, C. Şafak, B. Gümüşel and R. Demirdamar, Eur. J. Med. Chem. 28, 963-967 (1993).
3. N. Gökhan, H. Erdoǧan, N.T. Durlu and R. Demirdamar, Eur. J. Med. Chem. 31, 625-628 (1996).
4. N. Gökhan, H. Erdoǧan, N.T. Durlu and R. Demirdamar, Archiv der Pharmazie Pharm. and Medicinal Chem. 332, 43-50 (1999).
5. E. Palaska, N. Gökhan, H. Erdoǧan, B.C. Tel and R. Demirdamar, Arzneim.-Forsch./Drug Res. 49, 754-758 (1999).
6. W.J. Close, B.D. Tiffany and M.A. Spielman, J. Am. Chem. Soc. 71, 1265, (1949).
7. C. Flouzat, Y. Besson, A. Mattio, J. Bonnet and G. Guillaumet, J. Med. Chem. 36, 497-503 (1993).
8. D. Lesieur, C. Lespagnol and S. Yous, Eur. Patent No. 395 526 (1990). (Chem. Abstr. 114 164208x, 1991).
9. Fujisawa Pharmaceutical Co. Ltd., Jpn. Kokai Tokkyo Koho JP 5 953 475 [8453475] (1984) (Chem Abstr. 101 90983d, 1984).
10. S.H. Ferreira, B.B. Lorenzotti, M. Devissaguet, D. Lesieur and Y. Tsouderos, Br. J. Pharmacol. 114, 303-308 (1995).
11. T. Takashima, Y. Kadoh, S. Kumada, T. Takashima, Y. Kadoh and S. Kumada, Arzneim.-Forsch./Drug Res. 22, 711-715 (1992).
12. K. Tsurumi, Y. Hiramatsu, M. Nozaki, M. Hayashi and H. Fujimura, Arzneim.-Forsch./Drug Res. 22, 716-724 (1972).
13. G. Pilli, H. Erdoǧan and R. Sunal, Arzneim.-Forsch./Drug Res. 43, 12-15 (1993).
14. A. Temizer, N. Özaltin and H. Erdoǧan, Port. Electroc. Acta 5, 33-41 (1987).
15. O.I. Petrov, A.T. Antonova, V.B. Kalcheva and C.G. Veleva, Dokl. Bulg. Akad. Nauk. 47, 31-34 (1994).
16. H. Uçar, K. Van Derpoorten, P. Depovere, D. Lesieur, M. Isa, B. Masereel, J. Delarge and J. H. Poupaert, Tetrahedron 54, 1763-1772 (1998).
17. S.L. Shapiro, I.M. Rose and L. Freedman, L, J. Am. Chem. Soc. 79, 2811-2814 (1957).
18. R. Koster and M. Anderson, Fed. Proc. 18, 412 (1959).
19. J.H. Rosland, S. Hunskaar, O.J. Broch and K. Hole, Pharmacol. Toxicol. 70, 31-37 (1992).
20. J.P. Bonte, D. Lesieur, C. Lespagnol and J.C. Cazin, Eur. J. Med. Chem.-Chim. Ther. 9, 491-498 (1974).
21. H. Aichaoui, J.H. Poupaert, D. Lesieur and J.P. Hénichart, Tetrahedron 47, 6649-6654 (1991).
22. N. Gökhan, H. Erdoǧan, N.T. Durlu and R. Demirdamar, Il Farmaco 54, 112-115 (1999).
23. P.G. Mairesse, J.C. Boivin, D.J. Thomas, M.C. Bermann, J.P. Bonte and D. Lesieur, Acta Cryst. C40, 1019-1020 (1984).