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Volumn 7, Issue 7, 2007, Pages 853-864

Regulation of adult hippocampal neurogenesis: Relevance to depression

Author keywords

Antidepressant; Desipramine; Fluoxetine; Hippocampus; Mood disorders; Neuronal progenitors; Stem cells; Subgranular zone

Indexed keywords

CLOZAPINE; CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; ENDOCANNABINOID; ESTROGEN; FIBROBLAST GROWTH FACTOR 2; GLUTAMIC ACID; LITHIUM; MONOAMINE OXIDASE INHIBITOR; NEUROPEPTIDE Y; NORADRENALIN; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; SUBSTANCE P; VASCULOTROPIN;

EID: 34447130850     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/14737175.7.7.853     Document Type: Review
Times cited : (40)

References (113)
  • 1
    • 0037187646 scopus 로고    scopus 로고
    • Nestler EJ, Barrot M, DiLeone RJ, Eisch AJ, Gold SJ, Monteggia LM. Neurobiology of depression. Neuron 34, 13-25 (2002). •• Comprehensive review discussing the more recent hypothesis for the pathogenesis of depression.
    • Nestler EJ, Barrot M, DiLeone RJ, Eisch AJ, Gold SJ, Monteggia LM. Neurobiology of depression. Neuron 34, 13-25 (2002). •• Comprehensive review discussing the more recent hypothesis for the pathogenesis of depression.
  • 2
    • 0036272279 scopus 로고    scopus 로고
    • Antidepressants and neuroplasticity
    • D'Sa C, Duman RS. Antidepressants and neuroplasticity. Bipolar Disord. 4, 183-194 (2002).
    • (2002) Bipolar Disord , vol.4 , pp. 183-194
    • D'Sa, C.1    Duman, R.S.2
  • 3
    • 0142042983 scopus 로고    scopus 로고
    • Depressed new neurons - adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression
    • Kempermann G, Kronenberg G. Depressed new neurons - adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression. Biol. Psychiatry 54(5), 499-503 (2003).
    • (2003) Biol. Psychiatry , vol.54 , Issue.5 , pp. 499-503
    • Kempermann, G.1    Kronenberg, G.2
  • 4
    • 0033937168 scopus 로고    scopus 로고
    • Jacobs BL, Praag H, Gage FH. Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol. Psychiatry 5(3), 262-269 (2000). •• This review discusses the neurogenic hypothesis of depression.
    • Jacobs BL, Praag H, Gage FH. Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol. Psychiatry 5(3), 262-269 (2000). •• This review discusses the neurogenic hypothesis of depression.
  • 5
    • 23244458855 scopus 로고    scopus 로고
    • Ming GL, Song H. Adult neurogenesis in the mammalian central nervous system. Annu. Rev. Neuroscience 28, 223-250 (2005). • Excellent review on adult neurogenesis.
    • Ming GL, Song H. Adult neurogenesis in the mammalian central nervous system. Annu. Rev. Neuroscience 28, 223-250 (2005). • Excellent review on adult neurogenesis.
  • 6
    • 15544370150 scopus 로고    scopus 로고
    • Adult neurogenesis: From precursors to network and physiology
    • Abrous DN, Koehl M, Le Moal M. Adult neurogenesis: from precursors to network and physiology. Physiol. Rev. 85(2), 523-569 (2005).
    • (2005) Physiol. Rev , vol.85 , Issue.2 , pp. 523-569
    • Abrous, D.N.1    Koehl, M.2    Le Moal, M.3
  • 8
    • 0035833068 scopus 로고    scopus 로고
    • Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus
    • Cameron HA, McKay RD. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J. Comp. Neurol. 435(4), 406-417 (2001).
    • (2001) J. Comp. Neurol , vol.435 , Issue.4 , pp. 406-417
    • Cameron, H.A.1    McKay, R.D.2
  • 9
    • 33845787007 scopus 로고    scopus 로고
    • GABA sets the tempo for activity-dependent adult neurogenesis
    • Ge S, Pradhan DA, Ming GL, Song H. GABA sets the tempo for activity-dependent adult neurogenesis. Trends Neurosci. 30(1), 1-8 (2007).
    • (2007) Trends Neurosci , vol.30 , Issue.1 , pp. 1-8
    • Ge, S.1    Pradhan, D.A.2    Ming, G.L.3    Song, H.4
  • 10
    • 0030937293 scopus 로고    scopus 로고
    • More hippocampal neurons in adult mice living in an enriched environment
    • Kempermann G, Kuhn HG, Gage FH. More hippocampal neurons in adult mice living in an enriched environment. Nature 386(6624), 493-495 (1997).
    • (1997) Nature , vol.386 , Issue.6624 , pp. 493-495
    • Kempermann, G.1    Kuhn, H.G.2    Gage, F.H.3
  • 11
    • 33845209203 scopus 로고    scopus 로고
    • BrdU immunohistochemistry for studying adult neurogenesis: Paradigms, pitfalls, limitations, and validation
    • Philippe T. BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation. Brain Res. Rev. 53(1), 198-214 (2007).
    • (2007) Brain Res. Rev , vol.53 , Issue.1 , pp. 198-214
    • Philippe, T.1
  • 12
  • 13
    • 0344255828 scopus 로고    scopus 로고
    • Learning and adult neurogenesis: Survival with or without proliferation?
    • Prickaerts J, Koopmans G, Blokland A, Scheepens A. Learning and adult neurogenesis: survival with or without proliferation? Neurobiol. Learn. Mem. 81(1), 1-11 (2004).
    • (2004) Neurobiol. Learn. Mem , vol.81 , Issue.1 , pp. 1-11
    • Prickaerts, J.1    Koopmans, G.2    Blokland, A.3    Scheepens, A.4
  • 14
    • 0034671366 scopus 로고    scopus 로고
    • Malberg JE, Eisch AJ, Nestler EJ, Duman RS. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci. 20(24), 9104-9110 (2000). •• First report demonstrating increased hippocampal neurogenesis in response to chronic treatment with antidepressants.
    • Malberg JE, Eisch AJ, Nestler EJ, Duman RS. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci. 20(24), 9104-9110 (2000). •• First report demonstrating increased hippocampal neurogenesis in response to chronic treatment with antidepressants.
  • 15
    • 33645109592 scopus 로고    scopus 로고
    • Hippocampal neurogenesis: Opposing effects of stress and antidepressant treatment
    • Warner-Schmidt JL, Duman RS. Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment. Hippocampus 16(3), 239-249 (2006).
    • (2006) Hippocampus , vol.16 , Issue.3 , pp. 239-249
    • Warner-Schmidt, J.L.1    Duman, R.S.2
  • 16
    • 11844288311 scopus 로고    scopus 로고
    • Animal models of depressive illness: The importance of chronic drug treatment
    • Mitchell PJ, Redfern PH. Animal models of depressive illness: the importance of chronic drug treatment. Curr. Pharm. Des. 11, 171-203 (2005).
    • (2005) Curr. Pharm. Des , vol.11 , pp. 171-203
    • Mitchell, P.J.1    Redfern, P.H.2
  • 17
    • 0032721988 scopus 로고    scopus 로고
    • Stress and hippocampal neurogenesis
    • Gould E, Tanapat P. Stress and hippocampal neurogenesis. Biol. Psychiatry 46(11), 1472-1479 (1999).
    • (1999) Biol. Psychiatry , vol.46 , Issue.11 , pp. 1472-1479
    • Gould, E.1    Tanapat, P.2
  • 18
    • 27744496919 scopus 로고    scopus 로고
    • Quetiapine reverses the suppression of hippocampal neurogenesis caused by repeated restraint stress
    • Luo C, Xu H, Li XM. Quetiapine reverses the suppression of hippocampal neurogenesis caused by repeated restraint stress. Brain Res. 1063(1), 32-39 (2005).
    • (2005) Brain Res , vol.1063 , Issue.1 , pp. 32-39
    • Luo, C.1    Xu, H.2    Li, X.M.3
  • 19
    • 3343015515 scopus 로고    scopus 로고
    • Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress
    • Dong H, Goico B, Martin M, Csernansky CA, Bertchume A, Csernansky JG. Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress. Neuroscience 127(3), 601-609 (2004).
    • (2004) Neuroscience , vol.127 , Issue.3 , pp. 601-609
    • Dong, H.1    Goico, B.2    Martin, M.3    Csernansky, C.A.4    Bertchume, A.5    Csernansky, J.G.6
  • 20
    • 33747355417 scopus 로고    scopus 로고
    • Social stress-related behavior affects hippocampal cell proliferation in mice
    • Mitra R, Sundlass K, Parker KJ, Schatzberg AF, Lyons DM. Social stress-related behavior affects hippocampal cell proliferation in mice. Physiol. Behav. 89(2), 123-127 (2006).
    • (2006) Physiol. Behav , vol.89 , Issue.2 , pp. 123-127
    • Mitra, R.1    Sundlass, K.2    Parker, K.J.3    Schatzberg, A.F.4    Lyons, D.M.5
  • 21
    • 34447122079 scopus 로고    scopus 로고
    • Sleep deprivation inhibits adult neurogenesis in the hippocampus by elevating glucocorticoids
    • Mirescu C, Peters JD, Noiman L, Gould E. Sleep deprivation inhibits adult neurogenesis in the hippocampus by elevating glucocorticoids. Proc. Natl Acad. Sci. USA 103(50), 19170-19175 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.50 , pp. 19170-19175
    • Mirescu, C.1    Peters, J.D.2    Noiman, L.3    Gould, E.4
  • 22
    • 33747037628 scopus 로고    scopus 로고
    • Hippocampal cytogenesis correlates to escitalopram-mediated recovery in a chronic mild stress rat model of depression
    • Jayatissa MN, Bisgaard C, Tingstrom A, Papp M, Wiborg O. Hippocampal cytogenesis correlates to escitalopram-mediated recovery in a chronic mild stress rat model of depression. Neuropsychopharmacology 31(11), 2395-2404 (2006).
    • (2006) Neuropsychopharmacology , vol.31 , Issue.11 , pp. 2395-2404
    • Jayatissa, M.N.1    Bisgaard, C.2    Tingstrom, A.3    Papp, M.4    Wiborg, O.5
  • 23
    • 33947329033 scopus 로고    scopus 로고
    • Acute psychosocial stress reduces cell survival in adult hippocampal neurogenesis without altering proliferation
    • Thomas RM, Hotsenpiller G, Peterson DA. Acute psychosocial stress reduces cell survival in adult hippocampal neurogenesis without altering proliferation. J. Neurosci. 27(11), 2734-2743 (2007).
    • (2007) J. Neurosci , vol.27 , Issue.11 , pp. 2734-2743
    • Thomas, R.M.1    Hotsenpiller, G.2    Peterson, D.A.3
  • 24
    • 33645105249 scopus 로고    scopus 로고
    • Beauquis J, Roig P, Homo-Delarche F, De Nicola A, Saravia F. Reduced hippocampal neurogenesis and number of hilar neurones in streptozotocin-induced diabetic mice: reversion by antidepressant treatment. Eur. J. Neurosci. 23(6), 1539-1546 (2006).
    • Beauquis J, Roig P, Homo-Delarche F, De Nicola A, Saravia F. Reduced hippocampal neurogenesis and number of hilar neurones in streptozotocin-induced diabetic mice: reversion by antidepressant treatment. Eur. J. Neurosci. 23(6), 1539-1546 (2006).
  • 25
    • 33646357521 scopus 로고    scopus 로고
    • Behavioral control of the stressor modulates stress-induced changes in neurogenesis and fibroblast growth factor-2
    • Bland ST, Schmid MJ, Greenwood BN, Watkins LR, Maier SF. Behavioral control of the stressor modulates stress-induced changes in neurogenesis and fibroblast growth factor-2. Neuroreport 17(6), 593-597 (2006).
    • (2006) Neuroreport , vol.17 , Issue.6 , pp. 593-597
    • Bland, S.T.1    Schmid, M.J.2    Greenwood, B.N.3    Watkins, L.R.4    Maier, S.F.5
  • 26
    • 4444273525 scopus 로고    scopus 로고
    • Restraint stress affects hippocampal cell proliferation differently in rats and mice
    • Bain MJ, Dwyer SM, Rusak B. Restraint stress affects hippocampal cell proliferation differently in rats and mice. Neurosci. Lett. 368(1), 7-10 (2004).
    • (2004) Neurosci. Lett , vol.368 , Issue.1 , pp. 7-10
    • Bain, M.J.1    Dwyer, S.M.2    Rusak, B.3
  • 27
    • 0036366999 scopus 로고    scopus 로고
    • Depression: Reduced number of granule cells in the hippocampus of female, but not male rats due to prenatal restraint stress
    • Schmitz C, Rhodes ME, Bludau M et al. Depression: reduced number of granule cells in the hippocampus of female, but not male rats due to prenatal restraint stress. Mol. Psychiatry 7(7), 810-813 (2002).
    • (2002) Mol. Psychiatry , vol.7 , Issue.7 , pp. 810-813
    • Schmitz, C.1    Rhodes, M.E.2    Bludau, M.3
  • 28
    • 23044477824 scopus 로고    scopus 로고
    • Age-dependent susceptibility of adult hippocampal cell proliferation to chronic psychosocial stress
    • Simon M, Czeh B, Fuchs E. Age-dependent susceptibility of adult hippocampal cell proliferation to chronic psychosocial stress. Brain Res. 1049(2), 244-248 (2005).
    • (2005) Brain Res , vol.1049 , Issue.2 , pp. 244-248
    • Simon, M.1    Czeh, B.2    Fuchs, E.3
  • 29
    • 0242391945 scopus 로고    scopus 로고
    • Reduced cell proliferation in the dentate gyrus is not correlated with the development of learned helplessness
    • Vollmayr B, Simonis C, Weber S, Gass P, Henn F. Reduced cell proliferation in the dentate gyrus is not correlated with the development of learned helplessness. Biol. Psychiatry 54(10), 1035-1040 (2003).
    • (2003) Biol. Psychiatry , vol.54 , Issue.10 , pp. 1035-1040
    • Vollmayr, B.1    Simonis, C.2    Weber, S.3    Gass, P.4    Henn, F.5
  • 30
    • 33745655385 scopus 로고    scopus 로고
    • Cell proliferation is influenced by bulbectomy and normalized by imipramine treatment in a region-specific manner
    • Keilhoff G, Becker A, Grecksch G, Bernstein HG, Wolf G. Cell proliferation is influenced by bulbectomy and normalized by imipramine treatment in a region-specific manner. Neuropsychopharmacology 31(6), 1165-1176 (2006).
    • (2006) Neuropsychopharmacology , vol.31 , Issue.6 , pp. 1165-1176
    • Keilhoff, G.1    Becker, A.2    Grecksch, G.3    Bernstein, H.G.4    Wolf, G.5
  • 31
    • 0242391948 scopus 로고    scopus 로고
    • Prenatal stress diminishes neurogenesis in the dentate gyrus of juvenile rhesus monkeys
    • Coe CL, Kramer M, Czeh B et al. Prenatal stress diminishes neurogenesis in the dentate gyrus of juvenile rhesus monkeys. Biol. Psychiatry 54(10), 1025-1034 (2003).
    • (2003) Biol. Psychiatry , vol.54 , Issue.10 , pp. 1025-1034
    • Coe, C.L.1    Kramer, M.2    Czeh, B.3
  • 32
    • 34250356437 scopus 로고    scopus 로고
    • Stressor-specific regulation of distinct brain-derived neurotrophic factor transcripts and cyclic AMP response element-binding protein expression in the postnatal and adult rat hippocampus
    • Epub ahead of print
    • Nair A, Vadodaria KC, Banerjee SB et al. Stressor-specific regulation of distinct brain-derived neurotrophic factor transcripts and cyclic AMP response element-binding protein expression in the postnatal and adult rat hippocampus Neuropsychopharmacology (2007) (Epub ahead of print).
    • (2007) Neuropsychopharmacology
    • Nair, A.1    Vadodaria, K.C.2    Banerjee, S.B.3
  • 33
    • 3343008569 scopus 로고    scopus 로고
    • Early life experience alters response of adult neurogenesis to stress
    • Mirescu C, Peters JD, Gould E. Early life experience alters response of adult neurogenesis to stress. Nat. Neurosci. 7(8), 841-846 (2004).
    • (2004) Nat. Neurosci , vol.7 , Issue.8 , pp. 841-846
    • Mirescu, C.1    Peters, J.D.2    Gould, E.3
  • 34
    • 0042528720 scopus 로고    scopus 로고
    • Santarelli L, Saxe M, Gross C et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301(5634), 805-809 (2003). •• Excellent first report implicating adult hippocampal neurogenesis in antidepressant-mediated behavioral changes.
    • Santarelli L, Saxe M, Gross C et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301(5634), 805-809 (2003). •• Excellent first report implicating adult hippocampal neurogenesis in antidepressant-mediated behavioral changes.
  • 35
    • 33646377899 scopus 로고    scopus 로고
    • Reif A, Fritzen S, Finger M et al. Neural stem cell proliferation is decreased in schizophrenia, but not in depression. Mol. Psychiatry 11(5), 514-522 (2006). •• First postmortem study addressing hippocampal neurogenesis in humans.
    • Reif A, Fritzen S, Finger M et al. Neural stem cell proliferation is decreased in schizophrenia, but not in depression. Mol. Psychiatry 11(5), 514-522 (2006). •• First postmortem study addressing hippocampal neurogenesis in humans.
  • 36
    • 22144497124 scopus 로고    scopus 로고
    • Spalding KL, Bhardwaj RD, Buchholz BA, Druid H, Frisen J. Retrospective birth dating of cells in humans. Cell 122(1), 133-143 (2005). • Important study that suggests novel approaches to study human adult neurogenesis.
    • Spalding KL, Bhardwaj RD, Buchholz BA, Druid H, Frisen J. Retrospective birth dating of cells in humans. Cell 122(1), 133-143 (2005). • Important study that suggests novel approaches to study human adult neurogenesis.
  • 37
    • 7444255996 scopus 로고    scopus 로고
    • Hippocampal volume and depression: A meta-analysis of MRI studies
    • Videbech P, Ravnkilde B. Hippocampal volume and depression: a meta-analysis of MRI studies. Am. J. Psychiatry 161(11), 1957-1966 (2004).
    • (2004) Am. J. Psychiatry , vol.161 , Issue.11 , pp. 1957-1966
    • Videbech, P.1    Ravnkilde, B.2
  • 38
    • 13244273471 scopus 로고    scopus 로고
    • MR-based in vivo hippocampal volumetrics: 2. Findings in neuropsychiatric disorders
    • Geuze E, Vermetten E, Bremner JD. MR-based in vivo hippocampal volumetrics: 2. Findings in neuropsychiatric disorders. Mol. Psychiatry 10(2), 160-184 (2005).
    • (2005) Mol. Psychiatry , vol.10 , Issue.2 , pp. 160-184
    • Geuze, E.1    Vermetten, E.2    Bremner, J.D.3
  • 39
    • 0035784124 scopus 로고    scopus 로고
    • Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus
    • Muller MB, Lucassen PJ, Yassouridis A, Hoogendijk WJ, Holsboer F, Swaab DF. Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus. Eur. J. Neurosci. 14(10), 1603-1612 (2001).
    • (2001) Eur. J. Neurosci , vol.14 , Issue.10 , pp. 1603-1612
    • Muller, M.B.1    Lucassen, P.J.2    Yassouridis, A.3    Hoogendijk, W.J.4    Holsboer, F.5    Swaab, D.F.6
  • 40
    • 34447120290 scopus 로고    scopus 로고
    • What causes the hippocampal volume decrease in depression? Are neurogenesis, glial changes and apoptosis implicated?
    • Epub ahead of print
    • Czeh B, Lucassen PJ. What causes the hippocampal volume decrease in depression? Are neurogenesis, glial changes and apoptosis implicated? Eur. Arch. Psychiatry Clin. Neurosci. (2007) (Epub ahead of print).
    • (2007) Eur. Arch. Psychiatry Clin. Neurosci
    • Czeh, B.1    Lucassen, P.J.2
  • 41
    • 33749325863 scopus 로고    scopus 로고
    • Frodl T, Schaub A, Banac S et al. Reduced hippocampal correlates with executive dysfunctioning in major depression. J. Psychiatry Neurosci. 31(5), 316-323 (2006). • Important report linking structural damage in the hippocampus to cognitive function in depressed patients.
    • Frodl T, Schaub A, Banac S et al. Reduced hippocampal volume correlates with executive dysfunctioning in major depression. J. Psychiatry Neurosci. 31(5), 316-323 (2006). • Important report linking structural damage in the hippocampus to cognitive function in depressed patients.
  • 42
    • 0033432872 scopus 로고    scopus 로고
    • Starkman MN, Giordani B, Gebarski SS, Berent S, Schork MA, Schteingart DE. Decrease in cortisol reverses human hippocampal atrophy following treatment of Cushing's disease. Biol. Psychiatry 46(12), 1595-1602 (1999).
    • Starkman MN, Giordani B, Gebarski SS, Berent S, Schork MA, Schteingart DE. Decrease in cortisol reverses human hippocampal atrophy following treatment of Cushing's disease. Biol. Psychiatry 46(12), 1595-1602 (1999).
  • 43
    • 33845971468 scopus 로고    scopus 로고
    • Expression of brain derived neurotrophic factor, activity-regulated cytoskeleton protein mRNA, and enhancement of adult hippocampal neurogenesis in rats after sub-chronic and chronic treatment with the triple monoamine re-uptake inhibitor tesofensine
    • Larsen MH, Rosenbrock H, Sams-Dodd F, Mikkelsen JD. Expression of brain derived neurotrophic factor, activity-regulated cytoskeleton protein mRNA, and enhancement of adult hippocampal neurogenesis in rats after sub-chronic and chronic treatment with the triple monoamine re-uptake inhibitor tesofensine. Eur. J. Pharmacol. 555(2-3), 115-121 (2007).
    • (2007) Eur. J. Pharmacol , vol.555 , Issue.2-3 , pp. 115-121
    • Larsen, M.H.1    Rosenbrock, H.2    Sams-Dodd, F.3    Mikkelsen, J.D.4
  • 44
    • 1942502240 scopus 로고    scopus 로고
    • Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression
    • 278-286
    • Alonso R, Griebel G, Pavone G, Stemmelin J, Le Fur G, Soubrie P. Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression. Mol. Psychiatry 9(3), 278-286, 224 (2004).
    • (2004) Mol. Psychiatry , vol.9 , Issue.3 , pp. 224
    • Alonso, R.1    Griebel, G.2    Pavone, G.3    Stemmelin, J.4    Le Fur, G.5    Soubrie, P.6
  • 46
    • 33745728406 scopus 로고    scopus 로고
    • Brief treatment with the glucocorticoid receptor antagonist mifepristone normalises the corticosterone-induced reduction of adult hippocampal neurogenesis
    • Mayer JL, Klumpers L, Maslam S, de Kloet ER, Joels M, Lucassen PJ. Brief treatment with the glucocorticoid receptor antagonist mifepristone normalises the corticosterone-induced reduction of adult hippocampal neurogenesis. J. Neuroendocrinol. 18(8), 629-631 (2006).
    • (2006) J. Neuroendocrinol , vol.18 , Issue.8 , pp. 629-631
    • Mayer, J.L.1    Klumpers, L.2    Maslam, S.3    de Kloet, E.R.4    Joels, M.5    Lucassen, P.J.6
  • 47
    • 22344433956 scopus 로고    scopus 로고
    • The antidepressant effect of running is associated with increased hippocampal cell proliferation
    • Bjornebekk A, Mathe AA, Brene S. The antidepressant effect of running is associated with increased hippocampal cell proliferation. Int. J. Neuropsychopharmacol. 8(3), 357-368 (2005).
    • (2005) Int. J. Neuropsychopharmacol , vol.8 , Issue.3 , pp. 357-368
    • Bjornebekk, A.1    Mathe, A.A.2    Brene, S.3
  • 49
    • 33744487636 scopus 로고    scopus 로고
    • Fluoxetine targets early progenitor cells in the adult brain
    • Encinas JM, Vaahtokari A, Enikolopov G. Fluoxetine targets early progenitor cells in the adult brain. Proc. Natl Acad. Sci. USA 103(21), 8233-8238 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.21 , pp. 8233-8238
    • Encinas, J.M.1    Vaahtokari, A.2    Enikolopov, G.3
  • 50
    • 0141669079 scopus 로고    scopus 로고
    • Cell proliferation in adult hippocampus is decreased by inescapable stress: Reversal by fluoxetine treatment
    • Malberg JE, Duman RS. Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharmacology 28(9), 1562-1571 (2003).
    • (2003) Neuropsychopharmacology , vol.28 , Issue.9 , pp. 1562-1571
    • Malberg, J.E.1    Duman, R.S.2
  • 51
    • 33746047443 scopus 로고    scopus 로고
    • Fluoxetine rescues deficient neurogenesis in hippocampus of the Ts65Dn mouse model for Down syndrome
    • Clark S, Schwalbe J, Stasko MR, Yarowsky PJ, Costa AC. Fluoxetine rescues deficient neurogenesis in hippocampus of the Ts65Dn mouse model for Down syndrome. Exp. Neurol. 200(1), 256-261 (2006).
    • (2006) Exp. Neurol , vol.200 , Issue.1 , pp. 256-261
    • Clark, S.1    Schwalbe, J.2    Stasko, M.R.3    Yarowsky, P.J.4    Costa, A.C.5
  • 52
    • 27644524469 scopus 로고    scopus 로고
    • Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine
    • Grote HE, Bull ND, Howard ML et al. Cognitive disorders and neurogenesis deficits in Huntington's disease mice are rescued by fluoxetine. Eur. J. Neurosci. 22(8), 2081-2088 (2005).
    • (2005) Eur. J. Neurosci , vol.22 , Issue.8 , pp. 2081-2088
    • Grote, H.E.1    Bull, N.D.2    Howard, M.L.3
  • 53
    • 0036891428 scopus 로고    scopus 로고
    • Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation: Effects on stress hormone levels and adult hippocampal neurogenesis
    • Czeh B, Welt T, Fischer AK et al. Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation: effects on stress hormone levels and adult hippocampal neurogenesis. Biol. Psychiatry 52(11), 1057-1065 (2002).
    • (2002) Biol. Psychiatry , vol.52 , Issue.11 , pp. 1057-1065
    • Czeh, B.1    Welt, T.2    Fischer, A.K.3
  • 54
    • 33745684603 scopus 로고    scopus 로고
    • Meshi D, Drew MR, Saxe M et al. Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment. Nat. Neurosci. 9(6), 729-731 (2006). •• Important study dissociating increases in hippocampal neurogenesis following enriched environment exposure from specific accompanying behavioral changes.
    • Meshi D, Drew MR, Saxe M et al. Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment. Nat. Neurosci. 9(6), 729-731 (2006). •• Important study dissociating increases in hippocampal neurogenesis following enriched environment exposure from specific accompanying behavioral changes.
  • 55
    • 33846629921 scopus 로고    scopus 로고
    • Becker S, Wojtowicz JM. A model of hippocampal neurogenesis in memory and mood disorders. Trends Cogn. Sci. 11(2), 70-76 (2007). •• Interesting review that suggests a model for the effects of hippocampal neurogenesis on mood-related behavior.
    • Becker S, Wojtowicz JM. A model of hippocampal neurogenesis in memory and mood disorders. Trends Cogn. Sci. 11(2), 70-76 (2007). •• Interesting review that suggests a model for the effects of hippocampal neurogenesis on mood-related behavior.
  • 56
    • 33847108115 scopus 로고    scopus 로고
    • Neurogenesis decreases during brain maturation from adolescence to adulthood
    • He J, Crews FT. Neurogenesis decreases during brain maturation from adolescence to adulthood. Pharmacol. Biochem. Behav. 86(2), 327-333 (2007).
    • (2007) Pharmacol. Biochem. Behav , vol.86 , Issue.2 , pp. 327-333
    • He, J.1    Crews, F.T.2
  • 57
    • 0142103727 scopus 로고    scopus 로고
    • Vermetten E, Vythilingam M, Southwick SM, Charney DS, Bremner JD. Long-term treatment with paroxetine increases verbal declarative memory and hippocampal in posttraumatic stress disorder. Biol. Psychiatry 54(7), 693-702 (2003). • First clinical report suggesting a role for antidepressants in reversing depression-related structural changes.
    • Vermetten E, Vythilingam M, Southwick SM, Charney DS, Bremner JD. Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder. Biol. Psychiatry 54(7), 693-702 (2003). • First clinical report suggesting a role for antidepressants in reversing depression-related structural changes.
  • 58
    • 3042656636 scopus 로고    scopus 로고
    • Hippocampal volume, memory, and cortisol status in major depressive disorder: Effects of treatment
    • Vythilingam M, Vermetten E, Anderson GM et al. Hippocampal volume, memory, and cortisol status in major depressive disorder: effects of treatment. Biol. Psychiatry 56(2), 101-112 (2004).
    • (2004) Biol. Psychiatry , vol.56 , Issue.2 , pp. 101-112
    • Vythilingam, M.1    Vermetten, E.2    Anderson, G.M.3
  • 60
    • 0031950413 scopus 로고    scopus 로고
    • Regulation of neurogenesis by growth factors and neurotransmitters
    • Cameron HA, Hazel TG, McKay RDG. Regulation of neurogenesis by growth factors and neurotransmitters. J. Neurobiol. 36, 287-306 (1998).
    • (1998) J. Neurobiol , vol.36 , pp. 287-306
    • Cameron, H.A.1    Hazel, T.G.2    McKay, R.D.G.3
  • 61
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model of stress related mood disorders
    • Duman RS, Monteggia LM. A neurotrophic model of stress related mood disorders. Biol. Psychiatry 59(12), 1116-1127 (2006).
    • (2006) Biol. Psychiatry , vol.59 , Issue.12 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 62
    • 0033980604 scopus 로고    scopus 로고
    • Serotonin may stimulate granule cell proliferation in the adult hippocampus, as observed in rats grafted with foetal raphe neurons
    • Brezun JM, Daszuta A. Serotonin may stimulate granule cell proliferation in the adult hippocampus, as observed in rats grafted with foetal raphe neurons. Eur. J. Neurosci. 12(1), 391-396 (2000).
    • (2000) Eur. J. Neurosci , vol.12 , Issue.1 , pp. 391-396
    • Brezun, J.M.1    Daszuta, A.2
  • 63
    • 0036833778 scopus 로고    scopus 로고
    • Depletion of norepinephrine decreases the proliferation, but does not influence the survival and differentiation, of granule cell progenitors in the adult rat hippocampus
    • Kulkarni VA, Jha S, Vaidya VA. Depletion of norepinephrine decreases the proliferation, but does not influence the survival and differentiation, of granule cell progenitors in the adult rat hippocampus. Eur. J. Neurosci. 16(10), 2008-2012 (2002).
    • (2002) Eur. J. Neurosci , vol.16 , Issue.10 , pp. 2008-2012
    • Kulkarni, V.A.1    Jha, S.2    Vaidya, V.A.3
  • 65
    • 18144384796 scopus 로고    scopus 로고
    • Neuropeptide Y stimulates neuronal precursor proliferation in the post-natal and adult dentate gyrus
    • Howell OW, Doyle K, Goodman JH et al. Neuropeptide Y stimulates neuronal precursor proliferation in the post-natal and adult dentate gyrus. J. Neurochem. 93(3), 560-570 (2005).
    • (2005) J. Neurochem , vol.93 , Issue.3 , pp. 560-570
    • Howell, O.W.1    Doyle, K.2    Goodman, J.H.3
  • 66
    • 0242456101 scopus 로고    scopus 로고
    • Increased neurogenesis and brain-derived neurotrophic factor in neurokinin-1 receptor gene knockout mice
    • Morceunde S, Gadd CA, Peters M et al. Increased neurogenesis and brain-derived neurotrophic factor in neurokinin-1 receptor gene knockout mice. Eur. J. Neurosci. 18, 1828-1836 (2003).
    • (2003) Eur. J. Neurosci , vol.18 , pp. 1828-1836
    • Morceunde, S.1    Gadd, C.A.2    Peters, M.3
  • 67
    • 26444557412 scopus 로고    scopus 로고
    • The endocannabinoid system drives neural progenitor proliferation
    • Aguado T, Monory K, Palazuelos J et al. The endocannabinoid system drives neural progenitor proliferation. FASEB J. 19(12), 1704-1706 (2005).
    • (2005) FASEB J , vol.19 , Issue.12 , pp. 1704-1706
    • Aguado, T.1    Monory, K.2    Palazuelos, J.3
  • 68
    • 1642331289 scopus 로고    scopus 로고
    • Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone
    • Banasr M, Hery M, Printemps R, Daszuta A. Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone. Neuropsychopharmacology 29(3), 450-460 (2004).
    • (2004) Neuropsychopharmacology , vol.29 , Issue.3 , pp. 450-460
    • Banasr, M.1    Hery, M.2    Printemps, R.3    Daszuta, A.4
  • 69
    • 33745648114 scopus 로고    scopus 로고
    • The α2-adrenoceptor antagonist dexefaroxan enhances hippocampal neurogenesis by increasing the survival and differentiation of new granule cells
    • Rizk P, Salazar J, Raisman-Vozari R et al. The α2-adrenoceptor antagonist dexefaroxan enhances hippocampal neurogenesis by increasing the survival and differentiation of new granule cells. Neuropsychopharmacology 31, 1146-1157 (2006).
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1146-1157
    • Rizk, P.1    Salazar, J.2    Raisman-Vozari, R.3
  • 70
    • 33744466279 scopus 로고    scopus 로고
    • Glutamate as a modulator of embryonic and adult neurogenesis
    • Schlett K. Glutamate as a modulator of embryonic and adult neurogenesis. Curr. Top. Med. Chem. 6(10), 949-960 (2006).
    • (2006) Curr. Top. Med. Chem , vol.6 , Issue.10 , pp. 949-960
    • Schlett, K.1
  • 71
    • 14744283125 scopus 로고    scopus 로고
    • GABA and glutamate systems as therapeutic targets in depression and mood disorders
    • Kendell SF, Krystal JH, Sanacora G. GABA and glutamate systems as therapeutic targets in depression and mood disorders. Expert Opin. Ther. Targets 9(1), 153-168 (2005).
    • (2005) Expert Opin. Ther. Targets , vol.9 , Issue.1 , pp. 153-168
    • Kendell, S.F.1    Krystal, J.H.2    Sanacora, G.3
  • 72
    • 33744957683 scopus 로고    scopus 로고
    • An mGluR2/3 antagonist, MGS0039, exerts antidepressant and anxiolytic effects in behavioral models in rats
    • Yoshimizu T, Shimazaki T, Ito A, Chaki S. An mGluR2/3 antagonist, MGS0039, exerts antidepressant and anxiolytic effects in behavioral models in rats. Psychopharmacology (Berl.) 186(4), 587-593 (2006).
    • (2006) Psychopharmacology (Berl.) , vol.186 , Issue.4 , pp. 587-593
    • Yoshimizu, T.1    Shimazaki, T.2    Ito, A.3    Chaki, S.4
  • 73
    • 0842288995 scopus 로고    scopus 로고
    • Increased cell proliferation in the adult mouse hippocampus following chronic administration of group II metabotropic glutamate receptor antagonist, MGS0039
    • Yoshimizu T, Chaki S. Increased cell proliferation in the adult mouse hippocampus following chronic administration of group II metabotropic glutamate receptor antagonist, MGS0039. Biochem. Biophys. Res. Commun. 315(2), 493-496 (2004).
    • (2004) Biochem. Biophys. Res. Commun , vol.315 , Issue.2 , pp. 493-496
    • Yoshimizu, T.1    Chaki, S.2
  • 74
    • 0037692850 scopus 로고    scopus 로고
    • Chronic AMPA receptor potentiator (LY451646) treatment increases cell proliferation in adult rat hippocampus
    • Bai F, Bergeron M, Nelson DL. Chronic AMPA receptor potentiator (LY451646) treatment increases cell proliferation in adult rat hippocampus. Neuropharmacology 44, 1013-1021 (2003).
    • (2003) Neuropharmacology , vol.44 , pp. 1013-1021
    • Bai, F.1    Bergeron, M.2    Nelson, D.L.3
  • 75
    • 12144290112 scopus 로고    scopus 로고
    • Electroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathways
    • Altar CA, Laeng P, Jurata LW et al. Electroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathways. J. Neurosci. 24(11), 2667-2677 (2004).
    • (2004) J. Neurosci , vol.24 , Issue.11 , pp. 2667-2677
    • Altar, C.A.1    Laeng, P.2    Jurata, L.W.3
  • 76
    • 0442307920 scopus 로고    scopus 로고
    • Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo
    • Farmer J, Zhao X, van Praag H, Wodtke K, Gage FH, Christie BR. Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience 124(1), 71-79 (2004).
    • (2004) Neuroscience , vol.124 , Issue.1 , pp. 71-79
    • Farmer, J.1    Zhao, X.2    van Praag, H.3    Wodtke, K.4    Gage, F.H.5    Christie, B.R.6
  • 77
    • 0042662920 scopus 로고    scopus 로고
    • Enhancement of neurogenesis by running wheel exercises is suppressed in mice lacking NMDA receptor ε1 subunit
    • Kitamura T, Mishina M, Sugiyama H. Enhancement of neurogenesis by running wheel exercises is suppressed in mice lacking NMDA receptor ε1 subunit. Neurosci. Res. (47), 55-63 (2003).
    • (2003) Neurosci. Res , vol.47 , pp. 55-63
    • Kitamura, T.1    Mishina, M.2    Sugiyama, H.3
  • 78
    • 34147178089 scopus 로고    scopus 로고
    • GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states
    • Earnheart JC, Schweizer C, Crestani F et al. GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states. J. Neurosci. 27(14), 3845-3854 (2007).
    • (2007) J. Neurosci , vol.27 , Issue.14 , pp. 3845-3854
    • Earnheart, J.C.1    Schweizer, C.2    Crestani, F.3
  • 79
    • 15044344103 scopus 로고    scopus 로고
    • Neuropeptide expression in rats exposed to chronic mild stresses
    • Sergeyev V, Fetissov S, Mathe AA et al. Neuropeptide expression in rats exposed to chronic mild stresses. Psychopharmacology (Berl.) 178(2-3), 115-124 (2005).
    • (2005) Psychopharmacology (Berl.) , vol.178 , Issue.2-3 , pp. 115-124
    • Sergeyev, V.1    Fetissov, S.2    Mathe, A.A.3
  • 80
    • 0034059631 scopus 로고    scopus 로고
    • Involvement of hippocampal neuropeptide Y in mediating the chronic actions of lithium, electroconvulsive stimulation and citalopram
    • Husum H, Mikkelsen JD, Hogg S, Mathe AA, Mork A. Involvement of hippocampal neuropeptide Y in mediating the chronic actions of lithium, electroconvulsive stimulation and citalopram. Neuropharmcology 39(8), 1463-1473 (2000).
    • (2000) Neuropharmcology , vol.39 , Issue.8 , pp. 1463-1473
    • Husum, H.1    Mikkelsen, J.D.2    Hogg, S.3    Mathe, A.A.4    Mork, A.5
  • 81
    • 34247548709 scopus 로고    scopus 로고
    • Infusion of neuropeptide Y into CA3 region of hippocampus produces antidepressant-like effect via Y1 receptor
    • Ishida H, Shirayama Y, Iwata M et al. Infusion of neuropeptide Y into CA3 region of hippocampus produces antidepressant-like effect via Y1 receptor. Hippocampus 17(4), 271-280 (2007).
    • (2007) Hippocampus , vol.17 , Issue.4 , pp. 271-280
    • Ishida, H.1    Shirayama, Y.2    Iwata, M.3
  • 82
    • 31444441701 scopus 로고    scopus 로고
    • Berton O, Nestler EJ. New approaches to antidepressant drug discovery: beyond monoamines. Nat. Rev. Neurosci. 7(2), 137-151 (2006). •• Excellent review that comprehensively discusses novel targets for antidepressant drug development.
    • Berton O, Nestler EJ. New approaches to antidepressant drug discovery: beyond monoamines. Nat. Rev. Neurosci. 7(2), 137-151 (2006). •• Excellent review that comprehensively discusses novel targets for antidepressant drug development.
  • 83
    • 27644433182 scopus 로고    scopus 로고
    • Jiang W, Zhang Y, Xiao L et al. Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects. J. Clin. Invest. 115(11), 3104-3116 (2005). • Important study implicating endogenous cannabinoids in depression-related structural and behavioral changes.
    • Jiang W, Zhang Y, Xiao L et al. Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects. J. Clin. Invest. 115(11), 3104-3116 (2005). • Important study implicating endogenous cannabinoids in depression-related structural and behavioral changes.
  • 84
    • 33750060283 scopus 로고    scopus 로고
    • Endocannabinoids modulate stress-induced suppression of hippocampal cell proliferation and activation of defensive behaviours
    • Hill MN, Kambo JS, Sun JC, Gorzalka BB, Galea LA. Endocannabinoids modulate stress-induced suppression of hippocampal cell proliferation and activation of defensive behaviours. Eur. J. Neurosci. 24(7), 1845-1849 (2006).
    • (2006) Eur. J. Neurosci , vol.24 , Issue.7 , pp. 1845-1849
    • Hill, M.N.1    Kambo, J.S.2    Sun, J.C.3    Gorzalka, B.B.4    Galea, L.A.5
  • 85
    • 33748427188 scopus 로고    scopus 로고
    • Acute exposure to predator odor elicits a robust increase in corticosterone and a decrease in activity without altering proliferation in the adult hippocampus
    • Thomas RM, Urban JH, Peterson DA. Acute exposure to predator odor elicits a robust increase in corticosterone and a decrease in activity without altering proliferation in the adult hippocampus. Exp. Neurol. 201(2), 308-315 (2006).
    • (2006) Exp. Neurol , vol.201 , Issue.2 , pp. 308-315
    • Thomas, R.M.1    Urban, J.H.2    Peterson, D.A.3
  • 86
    • 0012255780 scopus 로고    scopus 로고
    • Hippocampal remodeling and damage by corticosteroids: Implications for mood disorders
    • Brown ES, Rush AJ, McEwen BS. Hippocampal remodeling and damage by corticosteroids: implications for mood disorders. Neuropsychopharmacology 21(4), 474-484 (1999).
    • (1999) Neuropsychopharmacology , vol.21 , Issue.4 , pp. 474-484
    • Brown, E.S.1    Rush, A.J.2    McEwen, B.S.3
  • 87
    • 9644281636 scopus 로고    scopus 로고
    • The corticoid environment: A determining factor for neural progenitors survival in the adult hippocampus
    • Wong EY, Herbert J. The corticoid environment: a determining factor for neural progenitors survival in the adult hippocampus. Eur. J. Neurosci. 20, 2491-2498 (2004).
    • (2004) Eur. J. Neurosci , vol.20 , pp. 2491-2498
    • Wong, E.Y.1    Herbert, J.2
  • 88
    • 33644823580 scopus 로고    scopus 로고
    • Stimulation of neurogenesis in the hippocampus of the adult rat by fluoxetine requires rhythmic change in corticosterone
    • Huang GJ, Herbert J. Stimulation of neurogenesis in the hippocampus of the adult rat by fluoxetine requires rhythmic change in corticosterone. Biol. Psychiatry 59(7), 619-624 (2006).
    • (2006) Biol. Psychiatry , vol.59 , Issue.7 , pp. 619-624
    • Huang, G.J.1    Herbert, J.2
  • 89
    • 33745676334 scopus 로고    scopus 로고
    • A review and update of mechanisms of estrogen in the hippocampus and amygdala for anxiety and depression behavior
    • Walf AA, Frye CA. A review and update of mechanisms of estrogen in the hippocampus and amygdala for anxiety and depression behavior. Neuropsychopharmacology 31(6), 1097-1111 (2006).
    • (2006) Neuropsychopharmacology , vol.31 , Issue.6 , pp. 1097-1111
    • Walf, A.A.1    Frye, C.A.2
  • 90
    • 33645099949 scopus 로고    scopus 로고
    • Gonadal hormone modulation of hippocampal neurogenesis in the adult
    • Galea LA, Spritzer MD, Barker JM, Pawluski JL. Gonadal hormone modulation of hippocampal neurogenesis in the adult. Hippocampus 16(3), 225-232 (2006).
    • (2006) Hippocampus , vol.16 , Issue.3 , pp. 225-232
    • Galea, L.A.1    Spritzer, M.D.2    Barker, J.M.3    Pawluski, J.L.4
  • 91
    • 0035783450 scopus 로고    scopus 로고
    • Serotonin mediates oestrogen stimulation of cell proliferation in the adult dentate gyrus
    • Banasr M, Hery M, Brezun JM, Daszuta A. Serotonin mediates oestrogen stimulation of cell proliferation in the adult dentate gyrus. Eur. J. Neurosci. 14(9), 1417-1424 (2001).
    • (2001) Eur. J. Neurosci , vol.14 , Issue.9 , pp. 1417-1424
    • Banasr, M.1    Hery, M.2    Brezun, J.M.3    Daszuta, A.4
  • 92
    • 0031734790 scopus 로고    scopus 로고
    • The thyroid axis and depression
    • Jackson IM. The thyroid axis and depression. Thyroid 8(10), 951-956 (1998).
    • (1998) Thyroid , vol.8 , Issue.10 , pp. 951-956
    • Jackson, I.M.1
  • 94
    • 33645527843 scopus 로고    scopus 로고
    • Modulation of adult hippocampal neurogenesis by thyroid hormones: Implications in depressive-like behavior
    • Montero-Pedrazuela A, Venero C, Lavado-Autric R et al. Modulation of adult hippocampal neurogenesis by thyroid hormones: implications in depressive-like behavior. Mol. Psychiatry 11(4), 361-371 (2006).
    • (2006) Mol. Psychiatry , vol.11 , Issue.4 , pp. 361-371
    • Montero-Pedrazuela, A.1    Venero, C.2    Lavado-Autric, R.3
  • 95
    • 13944257674 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus
    • Sairanen M, Lucas G, Ernfors P, Castren M, Castren E. Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus. J. Neurosci. 25(5), 1089-1094 (2005).
    • (2005) J. Neurosci , vol.25 , Issue.5 , pp. 1089-1094
    • Sairanen, M.1    Lucas, G.2    Ernfors, P.3    Castren, M.4    Castren, E.5
  • 96
    • 34248388548 scopus 로고    scopus 로고
    • VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants
    • •• Important study strengthening the hypothesis that trophic factors may be key targets for antidepressant action
    • Warner-Schmidt JL, Duman RS. VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants. Proc. Natl Acad. Sci. USA 104(11), 4647-4652 (2007). •• Important study strengthening the hypothesis that trophic factors may be key targets for antidepressant action.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.11 , pp. 4647-4652
    • Warner-Schmidt, J.L.1    Duman, R.S.2
  • 97
    • 34447134271 scopus 로고    scopus 로고
    • Increasing the levels of insulin-like growth factor-I by an IGF binding protein inhibitor produces anxiolytic and antidepressant-like effects
    • Epub ahead of print
    • Malberg JE, Platt B, Rizzo SJ et al. Increasing the levels of insulin-like growth factor-I by an IGF binding protein inhibitor produces anxiolytic and antidepressant-like effects. Neuropsychopharmacology (2007) (Epub ahead of print).
    • (2007) Neuropsychopharmacology
    • Malberg, J.E.1    Platt, B.2    Rizzo, S.J.3
  • 98
    • 0036460609 scopus 로고    scopus 로고
    • Hippocampal granule neuron production and population size are regulated by levels of bFGF
    • Cheng Y, Black IB, DiCicco-Bloom E. Hippocampal granule neuron production and population size are regulated by levels of bFGF. Eur. J. Neurosci. 15(1), 3-12 (2002).
    • (2002) Eur. J. Neurosci , vol.15 , Issue.1 , pp. 3-12
    • Cheng, Y.1    Black, I.B.2    DiCicco-Bloom, E.3
  • 99
    • 0036239580 scopus 로고    scopus 로고
    • Antidepressant treatments induce the expression of basic fibroblast growth factor in cortical and hippocampal neurons
    • Mallei A, Shi B, Mocchetti I. Antidepressant treatments induce the expression of basic fibroblast growth factor in cortical and hippocampal neurons. Mol. Pharmacol. 61(5), 1017-1024 (2002).
    • (2002) Mol. Pharmacol , vol.61 , Issue.5 , pp. 1017-1024
    • Mallei, A.1    Shi, B.2    Mocchetti, I.3
  • 100
    • 0028815653 scopus 로고
    • Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
    • Nibuya M, Morinobu S, Duman RS. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J. Neurosci. 15(11), 7539-7547 (1995).
    • (1995) J. Neurosci , vol.15 , Issue.11 , pp. 7539-7547
    • Nibuya, M.1    Morinobu, S.2    Duman, R.S.3
  • 101
    • 33750054969 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment
    • Rossi C, Angelucci A, Costantin L et al. Brain-derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment. Eur. J. Neurosci. 24(7), 1850-1856 (2006).
    • (2006) Eur. J. Neurosci , vol.24 , Issue.7 , pp. 1850-1856
    • Rossi, C.1    Angelucci, A.2    Costantin, L.3
  • 102
    • 0142092502 scopus 로고    scopus 로고
    • Hippocampal brain-derived neurotrophic factor but not neurotrophin-3 increases more in mice selected for increased voluntary wheel running
    • Johnson RA, Rhodes JS, Jeffrey SL, Garland T Jr, Mitchell GS. Hippocampal brain-derived neurotrophic factor but not neurotrophin-3 increases more in mice selected for increased voluntary wheel running. Neuroscience 121(1), 1-7 (2003).
    • (2003) Neuroscience , vol.121 , Issue.1 , pp. 1-7
    • Johnson, R.A.1    Rhodes, J.S.2    Jeffrey, S.L.3    Garland Jr, T.4    Mitchell, G.S.5
  • 103
    • 14944358464 scopus 로고    scopus 로고
    • Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects
    • Hoshaw BA, Malberg JE, Lucki I. Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects. Brain Res. 1037(1-2), 204-208 (2005).
    • (2005) Brain Res , vol.1037 , Issue.1-2 , pp. 204-208
    • Hoshaw, B.A.1    Malberg, J.E.2    Lucki, I.3
  • 104
    • 17144409702 scopus 로고    scopus 로고
    • Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk-1 protein expression
    • Heine VM, Zareno J, Maslam S, Joels M, Lucassen PJ. Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk-1 protein expression. Eur. J. Neurosci. 21(5), 1304-1314 (2005).
    • (2005) Eur. J. Neurosci , vol.21 , Issue.5 , pp. 1304-1314
    • Heine, V.M.1    Zareno, J.2    Maslam, S.3    Joels, M.4    Lucassen, P.J.5
  • 105
    • 0346751060 scopus 로고    scopus 로고
    • VEGF is necessary for exercise-induced adult hippocampal neurogenesis
    • Fabel K, Fabel K, Tam B et al. VEGF is necessary for exercise-induced adult hippocampal neurogenesis. Eur. J. Neurosci. 18(10), 2803-2812 (2003).
    • (2003) Eur. J. Neurosci , vol.18 , Issue.10 , pp. 2803-2812
    • Fabel, K.1    Fabel, K.2    Tam, B.3
  • 106
    • 10744230965 scopus 로고    scopus 로고
    • Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches
    • Machold R, Hayashi S, Rutlin M. Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron 39(6), 937-950 (2003).
    • (2003) Neuron , vol.39 , Issue.6 , pp. 937-950
    • Machold, R.1    Hayashi, S.2    Rutlin, M.3
  • 107
    • 26944445027 scopus 로고    scopus 로고
    • Recruitment of the Sonic hedgehog signalling cascade in electroconvulsive seizure-mediated regulation of adult rat hippocampal neurogenesis
    • Banerjee SB, Rajendran R, Dias BG, Ladiwala U, Tole S, Vaidya VA. Recruitment of the Sonic hedgehog signalling cascade in electroconvulsive seizure-mediated regulation of adult rat hippocampal neurogenesis. Eur. J. Neurosci. 22(7), 1570-1580 (2005).
    • (2005) Eur. J. Neurosci , vol.22 , Issue.7 , pp. 1570-1580
    • Banerjee, S.B.1    Rajendran, R.2    Dias, B.G.3    Ladiwala, U.4    Tole, S.5    Vaidya, V.A.6
  • 108
    • 33745222513 scopus 로고    scopus 로고
    • The role of CREB in depression and antidepressant treatment
    • Blendy JA. The role of CREB in depression and antidepressant treatment. Biol. Psychiatry 59(12), 1144-1150 (2006).
    • (2006) Biol. Psychiatry , vol.59 , Issue.12 , pp. 1144-1150
    • Blendy, J.A.1
  • 109
    • 0029992189 scopus 로고    scopus 로고
    • Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus
    • Nibuya M, Nestler EJ, Duman RS. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. J. Neurosci. 16(7), 2365-2372 (1996).
    • (1996) J. Neurosci , vol.16 , Issue.7 , pp. 2365-2372
    • Nibuya, M.1    Nestler, E.J.2    Duman, R.S.3
  • 110
    • 0035338399 scopus 로고    scopus 로고
    • Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect
    • Chen AC, Shirayama Y, Shin KH, Neve RL, Duman RS. Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect. Biol. Psychiatry 49(9), 753-762 (2001).
    • (2001) Biol. Psychiatry , vol.49 , Issue.9 , pp. 753-762
    • Chen, A.C.1    Shirayama, Y.2    Shin, K.H.3    Neve, R.L.4    Duman, R.S.5
  • 111
    • 0036581252 scopus 로고    scopus 로고
    • Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein
    • Nakagawa S, Kim JE, Lee R et al. Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein. J. Neurosci. 22(9), 3673-3682 (2002).
    • (2002) J. Neurosci , vol.22 , Issue.9 , pp. 3673-3682
    • Nakagawa, S.1    Kim, J.E.2    Lee, R.3
  • 112
    • 1642414041 scopus 로고    scopus 로고
    • ATF2, a member of the CREB/ATF family of transcription factors, in chronic stress and consequent to antidepressant treatment: Animal models and human post-mortem brains
    • Laifenfeld D, Karry R, Grauer E, Klein E, Ben-Shachar D. ATF2, a member of the CREB/ATF family of transcription factors, in chronic stress and consequent to antidepressant treatment: animal models and human post-mortem brains. Neuropsychopharmacology 29(3), 589-597 (2004).
    • (2004) Neuropsychopharmacology , vol.29 , Issue.3 , pp. 589-597
    • Laifenfeld, D.1    Karry, R.2    Grauer, E.3    Klein, E.4    Ben-Shachar, D.5
  • 113
    • 0032701291 scopus 로고    scopus 로고
    • Behavioural trait of reactivity to novelty is related to hippocampal neurogenesis
    • Lemaire V, Aurousseau C, Le Moal M, Abrous DN. Behavioural trait of reactivity to novelty is related to hippocampal neurogenesis. Eur. J. Neurosci. (11), 4006-4014 (1999).
    • (1999) Eur. J. Neurosci , vol.11 , pp. 4006-4014
    • Lemaire, V.1    Aurousseau, C.2    Le Moal, M.3    Abrous, D.N.4


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