Depression: Reduced number of granule cells in the hippocampus of female, but not male, rats due to prenatal restraint stress

Molecular Psychiatry

Volumn 7, Issue 7, 2002, Pages 810-813

  Schmitz, C ^a   Rhodes, M E ^b   Bludau, M ^a   Kaplan, S ^c   Ong, P ^a   Ueffing, I ^a   Vehoff, J ^a   Korr, H ^a   Frye, C A ^b  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

Cell loss; Depression; Hippocampus; Prenatal; Stress

Indexed keywords

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL FRACTIONATION; CELL LOSS; CELL VOLUME; CONTROLLED STUDY; DEPRESSION; DISEASE COURSE; DISEASE PREDISPOSITION; FEMALE; GRANULE CELL; HIPPOCAMPUS; IMMOBILIZATION STRESS; MALE; MATING; NONHUMAN; PREGNANCY; PRENATAL PERIOD; PRIORITY JOURNAL; PROGENY; PYRAMIDAL NERVE CELL; RAT;

ANIMALS; CELL COUNT; DEPRESSION; FEMALE; HIPPOCAMPUS; MALE; PREGNANCY; RATS; RATS, LONG-EVANS; RESTRAINT, PHYSICAL; SEX CHARACTERISTICS; STRESS;

EID: 0036366999     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4001118     Document Type: Article

References (16)

1. Changes in progesterone metabolites in the hippocampus can modulate open field and forced swim test behavior of proestrous rats
2. Adult brain neurogenesis and psychiatry: A novel theory of depression
3. Depression, antidepressants, and the shrinking hippocampus
4. The cellular neurobiology of depression
5. Prenatal teratogens and the development of adult mental illness
6. High corticosterone levels in prenatally stressed rats predict persistent paradoxical sleep alterations
7. Cross-national epidemiology of depression and gender
8. Prenatal stress reduces the effectiveness of the neurosteroid 3 alpha, 5 alpha-THP to block kainic-acid-induced seizures
9. Neuron loss in the mouse hippocampus following prenatal injection of tritiated thymidine or saline
10. Neurogenesis in adult mammal: Some progress and problems
11. Alterations induced by gestational stress in brain morphology and hehaviour of the offspring
12. Preserved neuron number in the hippocampus of aged rats with spatial learning deficits
13. Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the 'hippocampus
14. Adrenal hormones suppress cell division in the adult rat dentate gyrus
15. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by anti-depressant treatment with tianeptine
16. Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach