TAK1 downregulation reduces IL-1β induced expression of MMP13, MMP1 and TNF-alpha

Biomedicine and Pharmacotherapy

Volumn 60, Issue 2, 2006, Pages 55-61

  Klatt, Andreas R ^a   Klinger, Gabriele ^a   Neumüller, Olga ^b   Eidenmüller, Bernd ^b   Wagner, Ingrid ^b   Achenbach, Tatjana ^b   Aigner, Thomas ^c   Bartnik, Eckart ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Osteoarthritis; RNAi; TAK1

Indexed keywords

COLLAGENASE 3; COMPLEMENTARY DNA; ENZYME INHIBITOR; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; SMALL INTERFERING RNA; TAK 1 INHIBITOR; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARTILAGE CELL; CATABOLISM; CELL METABOLISM; CELL STIMULATION; CHONDROSARCOMA; DOWN REGULATION; DRUG ACTIVITY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME RELEASE; GENE EXPRESSION; GROWTH PLATE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION;

ANIMALS; CARTILAGE, ARTICULAR; DOWN-REGULATION; GENE EXPRESSION PROFILING; GROWTH PLATE; HUMANS; INTERLEUKIN-1; MAP KINASE KINASE KINASES; MATRIX METALLOPROTEINASES; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOARTHRITIS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33644880523     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2005.08.007     Document Type: Article

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