Amyloid-β-peptide reduces the expression level of mitochondrial cytochrome oxidase subunits

Neurochemical Research

Volumn 32, Issue 9, 2007, Pages 1483-1488

  Hong, Won Kyung ^a   Han, Eun Hae ^a   Kim, Dae Ghon ^b   Ahn, Jung Yup ^a   Park, Jeong Soon ^c   Han, Bok Ghee ^a  

^a Korea Centers for Disease Control and Prevention   (South Korea)

^b Chonbuk National University Medical School   (South Korea)

^c Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Alzheimer's disease (AD); Amyloid beta (A ); Cytochrome oxidase (COX); Human mitochondrial transcription factor 1 (TFAM); Reactive oxygen species (ROS)

Indexed keywords

AMYLOID BETA PROTEIN; CYTOCHROME C OXIDASE; MESSENGER RNA; PROTEIN SUBUNIT; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR;

ALZHEIMER DISEASE; ARTICLE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOSE RESPONSE; GENE EXPRESSION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NEUROTOXICITY; PRIORITY JOURNAL; TUMOR CELL LINE;

AMYLOID BETA-PROTEIN; ELECTRON TRANSPORT COMPLEX IV; GENE EXPRESSION; HUMANS; MITOCHONDRIA; NEUROBLASTOMA; PEPTIDE FRAGMENTS; PROTEIN SUBUNITS; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 34347376745     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-007-9336-7     Document Type: Article

References (24)

1. Selkoe DJ (2001) Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 81(2):741-766
2. Yankner BA, Dawes LR, Fisher S, Villa-Komaroff L, Oster-Granite ML, Neve RL (1989) Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease. Science 245(4916):417-420
3. Maccioni RB, Lavados M, Maccioni CB, Mendoza-Naranjo A (2004) Biological markers of Alzheimer's disease and mild cognitive impairment. Curr Alzheimer Res 1(4):307-314
4. Cardoso SM, Proenca MT, Santos S, Santana I, Oliveira CR (2004a) Cytochrome c oxidase is decreased in Alzheimer's disease platelets. Neurobiol Aging 25(1):105-110
5. Canevari L, Clark JB, Bates TE (1999) Beta-amyloid fragment 25-35 selectively decreases complex IV activity in isolated mitochondria. FEBS Lett 457(1):131-134
6. Song JH, Park JS, Choi JY, Lee YH, Han BK (2000) Mitochondrial dysfunction and oxidative stress in cytotoxicity induced by amyloid peptide. Kor J Gerontol 10(1):35-41
7. Keil U, Bonert A, Marques CA, Scherping I, Weyermann J, Strosznajder JB, Muller-Spahn F, Haass C, Czech C, Pradier L, Muller WE, Eckert A (2004) Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis. J Biol Chem 279(48):50310-50320
8. Mark RJ, Keller JN, Kruman I, Mattson MP (1997) Basic FGF attenuates amyloid beta-peptide-induced oxidative stress, mitochondrial dysfunction, and impairment of Na+/K+-ATPase activity in hippocampal neurons. Brain Res 756(1-2):205-214
9. Abramov AY, Canevari L, Duchen MR (2004) Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. J Neurosci 24(2):565-575
10. Eckert A, Keil U, Marques CA, Bonert A, Frey C, Schussel K, Muller WE (2003) Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease. Biochem Pharmacol 66(8):1627-1634
11. Cecchi C, Fiorillo C, Sorbi S, Latorraca S, Nacmias B, Bagnoli S, Nassi P, Liguri G (2002) Oxidative stress and reduced antioxidant defenses in peripheral cells from familial Alzheimer's patients. Free Radic Biol Med 33(10):1372-1379
12. Cardoso SM, Santana I, Swerdlow RH, Oliveira CR (2004b) Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity. J Neurochem 89(6):1417-1426
13. Anandatheerthavarada HK, Biswas G, Robin MA, Avadhani NG (2003) Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells. J Cell Biol 161(1):41-54
14. Gibson GE, Sheu KF, Blass JP (1998) Abnormalities of mitochondrial enzymes in Alzheimer disease. J Neural Transm 105(8-9):855-870
15. Bennett MC, Diamond DM, Stryker SL, Parks JK, Parker WD Jr (1992) Cytochrome oxidase inhibition: a novel animal model of Alzheimer's disease. J Geriatr Psychiatry Neurol 5(2):93-101
16. Sorbi S, Bird ED, Blass JP (1983) Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain. Ann Neurol 13(1):72-78
17. Atamna H, Frey WH 2nd (2004) A role for heme in Alzheimer's disease: heme binds amyloid beta and has altered metabolism. Proc Natl Acad Sci USA 101(30):11153-11158
18. Parks JK, Smith TS, Trimmer PA, Bennett JP Jr, Parker WD Jr (2001) Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro. J Neurochem 76(4):1050-1056
19. Combs CK, Karlo JC, Kao SC, Landreth GE (2001) Beta-amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis. J Neurosci 21(4):1179-1188
20. Hensley K, Robinson KA, Gabbita SP, Salsman S, Floyd RA (2000) Reactive oxygen species, cell signaling, and cell injury. Free Radic Biol Med 28(10):1456-1462
21. McCulloch V, Seidel-Rogol BL, Shadel GS (2002) A human mitochondrial transcription factor is related to RNA adenine methyltransferases and binds S-adenosylmethionine. Mol Cell Biol 22(4):1116-1125
22. de las Cuevas N, Munoz U, Hermida OG, Martin-Requero A (2005) Altered transcriptional regulators in response to serum in immortalized lymphocytes from Alzheimer's disease patients. Neurobiol Aging 26(5):615-624
23. da Silva AM, Payao SL, Borsatto B, Bertolucci PH, Smith MA (2000) Quantitative evaluation of the rRNA in Alzheimer's disease. Mech Ageing Dev 120(1-3):57-64
24. Larsson NG, Wang J, Wilhelmsson H, Oldfors A, Rustin P, Lewandoski M, Barsh GS, Clayton DA (1998) Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat Genet 18(3):231-236