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Volumn 56, Issue 7, 2007, Pages 1865-1871

Hypoglycemic action of thiazolidinediones/peroxisome proliferator-activated receptor γ by inhibition of the c-Jun NH2-terminal kinase pathway

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; INTERLEUKIN 1BETA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; STRESS ACTIVATED PROTEIN KINASE; TROGLITAZONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 34347369726     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-1293     Document Type: Article
Times cited : (54)

References (43)
  • 2
    • 0035905772 scopus 로고    scopus 로고
    • The missing link with obesity?
    • Flier JS: The missing link with obesity? Nature 409:292-293, 2001
    • (2001) Nature , vol.409 , pp. 292-293
    • Flier, J.S.1
  • 3
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    • Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM: IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271:665-668, 1996
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 4
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L, Karin M: Mammalian MAP kinase signalling cascades. Nature 410:37-40, 2001
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 9
    • 0033850451 scopus 로고    scopus 로고
    • The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic β-cells
    • Ammendrup A, Maillard A, Nielsen K, Andersen NA, Serup P, Madsen OD, Mandrup-Poulsen T, Bonny C: The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic β-cells. Diabetes 49:1468-1476, 2000
    • (2000) Diabetes , vol.49 , pp. 1468-1476
    • Ammendrup, A.1    Maillard, A.2    Nielsen, K.3    Andersen, N.A.4    Serup, P.5    Madsen, O.D.6    Mandrup-Poulsen, T.7    Bonny, C.8
  • 12
    • 0038460622 scopus 로고    scopus 로고
    • Thiazolidinediones in type 2 diabetes mellitus
    • Diamant M, Heine RJ: Thiazolidinediones in type 2 diabetes mellitus. Drugs 63:1373-1405, 2003
    • (2003) Drugs , vol.63 , pp. 1373-1405
    • Diamant, M.1    Heine, R.J.2
  • 13
    • 0030885575 scopus 로고    scopus 로고
    • Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling
    • Peraldi P, Xu M, Spiegelman BM: Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling. J Clin Invest 100:1863-1869, 1997
    • (1997) J Clin Invest , vol.100 , pp. 1863-1869
    • Peraldi, P.1    Xu, M.2    Spiegelman, B.M.3
  • 14
    • 0035029255 scopus 로고    scopus 로고
    • Pioglitazone ameliorates tumor necrosis factor-α-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator-activated receptor-γ
    • Iwata M, Haruta T, Usui I, Takata Y, Takano A, Uno T, Kawahara J, Ueno E, Sasaoka T, Ishibashi O, Kobayashi M: Pioglitazone ameliorates tumor necrosis factor-α-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator-activated receptor-γ. Diabetes 50:1083-1092, 2001
    • (2001) Diabetes , vol.50 , pp. 1083-1092
    • Iwata, M.1    Haruta, T.2    Usui, I.3    Takata, Y.4    Takano, A.5    Uno, T.6    Kawahara, J.7    Ueno, E.8    Sasaoka, T.9    Ishibashi, O.10    Kobayashi, M.11
  • 15
    • 0030661983 scopus 로고    scopus 로고
    • TNF-α-induced insulin resistance in vivo and its prevention by troglitazone
    • Miles PDG, Romeo OM, Higo K, Cohen A, Rafaat K, Olefsky JM: TNF-α-induced insulin resistance in vivo and its prevention by troglitazone. Diabetes 46:1678-1683, 1997
    • (1997) Diabetes , vol.46 , pp. 1678-1683
    • Miles, P.D.G.1    Romeo, O.M.2    Higo, K.3    Cohen, A.4    Rafaat, K.5    Olefsky, J.M.6
  • 16
    • 0037883037 scopus 로고    scopus 로고
    • Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients
    • Miyazaki Y, He H, Mandarino LJ, DeFronzo RA: Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients. Diabetes 52:1943-1950, 2003
    • (2003) Diabetes , vol.52 , pp. 1943-1950
    • Miyazaki, Y.1    He, H.2    Mandarino, L.J.3    DeFronzo, R.A.4
  • 17
  • 18
    • 22644440448 scopus 로고    scopus 로고
    • β-Cell preservation: A potential role for thiazolidinediones to improve clinical care in type 2 diabetes
    • Leiter LA: β-Cell preservation: a potential role for thiazolidinediones to improve clinical care in type 2 diabetes. Diabet Med 22:963-972, 2005
    • (2005) Diabet Med , vol.22 , pp. 963-972
    • Leiter, L.A.1
  • 20
    • 0346880507 scopus 로고    scopus 로고
    • Role of PPARs in the regulation of obesity-related insulin sensitivity and inflammation
    • Moller DE, Berger JP: Role of PPARs in the regulation of obesity-related insulin sensitivity and inflammation. Int J Obes 27:S17-S21, 2003
    • (2003) Int J Obes , vol.27
    • Moller, D.E.1    Berger, J.P.2
  • 22
    • 0035851187 scopus 로고    scopus 로고
    • PPAR-γ: A nuclear receptor of metabolism, differentiation and cell growth
    • Rosen ED, Spiegelman BM: PPAR-γ: a nuclear receptor of metabolism, differentiation and cell growth. J Biol Chem 276:37731-37734, 2001
    • (2001) J Biol Chem , vol.276 , pp. 37731-37734
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 23
    • 0028972025 scopus 로고    scopus 로고
    • 2 is a ligand for the adipocyte determination factor PPARγ. Cell 83:803-812, 1995
    • 2 is a ligand for the adipocyte determination factor PPARγ. Cell 83:803-812, 1995
  • 27
    • 0029745382 scopus 로고    scopus 로고
    • Thiazolidinediones produce a conformational change in peroxisome proliferator-activated receptor gamma: Binding and activation correlate with antidiabetic actions in db/db mice
    • Berger J, Bailey P, Biswas C, Cullinan CA, Doebber TW, Hayes NS, Saperstein R, Smith RG, Leibowitz MD: Thiazolidinediones produce a conformational change in peroxisome proliferator-activated receptor gamma: binding and activation correlate with antidiabetic actions in db/db mice. Endocrinology 137:4189-4195, 1996
    • (1996) Endocrinology , vol.137 , pp. 4189-4195
    • Berger, J.1    Bailey, P.2    Biswas, C.3    Cullinan, C.A.4    Doebber, T.W.5    Hayes, N.S.6    Saperstein, R.7    Smith, R.G.8    Leibowitz, M.D.9
  • 28
    • 0842291578 scopus 로고    scopus 로고
    • Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells
    • Merglen A, Theander S, Rubi B, Chaffard G, Wollheim CB, Maechler P: Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. Endocrinology 145:667-678, 2004
    • (2004) Endocrinology , vol.145 , pp. 667-678
    • Merglen, A.1    Theander, S.2    Rubi, B.3    Chaffard, G.4    Wollheim, C.B.5    Maechler, P.6
  • 29
    • 4544350908 scopus 로고    scopus 로고
    • Assays to measure stress-activated mitogen-activated protein kinase activity
    • Brady HJM, Ed. Totowa, NJ, Humana Press
    • Caelles C, Morales M: Assays to measure stress-activated mitogen-activated protein kinase activity. In Apoptosis Methods and Protocols. Brady HJM, Ed. Totowa, NJ, Humana Press, 2004, p. 145-156
    • (2004) Apoptosis Methods and Protocols , pp. 145-156
    • Caelles, C.1    Morales, M.2
  • 30
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ). J Biol Chem 270:12953-12956, 1995
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 33
    • 2642683510 scopus 로고    scopus 로고
    • Differential regulation of insulin receptor substrate-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse
    • Kerouz NJ, Hörsch D, Ponsm S, Kahn CR: Differential regulation of insulin receptor substrate-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse. J Clin Invest 100:3164-3172, 1997
    • (1997) J Clin Invest , vol.100 , pp. 3164-3172
    • Kerouz, N.J.1    Hörsch, D.2    Ponsm, S.3    Kahn, C.R.4
  • 34
    • 7044260753 scopus 로고    scopus 로고
    • Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-α-deficient mice on a highfat diet
    • Matsui J, Terauchi Y, Kubota N, Takamoto I, Eto K, Yamashita T, Komeda K, Yamauchi T, Kamon J, Kita S, Noda M, Kadowaki T: Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-α-deficient mice on a highfat diet. Diabetes 53:2844-2854, 2004
    • (2004) Diabetes , vol.53 , pp. 2844-2854
    • Matsui, J.1    Terauchi, Y.2    Kubota, N.3    Takamoto, I.4    Eto, K.5    Yamashita, T.6    Komeda, K.7    Yamauchi, T.8    Kamon, J.9    Kita, S.10    Noda, M.11    Kadowaki, T.12
  • 35
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Wilson TM, Kelly CJ, Glass CK: The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391:79-82, 1998
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Wilson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 36
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C, Ting AT, Seed B: PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391:82-86, 1998
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 37
    • 0031455626 scopus 로고    scopus 로고
    • Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway
    • Caelles C, González-Sancho JM, Muñoz A: Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway. Genes Dev 11:3351-3364, 1997
    • (1997) Genes Dev , vol.11 , pp. 3351-3364
    • Caelles, C.1    González-Sancho, J.M.2    Muñoz, A.3
  • 38
    • 0344874677 scopus 로고    scopus 로고
    • Glucocorticoid receptor-JNK interaction mediates inhibition of the JNK pathway by glucocorticoids
    • Bruna A, Nicolàs M, Muñoz A, Kyriakis JM, Caelles C: Glucocorticoid receptor-JNK interaction mediates inhibition of the JNK pathway by glucocorticoids. EMBO J 22:6035-6044, 2003
    • (2003) EMBO J , vol.22 , pp. 6035-6044
    • Bruna, A.1    Nicolàs, M.2    Muñoz, A.3    Kyriakis, J.M.4    Caelles, C.5
  • 42
    • 0032894240 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-g1 and negatively regulates its transcriptional activity
    • Camp HS, Tafuri SR, Leff T: c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-g1 and negatively regulates its transcriptional activity. Endocrinology 140:392-397, 1999
    • (1999) Endocrinology , vol.140 , pp. 392-397
    • Camp, H.S.1    Tafuri, S.R.2    Leff, T.3
  • 43
    • 21244431989 scopus 로고    scopus 로고
    • The JNK pathway as a therapeutic target for diabetes
    • Kaneto H: The JNK pathway as a therapeutic target for diabetes. Expert Opin Ther Targets 9:581-592, 2005
    • (2005) Expert Opin Ther Targets , vol.9 , pp. 581-592
    • Kaneto, H.1


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