-
1
-
-
0141748121
-
Nicotinic acetylcholine receptors of muscles and nerves: Comparison of their structures, functional roles, and vulnerability to pathology
-
Lindstrom J. M. (2003) Nicotinic acetylcholine receptors of muscles and nerves: comparison of their structures, functional roles, and vulnerability to pathology. Ann. N. Y. Acad. Sci. 998, 41-52.
-
(2003)
Ann. N. Y. Acad. Sci
, vol.998
, pp. 41-52
-
-
Lindstrom, J.M.1
-
2
-
-
0036771570
-
A receptor assembly and trafficking: Implications for the modulation of inhibitory neurotransmission
-
A receptor assembly and trafficking: implications for the modulation of inhibitory neurotransmission. Mol. Neurobiol. 26, 251-268.
-
(2002)
Mol. Neurobiol
, vol.26
, pp. 251-268
-
-
Kittler, J.T.1
McAinsh, K.2
Moss, S.J.3
-
3
-
-
14844323722
-
Variations on an inhibitory theme: Phasic and tonic activation of GABA(A) receptors
-
Farrant M. and Nusser Z. (2005) Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors. Nat. Rev. Neurosci. 6, 215-229.
-
(2005)
Nat. Rev. Neurosci
, vol.6
, pp. 215-229
-
-
Farrant, M.1
Nusser, Z.2
-
5
-
-
13044283438
-
theta, a novel gamma-aminobutyric acid type A receptor subunit
-
Bonnert T. P., McKernan R. M., Farrar S., et al. (1999) theta, a novel gamma-aminobutyric acid type A receptor subunit. Proc. Natl. Acad. Sci. U. S. A. 96, 9891-9896.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A
, vol.96
, pp. 9891-9896
-
-
Bonnert, T.P.1
McKernan, R.M.2
Farrar, S.3
-
6
-
-
0032866465
-
Incorporation of the pi subunit into functional gamma-aminobutyric Acid(A) receptors
-
Neelands T. R. and Macdonald R. L. (1999) Incorporation of the pi subunit into functional gamma-aminobutyric Acid(A) receptors. Mol. Pharmacol. 56, 598-610.
-
(1999)
Mol. Pharmacol
, vol.56
, pp. 598-610
-
-
Neelands, T.R.1
Macdonald, R.L.2
-
7
-
-
0037289747
-
Alternate stoichiometries of alpha4beta2 nicotinic acetylcholine receptors
-
Nelson M. E., Kuryatov A., Choi C. H., Zhou Y., and Lindstrom J. (2003) Alternate stoichiometries of alpha4beta2 nicotinic acetylcholine receptors. Mol. Pharmacol. 63, 332-341.
-
(2003)
Mol. Pharmacol
, vol.63
, pp. 332-341
-
-
Nelson, M.E.1
Kuryatov, A.2
Choi, C.H.3
Zhou, Y.4
Lindstrom, J.5
-
9
-
-
0035965267
-
Subunit arrangement of gamma-aminobutyric acid type A receptors
-
Baumann S. W., Baur R., and Sigel E. (2001) Subunit arrangement of gamma-aminobutyric acid type A receptors. J. Biol. Chem. 276, 36,275-36,280.
-
(2001)
J. Biol. Chem
, vol.276
-
-
Baumann, S.W.1
Baur, R.2
Sigel, E.3
-
10
-
-
0035042719
-
Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment
-
Horenstein J., Wagner D. A., Czajkowski C., and Akabas M. H. (2001) Protein mobility and GABA-induced conformational changes in GABA(A) receptor pore-lining M2 segment. Nat. Neurosci. 4, 477-485.
-
(2001)
Nat. Neurosci
, vol.4
, pp. 477-485
-
-
Horenstein, J.1
Wagner, D.A.2
Czajkowski, C.3
Akabas, M.H.4
-
14
-
-
0036673411
-
Subunit Composition, Distribution and Function of GABA(A) Receptor Subtypes
-
Sieghart W. and Sperk G. (2002) Subunit Composition, Distribution and Function of GABA(A) Receptor Subtypes. Curr. Top. Med. Chem. 2, 795-816.
-
(2002)
Curr. Top. Med. Chem
, vol.2
, pp. 795-816
-
-
Sieghart, W.1
Sperk, G.2
-
16
-
-
2442666598
-
Positioning of the alpha-subunit isoforms confers a functional signature to gamma-aminobutyric acid type A-receptors
-
Minier F. and Sigel E. (2004) Positioning of the alpha-subunit isoforms confers a functional signature to gamma-aminobutyric acid type A-receptors. Proc. Natl. Acad. Sci. U. S. A. 101, 7769-7774.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A
, vol.101
, pp. 7769-7774
-
-
Minier, F.1
Sigel, E.2
-
17
-
-
10144229353
-
New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome
-
Engel A. G., Ohno K., Milone M., et al. (1996) New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome. Hum. Mol. Genet. 5, 1217-1227.
-
(1996)
Hum. Mol. Genet
, vol.5
, pp. 1217-1227
-
-
Engel, A.G.1
Ohno, K.2
Milone, M.3
-
18
-
-
0032829753
-
Hyperekplexia phenotype due to compound heterozygosity for GLRA1 gene mutations
-
Vergouwe M. N., Tijssen M. A., Peters A. C., Wielaard R., and Frants R. R. (1999) Hyperekplexia phenotype due to compound heterozygosity for GLRA1 gene mutations. Ann. Neurol. 46, 634-638.
-
(1999)
Ann. Neurol
, vol.46
, pp. 634-638
-
-
Vergouwe, M.N.1
Tijssen, M.A.2
Peters, A.C.3
Wielaard, R.4
Frants, R.R.5
-
19
-
-
3042599918
-
The juvenile myoclonic epilepsy GABA(A) receptor alpha1 subunit mutation A322D produces asymmetrical, subunit position-dependent reduction of heterozygous receptor currents and alpha1 subunit protein expression
-
Gallagher M. J., Song L., Arain F., and Macdonald R. L. (2004) The juvenile myoclonic epilepsy GABA(A) receptor alpha1 subunit mutation A322D produces asymmetrical, subunit position-dependent reduction of heterozygous receptor currents and alpha1 subunit protein expression. J. Neurosci. 24, 5570-5578.
-
(2004)
J. Neurosci
, vol.24
, pp. 5570-5578
-
-
Gallagher, M.J.1
Song, L.2
Arain, F.3
Macdonald, R.L.4
-
23
-
-
0024477606
-
Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology
-
Pritchett D. B., Sontheimer H., Shivers B. D., et al. (1989) Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology. Nature. 338, 582-585.
-
(1989)
Nature
, vol.338
, pp. 582-585
-
-
Pritchett, D.B.1
Sontheimer, H.2
Shivers, B.D.3
-
24
-
-
0348010294
-
Individual properties of the two functional agonist sites in GABA(A) receptors
-
Baumann S. W., Baur R., and Sigel E. (2003) Individual properties of the two functional agonist sites in GABA(A) receptors. J. Neurosci. 23, 11,158-11,166.
-
(2003)
J. Neurosci
, vol.23
-
-
Baumann, S.W.1
Baur, R.2
Sigel, E.3
-
25
-
-
5444253356
-
A receptor gamma2 subunit R43Q mutation linked to childhood absence epilepsy and febrile seizures causes retention of alpha1beta2 gamma2S receptors in the endoplasmic reticulum
-
A receptor gamma2 subunit R43Q mutation linked to childhood absence epilepsy and febrile seizures causes retention of alpha1beta2 gamma2S receptors in the endoplasmic reticulum. J. Neurosci. 24, 8672-8677.
-
(2004)
J. Neurosci
, vol.24
, pp. 8672-8677
-
-
Kang, J.Q.1
Macdonald, R.L.2
-
26
-
-
15744392087
-
A receptors induced by either agonist binding site
-
A receptors induced by either agonist binding site. Mol. Pharmacol. 67, 1005-1008.
-
(2005)
Mol. Pharmacol
, vol.67
, pp. 1005-1008
-
-
Baur, R.1
Sigel, E.2
-
27
-
-
33749341551
-
Mechanism of action of benzodiazepines on GABA(A) receptors
-
Campo-Soria C., Chang Y., and Weiss D. S. (2006) Mechanism of action of benzodiazepines on GABA(A) receptors. Br. J. Pharmacol. 148, 984-990.
-
(2006)
Br. J. Pharmacol
, vol.148
, pp. 984-990
-
-
Campo-Soria, C.1
Chang, Y.2
Weiss, D.S.3
-
28
-
-
0033004375
-
Structure and subunit composition of GABA(A) receptors
-
Sieghart W., Fuchs K., Tretter V., et al. (1999) Structure and subunit composition of GABA(A) receptors. Neurochem. Int. 34, 379-385.
-
(1999)
Neurochem. Int
, vol.34
, pp. 379-385
-
-
Sieghart, W.1
Fuchs, K.2
Tretter, V.3
-
29
-
-
29144529162
-
Consequence of the presence of two different beta subunit isoforms in a GABA(A) receptor
-
Boulineau N., Baur R., Minier F., and Sigel E. (2005) Consequence of the presence of two different beta subunit isoforms in a GABA(A) receptor. J. Neurochem. 95, 1724-1731.
-
(2005)
J. Neurochem
, vol.95
, pp. 1724-1731
-
-
Boulineau, N.1
Baur, R.2
Minier, F.3
Sigel, E.4
-
30
-
-
14644414132
-
The beta subunit determines the ligand binding properties of synaptic glycine receptors
-
Grudzinska J., Schemm R., Haeger S., et al. (2005) The beta subunit determines the ligand binding properties of synaptic glycine receptors. Neuron. 45, 727-739.
-
(2005)
Neuron
, vol.45
, pp. 727-739
-
-
Grudzinska, J.1
Schemm, R.2
Haeger, S.3
-
31
-
-
0346258343
-
Stoichiometry of recombinant heteromeric glycine receptors revealed by a pore-lining region point mutation
-
Burzomato V., Groot-Kormelink P. J., Sivilotti L. G., and Beato M. (2003) Stoichiometry of recombinant heteromeric glycine receptors revealed by a pore-lining region point mutation. Recept. Chan. 9, 353-361.
-
(2003)
Recept. Chan
, vol.9
, pp. 353-361
-
-
Burzomato, V.1
Groot-Kormelink, P.J.2
Sivilotti, L.G.3
Beato, M.4
-
32
-
-
0027716526
-
Assembly of the inhibitory glycine receptor: Identification of amino acid sequence motifs governing subunit stoichiometry
-
Kuhse J., Laube B., Magalei D., and Betz H. (1993) Assembly of the inhibitory glycine receptor: identification of amino acid sequence motifs governing subunit stoichiometry. Neuron. 11, 1049-1056.
-
(1993)
Neuron
, vol.11
, pp. 1049-1056
-
-
Kuhse, J.1
Laube, B.2
Magalei, D.3
Betz, H.4
-
33
-
-
0001202076
-
Conserved quaternary structure of ligand-gated ion channels: The postsynaptic glycine receptor is a pentamer
-
Langosch D., Thomas L., and Betz H. (1988) Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer. Proc. Natl. Acad. Sci. U. S. A. 85, 7394-7398.
-
(1988)
Proc. Natl. Acad. Sci. U. S. A
, vol.85
, pp. 7394-7398
-
-
Langosch, D.1
Thomas, L.2
Betz, H.3
-
34
-
-
0025734108
-
Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain
-
Malosio M. L., Marqueze-Pouey B., Kuhse J., and Betz H. (1991) Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain. Embo J. 10, 2401-2409.
-
(1991)
Embo J
, vol.10
, pp. 2401-2409
-
-
Malosio, M.L.1
Marqueze-Pouey, B.2
Kuhse, J.3
Betz, H.4
-
35
-
-
31044443411
-
Constraining the expression of nicotinic acetylcholine receptors by using pentameric constructs
-
Groot-Kormelink P. J., Broadbent S., Beato M., and Sivilotti L. G. (2006) Constraining the expression of nicotinic acetylcholine receptors by using pentameric constructs. Mol. Pharmacol. 69, 558-563.
-
(2006)
Mol. Pharmacol
, vol.69
, pp. 558-563
-
-
Groot-Kormelink, P.J.1
Broadbent, S.2
Beato, M.3
Sivilotti, L.G.4
-
36
-
-
0141919612
-
Human alpha4beta2 acetylcholine receptors formed from linked subunits
-
Zhou Y., Nelson M. E., Kuryatov A., Choi C., Cooper J., and Lindstrom J. (2003) Human alpha4beta2 acetylcholine receptors formed from linked subunits. J. Neurosci. 23, 9004-9015.
-
(2003)
J. Neurosci
, vol.23
, pp. 9004-9015
-
-
Zhou, Y.1
Nelson, M.E.2
Kuryatov, A.3
Choi, C.4
Cooper, J.5
Lindstrom, J.6
-
37
-
-
2942654670
-
Incomplete incorporation of tandem subunits in recombinant neuronal nicotinic receptors
-
Groot-Kormelink P. J., Broadbent S. D., Boorman J. P., and Sivilotti L. G. (2004) Incomplete incorporation of tandem subunits in recombinant neuronal nicotinic receptors. J. Gen. Physiol. 123, 697-708.
-
(2004)
J. Gen. Physiol
, vol.123
, pp. 697-708
-
-
Groot-Kormelink, P.J.1
Broadbent, S.D.2
Boorman, J.P.3
Sivilotti, L.G.4
-
38
-
-
33344471466
-
AGABA(A) receptor of defined subunit composition and positioning: Concatenation of five subunits
-
Baur R., Minier F., and Sigel E. (2006) AGABA(A) receptor of defined subunit composition and positioning: concatenation of five subunits. FEBS Lett. 580, 1616-1620.
-
(2006)
FEBS Lett
, vol.580
, pp. 1616-1620
-
-
Baur, R.1
Minier, F.2
Sigel, E.3
-
39
-
-
0032705299
-
Contribution of individual subunits to the multimeric P2X(2) receptor: Estimates based on methanethiosulfonate block at T336C
-
Stoop R., Thomas S., Rassendren F., et al. (1999) Contribution of individual subunits to the multimeric P2X(2) receptor: estimates based on methanethiosulfonate block at T336C. Mol. Pharmacol. 56, 973-981.
-
(1999)
Mol. Pharmacol
, vol.56
, pp. 973-981
-
-
Stoop, R.1
Thomas, S.2
Rassendren, F.3
-
40
-
-
0030739464
-
Random coil conformation for extended polyglutamine stretches in aqueous soluble monomeric peptides
-
Altschuler E. L., Hud N. V., Mazrimas J. A., and Rupp B. (1997) Random coil conformation for extended polyglutamine stretches in aqueous soluble monomeric peptides. J. Pept. Res. 50, 73-75.
-
(1997)
J. Pept. Res
, vol.50
, pp. 73-75
-
-
Altschuler, E.L.1
Hud, N.V.2
Mazrimas, J.A.3
Rupp, B.4
-
41
-
-
4344568965
-
Techniques: Use of concatenated subunits for the study of ligandgated ion channels
-
Minier F. and Sigel E. (2004) Techniques: Use of concatenated subunits for the study of ligandgated ion channels. Trends Pharmacol. Sci. 25, 499-503.
-
(2004)
Trends Pharmacol. Sci
, vol.25
, pp. 499-503
-
-
Minier, F.1
Sigel, E.2
-
42
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
Miyazawa A., Fujiyoshi Y., and Unwin N. (2003) Structure and gating mechanism of the acetylcholine receptor pore. Nature. 423, 949-955.
-
(2003)
Nature
, vol.423
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
43
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4A resolution
-
Unwin N. (2005) Refined structure of the nicotinic acetylcholine receptor at 4A resolution. J. Mol. Biol. 346, 967-989.
-
(2005)
J. Mol. Biol
, vol.346
, pp. 967-989
-
-
Unwin, N.1
-
44
-
-
23744445277
-
Benzodiazepine modulation of partial agonist efficacy and spontaneously active GABA(A) receptors supports an allosteric model of modulation
-
Downing S. S., Lee Y. T., Farb D. H., and Gibbs T. T. (2005) Benzodiazepine modulation of partial agonist efficacy and spontaneously active GABA(A) receptors supports an allosteric model of modulation. Br. J. Pharmacol. 145, 894-906.
-
(2005)
Br. J. Pharmacol
, vol.145
, pp. 894-906
-
-
Downing, S.S.1
Lee, Y.T.2
Farb, D.H.3
Gibbs, T.T.4
-
45
-
-
0029955444
-
Endogenous subunits can cause ambiguities in the pharmacology of exogenous gamma-aminobutyric acidA receptors expressed in human embryonic kidney 293 cells
-
Ueno S., Zorumski C., Bracamontes J., and Steinbach J. H. (1996) Endogenous subunits can cause ambiguities in the pharmacology of exogenous gamma-aminobutyric acidA receptors expressed in human embryonic kidney 293 cells. Mol. Pharmacol. 50, 931-938.
-
(1996)
Mol. Pharmacol
, vol.50
, pp. 931-938
-
-
Ueno, S.1
Zorumski, C.2
Bracamontes, J.3
Steinbach, J.H.4
-
46
-
-
3042818495
-
Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses
-
Luscher B. and Keller C. A. (2004) Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses. Pharmacol. Ther. 102, 195-221.
-
(2004)
Pharmacol. Ther
, vol.102
, pp. 195-221
-
-
Luscher, B.1
Keller, C.A.2
-
47
-
-
0042067949
-
Assembly and subunit diversity of nicotinic acetylcholine receptors
-
Millar N. S. (2003) Assembly and subunit diversity of nicotinic acetylcholine receptors. Biochem. Soc. Trans. 31, 869-874.
-
(2003)
Biochem. Soc. Trans
, vol.31
, pp. 869-874
-
-
Millar, N.S.1
-
48
-
-
0012118448
-
Structure and functions of inhibitory and excitatory glycine receptors
-
Betz H., Kuhse J., Schmieden V., Laube B., Kirsch J., and Harvey R. J. (1999) Structure and functions of inhibitory and excitatory glycine receptors. Ann. N. Y. Acad. Sci. 868, 667-676.
-
(1999)
Ann. N. Y. Acad. Sci
, vol.868
, pp. 667-676
-
-
Betz, H.1
Kuhse, J.2
Schmieden, V.3
Laube, B.4
Kirsch, J.5
Harvey, R.J.6
-
49
-
-
24644503580
-
Atomic force microscopy reveals the stoichiometry and subunit arrangement of 5-HT3 receptors
-
Barrera N. P., Herbert P., Henderson R. M., Martin I. L., and Edwardson J. M. (2005) Atomic force microscopy reveals the stoichiometry and subunit arrangement of 5-HT3 receptors. Proc. Natl. Acad. Sci. U. S. A. 102, 12,595-12,600.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A
, vol.102
-
-
Barrera, N.P.1
Herbert, P.2
Henderson, R.M.3
Martin, I.L.4
Edwardson, J.M.5
-
50
-
-
0029859799
-
Binding sites contribute unequally to the gating of mouse nicotinic alpha D200N acetylcholine receptors
-
Akk G., Sine S., and Auerbach A. (1996) Binding sites contribute unequally to the gating of mouse nicotinic alpha D200N acetylcholine receptors. J. Physiol. 496, 185-196.
-
(1996)
J. Physiol
, vol.496
, pp. 185-196
-
-
Akk, G.1
Sine, S.2
Auerbach, A.3
-
51
-
-
33644520967
-
Charged residues in the alpha1 and beta2 pre-M1 regions involved in GABAA receptor activation
-
Mercado J. and Czajkowski C. (2006) Charged residues in the alpha1 and beta2 pre-M1 regions involved in GABAA receptor activation. J. Neurosci. 26, 2031-2040.
-
(2006)
J. Neurosci
, vol.26
, pp. 2031-2040
-
-
Mercado, J.1
Czajkowski, C.2
|