Random coil conformation for extended polyglutamine stretches in aqueous soluble monomeric peptides

Journal of Peptide Research

Volumn 50, Issue 1, 1997, Pages 73-75

  Altschuler, Eric Lewin ^a,b   Hud, Nicholas V ^a   Mazrimas, Joseph A ^a   Rupp, Bernhard ^a  

^a LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Huntingtin; Huntington's disease; Polyglutamine; Trinucleotide repeats

Indexed keywords

GLUTAMINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CIRCULAR DICHROISM; DEGENERATIVE DISEASE; DISEASE ASSOCIATION; HUNTINGTON CHOREA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; TRINUCLEOTIDE REPEAT;

EID: 0030739464     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.1997.tb00622.x     Document Type: Article

References (11)

1. Housman, D.E. (1995) Nature Genet. 8, 10-11
2. Trottier, Y., Lutz, Y., Stevanin, G., Imbert, G., Devys, D., Cancel, G., Saudou, F., Weber, C., David, G., Tora, L., Agid, Y., Brice, A. & Mandel, J.L. (1995) Nature 387, 403-405
3. Gerber, H.P., Seipel, K., Georgiev, O., Hofferer, M., Hug, M., Rusconi, S. & Schaffner, W. (1994) Science 263, 808-811
4. Jennings, C. (1995) Nature 378, 127
5. Krull, L.K., Wall, J.S., Zobel, H. & Dimler, R.J. (1965) Biochemistry 4, 626-632
6. Ishikawa, K. & Endo, T. (1990) J. Polym. Sci. Part A Polym. Chem. 28, 3525-3527
7. Perutz, M.F., Johnson, T., Suzuki, M. & Finch, J.T. (1994) Proc Natl. Acad. Sci. USA 91, 5355-5358
8. Greenfield, N. & Fasman, G.D. (1969) Biochemistry 8, 4108-4116
9. Marqusee, S., Robbins, V.H. & Baldwin, R.L. (1989) Proc. Natl. Acad. Sci. USA 86, 5286-5290
10. Lupu-Lotan, N., Yaron, A. & Berger, A. (1966) Biopolymers 4, 365-368
11. Adler, A.J., Hoving, R., Potter, J., Wells, M. & Fasman, G.D. (1968) J. Am. Chem. Soc. 90, 4736-4738