Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis

Nature Protocols

Volumn 2, Issue 2, 2007, Pages 317-321

  Dallinger, Doris ^a   Kappe, C Oliver ^a  

^a UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

MONASTROL; EG5 PROTEIN, XENOPUS; KINESIN; PYRIMIDINE DERIVATIVE; THIOKETONE; UNCLASSIFIED DRUG; XENOPUS PROTEIN;

ARTICLE; BIGINELLI REACTION; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CRYSTALLIZATION; DRUG PURIFICATION; DRUG PURITY; DRUG STRUCTURE; DRUG SYNTHESIS; FILTRATION; HEATING; INTERMETHOD COMPARISON; MICROWAVE RADIATION; PRECIPITATION; PRIORITY JOURNAL; REACTION TIME; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METHODOLOGY; SYNTHESIS;

CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FILTRATION; KINESIN; MICROWAVES; MOLECULAR STRUCTURE; PRECIPITATION; PYRIMIDINES; THIONES; XENOPUS PROTEINS;

EID: 34347250848     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2006.436     Document Type: Article

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