메뉴 건너뛰기




Volumn 54, Issue 3, 2007, Pages 181-188

Genetic tests for predicting the toxicity and efficacy of anticancer chemotherapy

Author keywords

Anticancer therapy; Efficacy; Genetic variability; Toxicity

Indexed keywords

5 FLUOROURIDINE MONOPHOSPHATE; 5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); 6 THIOURIC ACID; 7 ETHYL 10 HYDROXYCAMPTOTHECIN; ANTHRACYCLINE DERIVATIVE; ANTILEUKEMIC AGENT; ANTINEOPLASTIC AGENT; BUSULFAN; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLOPHOSPHAMIDE; DIHYDROPYRIMIDINE DEHYDROGENASE; DOXORUBICIN; DOXORUBICIN IRON; DOXORUBICINOL; DRUG METABOLITE; DRUG METABOLIZING ENZYME; FLUOROURACIL; GLUCOCORTICOID; GLUCURONOSYLTRANSFERASE 1A1; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; IRINOTECAN; MERCAPTOPURINE; METHOTREXATE; PACLITAXEL; THIOGUANOSINE; THIOPURINE METHYLTRANSFERASE; THYMIDYLATE SYNTHASE; TIOGUANINE; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR; XANTHINE OXIDASE;

EID: 34347216743     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (9)

References (84)
  • 1
    • 18744377060 scopus 로고    scopus 로고
    • Clinical pharmacology of childhood ALL: Is the same dose optimal for everyone?
    • EVANS WE. Clinical pharmacology of childhood ALL: Is the same dose optimal for everyone? Med Ped Oncol 1999; 33: 191.
    • (1999) Med Ped Oncol , vol.33 , pp. 191
    • Evans, W.E.1
  • 3
    • 33744502855 scopus 로고    scopus 로고
    • Cancer biomarkers - An invitation to the table
    • DALTON WS, FRIEND SH. Cancer biomarkers - an invitation to the table. Science 2006; 312: 1165-1168.
    • (2006) Science , vol.312 , pp. 1165-1168
    • Dalton, W.S.1    Friend, S.H.2
  • 4
    • 0036906795 scopus 로고    scopus 로고
    • Future potential of thymidylate syntase inhibitors in cancer therapy
    • DOI 10.1517/13543784.11.12.1775
    • LEHMAN NL. Future potential of thymidylate synthase inhibitors in cancer therapy. Expert Opin Investig Drugs 2002; 11: 1775-1787. (Pubitemid 35469921)
    • (2002) Expert Opinion on Investigational Drugs , vol.11 , Issue.12 , pp. 1775-1787
    • Lehman, N.L.1
  • 5
    • 33645466805 scopus 로고    scopus 로고
    • Ashkenazi founder BRCA1/BRCA2 mutations in Slovak hereditary breast and/or ovarian cancer families
    • CIERNIKOVA S, TOMKA M, KOVAC M, STEVURKOVA V, ZAJAC V. Ashkenazi founder BRCA1/BRCA2 mutations in Slovak hereditary breast and/or ovarian cancer families. Neoplasma 2006; 53: 97-102.
    • (2006) Neoplasma , vol.53 , pp. 97-102
    • Ciernikova, S.1    Tomka, M.2    Kovac, M.3    Stevurkova, V.4    Zajac, V.5
  • 6
    • 33745876823 scopus 로고    scopus 로고
    • TP MT, UGT1A1 and DPYD: Genotyping to ensure safer cancer therapy?
    • Aug
    • MAITLAND ML, VASISHT K, RATAIN MJ. TP MT, UGT1A1 and DPYD: genotyping to ensure safer cancer therapy? Trends Pharmacol Sci 2006 Aug; 27: 432-437.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 432-437
    • Maitland, M.L.1    Vasisht, K.2    Ratain, M.J.3
  • 7
    • 27144505860 scopus 로고    scopus 로고
    • Tailored therapy of colorectal cancer: Results, challenges and future directions
    • GSAPARINI G, LONGO R, TORINO F, BARONE C, TOFFOLI G. Tailored therapy of colorectal cancer: results, challenges and future directions. Cancer J 2005; 11: 175-188. (Pubitemid 44698804)
    • (2005) Cancer Journal , vol.11 , Issue.3 , pp. 175-188
    • Gasparini, G.1    Longo, R.2    Torino, F.3    Barone, C.4    Toffoli, G.5
  • 8
    • 32944456234 scopus 로고    scopus 로고
    • Pharmacogenetics and pediatric cancer
    • Jul-Aug
    • BOMGAARS L, McLEOD HL. Pharmacogenetics and pediatric cancer. Cancer J 2005 Jul-Aug; 11: 314-323.
    • (2005) Cancer J , vol.11 , pp. 314-323
    • Bomgaars, L.1    McLeod, H.L.2
  • 9
    • 33644840600 scopus 로고    scopus 로고
    • Acute lymphoblastic leukaemia: A model for the pharmacogenomics of cancer therapy
    • CHEOK MH, EVANS WE. Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy. Nature Rev Cancer 2006; 6: 117-127.
    • (2006) Nature Rev Cancer , vol.6 , pp. 117-127
    • Cheok, M.H.1    Evans, W.E.2
  • 10
    • 23644448453 scopus 로고    scopus 로고
    • Personalised medicine for cancer: From drug development into clinical practice
    • DOI 10.1517/14656566.6.9.1463
    • JAIN KK. Personalised medicine for cancer: from drug development into clinical practice. Expert Opin Pharmacother 2005; 6: 1463-1476. (Pubitemid 41131687)
    • (2005) Expert Opinion on Pharmacotherapy , vol.6 , Issue.9 , pp. 1463-1476
    • Jain, K.K.1
  • 11
    • 0042914711 scopus 로고    scopus 로고
    • Homocystein, pharmacogenetics and neurotoxicity in children with leukemia
    • KISHI S, GRIENER J, CHENG CH et al. Homocystein, pharmacogenetics and neurotoxicity in children with leukemia. J Clin Oncol 2003; 21: 3084-3089.
    • (2003) J Clin Oncol , vol.21 , pp. 3084-3089
    • Kishi, S.1    Griener, J.2    Cheng, C.H.3
  • 12
    • 33746305081 scopus 로고    scopus 로고
    • Genetic polymorphism at GSTM1 and GSTT1 gene loci and susceptibility to oral cancer
    • SHARMA A, MISHRA A, DAS BC, SARDANA S, SHARMA JK. Genetic polymorphism at GSTM1 and GSTT1 gene loci and susceptibility to oral cancer. Neoplasma 2006; 53: 309-315. (Pubitemid 44105936)
    • (2006) Neoplasma , vol.53 , Issue.4 , pp. 309-315
    • Sharma, A.1    Mishra, A.2    Das, B.C.3    Sardana, S.4    Sharma, J.K.5
  • 13
    • 13844316592 scopus 로고    scopus 로고
    • Cancer pharmacogenomics: Powerful tools in cancer chemotherapy and drug development
    • LEE W, LOCKHART AC, KIM RB, ROTHENBERG ML. Cancer pharmacogenomics: Powerful tools in cancer chemotherapy and drug development. Oncologist 2005; 10: 104-111.
    • (2005) Oncologist , vol.10 , pp. 104-111
    • Lee, W.1    Lockhart, A.C.2    Kim, R.B.3    Rothenberg, M.L.4
  • 14
    • 0842286886 scopus 로고    scopus 로고
    • Cancer pharmacogenetics
    • MARSH S, McLEOD HL. Cancer pharmacogenetics. Br J Cancer 2004, 90: 8-11.
    • (2004) Br J Cancer , vol.90 , pp. 8-11
    • Marsh, S.1    McLeod, H.L.2
  • 15
    • 0032231751 scopus 로고    scopus 로고
    • Pharmacogenetics of cancer therapy: Getting personal
    • KRYNETSKI EY, EVANS WE. Pharmacogenetics of cancer therapy: getting personal. Am J Hum Genet 1998; 63: 11-16.
    • (1998) Am J Hum Genet , vol.63 , pp. 11-16
    • Krynetski, E.Y.1    Evans, W.E.2
  • 16
    • 4344604014 scopus 로고    scopus 로고
    • Pharmacogenomics in cancer therapy: Is host genome variability important?
    • PETROS WP, EVANS WE. Pharmacogenomics in cancer therapy: is host genome variability important ? Trends Pharmacol Sci 2004; 25: 457-464.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 457-464
    • Petros, W.P.1    Evans, W.E.2
  • 20
    • 33751120138 scopus 로고    scopus 로고
    • Perception of potentially inappropriate medication in elderly patients by Slovak physicians
    • in press
    • WAWRUCH M, ZIKAVSKA M, WSOLOVA L, JEZOVA D, FIALOVA D et al. Perception of potentially inappropriate medication in elderly patients by Slovak physicians. Pharmacoepidemiol Drug Saf 2006; 15: (in press).
    • (2006) Pharmacoepidemiol Drug Saf , vol.15
    • Wawruch, M.1    Zikavska, M.2    Wsolova, L.3    Jezova, D.4    Fialova, D.5
  • 22
    • 0344197480 scopus 로고    scopus 로고
    • Cancer pharmacogenetics: Polymorphisms, pathways and beyond
    • ULRICH CM, ROBIEN K, McLEOD HL. Cancer pharmacogenetics: polymorphisms, pathways and beyond. Nat Rev Cancer 2003; 3: 912-920.
    • (2003) Nat Rev Cancer , vol.3 , pp. 912-920
    • Ulrich, C.M.1    Robien, K.2    McLeod, H.L.3
  • 23
    • 0037446134 scopus 로고    scopus 로고
    • Targeted therapy and pharmacogenetic programs
    • IQBAL S, LENZ HJ. Targeted therapy and pharmacogenetic programs. Cancer 2003; 97: 2076-2078.
    • (2003) Cancer , vol.97 , pp. 2076-2078
    • Iqbal, S.1    Lenz, H.J.2
  • 25
    • 21344453004 scopus 로고    scopus 로고
    • Pharmacogenetics for individualized cancer chemotherapy
    • EFFERTH T, VOLM M. Pharmacogenetics for individualized cancer chemotherapy. Pharmacol Ther 2005; 107: 155-176.
    • (2005) Pharmacol Ther , vol.107 , pp. 155-176
    • Efferth, T.1    Volm, M.2
  • 26
    • 18744392678 scopus 로고    scopus 로고
    • Pharmacogenomics of chemotherapeutic agents in cancer treatment
    • Licinio J, Ma-Li Wong. Weinheim: Wiley-VCH Verlag
    • INNOCENTI I, IYER L, RATAIN MJ. Pharmacogenomics of chemotherapeutic agents in cancer treatment. In: Licinio J, Ma-Li Wong. Pharmacogenomics. The Search for Individualized Therapies. Weinheim: Wiley-VCH Verlag 2002a: 283-303.
    • (2002) Pharmacogenomics. The Search for Individualized Therapies , pp. 283-303
    • Innocenti, I.1    Iyer, L.2    Ratain, M.J.3
  • 29
    • 0041303650 scopus 로고    scopus 로고
    • Clinical implications of dihydropyrimidine dehydrogenase (DPD) activity in 5-FU-based chemotherapy: Mutations in the DPD gene, and DPD inhibitors fluoropyrimidines
    • OMURA K. Clinical implications of dihydropyrimidine dehydrogenase (DPD) activity in 5-FU-based chemotherapy: mutations in the DPD gene, and DPD inhibitors fluoropyrimidines. Int J Clin Oncol 2003; 8: 132-138.
    • (2003) Int J Clin Oncol , vol.8 , pp. 132-138
    • Omura, K.1
  • 30
  • 32
    • 33646564372 scopus 로고    scopus 로고
    • Interpreting disparate responses to cancer therapy: The role of human population genetics
    • [32) MAITLAND ML, DIRIENZO A, RATAIN MJ. Interpreting disparate responses to cancer therapy: the role of human population genetics. J Clin Oncol 2006; 24: 2151-2157.
    • (2006) J Clin Oncol , vol.24 , pp. 2151-2157
    • Maitland, M.L.1    Dirienzo, A.2    Ratain, M.J.3
  • 33
    • 0033486029 scopus 로고    scopus 로고
    • Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus
    • RELLING MV, HANCOCK ML, RIVERA GK, SANDLUND JT, RIBEIRO R et al. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus. J Natl Cancer Inst 1999a; 91: 2001-2008.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 2001-2008
    • Relling, M.V.1    Hancock, M.L.2    Rivera, G.K.3    Sandlund, J.T.4    Ribeiro, R.5
  • 34
    • 0033519986 scopus 로고    scopus 로고
    • High incidence of secondary brain tumours after radiotherapy and antimetabolites
    • RELLING MV, RUBNITZ JE, RIVERA GK, BOYETT JM, HANCOCK ML et al. High incidence of secondary brain tumours after radiotherapy and antimetabolites. Lancet 1999b; 354: 34-39.
    • (1999) Lancet , vol.354 , pp. 34-39
    • Relling, M.V.1    Rubnitz, J.E.2    Rivera, G.K.3    Boyett, J.M.4    Hancock, M.L.5
  • 36
    • 30444451921 scopus 로고    scopus 로고
    • Thiopurine methyltransferase in acute lymphoblastic leukemia [4]
    • DOI 10.1182/blood-2005-08-3379
    • RELLING MV, PUI CH, CHENG CH. Thiopurine methyl-transferase in acute lymphoblastic leukemia. Blood 2006; 107: 843-844. (Pubitemid 43076417)
    • (2006) Blood , vol.107 , Issue.2 , pp. 843-844
    • Relling, M.V.1    Pui, C.-H.2    Cheng, C.3    Evans, W.E.4
  • 37
    • 0028861745 scopus 로고
    • A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase
    • KRYNETSKI EY, SCHUETZ JD, GALPIN AJ et al. A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase. Proc Natl Acad Sci 1995; 92: 949-953.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 949-953
    • Krynetski, E.Y.1    Schuetz, J.D.2    Galpin, A.J.3
  • 38
  • 39
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • 286
    • EVANS WE, RELLING MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286, 1999; 5439: 487-491.
    • (1999) Science , vol.5439 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 40
    • 33750581390 scopus 로고    scopus 로고
    • Three novel thiopurine S-methyltransferase allelic variants (TPMT*20, *21, *22) - Association with decreased enzyme function
    • Sep
    • SCHAEFFELER E, EICHELBAUM M, REINISCH W, ZANGER UM, SCHWAB M. Three novel thiopurine S-methyltransferase allelic variants (TPMT*20, *21, *22) - association with decreased enzyme function. Hum Mutat 2006 Sep; 27(9): 976.
    • (2006) Hum Mutat , vol.27 , Issue.9 , pp. 976
    • Schaeffeler, E.1    Eichelbaum, M.2    Reinisch, W.3    Zanger, U.M.4    Schwab, M.5
  • 41
    • 0033828949 scopus 로고    scopus 로고
    • Genetic polymorphism of thiopurine S-methyltransferase: Molecular mechanisms and clinical importance
    • KRYNETSKI EY, EVANS WE. Genetic polymorphism of thiopurine S-methyltransferase: molecular mechanisms and clinical importance. Pharmacology 2000; 61: 136-146.
    • (2000) Pharmacology , vol.61 , pp. 136-146
    • Krynetski, E.Y.1    Evans, W.E.2
  • 42
    • 0242312707 scopus 로고    scopus 로고
    • Drug methylation in cancer therapy: Lessons from the TPMT polymorphism
    • 22
    • KRYNETSKI EY, EVANS WE.Drug methylation in cancer therapy: lessons from the TPMT polymorphism. Oncogene 22, 2003; 47: 7403-7413.
    • (2003) Oncogene , vol.47 , pp. 7403-7413
    • Krynetski, E.Y.1    Evans, W.E.2
  • 43
    • 0142240380 scopus 로고    scopus 로고
    • Preventing toxicity with a gene test
    • MARSHALL E. Preventing toxicity with a gene test. Science 2003; 302(5645): 588-590
    • (2003) Science , vol.302 , Issue.5645 , pp. 588-590
    • Marshall, E.1
  • 44
    • 0034034158 scopus 로고    scopus 로고
    • Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood lymphoblastic leukemia
    • McLEOD HL, KRYNETSKI EY, RELLING MV, EVANS WE. Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood lymphoblastic leukemia. Leukemia 2000; 14: 567-572.
    • (2000) Leukemia , vol.14 , pp. 567-572
    • McLeod, H.L.1    Krynetski, E.Y.2    Relling, M.V.3    Evans, W.E.4
  • 45
    • 0036009619 scopus 로고    scopus 로고
    • The thiopurine S-methyltransferase gene locus - Implications for clinical pharmacogenomics
    • McLEOD HL, SIVA C. The thiopurine S-methyltransferase gene locus - implications for clinical pharmacogenomics. Pharmacogenomics 2002; 3: 89-98.
    • (2002) Pharmacogenomics , vol.3 , pp. 89-98
    • McLeod, H.L.1    Siva, C.2
  • 46
    • 0036066914 scopus 로고    scopus 로고
    • Thiopurine methyltransferase polymorphism in a multiracial Asian population and children with acute lymphoblastic leukemia
    • KHAM SK, TAN PL, TAY AH, HENG CK, YEOH AF et al. Thiopurine methyltransferase polymorphism in a multiracial Asian population and children with acute lymphoblastic leukemia. J Pediatr Hematol Oncol 2002; 24: 353-359.
    • (2002) J Pediatr Hematol Oncol , vol.24 , pp. 353-359
    • Kham, S.K.1    Tan, P.L.2    Tay, A.H.3    Heng, C.K.4    Yeoh, A.F.5
  • 48
    • 0037134707 scopus 로고    scopus 로고
    • Association between glutathione s-transferase P1, T1, and M1 genetic polymorphism and surival of patients with metastatic colorectal caneer
    • Jun
    • STOEHLMACHER J, PARK DJ, ZHANG W et al. Association between glutathione s-transferase P1, T1, and M1 genetic polymorphism and surival of patients with metastatic colorectal caneer. J Natl Cancer Inst 2002 Jun; 94(12): 936-942.
    • (2002) J Natl Cancer Inst , vol.94 , Issue.12 , pp. 936-942
    • Stoehlmacher, J.1    Park, D.J.2    Zhang, W.3
  • 50
    • 33745008604 scopus 로고    scopus 로고
    • Pathogenesis of cardiotoxicity induced by anthracyclines
    • ELLIOTT P. Pathogenesis of cardiotoxicity induced by anthracyclines. Semin Oncol 2006; 33, Suppl 8: 2-7.
    • (2006) Semin Oncol , vol.33 , Issue.SUPPL. 8 , pp. 2-7
    • Elliott, P.1
  • 51
    • 0034164652 scopus 로고    scopus 로고
    • Late effects of anthracycline therapy in childhood on signal-averaged ECG parameters
    • Apr
    • MLADOSIEVIČOVÁ B, FOLTINOVÁ A, PETRÁŠ OVÁ H, HULÍN I. Late effects of anthracycline therapy in childhood on signal-averaged ECG parameters. Int J Mol Med 2000 Apr; 5: 411-414.
    • (2000) Int J Mol Med , vol.5 , pp. 411-414
    • Mladosievičová, B.1    Foltinová, A.2    Petráš ová, H.3    Hulín, I.4
  • 52
    • 0032965572 scopus 로고    scopus 로고
    • Role of iron in anthracycline cardiotoxicity: New tunes for an old song?
    • MINOTTI G, CAIRO G, MONTI E. Role of iron in anthracycline cardiotoxicity: new tunes for an old song? FASEB J 1999; 13: 199-212.
    • (1999) FASEB J , vol.13 , pp. 199-212
    • Minotti, G.1    Cairo, G.2    Monti, E.3
  • 53
    • 34548330602 scopus 로고    scopus 로고
    • Polymorphisms in candidate genes in patients with congestive heart failure (CHF) after childhood cancer: A Report from the Childhood Cancer Survivor Study (CCSS)
    • ASCO Annual Meeting Proceedings Part I.
    • APLENC R, BLANCO J, LEISENRING W et al. Polymorphisms in candidate genes in patients with congestive heart failure (CHF) after childhood cancer: A Report from the Childhood Cancer Survivor Study (CCSS). J Clin Oncol 2006; ASCO Annual Meeting Proceedings Part I., Vol 24 (June 20 Suppl): 9004.
    • (2006) J Clin Oncol , vol.24 , Issue.JUNE 20 SUPPL. , pp. 9004
    • Aplenc, R.1    Blanco, J.2    Leisenring, W.3
  • 54
    • 0018894446 scopus 로고
    • Degradation of pyrimidines and pyrimidine analogs - Pathways and mutual influences
    • WASTERNACK C. Degradation of pyrimidines and pyrimidine analogs - pathways and mutual influences. Pharmacol Ther 1980; 8: 629-652.
    • (1980) Pharmacol Ther , vol.8 , pp. 629-652
    • Wasternack, C.1
  • 55
    • 0023187085 scopus 로고
    • Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile
    • HEGGIE GD, SOMMADOSSI JP, CROSS DS, HUSTLER WJ, DIASIO RB. Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile. Cancer Res 1987; 47: 2203-2206. (Pubitemid 17074634)
    • (1987) Cancer Research , vol.47 , Issue.8 , pp. 2203-2206
    • Heggie, G.D.1    Sommadossi, J.-P.2    Cross, D.S.3
  • 56
    • 84906200654 scopus 로고    scopus 로고
    • Final results of a prospective multicenter study on the prevalence and genotype/phenotype correlation of the dihydropyrimidine dehydrogenase (DPD) gene exon-14 skipping mutation in patients treated with 5-fluorouracil (5-FU) chemotherapy
    • ASCO Annual Meeting Proceedings Part I., 2006
    • RAIDA M, FRIEDRICH A, BORRIS M, NIEDERWIESER D, BEHNKE D, KLICHE KO et al. Final results of a prospective multicenter study on the prevalence and genotype/phenotype correlation of the dihydropyrimidine dehydrogenase (DPD) gene exon-14 skipping mutation in patients treated with 5-fluorouracil (5-FU) chemotherapy. J Clin Oncol 2006, ASCO Annual Meeting Proceedings Part I., Vol 24 (18S) (June 20 Supplement), 2006: 3076
    • (2006) J Clin Oncol , vol.24 , Issue.18 S JUNE 20 SUPPL. , pp. 3076
    • Raida, M.1    Friedrich, A.2    Borris, M.3    Niederwieser, D.4    Behnke, D.5    Kliche, K.O.6
  • 57
    • 68949087331 scopus 로고    scopus 로고
    • Molecular basis of altered uracil catabolism in individuals with 5-FU toxicity and normal DPD enzyme activity
    • ASCO Annual Meeting Proceedings Part I., 2006
    • REED HA, EZZELDIN HH, MATTISON LK, DIASI RB. Molecular basis of altered uracil catabolism in individuals with 5-FU toxicity and normal DPD enzyme activity. J Clin Oncol 2006, ASCO Annual Meeting Proceedings Part I., Vol 24 (18S) (June 20 Supplement), 2006: 3070.
    • (2006) J Clin Oncol , vol.24 , Issue.18 S JUNE 20 SUPPL. , pp. 3070
    • Reed, H.A.1    Ezzeldin, H.H.2    Mattison, L.K.3    Diasi, R.B.4
  • 58
    • 33645120407 scopus 로고    scopus 로고
    • Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer
    • NAGAR S, REMMEL RP. Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer. Oncogene 2006; 25: 1659-1672.
    • (2006) Oncogene , vol.25 , pp. 1659-1672
    • Nagar, S.1    Remmel, R.P.2
  • 59
    • 0030580064 scopus 로고    scopus 로고
    • Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxy-camptothecin (SN-38), by human liver carboxylesterase
    • RIVORY L P, BOWLES M R, ROBERT J, POND S M. Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxy-camptothecin (SN-38), by human liver carboxylesterase. Biochem. Pharmacol 1996; 52: 1103-1111.
    • (1996) Biochem. Pharmacol , vol.52 , pp. 1103-1111
    • Rivory, L.P.1    Bowles, M.R.2    Robert, J.3    Pond, S.M.4
  • 60
    • 0028867826 scopus 로고
    • The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
    • BOSMA PJ, CHOWDHURY JR, BAKKER C, GANTLA S, DE BOER A et al. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 1995; 333: 1171-1175.
    • (1995) N Engl J Med , vol.333 , pp. 1171-1175
    • Bosma, P.J.1    Chowdhury, J.R.2    Bakker, C.3    Gantla, S.4    De Boer, A.5
  • 61
    • 0032493441 scopus 로고    scopus 로고
    • Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: A balanced polymorphism for regulation of bilirubin metabolism?
    • BEUTLER E, GELBART T, DEMINA A. Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism? Proc Natl Acad Sci USA 1998; 95: 8170-8174.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8170-8174
    • Beutler, E.1    Gelbart, T.2    Demina, A.3
  • 62
    • 12244271026 scopus 로고    scopus 로고
    • Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups
    • INNOCENTI F, GRIMSLEY D, DAS S, RAMIREZ J, CHENG C et al. Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups. Pharmacogenetics 2002b; 12: 725-733.
    • (2002) Pharmacogenetics , vol.12 , pp. 725-733
    • Innocenti, F.1    Grimsley, D.2    Das, S.3    Ramirez, J.4    Cheng, C.5
  • 63
    • 33750176033 scopus 로고    scopus 로고
    • Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer (FOCUS)
    • ASCO Annual Meeting Proceedings Part I., 2006
    • SEYMOUR MT, BRAUN MS, RICHMAN, SD et al. Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer (FOCUS). J Clin Oncol 2006, ASCO Annual Meeting Proceedings Part I., Vol 24 (18S) (June 20 Supplement), 2006: 2022.
    • (2006) J Clin Oncol , vol.24 , Issue.18 S JUNE 20 SUPPL. , pp. 2022
    • Seymour, M.T.1    Braun, M.S.2    Richman, S.D.3
  • 64
    • 84906171282 scopus 로고    scopus 로고
    • TYMS polymorphism analysis prediction of bolus 5-fluorouracil toxicity
    • ASCO Annual Meeting Proceedings Part I., 2006
    • GUSELLA M, BOLZONELLA C, BERTOLASO L et al. TYMS polymorphism analysis prediction of bolus 5-fluorouracil toxicity. J Clin Oncol 2006; ASCO Annual Meeting Proceedings Part I., Vol 24 (18S) (June 20 Suppl), 2006: 13022.
    • (2006) J Clin Oncol , vol.24 , Issue.18 S JUNE 20 SUPPL. , pp. 13022
    • Gusella, M.1    Bolzonella, C.2    Bertolaso, L.3
  • 65
    • 0036928840 scopus 로고    scopus 로고
    • Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate
    • CHIUSOLO P, REDDICONTO G, CASORELLI I, LAURENTI L, SORA F et al. Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate. Ann Oncol 2002; 13: 1915-1918.
    • (2002) Ann Oncol , vol.13 , pp. 1915-1918
    • Chiusolo, P.1    Reddiconto, G.2    Casorelli, I.3    Laurenti, L.4    Sora, F.5
  • 66
    • 0027842835 scopus 로고
    • Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals
    • BORST P, SCHINKEL AH, SMIT JJ, WAGENAAR E, VAN DEEMTER L et al. Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals. Pharmacol Ther 1993; 60: 289-299.
    • (1993) Pharmacol Ther , vol.60 , pp. 289-299
    • Borst, P.1    Schinkel, A.H.2    Smit, J.J.3    Wagenaar, E.4    Van Deemter, L.5
  • 67
    • 0031158805 scopus 로고    scopus 로고
    • The physiological function of drug-transporting P-glycoproteins
    • SCHINKEL AH. The physiological function of drug-transporting P-glycoproteins. Semin Cancer Biol 1997; 8: 161-170.
    • (1997) Semin Cancer Biol , vol.8 , pp. 161-170
    • Schinkel, A.H.1
  • 68
    • 0037362355 scopus 로고    scopus 로고
    • ATP binding cassette transporters and drug resistance in breast cancer
    • DOI 10.1677/erc.0.0100043
    • LEONESSA F, CLARKE R. ATP binding cassette transporters and drug resistance in breast cancer. Endocr Relat Cancer 2003; 10: 43-73. (Pubitemid 36457239)
    • (2003) Endocrine-Related Cancer , vol.10 , Issue.1 , pp. 43-73
    • Leonessa, F.1    Clarke, R.2
  • 69
    • 4644359707 scopus 로고    scopus 로고
    • Targeting the multidrug resistance-1 transporter in AML: Molecular regulation and therapeutic strategies
    • MAHADEVAN D, LIST AF. Targeting the multidrug resistance-1 transporter in AML: molecular regulation and therapeutic strategies. Blood 2004; 104: 1940-1951.
    • (2004) Blood , vol.104 , pp. 1940-1951
    • Mahadevan, D.1    List, A.F.2
  • 70
    • 33644860579 scopus 로고    scopus 로고
    • An update on overcoming MDR1-mediated multidrug resistance in cancer chemotherapy
    • TAKARA K, SAKAEDA T, OKUMURA K. An update on overcoming MDR1-mediated multidrug resistance in cancer chemotherapy. Curr Pharm Des 2006; 12: 273-286.
    • (2006) Curr Pharm des , vol.12 , pp. 273-286
    • Takara, K.1    Sakaeda, T.2    Okumura, K.3
  • 71
    • 0037110469 scopus 로고    scopus 로고
    • Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia
    • LAVERDIERE C, CHIASSON S, COSTEA I, MOGHRABI A, KRAJINOVIC M. Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia. Blood 2002; 100: 3832-3834.
    • (2002) Blood , vol.100 , pp. 3832-3834
    • Laverdiere, C.1    Chiasson, S.2    Costea, I.3    Moghrabi, A.4    Krajinovic, M.5
  • 72
    • 0038779673 scopus 로고    scopus 로고
    • Reduced folate carrier: Biochemistry and molecular biology of the normal and methotrexate-resistant cell
    • BOSSON G. Reduced folate carrier: biochemistry and molecular biology of the normal and methotrexate-resistant cell. Br J Biomed Sci 2003; 60: 117-129.
    • (2003) Br J Biomed Sci , vol.60 , pp. 117-129
    • Bosson, G.1
  • 73
    • 0034666338 scopus 로고    scopus 로고
    • Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: A report from the Children's Cancer Group
    • MATTANO LA JR, SATHER HN, TRIGG ME et al. Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: A report from the Children's Cancer Group. J Clin Oncol 2000; 18: 3262-3272.
    • (2000) J Clin Oncol , vol.18 , pp. 3262-3272
    • Mattano Jr., L.A.1    Sather, H.N.2    Trigg, M.E.3
  • 74
    • 68949092967 scopus 로고    scopus 로고
    • Possibility of late consequences of anticancer treatment in childhood
    • ISBN 80-8095-004-0 (in press)
    • MLADOSIEVICOVA B, KAISEROVA E, FOLTINOVA A. Possibility of late consequences of anticancer treatment in childhood. SAP 2007, ISBN 80-8095-004-0 (in press).
    • (2007) SAP
    • Mladosievicova, B.1    Kaiserova, E.2    Foltinova, A.3
  • 76
    • 5444266905 scopus 로고    scopus 로고
    • Pharmacogenetic risk factors for osteonecrosis of the hip among children with leukemia
    • RELLING MV, YANG W, DAS S et al. Pharmacogenetic risk factors for osteonecrosis of the hip among children with leukemia. J Clin Oncol 2004; 22 (11): 3930-3936.
    • (2004) J Clin Oncol , vol.22 , Issue.11 , pp. 3930-3936
    • Relling, M.V.1    Yang, W.2    Das, S.3
  • 77
    • 0034048729 scopus 로고    scopus 로고
    • Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
    • Apr
    • SALONGA D, DANENBERG KD, JOHNSON M et al. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin Cancer Res 2000 Apr; 6(4): 1322-1327.
    • (2000) Clin Cancer Res , vol.6 , Issue.4 , pp. 1322-1327
    • Salonga, D.1    Danenberg, K.D.2    Johnson, M.3
  • 78
    • 85047692068 scopus 로고    scopus 로고
    • Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics
    • KAGER L, CHEOK M, YANG W et al. Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics. J Clin Invest 2005; 115: 110-117.
    • (2005) J Clin Invest , vol.115 , pp. 110-117
    • Kager, L.1    Cheok, M.2    Yang, W.3
  • 79
    • 0033837696 scopus 로고    scopus 로고
    • Predicting response to chronic antihypertensive treatment with fosinopril: The role of angiotensin-converting enzyme gene polymorphism
    • STAVROULAKIS GA, MAKRIS TK, KRESPI PG et al. Predicting response to chronic antihypertensive treatment with fosinopril: the role of angiotensin-converting enzyme gene polymorphism. Cardiovasc Drug Ther 2000; 14: 427-432.
    • (2000) Cardiovasc Drug Ther , vol.14 , pp. 427-432
    • Stavroulakis, G.A.1    Makris, T.K.2    Krespi, P.G.3
  • 80
    • 0035052741 scopus 로고    scopus 로고
    • Effect of polymorphisms of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma
    • ISRAEL E, DRAZEN JM, LIGGETT SB et al. Effect of polymorphisms of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma. Int Arch Allergy Immunol 2001; 124: 183-186.
    • (2001) Int Arch Allergy Immunol , vol.124 , pp. 183-186
    • Israel, E.1    Drazen, J.M.2    Liggett, S.B.3
  • 81
    • 0034612110 scopus 로고    scopus 로고
    • Pharmacogenetic prediction of clozapine response
    • ARRANZ MJ, MUNRO J, BIRKETT J et al. Pharmacogenetic prediction of clozapine response. Lancet 2000; 355: 1615-1616.
    • (2000) Lancet , vol.355 , pp. 1615-1616
    • Arranz, M.J.1    Munro, J.2    Birkett, J.3
  • 82
    • 84906102254 scopus 로고    scopus 로고
    • Problems of pain medicine in pregradual medical and nursing teaching
    • in Slovak
    • BERNADIČ M., KULICHOVÁ M.: Problems of pain medicine in pregradual medical and nursing teaching. Reumatológia 2002; 16: 199-200 (in Slovak).
    • (2002) Reumatológia , vol.16 , pp. 199-200
    • Bernadič, M.1    Kulichová, M.2
  • 83
    • 0037187926 scopus 로고    scopus 로고
    • Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease
    • HERRINGTON DM, HOWARD TD, HAWKINS GA et al. Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease. N Engl J Med 2002; 346: 967-974.
    • (2002) N Engl J Med , vol.346 , pp. 967-974
    • Herrington, D.M.1    Howard, T.D.2    Hawkins, G.A.3
  • 84
    • 0037421590 scopus 로고    scopus 로고
    • Pharmacogenomics - Drug disposition, drug targets, and side effects
    • DOI 10.1056/NEJMra020526
    • EVANS WE, McLEOD HL. Pharmacogenomics-drug disposition, drug targets, and side effects. N Engl J Med 2003; 348:538-549. (Pubitemid 36159890)
    • (2003) New England Journal of Medicine , vol.348 , Issue.6 , pp. 538-549
    • Evans, W.E.1    McLeod, H.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.