-
1
-
-
18744377060
-
Clinical pharmacology of childhood ALL: Is the same dose optimal for everyone?
-
EVANS WE. Clinical pharmacology of childhood ALL: Is the same dose optimal for everyone? Med Ped Oncol 1999; 33: 191.
-
(1999)
Med Ped Oncol
, vol.33
, pp. 191
-
-
Evans, W.E.1
-
3
-
-
33744502855
-
Cancer biomarkers - An invitation to the table
-
DALTON WS, FRIEND SH. Cancer biomarkers - an invitation to the table. Science 2006; 312: 1165-1168.
-
(2006)
Science
, vol.312
, pp. 1165-1168
-
-
Dalton, W.S.1
Friend, S.H.2
-
4
-
-
0036906795
-
Future potential of thymidylate syntase inhibitors in cancer therapy
-
DOI 10.1517/13543784.11.12.1775
-
LEHMAN NL. Future potential of thymidylate synthase inhibitors in cancer therapy. Expert Opin Investig Drugs 2002; 11: 1775-1787. (Pubitemid 35469921)
-
(2002)
Expert Opinion on Investigational Drugs
, vol.11
, Issue.12
, pp. 1775-1787
-
-
Lehman, N.L.1
-
5
-
-
33645466805
-
Ashkenazi founder BRCA1/BRCA2 mutations in Slovak hereditary breast and/or ovarian cancer families
-
CIERNIKOVA S, TOMKA M, KOVAC M, STEVURKOVA V, ZAJAC V. Ashkenazi founder BRCA1/BRCA2 mutations in Slovak hereditary breast and/or ovarian cancer families. Neoplasma 2006; 53: 97-102.
-
(2006)
Neoplasma
, vol.53
, pp. 97-102
-
-
Ciernikova, S.1
Tomka, M.2
Kovac, M.3
Stevurkova, V.4
Zajac, V.5
-
6
-
-
33745876823
-
TP MT, UGT1A1 and DPYD: Genotyping to ensure safer cancer therapy?
-
Aug
-
MAITLAND ML, VASISHT K, RATAIN MJ. TP MT, UGT1A1 and DPYD: genotyping to ensure safer cancer therapy? Trends Pharmacol Sci 2006 Aug; 27: 432-437.
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 432-437
-
-
Maitland, M.L.1
Vasisht, K.2
Ratain, M.J.3
-
7
-
-
27144505860
-
Tailored therapy of colorectal cancer: Results, challenges and future directions
-
GSAPARINI G, LONGO R, TORINO F, BARONE C, TOFFOLI G. Tailored therapy of colorectal cancer: results, challenges and future directions. Cancer J 2005; 11: 175-188. (Pubitemid 44698804)
-
(2005)
Cancer Journal
, vol.11
, Issue.3
, pp. 175-188
-
-
Gasparini, G.1
Longo, R.2
Torino, F.3
Barone, C.4
Toffoli, G.5
-
8
-
-
32944456234
-
Pharmacogenetics and pediatric cancer
-
Jul-Aug
-
BOMGAARS L, McLEOD HL. Pharmacogenetics and pediatric cancer. Cancer J 2005 Jul-Aug; 11: 314-323.
-
(2005)
Cancer J
, vol.11
, pp. 314-323
-
-
Bomgaars, L.1
McLeod, H.L.2
-
9
-
-
33644840600
-
Acute lymphoblastic leukaemia: A model for the pharmacogenomics of cancer therapy
-
CHEOK MH, EVANS WE. Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy. Nature Rev Cancer 2006; 6: 117-127.
-
(2006)
Nature Rev Cancer
, vol.6
, pp. 117-127
-
-
Cheok, M.H.1
Evans, W.E.2
-
10
-
-
23644448453
-
Personalised medicine for cancer: From drug development into clinical practice
-
DOI 10.1517/14656566.6.9.1463
-
JAIN KK. Personalised medicine for cancer: from drug development into clinical practice. Expert Opin Pharmacother 2005; 6: 1463-1476. (Pubitemid 41131687)
-
(2005)
Expert Opinion on Pharmacotherapy
, vol.6
, Issue.9
, pp. 1463-1476
-
-
Jain, K.K.1
-
11
-
-
0042914711
-
Homocystein, pharmacogenetics and neurotoxicity in children with leukemia
-
KISHI S, GRIENER J, CHENG CH et al. Homocystein, pharmacogenetics and neurotoxicity in children with leukemia. J Clin Oncol 2003; 21: 3084-3089.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3084-3089
-
-
Kishi, S.1
Griener, J.2
Cheng, C.H.3
-
12
-
-
33746305081
-
Genetic polymorphism at GSTM1 and GSTT1 gene loci and susceptibility to oral cancer
-
SHARMA A, MISHRA A, DAS BC, SARDANA S, SHARMA JK. Genetic polymorphism at GSTM1 and GSTT1 gene loci and susceptibility to oral cancer. Neoplasma 2006; 53: 309-315. (Pubitemid 44105936)
-
(2006)
Neoplasma
, vol.53
, Issue.4
, pp. 309-315
-
-
Sharma, A.1
Mishra, A.2
Das, B.C.3
Sardana, S.4
Sharma, J.K.5
-
13
-
-
13844316592
-
Cancer pharmacogenomics: Powerful tools in cancer chemotherapy and drug development
-
LEE W, LOCKHART AC, KIM RB, ROTHENBERG ML. Cancer pharmacogenomics: Powerful tools in cancer chemotherapy and drug development. Oncologist 2005; 10: 104-111.
-
(2005)
Oncologist
, vol.10
, pp. 104-111
-
-
Lee, W.1
Lockhart, A.C.2
Kim, R.B.3
Rothenberg, M.L.4
-
14
-
-
0842286886
-
Cancer pharmacogenetics
-
MARSH S, McLEOD HL. Cancer pharmacogenetics. Br J Cancer 2004, 90: 8-11.
-
(2004)
Br J Cancer
, vol.90
, pp. 8-11
-
-
Marsh, S.1
McLeod, H.L.2
-
15
-
-
0032231751
-
Pharmacogenetics of cancer therapy: Getting personal
-
KRYNETSKI EY, EVANS WE. Pharmacogenetics of cancer therapy: getting personal. Am J Hum Genet 1998; 63: 11-16.
-
(1998)
Am J Hum Genet
, vol.63
, pp. 11-16
-
-
Krynetski, E.Y.1
Evans, W.E.2
-
16
-
-
4344604014
-
Pharmacogenomics in cancer therapy: Is host genome variability important?
-
PETROS WP, EVANS WE. Pharmacogenomics in cancer therapy: is host genome variability important ? Trends Pharmacol Sci 2004; 25: 457-464.
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 457-464
-
-
Petros, W.P.1
Evans, W.E.2
-
18
-
-
84906163584
-
Interactions of antimycotics in dermatology
-
WAWRUCH M, BOŽEKOVÁ L, MAGULOVÁ L, DOSTÁLOVÁ D, SLÁDEKOVÁ J et al. Interactions of antimycotics in dermatology. Čes-slov Derm 2004; 79: 7-12.
-
(2004)
Čes-slov Derm
, vol.79
, pp. 7-12
-
-
Wawruch, M.1
Božeková, L.2
Magulová, L.3
Dostálová, D.4
Sládeková, J.5
-
19
-
-
4243105910
-
Polypharmacotherapy in clinical gerontology
-
in Czech
-
WEBER P, KRIŠKA M, MELUZÍNOVÁ H, DÍTĚTOVÁ K, WAWRUCH M. Polypharmacotherapy in clinical gerontology. Čas Lék Čes 2004; 143: 547-551 (in Czech).
-
(2004)
Čas Lék Čes
, vol.143
, pp. 547-551
-
-
Weber, P.1
Kriška, M.2
Meluzínová, H.3
Dítětová, K.4
Wawruch, M.5
-
20
-
-
33751120138
-
Perception of potentially inappropriate medication in elderly patients by Slovak physicians
-
in press
-
WAWRUCH M, ZIKAVSKA M, WSOLOVA L, JEZOVA D, FIALOVA D et al. Perception of potentially inappropriate medication in elderly patients by Slovak physicians. Pharmacoepidemiol Drug Saf 2006; 15: (in press).
-
(2006)
Pharmacoepidemiol Drug Saf
, vol.15
-
-
Wawruch, M.1
Zikavska, M.2
Wsolova, L.3
Jezova, D.4
Fialova, D.5
-
22
-
-
0344197480
-
Cancer pharmacogenetics: Polymorphisms, pathways and beyond
-
ULRICH CM, ROBIEN K, McLEOD HL. Cancer pharmacogenetics: polymorphisms, pathways and beyond. Nat Rev Cancer 2003; 3: 912-920.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 912-920
-
-
Ulrich, C.M.1
Robien, K.2
McLeod, H.L.3
-
23
-
-
0037446134
-
Targeted therapy and pharmacogenetic programs
-
IQBAL S, LENZ HJ. Targeted therapy and pharmacogenetic programs. Cancer 2003; 97: 2076-2078.
-
(2003)
Cancer
, vol.97
, pp. 2076-2078
-
-
Iqbal, S.1
Lenz, H.J.2
-
25
-
-
21344453004
-
Pharmacogenetics for individualized cancer chemotherapy
-
EFFERTH T, VOLM M. Pharmacogenetics for individualized cancer chemotherapy. Pharmacol Ther 2005; 107: 155-176.
-
(2005)
Pharmacol Ther
, vol.107
, pp. 155-176
-
-
Efferth, T.1
Volm, M.2
-
26
-
-
18744392678
-
Pharmacogenomics of chemotherapeutic agents in cancer treatment
-
Licinio J, Ma-Li Wong. Weinheim: Wiley-VCH Verlag
-
INNOCENTI I, IYER L, RATAIN MJ. Pharmacogenomics of chemotherapeutic agents in cancer treatment. In: Licinio J, Ma-Li Wong. Pharmacogenomics. The Search for Individualized Therapies. Weinheim: Wiley-VCH Verlag 2002a: 283-303.
-
(2002)
Pharmacogenomics. The Search for Individualized Therapies
, pp. 283-303
-
-
Innocenti, I.1
Iyer, L.2
Ratain, M.J.3
-
27
-
-
33645081745
-
Human methylenetetrahydrofolate reductase pharmacogenomics: Gene resequencing and functional genomics
-
Apr
-
MARTIN YN, SALAVAGGIONE OE, ECKLOFF BW, WIEBEN ED, SCHAID DJ, WEINSHILBOUM RM. Human methylenetetrahydrofolate reductase pharmacogenomics: gene resequencing and functional genomics. Pharmacogenet Genomics 2006 Apr;16: 265-277.
-
(2006)
Pharmacogenet Genomics
, vol.16
, pp. 265-277
-
-
Martin, Y.N.1
Salavaggione, O.E.2
Eckloff, B.W.3
Wieben, E.D.4
Schaid, D.J.5
Weinshilboum, R.M.6
-
29
-
-
0041303650
-
Clinical implications of dihydropyrimidine dehydrogenase (DPD) activity in 5-FU-based chemotherapy: Mutations in the DPD gene, and DPD inhibitors fluoropyrimidines
-
OMURA K. Clinical implications of dihydropyrimidine dehydrogenase (DPD) activity in 5-FU-based chemotherapy: mutations in the DPD gene, and DPD inhibitors fluoropyrimidines. Int J Clin Oncol 2003; 8: 132-138.
-
(2003)
Int J Clin Oncol
, vol.8
, pp. 132-138
-
-
Omura, K.1
-
30
-
-
0035750549
-
Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy
-
PULLARKAT ST, STOEHLMACHER J, GHADERI V, XIONG IQ, INQLES SA et al. Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy. Pharmacogenomics J 2001;1: 65-70.
-
(2001)
Pharmacogenomics J
, vol.1
, pp. 65-70
-
-
Pullarkat, S.T.1
Stoehlmacher, J.2
Ghaderi, V.3
Xiong, I.Q.4
Inqles, S.A.5
-
31
-
-
0042196122
-
Irinotecan pathway genotype analysis to predict pharmacokinetics
-
MATHIJSSEN RH, MARSH S, KARLSSON MO, XIE R, BAKER SD et al. Irinotecan pathway genotype analysis to predict pharmacokinetics. Clin Cancer Res 2003; 9: 3246-3253.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3246-3253
-
-
Mathijssen, R.H.1
Marsh, S.2
Karlsson, M.O.3
Xie, R.4
Baker, S.D.5
-
32
-
-
33646564372
-
Interpreting disparate responses to cancer therapy: The role of human population genetics
-
[32) MAITLAND ML, DIRIENZO A, RATAIN MJ. Interpreting disparate responses to cancer therapy: the role of human population genetics. J Clin Oncol 2006; 24: 2151-2157.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2151-2157
-
-
Maitland, M.L.1
Dirienzo, A.2
Ratain, M.J.3
-
33
-
-
0033486029
-
Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus
-
RELLING MV, HANCOCK ML, RIVERA GK, SANDLUND JT, RIBEIRO R et al. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus. J Natl Cancer Inst 1999a; 91: 2001-2008.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 2001-2008
-
-
Relling, M.V.1
Hancock, M.L.2
Rivera, G.K.3
Sandlund, J.T.4
Ribeiro, R.5
-
34
-
-
0033519986
-
High incidence of secondary brain tumours after radiotherapy and antimetabolites
-
RELLING MV, RUBNITZ JE, RIVERA GK, BOYETT JM, HANCOCK ML et al. High incidence of secondary brain tumours after radiotherapy and antimetabolites. Lancet 1999b; 354: 34-39.
-
(1999)
Lancet
, vol.354
, pp. 34-39
-
-
Relling, M.V.1
Rubnitz, J.E.2
Rivera, G.K.3
Boyett, J.M.4
Hancock, M.L.5
-
36
-
-
30444451921
-
Thiopurine methyltransferase in acute lymphoblastic leukemia [4]
-
DOI 10.1182/blood-2005-08-3379
-
RELLING MV, PUI CH, CHENG CH. Thiopurine methyl-transferase in acute lymphoblastic leukemia. Blood 2006; 107: 843-844. (Pubitemid 43076417)
-
(2006)
Blood
, vol.107
, Issue.2
, pp. 843-844
-
-
Relling, M.V.1
Pui, C.-H.2
Cheng, C.3
Evans, W.E.4
-
37
-
-
0028861745
-
A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase
-
KRYNETSKI EY, SCHUETZ JD, GALPIN AJ et al. A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase. Proc Natl Acad Sci 1995; 92: 949-953.
-
(1995)
Proc Natl Acad Sci
, vol.92
, pp. 949-953
-
-
Krynetski, E.Y.1
Schuetz, J.D.2
Galpin, A.J.3
-
38
-
-
0036660410
-
Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia
-
DOI 10.1182/blood.V100.1.67
-
DAVIES SM, BHATIA S, ROSS JA et al. Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia. Blood 2002; 100: 67-71. (Pubitemid 35177430)
-
(2002)
Blood
, vol.100
, Issue.1
, pp. 67-71
-
-
Davies, S.M.1
Bhatia, S.2
Ross, J.A.3
Kiffmeyer, W.R.4
Gaynon, P.S.5
Radloff, G.A.6
Robison, L.L.7
Perentesis, J.P.8
-
39
-
-
0033569516
-
Pharmacogenomics: Translating functional genomics into rational therapeutics
-
286
-
EVANS WE, RELLING MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286, 1999; 5439: 487-491.
-
(1999)
Science
, vol.5439
, pp. 487-491
-
-
Evans, W.E.1
Relling, M.V.2
-
40
-
-
33750581390
-
Three novel thiopurine S-methyltransferase allelic variants (TPMT*20, *21, *22) - Association with decreased enzyme function
-
Sep
-
SCHAEFFELER E, EICHELBAUM M, REINISCH W, ZANGER UM, SCHWAB M. Three novel thiopurine S-methyltransferase allelic variants (TPMT*20, *21, *22) - association with decreased enzyme function. Hum Mutat 2006 Sep; 27(9): 976.
-
(2006)
Hum Mutat
, vol.27
, Issue.9
, pp. 976
-
-
Schaeffeler, E.1
Eichelbaum, M.2
Reinisch, W.3
Zanger, U.M.4
Schwab, M.5
-
41
-
-
0033828949
-
Genetic polymorphism of thiopurine S-methyltransferase: Molecular mechanisms and clinical importance
-
KRYNETSKI EY, EVANS WE. Genetic polymorphism of thiopurine S-methyltransferase: molecular mechanisms and clinical importance. Pharmacology 2000; 61: 136-146.
-
(2000)
Pharmacology
, vol.61
, pp. 136-146
-
-
Krynetski, E.Y.1
Evans, W.E.2
-
42
-
-
0242312707
-
Drug methylation in cancer therapy: Lessons from the TPMT polymorphism
-
22
-
KRYNETSKI EY, EVANS WE.Drug methylation in cancer therapy: lessons from the TPMT polymorphism. Oncogene 22, 2003; 47: 7403-7413.
-
(2003)
Oncogene
, vol.47
, pp. 7403-7413
-
-
Krynetski, E.Y.1
Evans, W.E.2
-
43
-
-
0142240380
-
Preventing toxicity with a gene test
-
MARSHALL E. Preventing toxicity with a gene test. Science 2003; 302(5645): 588-590
-
(2003)
Science
, vol.302
, Issue.5645
, pp. 588-590
-
-
Marshall, E.1
-
44
-
-
0034034158
-
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood lymphoblastic leukemia
-
McLEOD HL, KRYNETSKI EY, RELLING MV, EVANS WE. Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood lymphoblastic leukemia. Leukemia 2000; 14: 567-572.
-
(2000)
Leukemia
, vol.14
, pp. 567-572
-
-
McLeod, H.L.1
Krynetski, E.Y.2
Relling, M.V.3
Evans, W.E.4
-
45
-
-
0036009619
-
The thiopurine S-methyltransferase gene locus - Implications for clinical pharmacogenomics
-
McLEOD HL, SIVA C. The thiopurine S-methyltransferase gene locus - implications for clinical pharmacogenomics. Pharmacogenomics 2002; 3: 89-98.
-
(2002)
Pharmacogenomics
, vol.3
, pp. 89-98
-
-
McLeod, H.L.1
Siva, C.2
-
46
-
-
0036066914
-
Thiopurine methyltransferase polymorphism in a multiracial Asian population and children with acute lymphoblastic leukemia
-
KHAM SK, TAN PL, TAY AH, HENG CK, YEOH AF et al. Thiopurine methyltransferase polymorphism in a multiracial Asian population and children with acute lymphoblastic leukemia. J Pediatr Hematol Oncol 2002; 24: 353-359.
-
(2002)
J Pediatr Hematol Oncol
, vol.24
, pp. 353-359
-
-
Kham, S.K.1
Tan, P.L.2
Tay, A.H.3
Heng, C.K.4
Yeoh, A.F.5
-
47
-
-
24944544420
-
Drug-metabolizing enzyme polymorphisms predict clinical outcome in a node-positive breast cancer cohort
-
Aug
-
DeMICHELE A, APLENC R, BOTBYL J, COLLIGAN T, WRAY L, KLEIN-CABRAL M, FOULKES A, GIMOTTY P, GLICK J, WEBER B, STADTMAUER E, REBBECK TR. Drug-metabolizing enzyme polymorphisms predict clinical outcome in a node-positive breast cancer cohort. J Clin Oncol 2005 Aug 20; 23: 5552-5559.
-
(2005)
J Clin Oncol
, vol.20
, Issue.23
, pp. 5552-5559
-
-
DeMichele, A.1
Aplenc, R.2
Botbyl, J.3
Colligan, T.4
Wray, L.5
Klein-Cabral, M.6
Foulkes, A.7
Gimotty, P.8
Glick, J.9
Weber, B.10
Stadtmauer, E.11
Rebbeck, T.R.12
-
48
-
-
0037134707
-
Association between glutathione s-transferase P1, T1, and M1 genetic polymorphism and surival of patients with metastatic colorectal caneer
-
Jun
-
STOEHLMACHER J, PARK DJ, ZHANG W et al. Association between glutathione s-transferase P1, T1, and M1 genetic polymorphism and surival of patients with metastatic colorectal caneer. J Natl Cancer Inst 2002 Jun; 94(12): 936-942.
-
(2002)
J Natl Cancer Inst
, vol.94
, Issue.12
, pp. 936-942
-
-
Stoehlmacher, J.1
Park, D.J.2
Zhang, W.3
-
49
-
-
0035281735
-
Glutathione S-transferase polymorphisms and outcome of chemotherapy in childhood acute myeloid leukemia
-
DAVIES SM, ROBISON LL, BUCKLEY JD et al. Glutathion-S-transferase polymorphisms and outcome of chemotherapy in childhood acute myeloid leukemia. J Clin Oncol 2001; 19: 1279-1287. (Pubitemid 32202531)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.5
, pp. 1279-1287
-
-
Davies, S.M.1
Robison, L.L.2
Buckley, J.D.3
Tjoa, T.4
Woods, W.G.5
Radloff, G.A.6
Ross, J.A.7
Perentesis, J.P.8
-
50
-
-
33745008604
-
Pathogenesis of cardiotoxicity induced by anthracyclines
-
ELLIOTT P. Pathogenesis of cardiotoxicity induced by anthracyclines. Semin Oncol 2006; 33, Suppl 8: 2-7.
-
(2006)
Semin Oncol
, vol.33
, Issue.SUPPL. 8
, pp. 2-7
-
-
Elliott, P.1
-
51
-
-
0034164652
-
Late effects of anthracycline therapy in childhood on signal-averaged ECG parameters
-
Apr
-
MLADOSIEVIČOVÁ B, FOLTINOVÁ A, PETRÁŠ OVÁ H, HULÍN I. Late effects of anthracycline therapy in childhood on signal-averaged ECG parameters. Int J Mol Med 2000 Apr; 5: 411-414.
-
(2000)
Int J Mol Med
, vol.5
, pp. 411-414
-
-
Mladosievičová, B.1
Foltinová, A.2
Petráš ová, H.3
Hulín, I.4
-
52
-
-
0032965572
-
Role of iron in anthracycline cardiotoxicity: New tunes for an old song?
-
MINOTTI G, CAIRO G, MONTI E. Role of iron in anthracycline cardiotoxicity: new tunes for an old song? FASEB J 1999; 13: 199-212.
-
(1999)
FASEB J
, vol.13
, pp. 199-212
-
-
Minotti, G.1
Cairo, G.2
Monti, E.3
-
53
-
-
34548330602
-
Polymorphisms in candidate genes in patients with congestive heart failure (CHF) after childhood cancer: A Report from the Childhood Cancer Survivor Study (CCSS)
-
ASCO Annual Meeting Proceedings Part I.
-
APLENC R, BLANCO J, LEISENRING W et al. Polymorphisms in candidate genes in patients with congestive heart failure (CHF) after childhood cancer: A Report from the Childhood Cancer Survivor Study (CCSS). J Clin Oncol 2006; ASCO Annual Meeting Proceedings Part I., Vol 24 (June 20 Suppl): 9004.
-
(2006)
J Clin Oncol
, vol.24
, Issue.JUNE 20 SUPPL.
, pp. 9004
-
-
Aplenc, R.1
Blanco, J.2
Leisenring, W.3
-
54
-
-
0018894446
-
Degradation of pyrimidines and pyrimidine analogs - Pathways and mutual influences
-
WASTERNACK C. Degradation of pyrimidines and pyrimidine analogs - pathways and mutual influences. Pharmacol Ther 1980; 8: 629-652.
-
(1980)
Pharmacol Ther
, vol.8
, pp. 629-652
-
-
Wasternack, C.1
-
55
-
-
0023187085
-
Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile
-
HEGGIE GD, SOMMADOSSI JP, CROSS DS, HUSTLER WJ, DIASIO RB. Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile. Cancer Res 1987; 47: 2203-2206. (Pubitemid 17074634)
-
(1987)
Cancer Research
, vol.47
, Issue.8
, pp. 2203-2206
-
-
Heggie, G.D.1
Sommadossi, J.-P.2
Cross, D.S.3
-
56
-
-
84906200654
-
Final results of a prospective multicenter study on the prevalence and genotype/phenotype correlation of the dihydropyrimidine dehydrogenase (DPD) gene exon-14 skipping mutation in patients treated with 5-fluorouracil (5-FU) chemotherapy
-
ASCO Annual Meeting Proceedings Part I., 2006
-
RAIDA M, FRIEDRICH A, BORRIS M, NIEDERWIESER D, BEHNKE D, KLICHE KO et al. Final results of a prospective multicenter study on the prevalence and genotype/phenotype correlation of the dihydropyrimidine dehydrogenase (DPD) gene exon-14 skipping mutation in patients treated with 5-fluorouracil (5-FU) chemotherapy. J Clin Oncol 2006, ASCO Annual Meeting Proceedings Part I., Vol 24 (18S) (June 20 Supplement), 2006: 3076
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S JUNE 20 SUPPL.
, pp. 3076
-
-
Raida, M.1
Friedrich, A.2
Borris, M.3
Niederwieser, D.4
Behnke, D.5
Kliche, K.O.6
-
57
-
-
68949087331
-
Molecular basis of altered uracil catabolism in individuals with 5-FU toxicity and normal DPD enzyme activity
-
ASCO Annual Meeting Proceedings Part I., 2006
-
REED HA, EZZELDIN HH, MATTISON LK, DIASI RB. Molecular basis of altered uracil catabolism in individuals with 5-FU toxicity and normal DPD enzyme activity. J Clin Oncol 2006, ASCO Annual Meeting Proceedings Part I., Vol 24 (18S) (June 20 Supplement), 2006: 3070.
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S JUNE 20 SUPPL.
, pp. 3070
-
-
Reed, H.A.1
Ezzeldin, H.H.2
Mattison, L.K.3
Diasi, R.B.4
-
58
-
-
33645120407
-
Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer
-
NAGAR S, REMMEL RP. Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer. Oncogene 2006; 25: 1659-1672.
-
(2006)
Oncogene
, vol.25
, pp. 1659-1672
-
-
Nagar, S.1
Remmel, R.P.2
-
59
-
-
0030580064
-
Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxy-camptothecin (SN-38), by human liver carboxylesterase
-
RIVORY L P, BOWLES M R, ROBERT J, POND S M. Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxy-camptothecin (SN-38), by human liver carboxylesterase. Biochem. Pharmacol 1996; 52: 1103-1111.
-
(1996)
Biochem. Pharmacol
, vol.52
, pp. 1103-1111
-
-
Rivory, L.P.1
Bowles, M.R.2
Robert, J.3
Pond, S.M.4
-
60
-
-
0028867826
-
The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
-
BOSMA PJ, CHOWDHURY JR, BAKKER C, GANTLA S, DE BOER A et al. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 1995; 333: 1171-1175.
-
(1995)
N Engl J Med
, vol.333
, pp. 1171-1175
-
-
Bosma, P.J.1
Chowdhury, J.R.2
Bakker, C.3
Gantla, S.4
De Boer, A.5
-
61
-
-
0032493441
-
Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: A balanced polymorphism for regulation of bilirubin metabolism?
-
BEUTLER E, GELBART T, DEMINA A. Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism? Proc Natl Acad Sci USA 1998; 95: 8170-8174.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8170-8174
-
-
Beutler, E.1
Gelbart, T.2
Demina, A.3
-
62
-
-
12244271026
-
Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups
-
INNOCENTI F, GRIMSLEY D, DAS S, RAMIREZ J, CHENG C et al. Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups. Pharmacogenetics 2002b; 12: 725-733.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 725-733
-
-
Innocenti, F.1
Grimsley, D.2
Das, S.3
Ramirez, J.4
Cheng, C.5
-
63
-
-
33750176033
-
Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer (FOCUS)
-
ASCO Annual Meeting Proceedings Part I., 2006
-
SEYMOUR MT, BRAUN MS, RICHMAN, SD et al. Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer (FOCUS). J Clin Oncol 2006, ASCO Annual Meeting Proceedings Part I., Vol 24 (18S) (June 20 Supplement), 2006: 2022.
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S JUNE 20 SUPPL.
, pp. 2022
-
-
Seymour, M.T.1
Braun, M.S.2
Richman, S.D.3
-
64
-
-
84906171282
-
TYMS polymorphism analysis prediction of bolus 5-fluorouracil toxicity
-
ASCO Annual Meeting Proceedings Part I., 2006
-
GUSELLA M, BOLZONELLA C, BERTOLASO L et al. TYMS polymorphism analysis prediction of bolus 5-fluorouracil toxicity. J Clin Oncol 2006; ASCO Annual Meeting Proceedings Part I., Vol 24 (18S) (June 20 Suppl), 2006: 13022.
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S JUNE 20 SUPPL.
, pp. 13022
-
-
Gusella, M.1
Bolzonella, C.2
Bertolaso, L.3
-
65
-
-
0036928840
-
Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate
-
CHIUSOLO P, REDDICONTO G, CASORELLI I, LAURENTI L, SORA F et al. Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate. Ann Oncol 2002; 13: 1915-1918.
-
(2002)
Ann Oncol
, vol.13
, pp. 1915-1918
-
-
Chiusolo, P.1
Reddiconto, G.2
Casorelli, I.3
Laurenti, L.4
Sora, F.5
-
66
-
-
0027842835
-
Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals
-
BORST P, SCHINKEL AH, SMIT JJ, WAGENAAR E, VAN DEEMTER L et al. Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals. Pharmacol Ther 1993; 60: 289-299.
-
(1993)
Pharmacol Ther
, vol.60
, pp. 289-299
-
-
Borst, P.1
Schinkel, A.H.2
Smit, J.J.3
Wagenaar, E.4
Van Deemter, L.5
-
67
-
-
0031158805
-
The physiological function of drug-transporting P-glycoproteins
-
SCHINKEL AH. The physiological function of drug-transporting P-glycoproteins. Semin Cancer Biol 1997; 8: 161-170.
-
(1997)
Semin Cancer Biol
, vol.8
, pp. 161-170
-
-
Schinkel, A.H.1
-
68
-
-
0037362355
-
ATP binding cassette transporters and drug resistance in breast cancer
-
DOI 10.1677/erc.0.0100043
-
LEONESSA F, CLARKE R. ATP binding cassette transporters and drug resistance in breast cancer. Endocr Relat Cancer 2003; 10: 43-73. (Pubitemid 36457239)
-
(2003)
Endocrine-Related Cancer
, vol.10
, Issue.1
, pp. 43-73
-
-
Leonessa, F.1
Clarke, R.2
-
69
-
-
4644359707
-
Targeting the multidrug resistance-1 transporter in AML: Molecular regulation and therapeutic strategies
-
MAHADEVAN D, LIST AF. Targeting the multidrug resistance-1 transporter in AML: molecular regulation and therapeutic strategies. Blood 2004; 104: 1940-1951.
-
(2004)
Blood
, vol.104
, pp. 1940-1951
-
-
Mahadevan, D.1
List, A.F.2
-
70
-
-
33644860579
-
An update on overcoming MDR1-mediated multidrug resistance in cancer chemotherapy
-
TAKARA K, SAKAEDA T, OKUMURA K. An update on overcoming MDR1-mediated multidrug resistance in cancer chemotherapy. Curr Pharm Des 2006; 12: 273-286.
-
(2006)
Curr Pharm des
, vol.12
, pp. 273-286
-
-
Takara, K.1
Sakaeda, T.2
Okumura, K.3
-
71
-
-
0037110469
-
Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia
-
LAVERDIERE C, CHIASSON S, COSTEA I, MOGHRABI A, KRAJINOVIC M. Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia. Blood 2002; 100: 3832-3834.
-
(2002)
Blood
, vol.100
, pp. 3832-3834
-
-
Laverdiere, C.1
Chiasson, S.2
Costea, I.3
Moghrabi, A.4
Krajinovic, M.5
-
72
-
-
0038779673
-
Reduced folate carrier: Biochemistry and molecular biology of the normal and methotrexate-resistant cell
-
BOSSON G. Reduced folate carrier: biochemistry and molecular biology of the normal and methotrexate-resistant cell. Br J Biomed Sci 2003; 60: 117-129.
-
(2003)
Br J Biomed Sci
, vol.60
, pp. 117-129
-
-
Bosson, G.1
-
73
-
-
0034666338
-
Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: A report from the Children's Cancer Group
-
MATTANO LA JR, SATHER HN, TRIGG ME et al. Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: A report from the Children's Cancer Group. J Clin Oncol 2000; 18: 3262-3272.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3262-3272
-
-
Mattano Jr., L.A.1
Sather, H.N.2
Trigg, M.E.3
-
74
-
-
68949092967
-
Possibility of late consequences of anticancer treatment in childhood
-
ISBN 80-8095-004-0 (in press)
-
MLADOSIEVICOVA B, KAISEROVA E, FOLTINOVA A. Possibility of late consequences of anticancer treatment in childhood. SAP 2007, ISBN 80-8095-004-0 (in press).
-
(2007)
SAP
-
-
Mladosievicova, B.1
Kaiserova, E.2
Foltinova, A.3
-
75
-
-
33747115419
-
The association between common vitamin D receptor gene variations and osteoporosis: A participant-level meta-analysis
-
UITTERLINDEN AG, RALSTON SH, BRANDI ML et al. The association between common vitamin D receptor gene variations and osteoporosis: a participant-level metaanalysis. Ann Intern Med 2006 Aug 15; 145 (4): 255-264. (Pubitemid 46768609)
-
(2006)
Annals of Internal Medicine
, vol.145
, Issue.4
, pp. 255-264
-
-
Uitterlinden, A.G.1
Ralston, S.H.2
Brandi, M.L.3
Carey, A.H.4
Grinberg, D.5
Langdahl, B.L.6
Lips, P.7
Lorenc, R.8
Obermayer-Pietsxch, B.9
Reeve, J.10
Reid, D.M.11
Amedei, A.12
Bassiti, A.13
Bustamante, M.14
Husted, L.B.15
Diez-Perez, A.16
Dobnig, H.17
Dunning, A.M.18
Enjuanes, A.19
Fahrleitner-Pammer, A.20
Fang, Y.21
Karczmarewicz, E.22
Kruk, M.23
Van Leeuwen, J.P.T.M.24
Mavilia, C.25
Van Meurs, J.B.J.26
Mangion, J.27
McGuigan, F.E.A.28
Pols, H.A.P.29
Renner, W.30
Rivadeneira, F.31
Van Schoor, N.M.32
Scollen, S.33
Sherlock, R.E.34
Ioannidis, J.P.A.35
Parsons, C.36
Bear, S.37
Farmer, R.38
Lukaszkiewicz, J.39
Bilinski, P.40
Czerwinski, E.41
Lewinski, A.42
Marcinowska-Suchowierska, E.43
Milewicz, A.44
Spaczynski, M.45
Jaworski, M.46
Nuti, R.47
Grazio, S.48
Miazgowski, T.49
Boonen, R.50
Masaryk, P.51
Stepan, J.J.52
Lopes Vaz, A.53
Cannata, J.54
Weber, K.55
Benevolenskaya, L.I.56
Todd, C.57
Khaw, K.-T.58
Da Silva, J.59
Bhalla, A.60
Poor, G.61
Bruges Armas, J.62
Lyritis, G.63
O'Neill, T.W.64
Lunt, M.65
Compston, J.66
Cooper, C.67
Duncan, E.68
Keen, R.69
McLellan, A.70
Wass, J.71
Dekema, E.72
Van Essen, H.73
Pluijm, S.74
Bravenboer, N.75
Hofman, A.76
Van Duijn, C.M.77
De Jong, P.J.78
Breteler, M.M.79
Stricker, B.H.80
Witteman, J.C.81
more..
-
76
-
-
5444266905
-
Pharmacogenetic risk factors for osteonecrosis of the hip among children with leukemia
-
RELLING MV, YANG W, DAS S et al. Pharmacogenetic risk factors for osteonecrosis of the hip among children with leukemia. J Clin Oncol 2004; 22 (11): 3930-3936.
-
(2004)
J Clin Oncol
, vol.22
, Issue.11
, pp. 3930-3936
-
-
Relling, M.V.1
Yang, W.2
Das, S.3
-
77
-
-
0034048729
-
Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
-
Apr
-
SALONGA D, DANENBERG KD, JOHNSON M et al. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin Cancer Res 2000 Apr; 6(4): 1322-1327.
-
(2000)
Clin Cancer Res
, vol.6
, Issue.4
, pp. 1322-1327
-
-
Salonga, D.1
Danenberg, K.D.2
Johnson, M.3
-
78
-
-
85047692068
-
Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics
-
KAGER L, CHEOK M, YANG W et al. Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics. J Clin Invest 2005; 115: 110-117.
-
(2005)
J Clin Invest
, vol.115
, pp. 110-117
-
-
Kager, L.1
Cheok, M.2
Yang, W.3
-
79
-
-
0033837696
-
Predicting response to chronic antihypertensive treatment with fosinopril: The role of angiotensin-converting enzyme gene polymorphism
-
STAVROULAKIS GA, MAKRIS TK, KRESPI PG et al. Predicting response to chronic antihypertensive treatment with fosinopril: the role of angiotensin-converting enzyme gene polymorphism. Cardiovasc Drug Ther 2000; 14: 427-432.
-
(2000)
Cardiovasc Drug Ther
, vol.14
, pp. 427-432
-
-
Stavroulakis, G.A.1
Makris, T.K.2
Krespi, P.G.3
-
80
-
-
0035052741
-
Effect of polymorphisms of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma
-
ISRAEL E, DRAZEN JM, LIGGETT SB et al. Effect of polymorphisms of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma. Int Arch Allergy Immunol 2001; 124: 183-186.
-
(2001)
Int Arch Allergy Immunol
, vol.124
, pp. 183-186
-
-
Israel, E.1
Drazen, J.M.2
Liggett, S.B.3
-
81
-
-
0034612110
-
Pharmacogenetic prediction of clozapine response
-
ARRANZ MJ, MUNRO J, BIRKETT J et al. Pharmacogenetic prediction of clozapine response. Lancet 2000; 355: 1615-1616.
-
(2000)
Lancet
, vol.355
, pp. 1615-1616
-
-
Arranz, M.J.1
Munro, J.2
Birkett, J.3
-
82
-
-
84906102254
-
Problems of pain medicine in pregradual medical and nursing teaching
-
in Slovak
-
BERNADIČ M., KULICHOVÁ M.: Problems of pain medicine in pregradual medical and nursing teaching. Reumatológia 2002; 16: 199-200 (in Slovak).
-
(2002)
Reumatológia
, vol.16
, pp. 199-200
-
-
Bernadič, M.1
Kulichová, M.2
-
83
-
-
0037187926
-
Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease
-
HERRINGTON DM, HOWARD TD, HAWKINS GA et al. Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease. N Engl J Med 2002; 346: 967-974.
-
(2002)
N Engl J Med
, vol.346
, pp. 967-974
-
-
Herrington, D.M.1
Howard, T.D.2
Hawkins, G.A.3
-
84
-
-
0037421590
-
Pharmacogenomics - Drug disposition, drug targets, and side effects
-
DOI 10.1056/NEJMra020526
-
EVANS WE, McLEOD HL. Pharmacogenomics-drug disposition, drug targets, and side effects. N Engl J Med 2003; 348:538-549. (Pubitemid 36159890)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.6
, pp. 538-549
-
-
Evans, W.E.1
McLeod, H.L.2
|