Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability

Neurochemistry International

Volumn 50, Issue 7-8, 2007, Pages 921-931

  Shi, Q ^a   Karuppagounder, S S ^a   Xu, H ^a   Pechman, D ^a   Chen, H ^a   Gibson, G E ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Ketoglutarate dehydrogenase complex; Micropunch; Oxidative stress; Rotarod; Submedial thalamic nucleus; Thiamine deficiency

Indexed keywords

DIHYDROLIPOAMIDE DEHYDROGENASE; DIHYDROLIPOYL SUCCINYLTRANSFERASE; MESSENGER RNA; OXOGLUTARATE DEHYDROGENASE; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; BRAIN REGION; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOCHEMISTRY; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MOTOR PERFORMANCE; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; ROTAROD TEST; THALAMUS NUCLEUS; THIAMINE DEFICIENCY; WESTERN BLOTTING;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; KETOGLUTARATE DEHYDROGENASE COMPLEX; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; PSYCHOMOTOR PERFORMANCE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; THIAMINE DEFICIENCY; TRANSCRIPTION, GENETIC;

MUS;

EID: 34250790605     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2007.03.010     Document Type: Article

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