-
1
-
-
33747122666
-
International AIDS Society - USA panel. Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society - USA panel
-
Hammer SM, Saag MS, Schechter M, et al. International AIDS Society - USA panel. Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society - USA panel. JAMA 2006; 296:827-843.
-
(2006)
JAMA
, vol.296
, pp. 827-843
-
-
Hammer, S.M.1
Saag, M.S.2
Schechter, M.3
-
2
-
-
1042300003
-
The prognostic importance of changes in CD4+ cell count and HIV-1 RNA level in women after initiating highly active antiretroviral therapy
-
Anastos K, Barron Y, Cohen MH, et al. The prognostic importance of changes in CD4+ cell count and HIV-1 RNA level in women after initiating highly active antiretroviral therapy. Ann Intern Med 2004; 140:256-264.
-
(2004)
Ann Intern Med
, vol.140
, pp. 256-264
-
-
Anastos, K.1
Barron, Y.2
Cohen, M.H.3
-
3
-
-
0041327811
-
Prognostic importance of initial response in HIV-1 infected patients starting potent antiretroviral therapy: Analysis of prospective studies
-
Chene G, Sterne JA, May M, et al. Prognostic importance of initial response in HIV-1 infected patients starting potent antiretroviral therapy: analysis of prospective studies. Lancet 2003; 362:679-686.
-
(2003)
Lancet
, vol.362
, pp. 679-686
-
-
Chene, G.1
Sterne, J.A.2
May, M.3
-
4
-
-
0037080037
-
-
Lundgren JD, Mocroft A, Gatell JM, et al. A clinically prognostic scoring system for patients receiving highly active antiretroviral therapy: results from the EuroSIDA study. J Infect Dis 2002; 185:178-187; Erratum appears in: J Infect Dis 2002; 186:145.
-
Lundgren JD, Mocroft A, Gatell JM, et al. A clinically prognostic scoring system for patients receiving highly active antiretroviral therapy: results from the EuroSIDA study. J Infect Dis 2002; 185:178-187; Erratum appears in: J Infect Dis 2002; 186:145.
-
-
-
-
5
-
-
0037165923
-
HIV long-term nonprogressors maintain brisk CD8 T cell responses to other viral antigens
-
Valdez H, Carlson NL, Post AB, et al. HIV long-term nonprogressors maintain brisk CD8 T cell responses to other viral antigens. AIDS 2002; 16:1113-1118.
-
(2002)
AIDS
, vol.16
, pp. 1113-1118
-
-
Valdez, H.1
Carlson, N.L.2
Post, A.B.3
-
6
-
-
0031957164
-
Simian immunodeficiency virus replicates to high levels in Sooty mangabeys without inducing disease
-
Rey-Cuille MA, Berthier JL, Bomsel-Demontoy MC, et al. Simian immunodeficiency virus replicates to high levels in Sooty mangabeys without inducing disease. J Virol 1998; 72:3872-3886.
-
(1998)
J Virol
, vol.72
, pp. 3872-3886
-
-
Rey-Cuille, M.A.1
Berthier, J.L.2
Bomsel-Demontoy, M.C.3
-
7
-
-
0035121414
-
Simian immunodeficiency virus replicates to high levels in naturally infected African green monkeys without inducing immunologic or neurologic disease
-
Broussard SR, Staprans SI, White R, et al. Simian immunodeficiency virus replicates to high levels in naturally infected African green monkeys without inducing immunologic or neurologic disease. J Virol 2001; 75:2262-2275.
-
(2001)
J Virol
, vol.75
, pp. 2262-2275
-
-
Broussard, S.R.1
Staprans, S.I.2
White, R.3
-
9
-
-
33749079234
-
-
Rodriguez B, Sethi AK, Cheruvu VK, et al. Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection. JAMA 2006; 296:1498-1506. A potentially paradigm-shifting cohort analysis that found that the level of HIV-1 RNA in plasma has only minimal predictive value for the rate of decline of the CD4+ T-lymphocyte count in an individual patient infected with HIV-1.
-
Rodriguez B, Sethi AK, Cheruvu VK, et al. Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection. JAMA 2006; 296:1498-1506. A potentially paradigm-shifting cohort analysis that found that the level of HIV-1 RNA in plasma has only minimal predictive value for the rate of decline of the CD4+ T-lymphocyte count in an individual patient infected with HIV-1.
-
-
-
-
10
-
-
0032955651
-
Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage
-
Giorgi JV, Hultin LE, McKeating JA, et al. Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. J Infect Dis 1999; 179:859-870.
-
(1999)
J Infect Dis
, vol.179
, pp. 859-870
-
-
Giorgi, J.V.1
Hultin, L.E.2
McKeating, J.A.3
-
11
-
-
0030913366
-
Quantitation of latent tissue reservoirs and total body load in HIV-1 infection
-
Chun T-W, Carruth L, Finzi D, et al. Quantitation of latent tissue reservoirs and total body load in HIV-1 infection. Nature 1997; 387:183-188.
-
(1997)
Nature
, vol.387
, pp. 183-188
-
-
Chun, T.-W.1
Carruth, L.2
Finzi, D.3
-
12
-
-
0027389013
-
Analysis of human immunodeficiency virus-infected tissues by amplification and in situ hybridization reveals latent and permissive infections at single-cell resolution
-
Embretson J, Zupancic M, Beneke J, et al. Analysis of human immunodeficiency virus-infected tissues by amplification and in situ hybridization reveals latent and permissive infections at single-cell resolution. Proc Natl Acad Sci U S A 1993; 90:357-361.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 357-361
-
-
Embretson, J.1
Zupancic, M.2
Beneke, J.3
-
13
-
-
0032128437
-
In vivo analysis of Fas/FasL interactions in HIV-infected patients
-
Badley AD, Dockrell DH, Algeciras A, et al. In vivo analysis of Fas/FasL interactions in HIV-infected patients. J Clin Invest 1998; 102:79-87.
-
(1998)
J Clin Invest
, vol.102
, pp. 79-87
-
-
Badley, A.D.1
Dockrell, D.H.2
Algeciras, A.3
-
14
-
-
0028912254
-
Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes
-
Finkel TH, Tudor-Williams G, Banda NK, et al. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes. Nat Med 1995; 1:129-134.
-
(1995)
Nat Med
, vol.1
, pp. 129-134
-
-
Finkel, T.H.1
Tudor-Williams, G.2
Banda, N.K.3
-
15
-
-
0029034517
-
Analysis of apoptosis in lymph nodes of HIV-infected persons: Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden
-
Muro-Cacho CA, Pantaleo G, Fauci AS. Analysis of apoptosis in lymph nodes of HIV-infected persons: intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden. J Immunol 1995; 154:5555-5566.
-
(1995)
J Immunol
, vol.154
, pp. 5555-5566
-
-
Muro-Cacho, C.A.1
Pantaleo, G.2
Fauci, A.S.3
-
16
-
-
0027275945
-
Lifespans of naive, memory and effector lymphocytes
-
Sprent J. Lifespans of naive, memory and effector lymphocytes. Curr Opin Immunol 1993; 5:433-438.
-
(1993)
Curr Opin Immunol
, vol.5
, pp. 433-438
-
-
Sprent, J.1
-
17
-
-
0026667222
-
Programmed death of T cells in HIV-1 infection
-
Meyaard L, Otto SA, Jonker RR, et al. Programmed death of T cells in HIV-1 infection. Science 1992; 257:217-219.
-
(1992)
Science
, vol.257
, pp. 217-219
-
-
Meyaard, L.1
Otto, S.A.2
Jonker, R.R.3
-
18
-
-
0343920019
-
T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: A longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART)
-
Hazenberg MD, Stuart JW, Otto SA, et al. T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART). Blood 2000; 95:249-255.
-
(2000)
Blood
, vol.95
, pp. 249-255
-
-
Hazenberg, M.D.1
Stuart, J.W.2
Otto, S.A.3
-
19
-
-
0032549086
-
Rapid turnover of T lymphocytes in SIV-infected rhesus macaques
-
Mohri H, Bonhoeffer S, Monard S, et al. Rapid turnover of T lymphocytes in SIV-infected rhesus macaques. Science 1998; 279:1223-1227.
-
(1998)
Science
, vol.279
, pp. 1223-1227
-
-
Mohri, H.1
Bonhoeffer, S.2
Monard, S.3
-
21
-
-
0035912232
-
The dynamics of CD4+ T-cell depletion in HIV disease
-
McCune JM. The dynamics of CD4+ T-cell depletion in HIV disease. Nature 2001; 410:974-979.
-
(2001)
Nature
, vol.410
, pp. 974-979
-
-
McCune, J.M.1
-
22
-
-
0025941375
-
Determinants of HIV disease progression: Six-year longitudinal study in the Edinburgh haemophilia/HIV cohort
-
Simmonds P, Beatson D, Cuthbert RJ, et al. Determinants of HIV disease progression: six-year longitudinal study in the Edinburgh haemophilia/HIV cohort. Lancet 1991; 338:1159-1163.
-
(1991)
Lancet
, vol.338
, pp. 1159-1163
-
-
Simmonds, P.1
Beatson, D.2
Cuthbert, R.J.3
-
23
-
-
0027304957
-
Elevated levels of CD38+ CD8+ T cells in HIV infection add to the prognostic value of low CD4+ T cell levels: Results of 6 years of follow-up. The Los Angeles Center, Multicenter AIDS Cohort Study
-
Giorgi JV, Liu Z, Hultin LE, et al. Elevated levels of CD38+ CD8+ T cells in HIV infection add to the prognostic value of low CD4+ T cell levels: results of 6 years of follow-up. The Los Angeles Center, Multicenter AIDS Cohort Study. J Acquir Immune Defic Syndr 1993; 6:904-912.
-
(1993)
J Acquir Immune Defic Syndr
, vol.6
, pp. 904-912
-
-
Giorgi, J.V.1
Liu, Z.2
Hultin, L.E.3
-
24
-
-
8944259909
-
Increased numbers of primed activated CD8+CD38+CD45RO+ T cells predict the decline of CD4+ T cells in HIV-1-infected patients
-
Bofill M, Mocroft A, Lipman M, et al. Increased numbers of primed activated CD8+CD38+CD45RO+ T cells predict the decline of CD4+ T cells in HIV-1-infected patients. AIDS 1996; 10:827-834.
-
(1996)
AIDS
, vol.10
, pp. 827-834
-
-
Bofill, M.1
Mocroft, A.2
Lipman, M.3
-
25
-
-
0025069873
-
The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1
-
Fahey JL, Taylor JM, Detels R, et al. The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1. N Engl J Med 1990; 322:166-172.
-
(1990)
N Engl J Med
, vol.322
, pp. 166-172
-
-
Fahey, J.L.1
Taylor, J.M.2
Detels, R.3
-
26
-
-
3843056825
-
Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load
-
Deeks SG, Kitchen CM, Liu L, et al. Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load. Blood 2004; 104:942-947.
-
(2004)
Blood
, vol.104
, pp. 942-947
-
-
Deeks, S.G.1
Kitchen, C.M.2
Liu, L.3
-
27
-
-
0028344901
-
Soluble receptors for tumor necrosis factor as predictors of progression to AIDS in asymptomatic human immunodeficiency virus type 1 infection
-
Godfried MH, van der Poll T, Weverling GJ, et al. Soluble receptors for tumor necrosis factor as predictors of progression to AIDS in asymptomatic human immunodeficiency virus type 1 infection. J Infect Dis 1994; 169:739-745.
-
(1994)
J Infect Dis
, vol.169
, pp. 739-745
-
-
Godfried, M.H.1
van der Poll, T.2
Weverling, G.J.3
-
28
-
-
0030296341
-
Secretion of IFN-gamma, IL-6, granulocyte-macrophage colony-stimulating factor and IL-10 cytokines after activation of human purified T lymphocytes upon CD38 ligation
-
Ausiello CM, la Sala A, Ramoni C, et al. Secretion of IFN-gamma, IL-6, granulocyte-macrophage colony-stimulating factor and IL-10 cytokines after activation of human purified T lymphocytes upon CD38 ligation. Cell Immunol 1996; 173:192-197.
-
(1996)
Cell Immunol
, vol.173
, pp. 192-197
-
-
Ausiello, C.M.1
la Sala, A.2
Ramoni, C.3
-
29
-
-
0031751647
-
Activation and cell cycle antigens in CD4+ and CD8+ T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection
-
Orendi JM, Bloem AC, Borleffs JC, et al. Activation and cell cycle antigens in CD4+ and CD8+ T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection. J Infect Dis 1998; 178:1279-1287.
-
(1998)
J Infect Dis
, vol.178
, pp. 1279-1287
-
-
Orendi, J.M.1
Bloem, A.C.2
Borleffs, J.C.3
-
30
-
-
0023951060
-
HLA haplotype A1 B8 DR3 as a risk factor for HIV-related disease
-
Steel CM, Ludlam CA, Beatson D, et al. HLA haplotype A1 B8 DR3 as a risk factor for HIV-related disease. Lancet 1988; 1:1185-1188.
-
(1988)
Lancet
, vol.1
, pp. 1185-1188
-
-
Steel, C.M.1
Ludlam, C.A.2
Beatson, D.3
-
31
-
-
0037343278
-
Nonpathogenic SIV infection of Sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia
-
Silvestri G, Sodora DL, Koup RA, et al. Nonpathogenic SIV infection of Sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia. Immunity 2003; 18:441-452.
-
(2003)
Immunity
, vol.18
, pp. 441-452
-
-
Silvestri, G.1
Sodora, D.L.2
Koup, R.A.3
-
32
-
-
0024348839
-
Spectrum of disease in macaque monkeys chronically infected with SIV/SMM
-
McClure HM, Anderson DC, Fultz PN, et al. Spectrum of disease in macaque monkeys chronically infected with SIV/SMM. Vet Immunol Immunopathol 1989; 21:13-24.
-
(1989)
Vet Immunol Immunopathol
, vol.21
, pp. 13-24
-
-
McClure, H.M.1
Anderson, D.C.2
Fultz, P.N.3
-
33
-
-
0033972359
-
Reduced immune activation and T cell apoptosis in human immunodeficiency virus type 2 compared with type 1: Correlation of T cell apoptosis with beta2 microglobulin concentration and disease evolution
-
Michel P, Balde AT, Roussilhon C, et al. Reduced immune activation and T cell apoptosis in human immunodeficiency virus type 2 compared with type 1: correlation of T cell apoptosis with beta2 microglobulin concentration and disease evolution. J Infect Dis 2000; 181:64-75.
-
(2000)
J Infect Dis
, vol.181
, pp. 64-75
-
-
Michel, P.1
Balde, A.T.2
Roussilhon, C.3
-
34
-
-
0035169609
-
Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy
-
Mohri H, Perelson AS, Tung K, et al. Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy. J Exp Med 2001; 194:1277-1287.
-
(2001)
J Exp Med
, vol.194
, pp. 1277-1287
-
-
Mohri, H.1
Perelson, A.S.2
Tung, K.3
-
35
-
-
0038701685
-
T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy
-
Hunt PW, Martin JN, Sinclair E, et al. T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy. J Infect Dis 2003; 187:1534-1543.
-
(2003)
J Infect Dis
, vol.187
, pp. 1534-1543
-
-
Hunt, P.W.1
Martin, J.N.2
Sinclair, E.3
-
36
-
-
33646883620
-
The independent effect of drug resistance on T cell activation in HIV infection
-
Hunt PW, Deeks SG, Bangsberg DR, et al. The independent effect of drug resistance on T cell activation in HIV infection. AIDS 2006; 20:691-699.
-
(2006)
AIDS
, vol.20
, pp. 691-699
-
-
Hunt, P.W.1
Deeks, S.G.2
Bangsberg, D.R.3
-
37
-
-
0030026189
-
The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation
-
Weissman D, Barker TD, Fauci AS. The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation. J Exp Med 1996; 183:687-692.
-
(1996)
J Exp Med
, vol.183
, pp. 687-692
-
-
Weissman, D.1
Barker, T.D.2
Fauci, A.S.3
-
38
-
-
0031042433
-
The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes
-
Bleul CC, Wu L, Hoxie JA, et al. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc Natl Acad Sci U S A 1997; 94:1925-1930.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 1925-1930
-
-
Bleul, C.C.1
Wu, L.2
Hoxie, J.A.3
-
39
-
-
0031662093
-
Effect of immune activation on the dynamics of human immunodeficiency virus replication and on the distribution of viral quasispecies
-
Ostrowski MA, Krakauer DC, Li Y, et al. Effect of immune activation on the dynamics of human immunodeficiency virus replication and on the distribution of viral quasispecies. J Virol 1998; 72:7772-7784.
-
(1998)
J Virol
, vol.72
, pp. 7772-7784
-
-
Ostrowski, M.A.1
Krakauer, D.C.2
Li, Y.3
-
40
-
-
33751515147
-
CD4+ count-guided interruption of antiretroviral treatment
-
Strategies for Management of Antiretroviral Therapy (SMART) Study Group, An important study reporting the increased risk of cardiovascular and other metabolic toxicities from uncontrolled HIV viremia
-
Strategies for Management of Antiretroviral Therapy (SMART) Study Group, El-Sadr WM, Lundgren JD, et al. CD4+ count-guided interruption of antiretroviral treatment. N Engl J Med 2006; 355:2283-2296. An important study reporting the increased risk of cardiovascular and other metabolic toxicities from uncontrolled HIV viremia.
-
(2006)
N Engl J Med
, vol.355
, pp. 2283-2296
-
-
El-Sadr, W.M.1
Lundgren, J.D.2
-
41
-
-
0028874048
-
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
-
Ho DD, Neumann AU, Perelson AS, et al. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 1995; 373:123-126.
-
(1995)
Nature
, vol.373
, pp. 123-126
-
-
Ho, D.D.1
Neumann, A.U.2
Perelson, A.S.3
-
42
-
-
20844450412
-
Peripheral S-phase T cells in HIV disease have a central memory phenotype and rarely have evidence of recent T cell receptor engagement
-
Sieg SF, Rodriguez B, Asaad R, et al. Peripheral S-phase T cells in HIV disease have a central memory phenotype and rarely have evidence of recent T cell receptor engagement. J Infect Dis 2005; 192:62-70.
-
(2005)
J Infect Dis
, vol.192
, pp. 62-70
-
-
Sieg, S.F.1
Rodriguez, B.2
Asaad, R.3
-
43
-
-
0035848864
-
HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell
-
Geleziunas R, Xu W, Takeda K. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature 2001; 410:834-838.
-
(2001)
Nature
, vol.410
, pp. 834-838
-
-
Geleziunas, R.1
Xu, W.2
Takeda, K.3
-
44
-
-
0029062573
-
Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein
-
Li CJ, Friedman DJ, Wang C, et al. Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 1995; 268:429-431.
-
(1995)
Science
, vol.268
, pp. 429-431
-
-
Li, C.J.1
Friedman, D.J.2
Wang, C.3
-
45
-
-
0034054026
-
Human immunodeficiency virus type 1 vpr induces apoptosis through caspase activation
-
Stewart SA, Poon B, Song JY, Chen IS. Human immunodeficiency virus type 1 vpr induces apoptosis through caspase activation. J Virol 2000; 74:3105-3111.
-
(2000)
J Virol
, vol.74
, pp. 3105-3111
-
-
Stewart, S.A.1
Poon, B.2
Song, J.Y.3
Chen, I.S.4
-
46
-
-
0029029058
-
Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120
-
Westendorp MO, Frank R, Ochsenbauer C. Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature 1995; 375:497-500.
-
(1995)
Nature
, vol.375
, pp. 497-500
-
-
Westendorp, M.O.1
Frank, R.2
Ochsenbauer, C.3
-
47
-
-
0035152177
-
Partial activation and induction of apoptosis in CD4(+) and CD8(+) T lymphocytes by conformationally authentic noninfectious human immunodeficiency virus type 1
-
Esser MT, Bess JW Jr, Suryanarayana K, et al. Partial activation and induction of apoptosis in CD4(+) and CD8(+) T lymphocytes by conformationally authentic noninfectious human immunodeficiency virus type 1. J Virol 2001; 75:1152-1164.
-
(2001)
J Virol
, vol.75
, pp. 1152-1164
-
-
Esser, M.T.1
Bess Jr, J.W.2
Suryanarayana, K.3
-
48
-
-
0034973233
-
Differential incorporation of CD45, CD80 (B7-1), CD86 (B7-2), and major histocompatibility complex class I and II molecules into human immunodeficiency virus type 1 virions and microvesicles: Implications for viral pathogenesis and immune regulation
-
Esser MT, Graham DR, Coren LV, et al. Differential incorporation of CD45, CD80 (B7-1), CD86 (B7-2), and major histocompatibility complex class I and II molecules into human immunodeficiency virus type 1 virions and microvesicles: implications for viral pathogenesis and immune regulation. J Virol 2001; 75:6173-6182.
-
(2001)
J Virol
, vol.75
, pp. 6173-6182
-
-
Esser, M.T.1
Graham, D.R.2
Coren, L.V.3
-
49
-
-
20144387661
-
Anti-inflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS
-
Kornfeld C, Ploquin MJ, Pandrea I, et al. Anti-inflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS. J Clin Invest 2005; 115:1082-1091.
-
(2005)
J Clin Invest
, vol.115
, pp. 1082-1091
-
-
Kornfeld, C.1
Ploquin, M.J.2
Pandrea, I.3
-
50
-
-
33144476838
-
Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection
-
A paper highlighting the importance of the T-regulatory cell in controlling the immune reponse
-
Estes JD, Li Q, Reynolds MR, et al. Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection. J Infect Dis 2006; 193:703-712. A paper highlighting the importance of the T-regulatory cell in controlling the immune reponse.
-
(2006)
J Infect Dis
, vol.193
, pp. 703-712
-
-
Estes, J.D.1
Li, Q.2
Reynolds, M.R.3
-
51
-
-
0036801658
-
Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis
-
Schacker TW, Nguyen PL, Beilman GJ, et al. Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis. J Clin Invest 2002; 110:1133-1139.
-
(2002)
J Clin Invest
, vol.110
, pp. 1133-1139
-
-
Schacker, T.W.1
Nguyen, P.L.2
Beilman, G.J.3
-
52
-
-
33845429615
-
-
Lederman MM, Smeaton L, Smith KY, et al. Cyclosporin A provides no sustained immunologic benefit to persons with chronic HIV-1 infection starting suppressive antiretroviral therapy: results of a randomized, controlled trial of the AIDS Clinical Trials Group A5138. J Infect Dis 2006; 194:1677-1685. A randomized, double-blind, placebo-controlled study of cyclosporine in HIV infection. Although the results were negative, the discussion provides a compelling rationale to forge ahead in this line of research.
-
Lederman MM, Smeaton L, Smith KY, et al. Cyclosporin A provides no sustained immunologic benefit to persons with chronic HIV-1 infection starting suppressive antiretroviral therapy: results of a randomized, controlled trial of the AIDS Clinical Trials Group A5138. J Infect Dis 2006; 194:1677-1685. A randomized, double-blind, placebo-controlled study of cyclosporine in HIV infection. Although the results were negative, the discussion provides a compelling rationale to forge ahead in this line of research.
-
-
-
-
53
-
-
0142092389
-
Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy
-
Guadalupe M, Reay E, Sankaran S, et al. Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J Virol 2003; 77:11708-11717.
-
(2003)
J Virol
, vol.77
, pp. 11708-11717
-
-
Guadalupe, M.1
Reay, E.2
Sankaran, S.3
-
54
-
-
4644289983
-
Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract
-
Mehandru S, Poles MA, Tenner-Racz K, et al. Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract. J Exp Med 2004; 200:761-770.
-
(2004)
J Exp Med
, vol.200
, pp. 761-770
-
-
Mehandru, S.1
Poles, M.A.2
Tenner-Racz, K.3
-
55
-
-
4644342929
-
CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
-
Brenchley JM, Schacker TW, Ruff LE, et al. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J Exp Med 2004; 200:749-759.
-
(2004)
J Exp Med
, vol.200
, pp. 749-759
-
-
Brenchley, J.M.1
Schacker, T.W.2
Ruff, L.E.3
-
56
-
-
33645924682
-
HIV disease: Fallout from a mucosal catastrophe?
-
Brenchley JM, Price DA, Douek DC. HIV disease: fallout from a mucosal catastrophe? Nat Immunol 2006; 7:235-239.
-
(2006)
Nat Immunol
, vol.7
, pp. 235-239
-
-
Brenchley, J.M.1
Price, D.A.2
Douek, D.C.3
-
57
-
-
33845532053
-
-
Brenchley JM, Price DA, Schacker TW, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006; 12:1365-1371. A paper reporting a radically different explanation for the pathogenesis of HIV-associated immune activation.
-
Brenchley JM, Price DA, Schacker TW, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006; 12:1365-1371. A paper reporting a radically different explanation for the pathogenesis of HIV-associated immune activation.
-
-
-
-
58
-
-
0035895656
-
Placebo-controlled trial of prednisone in advanced HIV-1 infection
-
McComsey GA, Whalen CC, Mawhorter SD, et al. Placebo-controlled trial of prednisone in advanced HIV-1 infection. AIDS 2001; 15:321-327.
-
(2001)
AIDS
, vol.15
, pp. 321-327
-
-
McComsey, G.A.1
Whalen, C.C.2
Mawhorter, S.D.3
-
59
-
-
0037339351
-
A study of the immunology, virology, and safety of prednisone in HIV-1-infected subjects with CD4 cell counts of 200 to 700 mm(-3)
-
Wallis RS, Kalayjian R, Jacobson JM, et al. A study of the immunology, virology, and safety of prednisone in HIV-1-infected subjects with CD4 cell counts of 200 to 700 mm(-3). J Acquir Immune Defic Syndr 2003; 32:281-286.
-
(2003)
J Acquir Immune Defic Syndr
, vol.32
, pp. 281-286
-
-
Wallis, R.S.1
Kalayjian, R.2
Jacobson, J.M.3
-
60
-
-
0037008037
-
High prevalence of osteonecrosis of the femoral head in HIV-infected adults
-
Miller KD, Masur H, Jones E, et al. High prevalence of osteonecrosis of the femoral head in HIV-infected adults. Ann Intern Med 2002; 137:17-25.
-
(2002)
Ann Intern Med
, vol.137
, pp. 17-25
-
-
Miller, K.D.1
Masur, H.2
Jones, E.3
-
61
-
-
0036192919
-
Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy
-
Rizzardi GP, Harari A, Capiluppi B, et al. Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy. J Clin Invest 2002; 109:681-688.
-
(2002)
J Clin Invest
, vol.109
, pp. 681-688
-
-
Rizzardi, G.P.1
Harari, A.2
Capiluppi, B.3
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