-
2
-
-
0032701644
-
Complexity in simplicity: Monogenic disorders and complex cardiomyopathies
-
Chen J, Chien KR. Complexity in simplicity: monogenic disorders and complex cardiomyopathies. J Clin Invest. 1999;103:1483-1485.
-
(1999)
J Clin Invest
, vol.103
, pp. 1483-1485
-
-
Chen, J.1
Chien, K.R.2
-
3
-
-
0024422923
-
Epidemiology of idiopathic dilated and hypertrophic cardiomyopathy. A population-based study in Olmsted County, Minnesota, 1975-1984
-
Codd MB, Sugrue DD, Gersh BJ, Melton LJ. Epidemiology of idiopathic dilated and hypertrophic cardiomyopathy. A population-based study in Olmsted County, Minnesota, 1975-1984. Circulation. 1989;80:564-572.
-
(1989)
Circulation
, vol.80
, pp. 564-572
-
-
Codd, M.B.1
Sugrue, D.D.2
Gersh, B.J.3
Melton, L.J.4
-
4
-
-
0032076955
-
Actin mutations in dilated cardiomyopathy, a heritable form of heart failure
-
Olson TM, Michels VV, Thibodeau SN, Tai YS, Keating MT. Actin mutations in dilated cardiomyopathy, a heritable form of heart failure. Science. 1998;280:750-752.
-
(1998)
Science
, vol.280
, pp. 750-752
-
-
Olson, T.M.1
Michels, V.V.2
Thibodeau, S.N.3
Tai, Y.S.4
Keating, M.T.5
-
5
-
-
31944450889
-
A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy
-
Haghighi K, Kolokathis F, Gramolini AO, Waggoner JR, Pater L, Lynch RA, Fan GC, Tsiapras D, Parekh RR, Dorn GW, MacLennan DH, Kremastinos DT, Kranias EG. A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy. Proc Natl Acad Sci U S A. 2006;103:1388-1393.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 1388-1393
-
-
Haghighi, K.1
Kolokathis, F.2
Gramolini, A.O.3
Waggoner, J.R.4
Pater, L.5
Lynch, R.A.6
Fan, G.C.7
Tsiapras, D.8
Parekh, R.R.9
Dorn, G.W.10
MacLennan, D.H.11
Kremastinos, D.T.12
Kranias, E.G.13
-
6
-
-
0028145745
-
A gene defect that causes conduction system disease and dilated cardiomyopathy maps to chromosome 1p1-1q1
-
Kass S, MacRae C, Graber HL, Sparks EA, McNamara D, Boudoulas H, Basson CT, Baker PB, Cody RJ, Fishman MC, Cox N, Kong A, Wooley CF, Seidman JG, Seidman CE. A gene defect that causes conduction system disease and dilated cardiomyopathy maps to chromosome 1p1-1q1. Nat Genet. 1994;7:546-551.
-
(1994)
Nat Genet
, vol.7
, pp. 546-551
-
-
Kass, S.1
MacRae, C.2
Graber, H.L.3
Sparks, E.A.4
McNamara, D.5
Boudoulas, H.6
Basson, C.T.7
Baker, P.B.8
Cody, R.J.9
Fishman, M.C.10
Cox, N.11
Kong, A.12
Wooley, C.F.13
Seidman, J.G.14
Seidman, C.E.15
-
7
-
-
0030031004
-
Mapping a cardiomyopathy locus to chromosome 3p22-p25
-
Olson TM, Keating MT. Mapping a cardiomyopathy locus to chromosome 3p22-p25. J Clin Invest. 1996;97:528-532.
-
(1996)
J Clin Invest
, vol.97
, pp. 528-532
-
-
Olson, T.M.1
Keating, M.T.2
-
8
-
-
0028801254
-
Localization of a gene responsible for familial dilated cardiomyopathy to chromosome 1q32
-
Durand JB, Bachinski LL, Bieling LC, Czernuszewicz GZ, Abchee AB, Yu QT, Tapscott T, Hill R, Ifegwu J, Marian AJ, Brugada R, Daiger S, Gregoritch JM, Anderson JL, Quiñones M, Towbin JA, Roberts R. Localization of a gene responsible for familial dilated cardiomyopathy to chromosome 1q32. Circulation. 1995;92:3387-3389.
-
(1995)
Circulation
, vol.92
, pp. 3387-3389
-
-
Durand, J.B.1
Bachinski, L.L.2
Bieling, L.C.3
Czernuszewicz, G.Z.4
Abchee, A.B.5
Yu, Q.T.6
Tapscott, T.7
Hill, R.8
Ifegwu, J.9
Marian, A.J.10
Brugada, R.11
Daiger, S.12
Gregoritch, J.M.13
Anderson, J.L.14
Quiñones, M.15
Towbin, J.A.16
Roberts, R.17
-
9
-
-
0029151478
-
Linkage of familial dilated cardiomyopathy to chromosome 9. Heart Muscle Disease Study Group
-
Krajinovic M, Pinamonti B, Sinagra G, Vatta M, Severini GM, Milasin J, Falaschi A, Camerini F, Giacca M, Mestroni L. Linkage of familial dilated cardiomyopathy to chromosome 9. Heart Muscle Disease Study Group. Am J Hum Genet. 1995;57:846-852.
-
(1995)
Am J Hum Genet
, vol.57
, pp. 846-852
-
-
Krajinovic, M.1
Pinamonti, B.2
Sinagra, G.3
Vatta, M.4
Severini, G.M.5
Milasin, J.6
Falaschi, A.7
Camerini, F.8
Giacca, M.9
Mestroni, L.10
-
10
-
-
0029565008
-
Genetic heterogeneity in familial dilated cardiomyopathy
-
Schultz KR, Gajarski RJ, Pignatelli R, Goytia V, Roberts R, Bachinski L, Towbin JA. Genetic heterogeneity in familial dilated cardiomyopathy. Biochem Mol Med. 1995;56:87-93.
-
(1995)
Biochem Mol Med
, vol.56
, pp. 87-93
-
-
Schultz, K.R.1
Gajarski, R.J.2
Pignatelli, R.3
Goytia, V.4
Roberts, R.5
Bachinski, L.6
Towbin, J.A.7
-
11
-
-
0033696881
-
Cardiomyocyte cytoskeleton and myofibrillogenesis in healthy and diseased heart
-
Ehler E, Perriard JC. Cardiomyocyte cytoskeleton and myofibrillogenesis in healthy and diseased heart. Heart Fail Rev. 2000;5:259-269.
-
(2000)
Heart Fail Rev
, vol.5
, pp. 259-269
-
-
Ehler, E.1
Perriard, J.C.2
-
12
-
-
33645643078
-
Differential regulation of cardiomyocyte survival and hypertrophy by MDM2, an E3 ubiquitin ligase
-
Toth A, Nickson P, Qin LL, Erhardt P. Differential regulation of cardiomyocyte survival and hypertrophy by MDM2, an E3 ubiquitin ligase. J Biol Chem. 2006;281:3679-3689.
-
(2006)
J Biol Chem
, vol.281
, pp. 3679-3689
-
-
Toth, A.1
Nickson, P.2
Qin, L.L.3
Erhardt, P.4
-
13
-
-
10144259344
-
MDMX: A novel p53-binding protein with some functional properties of MDM2
-
Shvarts A, Steegenga WT, Riteco N, van Laar T, Dekker P, Bazuine M, van Ham RC, van der Houven van Oordt W, Hateboer G, van der Eb AJ, Jochemsen AG. MDMX: a novel p53-binding protein with some functional properties of MDM2. EMBO J. 1996;15:5349-5357.
-
(1996)
EMBO J
, vol.15
, pp. 5349-5357
-
-
Shvarts, A.1
Steegenga, W.T.2
Riteco, N.3
van Laar, T.4
Dekker, P.5
Bazuine, M.6
van Ham, R.C.7
van der Houven van Oordt, W.8
Hateboer, G.9
van der Eb, A.J.10
Jochemsen, A.G.11
-
14
-
-
0028823020
-
-
Montes de Oca Luna R, Wagner DS, Lozano G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature. 1995;378:203-206.
-
Montes de Oca Luna R, Wagner DS, Lozano G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature. 1995;378:203-206.
-
-
-
-
15
-
-
0028834902
-
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
-
Jones SN, Roe AE, Donehower LA, Bradley A. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature. 1995;378:206-208.
-
(1995)
Nature
, vol.378
, pp. 206-208
-
-
Jones, S.N.1
Roe, A.E.2
Donehower, L.A.3
Bradley, A.4
-
16
-
-
0036606416
-
mdmx is a negative regulator of p53 activity in vivo
-
Finch RA, Donoviel DB, Potter D, Shi M, Fan A, Freed DD, Wang CY, Zambrowicz BP, Ramirez-Solis R, Sands AT, Zhang N. mdmx is a negative regulator of p53 activity in vivo. Cancer Res. 2002;62:3221-3225.
-
(2002)
Cancer Res
, vol.62
, pp. 3221-3225
-
-
Finch, R.A.1
Donoviel, D.B.2
Potter, D.3
Shi, M.4
Fan, A.5
Freed, D.D.6
Wang, C.Y.7
Zambrowicz, B.P.8
Ramirez-Solis, R.9
Sands, A.T.10
Zhang, N.11
-
17
-
-
0036311067
-
Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development
-
Migliorini D, Denchi EL, Danovi D, Jochemsen A, Capillo M, Gobbi A, Helin K, Pelicci PG, Marine JC. Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development. Mol Cell Biol. 2002;22:5527-5538.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5527-5538
-
-
Migliorini, D.1
Denchi, E.L.2
Danovi, D.3
Jochemsen, A.4
Capillo, M.5
Gobbi, A.6
Helin, K.7
Pelicci, P.G.8
Marine, J.C.9
-
18
-
-
0034863683
-
Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53
-
Parant J, Chavez-Reyes A, Little NA, Yan W, Reinke V, Jochemsen AG, Lozano G. Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53. Nat Genet. 2001;29:92-95.
-
(2001)
Nat Genet
, vol.29
, pp. 92-95
-
-
Parant, J.1
Chavez-Reyes, A.2
Little, N.A.3
Yan, W.4
Reinke, V.5
Jochemsen, A.G.6
Lozano, G.7
-
19
-
-
33644757727
-
Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development
-
Xiong S, Van Pelt CS, Elizondo-Fraire AC, Liu G, Lozano G. Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development. Proc Natl Acad Sci U S A. 2006;103:3226-3231.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3226-3231
-
-
Xiong, S.1
Van Pelt, C.S.2
Elizondo-Fraire, A.C.3
Liu, G.4
Lozano, G.5
-
20
-
-
33644778697
-
Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo
-
Francoz S, Froment P, Bogaerts S, De Clercq S, Maetens M, Doumont G, Bellefroid E, Marine JC. Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo. Proc Natl Acad Sci U S A. 2006;103:3232-3237.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3232-3237
-
-
Francoz, S.1
Froment, P.2
Bogaerts, S.3
De Clercq, S.4
Maetens, M.5
Doumont, G.6
Bellefroid, E.7
Marine, J.C.8
-
21
-
-
33751011894
-
Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death
-
Boesten LS, Zadelaar SM, De Clercq S, Francoz S, van Nieuwkoop A, Biessen EA, Hofmann F, Feil S, Feil R, Jochemsen AG, Zurcher C, Havekes LM, van Vlijmen BJ, Marine JC Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death. Cell Death Differ. 2006.
-
(2006)
Cell Death Differ
-
-
Boesten, L.S.1
Zadelaar, S.M.2
De Clercq, S.3
Francoz, S.4
van Nieuwkoop, A.5
Biessen, E.A.6
Hofmann, F.7
Feil, S.8
Feil, R.9
Jochemsen, A.G.10
Zurcher, C.11
Havekes, L.M.12
van Vlijmen, B.J.13
Marine, J.C.14
-
22
-
-
33644772395
-
Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4
-
Grier JD, Xiong S, Elizondo-Fraire AC, Parant JM, Lozano G. Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4. Mol Cell Biol. 2006;26:192-198.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 192-198
-
-
Grier, J.D.1
Xiong, S.2
Elizondo-Fraire, A.C.3
Parant, J.M.4
Lozano, G.5
-
23
-
-
0017682760
-
Interrelations of the proliferation and differentiation processes during cardiac myogenesis and regeneration
-
Rumyantsev PP. Interrelations of the proliferation and differentiation processes during cardiac myogenesis and regeneration. Int Rev Cytol. 1977;51:186-273.
-
(1977)
Int Rev Cytol
, vol.51
, pp. 186-273
-
-
Rumyantsev, P.P.1
-
24
-
-
14144253311
-
Cardiology: Solace for the broken-hearted?
-
Mummery CL. Cardiology: solace for the broken-hearted? Nature. 2005;433:585-587.
-
(2005)
Nature
, vol.433
, pp. 585-587
-
-
Mummery, C.L.1
-
25
-
-
0037205320
-
Cardiomyocyte cell cycle regulation
-
Pasumarthi KB, Field LJ. Cardiomyocyte cell cycle regulation. Circ Res. 2002;90:1044-1054.
-
(2002)
Circ Res
, vol.90
, pp. 1044-1054
-
-
Pasumarthi, K.B.1
Field, L.J.2
-
26
-
-
0035734285
-
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
-
Jonkers J, Meuwissen R, van der Gulden H, Peterse H, van der Valk M, Berns A. Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat Genet. 2001;29:418-425.
-
(2001)
Nat Genet
, vol.29
, pp. 418-425
-
-
Jonkers, J.1
Meuwissen, R.2
van der Gulden, H.3
Peterse, H.4
van der Valk, M.5
Berns, A.6
-
27
-
-
0028118111
-
Tumor spectrum analysis in p53-mutant mice
-
Jacks T, Remington L, Williams BO, Schmitt EM, Halachmi S, Bronson RT, Weinberg RA. Tumor spectrum analysis in p53-mutant mice. Current Biology. 1994;4:1-7.
-
(1994)
Current Biology
, vol.4
, pp. 1-7
-
-
Jacks, T.1
Remington, L.2
Williams, B.O.3
Schmitt, E.M.4
Halachmi, S.5
Bronson, R.T.6
Weinberg, R.A.7
-
28
-
-
18444389748
-
Telencephalon- specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development
-
Ferguson KL, Vanderluit JL, Hebert JM, McIntosh WC, Tibbo E, MacLaurin JG, Park DS, Wallace VA, Vooijs M, McConnell SK, Slack RS. Telencephalon- specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development. Embo J. 2002;21:3337-3346.
-
(2002)
Embo J
, vol.21
, pp. 3337-3346
-
-
Ferguson, K.L.1
Vanderluit, J.L.2
Hebert, J.M.3
McIntosh, W.C.4
Tibbo, E.5
MacLaurin, J.G.6
Park, D.S.7
Wallace, V.A.8
Vooijs, M.9
McConnell, S.K.10
Slack, R.S.11
-
29
-
-
0030878260
-
Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo
-
Agah R, Frenkel PA, French BA, Michael LH, Overbeek PA, Schneider MD. Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo. J Clin Invest. 1997;100:169-179.
-
(1997)
J Clin Invest
, vol.100
, pp. 169-179
-
-
Agah, R.1
Frenkel, P.A.2
French, B.A.3
Michael, L.H.4
Overbeek, P.A.5
Schneider, M.D.6
-
30
-
-
1042266632
-
On the physiological importance of endoproteolysis of CAAX proteins: Heart-specific RCE1 knockout mice develop a lethal cardiomyopathy
-
Bergo MO, Lieu HD, Gavino BJ, Ambroziak P, Otto JC, Casey PJ, Walker QM, Young SG. On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy. J Biol Chem. 2004;279:4729-4736.
-
(2004)
J Biol Chem
, vol.279
, pp. 4729-4736
-
-
Bergo, M.O.1
Lieu, H.D.2
Gavino, B.J.3
Ambroziak, P.4
Otto, J.C.5
Casey, P.J.6
Walker, Q.M.7
Young, S.G.8
-
31
-
-
11144355499
-
Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice
-
Nikolova V, Leimena C, McMahon AC, Tan JC, Chandar S, Jogia D, Kesteven SH, Michalicek J, Otway R, Verheyen F, Rainer S, Stewart CL, Martin D, Feneley MP, Fatkin D. Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice. J Clin Invest. 2004;113:357-369.
-
(2004)
J Clin Invest
, vol.113
, pp. 357-369
-
-
Nikolova, V.1
Leimena, C.2
McMahon, A.C.3
Tan, J.C.4
Chandar, S.5
Jogia, D.6
Kesteven, S.H.7
Michalicek, J.8
Otway, R.9
Verheyen, F.10
Rainer, S.11
Stewart, C.L.12
Martin, D.13
Feneley, M.P.14
Fatkin, D.15
-
32
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA Jr, Butel JS, Bradley A. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature. 1992;356:215-221.
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery Jr, C.A.5
Butel, J.S.6
Bradley, A.7
-
33
-
-
0030478367
-
Relation between gender, etiology and survival in patients with symptomatic heart failure
-
Adams KF Jr, Dunlap SH, Sueta CA, Clarke SW, Patterson JH, Blauwet MB, Jensen LR, Tomasko L, Koch G. Relation between gender, etiology and survival in patients with symptomatic heart failure. J Am Coll Cardiol. 1996;28:1781-1788.
-
(1996)
J Am Coll Cardiol
, vol.28
, pp. 1781-1788
-
-
Adams Jr, K.F.1
Dunlap, S.H.2
Sueta, C.A.3
Clarke, S.W.4
Patterson, J.H.5
Blauwet, M.B.6
Jensen, L.R.7
Tomasko, L.8
Koch, G.9
-
34
-
-
0342972604
-
Gender differences in survival in advanced heart failure. Insights from the FIRST study
-
Adams KF Jr, Sueta CA, Gheorghiade M, O'Connor CM, Schwartz TA, Koch GG, Uretsky B, Swedberg K, McKenna W, Soler-Soler J, Califf RM. Gender differences in survival in advanced heart failure. Insights from the FIRST study. Circulation. 1999;99:1816-1821.
-
(1999)
Circulation
, vol.99
, pp. 1816-1821
-
-
Adams Jr, K.F.1
Sueta, C.A.2
Gheorghiade, M.3
O'Connor, C.M.4
Schwartz, T.A.5
Koch, G.G.6
Uretsky, B.7
Swedberg, K.8
McKenna, W.9
Soler-Soler, J.10
Califf, R.M.11
-
35
-
-
13444292824
-
Clinical applications of stem cells for the heart
-
Wollert KC, Drexler H. Clinical applications of stem cells for the heart. Circ Res. 2005;96:151-163.
-
(2005)
Circ Res
, vol.96
, pp. 151-163
-
-
Wollert, K.C.1
Drexler, H.2
-
36
-
-
11144315535
-
Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors
-
Issaeva N, Bozko P, Enge M, Protopopova M, Verhoef LG, Masucci M, Pramanik A, Selivanova G. Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors. Nat Med. 2004;10:1321-1328.
-
(2004)
Nat Med
, vol.10
, pp. 1321-1328
-
-
Issaeva, N.1
Bozko, P.2
Enge, M.3
Protopopova, M.4
Verhoef, L.G.5
Masucci, M.6
Pramanik, A.7
Selivanova, G.8
-
37
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev LT, Vu BT, Graves B, Carvajal D, Podlaski F, Filipovic Z, Kong N, Kammlott U, Lukacs C, Klein C, Fotouhi N, Liu EA. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science. 2004;303:844-848.
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
Fotouhi, N.11
Liu, E.A.12
-
38
-
-
33646550549
-
MDM2 antagonists activate p53 and synergize with genotoxic drugs in B-cell chronic lymphocytic leukemia cells
-
Coll-Mulet L, Iglesias-Serret D, Santidrian AF, Cosialls AM, de Frias M, Castano E, Campas C, Barragan M, de Sevilla AF, Domingo A, Vassilev LT, Pons G, Gil J. MDM2 antagonists activate p53 and synergize with genotoxic drugs in B-cell chronic lymphocytic leukemia cells. Blood. 2006;107:4109-4114.
-
(2006)
Blood
, vol.107
, pp. 4109-4114
-
-
Coll-Mulet, L.1
Iglesias-Serret, D.2
Santidrian, A.F.3
Cosialls, A.M.4
de Frias, M.5
Castano, E.6
Campas, C.7
Barragan, M.8
de Sevilla, A.F.9
Domingo, A.10
Vassilev, L.T.11
Pons, G.12
Gil, J.13
-
39
-
-
33646574651
-
Functional integrity of the p53-mediated apoptotic pathway induced by the non-genotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL)
-
Secchiero P, Barbarotto E, Tiribelli M, Zerbinati C, di Iasio MG, Gonelli A, Cavazzini F, Campioni D, Fanin R, Cuneo A, Zauli G. Functional integrity of the p53-mediated apoptotic pathway induced by the non-genotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL). Blood. 2006;107:4122-4129.
-
(2006)
Blood
, vol.107
, pp. 4122-4129
-
-
Secchiero, P.1
Barbarotto, E.2
Tiribelli, M.3
Zerbinati, C.4
di Iasio, M.G.5
Gonelli, A.6
Cavazzini, F.7
Campioni, D.8
Fanin, R.9
Cuneo, A.10
Zauli, G.11
-
40
-
-
27644568226
-
MDM2 antagonists induce p53-dependent apoptosis in AML: Implications for leukemia therapy
-
Kojima K, Konopleva M, Samudio IJ, Shikami M, Cabreira-Hansen M, McQueen T, Ruvolo V, Tsao T, Zeng Z, Vassilev LT, Andreeff M. MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy. Blood. 2005;106:3150-3159.
-
(2005)
Blood
, vol.106
, pp. 3150-3159
-
-
Kojima, K.1
Konopleva, M.2
Samudio, I.J.3
Shikami, M.4
Cabreira-Hansen, M.5
McQueen, T.6
Ruvolo, V.7
Tsao, T.8
Zeng, Z.9
Vassilev, L.T.10
Andreeff, M.11
-
41
-
-
32444449180
-
Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: Implications for therapy
-
Tovar C, Rosinski J, Filipovic Z, Higgins B, Kolinsky K, Hilton H, Zhao X, Vu BT, Qing W, Packman K, Myklebost O, Heimbrook DC, Vassilev LT. Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy. Proc Natl Acad Sci U S A. 2006;103:1888-1893.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 1888-1893
-
-
Tovar, C.1
Rosinski, J.2
Filipovic, Z.3
Higgins, B.4
Kolinsky, K.5
Hilton, H.6
Zhao, X.7
Vu, B.T.8
Qing, W.9
Packman, K.10
Myklebost, O.11
Heimbrook, D.C.12
Vassilev, L.T.13
-
42
-
-
0035266128
-
Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53
-
Ramos YF, Stad R, Attema J, Peltenburg LT, van der Eb AJ, Jochemsen AG. Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53. Cancer Res. 2001;61:1839-1842.
-
(2001)
Cancer Res
, vol.61
, pp. 1839-1842
-
-
Ramos, Y.F.1
Stad, R.2
Attema, J.3
Peltenburg, L.T.4
van der Eb, A.J.5
Jochemsen, A.G.6
-
43
-
-
33750590095
-
Inactivation of the p53 pathway in retinoblastoma
-
Laurie NA, Donovan SL, Shih CS, Zhang J, Mills N, Fuller C, Teunisse A, Lam S, Ramos Y, Mohan A, Johnson D, Wilson M, Rodriguez-Galindo C, Quarto M, Francoz S, Mendrysa SM, Guy RK, Marine JC, Jochemsen AG, Dyer MA. Inactivation of the p53 pathway in retinoblastoma. Nature. 2006;444:61-66.
-
(2006)
Nature
, vol.444
, pp. 61-66
-
-
Laurie, N.A.1
Donovan, S.L.2
Shih, C.S.3
Zhang, J.4
Mills, N.5
Fuller, C.6
Teunisse, A.7
Lam, S.8
Ramos, Y.9
Mohan, A.10
Johnson, D.11
Wilson, M.12
Rodriguez-Galindo, C.13
Quarto, M.14
Francoz, S.15
Mendrysa, S.M.16
Guy, R.K.17
Marine, J.C.18
Jochemsen, A.G.19
Dyer, M.A.20
more..
-
44
-
-
0033531252
-
Comparative study of the p53-mdm2 and p53-MDMX interfaces
-
Bottger V, Bottger A, Garcia-Echeverria C, Ramos YF, van der Eb AJ, Jochemsen AG, Lane DP. Comparative study of the p53-mdm2 and p53-MDMX interfaces. Oncogene. 1999;18:189-199.
-
(1999)
Oncogene
, vol.18
, pp. 189-199
-
-
Bottger, V.1
Bottger, A.2
Garcia-Echeverria, C.3
Ramos, Y.F.4
van der Eb, A.J.5
Jochemsen, A.G.6
Lane, D.P.7
-
45
-
-
33845185824
-
Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo
-
Ringshausen I, O'Shea CC, Finch AJ, Swigart LB, Evan GI. Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. Cancer Cell. 2006;10:501-514.
-
(2006)
Cancer Cell
, vol.10
, pp. 501-514
-
-
Ringshausen, I.1
O'Shea, C.C.2
Finch, A.J.3
Swigart, L.B.4
Evan, G.I.5
|