A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 6, 2007, Pages 1897-1904

  Mellado, E ^a   Garcia Effron, G ^a   Alcazar Fuoli L ^a   Melchers, W J G ^b   Verweij, P E ^b   Cuenca Estrella, M ^a   Rodriguez Tudela, J L ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; AMPHOTERICIN B; ANTIFUNGAL AGENT; HISTIDINE; ITRACONAZOLE; LEUCINE; MUTANT PROTEIN; NUCLEOTIDE; POSACONAZOLE; PYRROLE; RAVUCONAZOLE; STEROL 14ALPHA DEMETHYLASE; TRIAZOLE; VORICONAZOLE;

ADOLESCENT; ADULT; AGED; ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS RESISTANCE; DNA MODIFICATION; FEMALE; FUNGAL STRAIN; FUNGUS ISOLATION; GENE AMPLIFICATION; GENE MUTATION; GENE SEQUENCE; GENETIC SUSCEPTIBILITY; HUMAN; IN VITRO STUDY; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TANDEM REPEAT;

AMINO ACID SUBSTITUTION; ANTIFUNGAL AGENTS; ASPERGILLUS FUMIGATUS; AZOLES; CYTOCHROME P-450 ENZYME SYSTEM; DRUG RESISTANCE, FUNGAL; FUNGAL PROTEINS; GENOTYPE; HUMANS; MICROBIAL SENSITIVITY TESTS; TANDEM REPEAT SEQUENCES;

EID: 34250223076     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.01092-06     Document Type: Article

References (54)

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