Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 5, 2003, Pages 1719-1726

  Nascimento, Adriana M ^a   Goldman, Gustavo H ^a   Park, Steven ^c   Marras, Salvatore A E ^c   Delmas, Guillaume ^c   Oza, Uma ^b   Lolans, Karen ^b   Dudley, Michael N ^b   Mann, Paul A ^d   Perlin, David S ^c  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Essential Therapeutics Inc   (United States)

^c PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ITRACONAZOLE; MULTIDRUG RESISTANCE PROTEIN; PYRROLE DERIVATIVE;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA SEQUENCE; DRUG TARGETING; FUNGAL STRAIN; FUNGUS CULTURE; FUNGUS ISOLATION; FUNGUS MUTANT; GENE EXPRESSION; GENE IDENTIFICATION; GENE INDUCTION; GENE MUTATION; GENE OVEREXPRESSION; IN VITRO STUDY; MOLECULAR PROBE; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; ULTRAVIOLET IRRADIATION; VIRUS GENE;

ANTIFUNGAL AGENTS; ASPERGILLUS FUMIGATUS; ATP-BINDING CASSETTE TRANSPORTERS; CLONING, MOLECULAR; DRUG RESISTANCE, MULTIPLE, FUNGAL; GENES, FUNGAL; ITRACONAZOLE; MUTATION; POLYMERASE CHAIN REACTION;

EID: 0037659190     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.5.1719-1726.2003     Document Type: Article

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