Macrophage proliferation in atherosclerosis

Current Opinion in Lipidology

Volumn 11, Issue 5, 2000, Pages 503-509

  Sakai, Masakazu ^a   Kobori, Shozo ^a   Miyazaki, Akira ^a   Horiuchi, Seikoh ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE A2; PROTEIN KINASE C;

ANIMAL CELL; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; AUTOCRINE EFFECT; CALCIUM CELL LEVEL; CELL PROLIFERATION; DNA FLANKING REGION; ENZYME ACTIVATION; GENE SEQUENCE; MACROPHAGE; MOUSE; NONHUMAN; PARACRINE SIGNALING; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; ARTERIOSCLEROSIS; CALCIUM; CELL DIVISION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; LIPOPROTEINS, LDL; MACROPHAGES; MICE; PHOSPHOLIPASES A; PROTEIN KINASE C; RECEPTORS, IMMUNOLOGIC; RECEPTORS, SCAVENGER; SIGNAL TRANSDUCTION;

EID: 0033779963     PISSN: 09579672     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041433-200010000-00008     Document Type: Review

References (65)

1. The pathogenesis of atherosclerosis: A perspective for the 1990s
2. Low density lipoprotein undergoes oxidative modification in vivo
3. Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man
4. Beyond cholesterol: Modification of low-density lipoprotein that increase its atherogenicity
5. Macrophage and smooth muscle cell proliferation in atherosclerotic lesions of WHHL and comparably hypercholesterolemic fatfed rabbits
6. Cell proliferation in human coronary arteries
7. Foam cells of the rabbit atherosclerotic plaque arrested in metaphase by colchicine show a macrophage phenotype
8. Origin and turnover of monocytes and macrophages
9. Visualization of monocyte recruitment into atherosclerotic arteries using fluorescent labelling
10. Morphology of the endothelium over atherosclerotic plaques in human coronary arteries
11. Induction of macrophage DNA synthesis by phorbol esters
12. Glucocorticoids and prostaglandins inhibit the induction of macrophage DNA synthesis by macrophage growth factor and phorbol ester
13. Interleukin 3 regulates the in vivo proliferation of both blood monocytes and peripheral exudate macrophages: Synergism between a macrophage-specific colony-stimulating factor
14. Macrophage growth factor and its relationship to colony stimulating factor
15. CSF-1-a mononuclear phagocyte lineage specific hemopoietic growth factor
16. Granulocyte/macrophage colony stimulating factor stimulates monocyte and tissue macrophage proliferation and enhances their responsiveness to macrophage colony stimulating factor
17. Keratinocyte-derived granulocyte/macrophage colony-stimulating factor induces DNA synthesis by peritoneal macrophages
18. CD 137 induces proliferation and endomitosis in monocytes
19. Effects of 1 alpha,25-dihydroxyvitamin D3 on macrophage colony-stimulating factor production and proliferation of human monocytic cells
20. Induction of GMCSF production of macrophages by advanced glycation end products of the Maillard reaction
21. Dexamethasone enhances macrophage colony stimulating factor- and granulocyte macrophage colony stimulating factor-stimulated proliferation of bone marrow-derived macrophages
22. Urea induces macrophage proliferation by inhibition of inducible nitric oxide synthesis
23. Particulate adjuvants can induce macrophage survival, DNA synthesis, and a synergic proliferative response to GM-CSF and CSF-1
24. Induction of murine macrophage growth by modified LDLs
25. Phosphatidylinositol 3-kinase is involved in the induction of macrophage growth by oxidized low density lipoprotein
26. A modification of apolipoprotein B accounts for most of the induction of macrophage growth by oxidized low density lipoprotein
27. Oxidized LDL can induce macrophage survival, DNA synthesis, and enhanced proliferative response to CSF-1 and GM-CSF
28. Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized low density lipoprotein on murine macrophages
29. The scavenger receptor serves as a route for internalization of lysophosphatidylcholine in oxidized low density lipoprotein-induced macrophage proliferation
30. Lysophosphatidylcholine potentiates the mitogenic activity of modified LDL for human monocyte-derived macrophages
31. Endocytosed lysophosphatidylcholine, through the scavenger receptor, play an essential role in oxidized low density lipoprotein-induced macrophage proliferation
32. Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils
33. A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection
34. CD36 is a receptor for oxidized low density lipoprotein
35. Expression cloning of SR-BI, a CD36-related class B scavenger receptor
36. A macrophage Fc receptor for IgG is also a receptor for oxidized low density lipoprotein
37. The 94- to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68
38. An endothelial receptor for oxidized low-density lipoprotein
39. Two intracellular signaling pathways for activation of protein kinase C are involved in oxidized low density lipoprotein-induced macrophage growth
40. Oxidized low density lipoprotein suppresses activation of NFκB in macrophages via a pertussis toxin-sensitive signaling mechanism
41. Oxidized low-density lipoprotein stimulates protein kinase C (PKC) and induces expression of PKC-isotypes via prostaglandin-H-synthase in P388D1 macrophage-like cells
42. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
43. Induction of murine macrophage growth by oxidized low density lipoprotein is mediated by granulocyte macrophage colony-stimulating factor
44. Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins
45. T-cell activation signals and human T-cell leukemia virus type I-encoded p40x protein activate the mouse granulocyte-macrophage colony-stimulating factor gene through a common DNA element
46. Sites of action of protein kinase C and phosphatidylinositol 3-kinase are distinct in oxidized low-density lipoprotein-induced macrophage proliferation
47. Calcineurin activates transcription from the GM-CSF promoter in synergy with either protein kinase C or NF-kappa B/AP-1 in T cells
48. A nuclear factor NF-GM2 that interacts with a regulatory region of the GM-CSF gene essential for its induction in responses to T-cell activation: Purification from human T-cell leukemia line Jurkat cells and similarity to NF-kappa B
49. Cis-acting DNA elements of mouse granulocyte/macrophage colony-stimulating factor gene responsive to oxidized low density lipoprotein
50. Oxidized LDL induces transcription factor activator protein-1 but inhibits activation of nuclear factor-kappa B in human vascular smooth muscle cells
51. NF-kappa B as inducible transcriptional activator of the granulocyte-macrophage colony-stimulating factor gene
52. Nuclear proteins interacting with the promoter region of the human granulocyte/macrophage colony-stimulating factor gene
53. Activation of the granulocyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors
54. The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLEO mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT
55. Glucocorticoid inhibits oxidized low-density lipoprotein-induced macrophage growth by suppressing the expression of granulocyte/macrophage colony-stimulating factor
56. Atherosclerosis - An inflammatory disease
57. 2 in human atherosclerotic plaques
58. 2 in atherosclerosis
59. 2 expression in human aortic tissue in dependence on the degree of atherosclerosis
60. 2 from an inflammatory exudate
61. 2 in normal and atherosclerotic arteries
62. In situ proliferation of intratumor macrophages
63. Alveolar macrophage replication: One mechanism for the expansion of the mononuclear phagocyte population in the chronically inflamed lung
64. 2 in the pathology of disease
65. 2 enhances oxidized low density lipoprotein-induced macrophage growth through enhancement of GM-GSF release