-
1
-
-
0036272136
-
Hedgehog in the human: A possible explanation for the VATER association
-
Arsic D, Qi BQ, Beasley SW. Hedgehog in the human: a possible explanation for the VATER association. J. Paediatr. Child Health 2002 38: 117 21.
-
(2002)
J. Paediatr. Child Health
, vol.38
, pp. 117-21
-
-
Arsic, D.1
Qi, B.Q.2
Beasley, S.W.3
-
2
-
-
0028641336
-
Autoproteolysis in hedgehog protein biogenesis
-
Lee JJ, Ekker SC, von Kessler DP, Porter JA, Sun BI, Beachy PA. Autoproteolysis in hedgehog protein biogenesis. Science 1994 266: 1528 37.
-
(1994)
Science
, vol.266
, pp. 1528-37
-
-
Lee, J.J.1
Ekker, S.C.2
Von Kessler, D.P.3
Porter, J.A.4
Sun, B.I.5
Beachy, P.A.6
-
3
-
-
0028948811
-
The product of hedgehog autoproteolytic cleavage active in local and long-range signalling
-
Porter JA, von Kessler DP, Ekker SC et al. The product of hedgehog autoproteolytic cleavage active in local and long-range signalling. Nature 1995 374: 363 6.
-
(1995)
Nature
, vol.374
, pp. 363-6
-
-
Porter, J.A.1
Von Kessler, D.P.2
Ekker, S.C.3
-
4
-
-
0029004233
-
Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis
-
Roelink H, Porter JA, Chiang C et al. Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis. Cell 1995 81: 445 55.
-
(1995)
Cell
, vol.81
, pp. 445-55
-
-
Roelink, H.1
Porter, J.A.2
Chiang, C.3
-
5
-
-
0029948270
-
Biochemical evidence that patched is the Hedgehog receptor
-
Marigo V, Davey RA, Zuo Y, Cunningham JM, Tabin CJ. Biochemical evidence that patched is the Hedgehog receptor. Nature 1996 384: 176 9.
-
(1996)
Nature
, vol.384
, pp. 176-9
-
-
Marigo, V.1
Davey, R.A.2
Zuo, Y.3
Cunningham, J.M.4
Tabin, C.J.5
-
6
-
-
0033604515
-
Hedgehog signal transduction: From flies to vertebrates
-
Murone M, Rosenthal A, de Sauvage FJ. Hedgehog signal transduction: from flies to vertebrates. Exp. Cell Res. 1999 253: 25 33.
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 25-33
-
-
Murone, M.1
Rosenthal, A.2
De Sauvage, F.J.3
-
7
-
-
0034055649
-
Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation
-
Park HL, Bai C, Platt KA et al. Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development 2000 127: 1593 605.
-
(2000)
Development
, vol.127
, pp. 1593-605
-
-
Park, H.L.1
Bai, C.2
Platt, K.A.3
-
8
-
-
0032848136
-
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: Implication of Gli2 and Gli3 as primary mediators of Shh signaling
-
Sasaki H, Nishizaki Y, Hui C, Nakafuku M, Kondoh H. Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. Development 1999 126: 3915 24.
-
(1999)
Development
, vol.126
, pp. 3915-24
-
-
Sasaki, H.1
Nishizaki, Y.2
Hui, C.3
Nakafuku, M.4
Kondoh, H.5
-
9
-
-
0033203419
-
The works of GLI and the power of hedgehog
-
Ruiz IAA. The works of GLI and the power of hedgehog. Nat. Cell Biol. 1999 1: E147 8.
-
(1999)
Nat. Cell Biol.
, vol.1
-
-
Ruiz, I.A.A.1
-
10
-
-
0036559186
-
Gli and hedgehog in cancer: Tumours, embryos and stem cells
-
Ruiz i Altaba A, Sanchez P, Dahmane N. Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat. Rev. Cancer 2002 2: 361 72.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 361-72
-
-
Ruiz Altaba, I.A.1
Sanchez, P.2
Dahmane, N.3
-
11
-
-
0031587830
-
Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor
-
Aza-Blanc P, Ramirez-Weber FA, Laget MP, Schwartz C, Kornberg TB. Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor. Cell 1997 89: 1043 53.
-
(1997)
Cell
, vol.89
, pp. 1043-53
-
-
Aza-Blanc, P.1
Ramirez-Weber, F.A.2
Laget, M.P.3
Schwartz, C.4
Kornberg, T.B.5
-
12
-
-
0033761448
-
Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities
-
Aza-Blanc P, Lin HY, Ruiz i Altaba A, Kornberg TB. Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities. Development 2000 127: 4293 301.
-
(2000)
Development
, vol.127
, pp. 4293-301
-
-
Aza-Blanc, P.1
Lin, H.Y.2
Ruiz Altaba, I.A.3
Kornberg, T.B.4
-
13
-
-
0027756145
-
Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
-
Echelard Y, Epstein DJ, St-Jacques B et al. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 1993 75: 1417 30.
-
(1993)
Cell
, vol.75
, pp. 1417-30
-
-
Echelard, Y.1
Epstein, D.J.2
St-Jacques, B.3
-
14
-
-
0032126734
-
Transducing Hedgehog: The story so far
-
Ingham PW. Transducing Hedgehog: the story so far. EMBO J. 1998 17: 3505 11.
-
(1998)
EMBO J.
, vol.17
, pp. 3505-11
-
-
Ingham, P.W.1
-
16
-
-
0031938114
-
Sonic hedgehog expression in developing chicken digestive organs is regulated by epithelial-mesenchymal interactions
-
Narita T, Ishii Y, Nohno T, Noji S, Yasugi S. Sonic hedgehog expression in developing chicken digestive organs is regulated by epithelial-mesenchymal interactions. Dev. Growth Differ. 1998 40: 67 74.
-
(1998)
Dev. Growth Differ.
, vol.40
, pp. 67-74
-
-
Narita, T.1
Ishii, Y.2
Nohno, T.3
Noji, S.4
Yasugi, S.5
-
17
-
-
0028837742
-
Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo
-
Bitgood MJ, McMahon AP. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev. Biol. 1995 172: 126 38.
-
(1995)
Dev. Biol.
, vol.172
, pp. 126-38
-
-
Bitgood, M.J.1
McMahon, A.P.2
-
18
-
-
0029777408
-
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
-
Chiang C, Litingtung Y, Lee E et al. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 1996 383: 407 13.
-
(1996)
Nature
, vol.383
, pp. 407-13
-
-
Chiang, C.1
Litingtung, Y.2
Lee, E.3
-
19
-
-
0031683165
-
Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus
-
Motoyama J, Liu J, Mo R, Ding Q, Post M, Hui CC. Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus. Nat. Genet. 1998 20: 54 7.
-
(1998)
Nat. Genet.
, vol.20
, pp. 54-7
-
-
Motoyama, J.1
Liu, J.2
Mo, R.3
Ding, Q.4
Post, M.5
Hui, C.C.6
-
20
-
-
10944250238
-
Adriamycin disruption of the Shh-Gli pathway is associated with abnormalities of foregut development
-
Arsic D, Cameron V, Ellmers L, Quan QB, Keenan J, Beasley S. Adriamycin disruption of the Shh-Gli pathway is associated with abnormalities of foregut development. J. Pediatr. Surg. 2004 39: 1747 53.
-
(2004)
J. Pediatr. Surg.
, vol.39
, pp. 1747-53
-
-
Arsic, D.1
Cameron, V.2
Ellmers, L.3
Quan, Q.B.4
Keenan, J.5
Beasley, S.6
-
21
-
-
0042338649
-
Differences in the levels of Sonic hedgehog protein during early foregut development caused by exposure to Adriamycin give clues to the role of the Shh gene in oesophageal atresia
-
Arsic D, Keenan J, Beasley SW, Qi BQ. Differences in the levels of Sonic hedgehog protein during early foregut development caused by exposure to Adriamycin give clues to the role of the Shh gene in oesophageal atresia. Pediatr. Surg. Int. 2003 19: 463 6.
-
(2003)
Pediatr. Surg. Int.
, vol.19
, pp. 463-6
-
-
Arsic, D.1
Keenan, J.2
Beasley, S.W.3
Qi, B.Q.4
-
22
-
-
0037118056
-
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin e
-
Duman-Scheel M, Weng L, Xin S, Du W. Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E. Nature 2002 417: 299 304.
-
(2002)
Nature
, vol.417
, pp. 299-304
-
-
Duman-Scheel, M.1
Weng, L.2
Xin, S.3
Du, W.4
-
23
-
-
0028878117
-
Nevoid basal cell carcinoma syndrome
-
Gorlin RJ. Nevoid basal cell carcinoma syndrome. Dermatol. Clin. 1995 13: 113 25.
-
(1995)
Dermatol. Clin.
, vol.13
, pp. 113-25
-
-
Gorlin, R.J.1
-
24
-
-
0030844141
-
Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours
-
Dahmane N, Lee J, Robins P, Heller P, Ruiz i Altaba A. Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours. Nature 1997 389: 876 81.
-
(1997)
Nature
, vol.389
, pp. 876-81
-
-
Dahmane, N.1
Lee, J.2
Robins, P.3
Heller, P.4
Ruiz Altaba, I.A.5
-
25
-
-
0031913524
-
Activating Smoothened mutations in sporadic basal-cell carcinoma
-
Xie J, Murone M, Luoh SM et al. Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature 1998 391: 90 2.
-
(1998)
Nature
, vol.391
, pp. 90-2
-
-
Xie, J.1
Murone, M.2
Luoh, S.M.3
-
26
-
-
0032080853
-
Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system
-
Reifenberger J, Wolter M, Weber RG et al. Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res. 1998 58: 1798 803.
-
(1998)
Cancer Res.
, vol.58
, pp. 1798-803
-
-
Reifenberger, J.1
Wolter, M.2
Weber, R.G.3
-
27
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson RL, Rothman AL, Xie J et al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 1996 272: 1668 71.
-
(1996)
Science
, vol.272
, pp. 1668-71
-
-
Johnson, R.L.1
Rothman, A.L.2
Xie, J.3
-
28
-
-
0031837454
-
Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome
-
Hahn H, Wojnowski L, Zimmer AM, Hall J, Miller G, Zimmer A. Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome. Nat. Med. 1998 4: 619 22.
-
(1998)
Nat. Med.
, vol.4
, pp. 619-22
-
-
Hahn, H.1
Wojnowski, L.2
Zimmer, A.M.3
Hall, J.4
Miller, G.5
Zimmer, A.6
-
29
-
-
2942533929
-
Hedgehog signalling in colorectal tumour cells: Induction of apoptosis with cyclopamine treatment
-
Qualtrough D, Buda A, Gaffield W, Williams AC, Paraskeva C. Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment. Int. J. Cancer 2004 110: 831 7.
-
(2004)
Int. J. Cancer
, vol.110
, pp. 831-7
-
-
Qualtrough, D.1
Buda, A.2
Gaffield, W.3
Williams, A.C.4
Paraskeva, C.5
-
30
-
-
4344659678
-
Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling
-
Sanchez P, Hernandez AM, Stecca B et al. Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling. Proc. Natl. Acad. Sci. USA 2004 101: 12561 6.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 12561-6
-
-
Sanchez, P.1
Hernandez, A.M.2
Stecca, B.3
-
31
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
Thayer SP, di Magliano MP, Heiser PW et al. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 2003 425: 851 6.
-
(2003)
Nature
, vol.425
, pp. 851-6
-
-
Thayer, S.P.1
Di Magliano, M.P.2
Heiser, P.W.3
-
32
-
-
0141834796
-
Hedgehog signaling: Progenitor phenotype in small-cell lung cancer
-
Watkins DN, Berman DM, Baylin SB. Hedgehog signaling: progenitor phenotype in small-cell lung cancer. Cell Cycle 2003 2: 196 8.
-
(2003)
Cell Cycle
, vol.2
, pp. 196-8
-
-
Watkins, D.N.1
Berman, D.M.2
Baylin, S.B.3
-
33
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
Berman DM, Karhadkar SS, Maitra A et al. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 2003 425: 846 51.
-
(2003)
Nature
, vol.425
, pp. 846-51
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
-
34
-
-
0036829397
-
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
-
Chen JK, Taipale J, Cooper MK, Beachy PA. Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev. 2002 16: 2743 8.
-
(2002)
Genes Dev.
, vol.16
, pp. 2743-8
-
-
Chen, J.K.1
Taipale, J.2
Cooper, M.K.3
Beachy, P.A.4
|