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Volumn 21, Issue 4, 2007, Pages 316-320

Study of disease-relevant polymorphisms in the TLR4 and TLR9 genes: A novel method applied to the analysis of the Portuguese population

Author keywords

Bi PASA; Polymorphism; Toll like receptor

Indexed keywords

TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9;

EID: 34248176306     PISSN: 08908508     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcp.2007.03.005     Document Type: Article
Times cited : (22)

References (36)
  • 1
    • 0033975869 scopus 로고    scopus 로고
    • Innate immune recognition: mechanisms and pathways
    • Medzhitov R., and Janeway Jr. C. Innate immune recognition: mechanisms and pathways. Immunol Rev 173 (2000) 89-97
    • (2000) Immunol Rev , vol.173 , pp. 89-97
    • Medzhitov, R.1    Janeway Jr., C.2
  • 2
    • 0034307339 scopus 로고    scopus 로고
    • The Toll receptor family and microbial recognition
    • Medzhitov R., and Janeway Jr. C. The Toll receptor family and microbial recognition. Trends Microbiol 8 (2000) 452-456
    • (2000) Trends Microbiol , vol.8 , pp. 452-456
    • Medzhitov, R.1    Janeway Jr., C.2
  • 3
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R., Preston-Hurlburt P., and Janeway Jr. C.A. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388 (1997) 394-397
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 4
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
    • Poltorak A., He X., Smirnova I., Liu M.Y., Van H.C., Du X., et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282 (1998) 2085-2088
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1    He, X.2    Smirnova, I.3    Liu, M.Y.4    Van, H.C.5    Du, X.6
  • 5
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product
    • Hoshino K., Takeuchi O., Kawai T., Sanjo H., Ogawa T., Takeda Y., et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol 162 (1999) 3749-3752
    • (1999) J Immunol , vol.162 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3    Sanjo, H.4    Ogawa, T.5    Takeda, Y.6
  • 6
    • 0035953543 scopus 로고    scopus 로고
    • The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
    • Hayashi F., Smith K.D., Ozinsky A., Hawn T.R., Yi E.C., Goodlett D.R., et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410 (2001) 1099-1103
    • (2001) Nature , vol.410 , pp. 1099-1103
    • Hayashi, F.1    Smith, K.D.2    Ozinsky, A.3    Hawn, T.R.4    Yi, E.C.5    Goodlett, D.R.6
  • 7
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • Alexopoulou L., Holt A.C., Medzhitov R., and Flavell R.A. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413 (2001) 732-738
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 9
    • 0036453356 scopus 로고    scopus 로고
    • TLR2: cellular sensor for microbial and endogenous molecular patterns
    • Kirschning C.J., and Schumann R.R. TLR2: cellular sensor for microbial and endogenous molecular patterns. Curr Top Microbiol Immunol 270 (2002) 121-144
    • (2002) Curr Top Microbiol Immunol , vol.270 , pp. 121-144
    • Kirschning, C.J.1    Schumann, R.R.2
  • 10
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: critical proteins linking innate and acquired immunity
    • Akira S., Takeda K., and Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2 (2001) 675-680
    • (2001) Nat Immunol , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 11
    • 0034084438 scopus 로고    scopus 로고
    • TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
    • Arbour N.C., Lorenz E., Schutte B.C., Zabner J., Kline J.N., Jones M., et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 25 (2000) 187-191
    • (2000) Nat Genet , vol.25 , pp. 187-191
    • Arbour, N.C.1    Lorenz, E.2    Schutte, B.C.3    Zabner, J.4    Kline, J.N.5    Jones, M.6
  • 12
    • 0037111078 scopus 로고    scopus 로고
    • Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections
    • Agnese D.M., Calvano J.E., Hahm S.J., Coyle S.M., Corbett S.A., Calvano S.E., et al. Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections. J Infect Dis 186 (2002) 1522-1525
    • (2002) J Infect Dis , vol.186 , pp. 1522-1525
    • Agnese, D.M.1    Calvano, J.E.2    Hahm, S.J.3    Coyle, S.M.4    Corbett, S.A.5    Calvano, S.E.6
  • 13
    • 0037071251 scopus 로고    scopus 로고
    • Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock
    • Lorenz E., Mira J.P., Frees K.L., and Schwartz D.A. Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch Intern Med 162 (2002) 1028-1032
    • (2002) Arch Intern Med , vol.162 , pp. 1028-1032
    • Lorenz, E.1    Mira, J.P.2    Frees, K.L.3    Schwartz, D.A.4
  • 14
    • 0036838272 scopus 로고    scopus 로고
    • Role of the toll-like receptor 4 Asp299Gly polymorphism in susceptibility to Candida albicans infection
    • Morre S.A., Murillo L.S., Spaargaren J., Fennema H.S., and Pena A.S. Role of the toll-like receptor 4 Asp299Gly polymorphism in susceptibility to Candida albicans infection. J Infect Dis 186 (2002) 1377-1379
    • (2002) J Infect Dis , vol.186 , pp. 1377-1379
    • Morre, S.A.1    Murillo, L.S.2    Spaargaren, J.3    Fennema, H.S.4    Pena, A.S.5
  • 15
    • 7544221703 scopus 로고    scopus 로고
    • The toll-like receptor 4 Asp299Gly variant: no influence on LPS responsiveness or susceptibility to pulmonary tuberculosis in The Gambia
    • Newport M.J., Allen A., Awomoyi A.A., Dunstan S.J., McKinney E., Marchant A., et al. The toll-like receptor 4 Asp299Gly variant: no influence on LPS responsiveness or susceptibility to pulmonary tuberculosis in The Gambia. Tuberculosis (Edinb) 84 (2004) 347-352
    • (2004) Tuberculosis (Edinb) , vol.84 , pp. 347-352
    • Newport, M.J.1    Allen, A.2    Awomoyi, A.A.3    Dunstan, S.J.4    McKinney, E.5    Marchant, A.6
  • 16
    • 0035450762 scopus 로고    scopus 로고
    • A functional polymorphism of toll-like receptor 4 is not associated with likelihood or severity of meningococcal disease
    • Read R.C., Pullin J., Gregory S., Borrow R., Kaczmarski E.B., di Giovine F.S., et al. A functional polymorphism of toll-like receptor 4 is not associated with likelihood or severity of meningococcal disease. J Infect Dis 184 (2001) 640-642
    • (2001) J Infect Dis , vol.184 , pp. 640-642
    • Read, R.C.1    Pullin, J.2    Gregory, S.3    Borrow, R.4    Kaczmarski, E.B.5    di Giovine, F.S.6
  • 17
    • 0037289001 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies
    • Lazarus R., Klimecki W.T., Raby B.A., Vercelli D., Palmer L.J., Kwiatkowski D.J., et al. Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies. Genomics 81 (2003) 85-91
    • (2003) Genomics , vol.81 , pp. 85-91
    • Lazarus, R.1    Klimecki, W.T.2    Raby, B.A.3    Vercelli, D.4    Palmer, L.J.5    Kwiatkowski, D.J.6
  • 19
    • 33646340664 scopus 로고    scopus 로고
    • Genetic variation in Toll-like receptor 9 and susceptibility to systemic lupus erythematosus
    • De Jager P., Richardson A., Vyse T., and Rioux J. Genetic variation in Toll-like receptor 9 and susceptibility to systemic lupus erythematosus. Arthritis Rheum 54 (2006) 1279-1282
    • (2006) Arthritis Rheum , vol.54 , pp. 1279-1282
    • De Jager, P.1    Richardson, A.2    Vyse, T.3    Rioux, J.4
  • 20
    • 33644811344 scopus 로고    scopus 로고
    • Common human Toll-like receptor 9 polymorphisms and haplotypes: association with atopy and functional relevance
    • Berghofer B., Frommer T., Konig I.R., Ziegler A., Chakraborty T., Bein G., et al. Common human Toll-like receptor 9 polymorphisms and haplotypes: association with atopy and functional relevance. Clin Exp Allergy 35 (2005) 1147-1154
    • (2005) Clin Exp Allergy , vol.35 , pp. 1147-1154
    • Berghofer, B.1    Frommer, T.2    Konig, I.R.3    Ziegler, A.4    Chakraborty, T.5    Bein, G.6
  • 21
    • 1242351229 scopus 로고    scopus 로고
    • Rapid and inexpensive real-time PCR for genotyping functional polymorphisms within the Toll-like receptor -2, -4, and -9 genes
    • Hamann L., Hamprecht A., Gomma A., and Schumann R.R. Rapid and inexpensive real-time PCR for genotyping functional polymorphisms within the Toll-like receptor -2, -4, and -9 genes. J Immunol Methods 285 (2004) 281-291
    • (2004) J Immunol Methods , vol.285 , pp. 281-291
    • Hamann, L.1    Hamprecht, A.2    Gomma, A.3    Schumann, R.R.4
  • 22
    • 3142534408 scopus 로고    scopus 로고
    • Single step high-throughput determination of Toll-like receptor 4 polymorphisms
    • van Rijn B.B., Roest M., Franx A., Bruinse H.W., and Voorbij H.A. Single step high-throughput determination of Toll-like receptor 4 polymorphisms. J Immunol Methods 289 (2004) 81-87
    • (2004) J Immunol Methods , vol.289 , pp. 81-87
    • van Rijn, B.B.1    Roest, M.2    Franx, A.3    Bruinse, H.W.4    Voorbij, H.A.5
  • 23
    • 0036790341 scopus 로고    scopus 로고
    • Polymorphisms of TLR4: rapid genotyping and reduced response to lipopolysaccharide of TLR4 mutant alleles
    • Schmitt C., Humeny A., Becker C.M., Brune K., and Pahl A. Polymorphisms of TLR4: rapid genotyping and reduced response to lipopolysaccharide of TLR4 mutant alleles. Clin Chem 48 (2002) 1661-1667
    • (2002) Clin Chem , vol.48 , pp. 1661-1667
    • Schmitt, C.1    Humeny, A.2    Becker, C.M.3    Brune, K.4    Pahl, A.5
  • 24
    • 0034960348 scopus 로고    scopus 로고
    • Determination of the TLR4 genotype using allele-specific PCR
    • Lorenz E., Frees K.L., and Schwartz D.A. Determination of the TLR4 genotype using allele-specific PCR. Biotechniques 31 (2001) 22-24
    • (2001) Biotechniques , vol.31 , pp. 22-24
    • Lorenz, E.1    Frees, K.L.2    Schwartz, D.A.3
  • 25
    • 0037505640 scopus 로고    scopus 로고
    • Rapid and reliable genotyping for the Toll-like receptor 4 A896G polymorphism using fluorescence-labeled hybridization probes in a real-time polymerase chain reaction assay
    • Heesen M., Wessiepe M., Kunz D., Vasickova K., and Blomeke B. Rapid and reliable genotyping for the Toll-like receptor 4 A896G polymorphism using fluorescence-labeled hybridization probes in a real-time polymerase chain reaction assay. Clin Chim Acta 333 (2003) 47-49
    • (2003) Clin Chim Acta , vol.333 , pp. 47-49
    • Heesen, M.1    Wessiepe, M.2    Kunz, D.3    Vasickova, K.4    Blomeke, B.5
  • 26
    • 0030977752 scopus 로고    scopus 로고
    • Overlapping PCR for bidirectional PCR amplification of specific alleles: a rapid one-tube method for simultaneously differentiating homozygotes and heterozygotes
    • Liu Q., Thorland E.C., Heit J.A., and Sommer S.S. Overlapping PCR for bidirectional PCR amplification of specific alleles: a rapid one-tube method for simultaneously differentiating homozygotes and heterozygotes. Genome Res 7 (1997) 389-398
    • (1997) Genome Res , vol.7 , pp. 389-398
    • Liu, Q.1    Thorland, E.C.2    Heit, J.A.3    Sommer, S.S.4
  • 27
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller S.A., Dykes D.D., and Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16 (1988) 1215
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 28
    • 28444464798 scopus 로고    scopus 로고
    • Mutations in TLR4 signaling that lead to increased susceptibility to infection in humans: an overview
    • Vogel S.N., Awomoyi A.A., Rallabhandi P., and Medvedev A.E. Mutations in TLR4 signaling that lead to increased susceptibility to infection in humans: an overview. J Endotoxin Res 11 (2005) 333-339
    • (2005) J Endotoxin Res , vol.11 , pp. 333-339
    • Vogel, S.N.1    Awomoyi, A.A.2    Rallabhandi, P.3    Medvedev, A.E.4
  • 29
    • 0034858250 scopus 로고    scopus 로고
    • Excess of rare amino acid polymorphisms in the Toll-like receptor 4 in humans
    • Smirnova I., Hamblin M.T., McBride C., Beutler B., and Di R.A. Excess of rare amino acid polymorphisms in the Toll-like receptor 4 in humans. Genetics 158 (2001) 1657-1664
    • (2001) Genetics , vol.158 , pp. 1657-1664
    • Smirnova, I.1    Hamblin, M.T.2    McBride, C.3    Beutler, B.4    Di, R.A.5
  • 30
    • 19944415253 scopus 로고    scopus 로고
    • Polymorphisms of genes involved in innate immunity: association with preterm delivery
    • Hartel C., Finas D., Ahrens P., Kattner E., Schaible T., Muller D., et al. Polymorphisms of genes involved in innate immunity: association with preterm delivery. Mol Hum Reprod 10 (2004) 911-915
    • (2004) Mol Hum Reprod , vol.10 , pp. 911-915
    • Hartel, C.1    Finas, D.2    Ahrens, P.3    Kattner, E.4    Schaible, T.5    Muller, D.6
  • 31
    • 2542485274 scopus 로고    scopus 로고
    • Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus disease
    • Tal G., Mandelberg A., Dalal I., Cesar K., Somekh E., Tal A., et al. Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus disease. J Infect Dis 189 (2004) 2057-2063
    • (2004) J Infect Dis , vol.189 , pp. 2057-2063
    • Tal, G.1    Mandelberg, A.2    Dalal, I.3    Cesar, K.4    Somekh, E.5    Tal, A.6
  • 32
    • 85047684648 scopus 로고    scopus 로고
    • Association between the Asp299Gly polymorphisms in the Toll-like receptor 4 and premature births in the Finnish population
    • Lorenz E., Hallman M., Marttila R., Haataja R., and Schwartz D.A. Association between the Asp299Gly polymorphisms in the Toll-like receptor 4 and premature births in the Finnish population. Pediatr Res 52 (2002) 373-376
    • (2002) Pediatr Res , vol.52 , pp. 373-376
    • Lorenz, E.1    Hallman, M.2    Marttila, R.3    Haataja, R.4    Schwartz, D.A.5
  • 33
    • 4043067215 scopus 로고    scopus 로고
    • Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction
    • Edfeldt K., Bennet A.M., Eriksson P., Frostegard J., Wiman B., Hamsten A., et al. Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction. Eur Heart J 25 (2004) 1447-1453
    • (2004) Eur Heart J , vol.25 , pp. 1447-1453
    • Edfeldt, K.1    Bennet, A.M.2    Eriksson, P.3    Frostegard, J.4    Wiman, B.5    Hamsten, A.6
  • 34
    • 14044259411 scopus 로고    scopus 로고
    • Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
    • Hawn T.R., Verbon A., Janer M., Zhao L.P., Beutler B., and Aderem A. Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease. Proc Natl Acad Sci USA 102 (2005) 2487-2489
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2487-2489
    • Hawn, T.R.1    Verbon, A.2    Janer, M.3    Zhao, L.P.4    Beutler, B.5    Aderem, A.6
  • 36
    • 30444459750 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria
    • Mockenhaupt F.P., Cramer J.P., Hamann L., Stegemann M.S., Eckert J., Oh N.R., et al. Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria. Proc Natl Acad Sci USA 103 (2006) 177-182
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 177-182
    • Mockenhaupt, F.P.1    Cramer, J.P.2    Hamann, L.3    Stegemann, M.S.4    Eckert, J.5    Oh, N.R.6


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